Abstract:
:The diurnal variation in lysosomal acid cholesteryl ester hydrolase (Acid CEH), (EC 3.1.1.13) has been examined in fed, fasted and adrenalectomized rats. The Acid CEH activity of normal rat liver exhibits a diurnal rhythm with maxima at 06.00 hours and minima at 18.00 hours, but such a rhythm was not observed in spleen and brain. This rhythm was abolished after fasting for two days, and the resulting Acid CEH activity remained constant at the minimum level. However, adrenalectomy did not abolish the diurnal rhythm. These results indicate that the Acid CEH activity varies according to a diurnal rhythm with maxima and minima separated by approximately 12 hr. Further, it is evident that the appearance of this rhythm is dependent upon dietary, but not adrenal hormone influence.
journal_name
Lipidsjournal_title
Lipidsauthors
Tanaka M,Yonekura R,Iio T,Tabata Tdoi
10.1007/BF02534362subject
Has Abstractpub_date
1985-01-01 00:00:00pages
46-8issue
1eissn
0024-4201issn
1558-9307journal_volume
20pub_type
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