Cholesteryl ester hydrolase activity in human symptomatic atherosclerosis.

Abstract:

:Acid cholesteryl ester hydrolase (CEH) activity was assayed in mononuclear cells of patients with symptomatic atherosclerosis (transient ischemic attacks, TIA) and in age-matched controls showing no evidence of atherosclerosis. The acid CEH level of TIA patients was significantly lower than that of controls (1074 +/- 128 vs 2113 +/- 255 pmol/mg P/hr, mean +/- SE). Neither mononuclear cell nor plasma cholesterol and cholesteryl ester concentrations differed significantly between atherosclerotic and control groups. TIA women had lower mononuclear cell concentrations of free cholesterol than men.

journal_name

Lipids

journal_title

Lipids

authors

Yatsu FM,Hagemenas FC,Manaugh LC,Galambos T

doi

10.1007/BF02534317

subject

Has Abstract

pub_date

1980-12-01 00:00:00

pages

1019-22

issue

12

eissn

0024-4201

issn

1558-9307

journal_volume

15

pub_type

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