Polyunsaturated fatty acids in tissues of rats fed trielaidin and high or low levels of linolenic acid.

Abstract:

:Male and female weanling rats that were born to dams fed a diet low in linolenic acid received diets of 15% lipids by weight containing 45% elaidic acid (as trielaidin) and 8.5% or 0.1% linolenic acid for 10 weeks. Four other groups, in which palmitic or oleic acid replaced elaidic acid in the diet, served as controls. The fatty acid profiles of several lipid classes were determined in adipose tissue, adrenals, testes, heart and brain. Elaidic acid was incorporated into tissue lipids in varying degrees, depending on the organ and on the lipid class. Feeding elaidic acid induced no changes in the polyunsaturated fatty acid (PUFA) profiles of testes lipids but resulted in definite modifications of the PUFA patterns of heart phosphatidylcholine (PC) and phosphatidylethanolamine (PE). In linolenic acid-deprived rats, arachidonic acid was decreased in PC and linoleic acid was increased in both PC and PE; 22:5n-6 was strongly depressed in both PC and PE. In linolenic acid-fed rats, 22:6n-3 was decreased in PC and PE. These changes, on the whole, were more evident in females, and some also were observed in adrenal cholesteryl esters but only slightly in brain phospholipids. The apparent inhibition of the biosynthesis of PUFA induced by dietary elaidic acid appeared to be complex and of greater intensity in the n-6 fatty acid series than in their n-3 homologues.

journal_name

Lipids

journal_title

Lipids

authors

Astorg PO,Chevalier J

doi

10.1007/BF02536444

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

1025-30

issue

12

eissn

0024-4201

issn

1558-9307

journal_volume

22

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Maternal dietary conjugated linoleic acid alters hepatic triacylglycerol and tissue fatty acids in hatched chicks.

    abstract::The effects of feeding CLA to hens on newly hatched chick hepatic and carcass lipid content, liver TAG accumulation, and FA incorporation in chick tissues such as liver, heart, brain, and adipose were studied. These tissues were selected owing to their respective roles in lipid assimilation (liver), as a major oxidati...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-005-1367-3

    authors: Cherian G,Ai W,Goeger MP

    更新日期:2005-02-01 00:00:00

  • Development of an LC-MS/MS method for the analysis of free sphingoid bases using 4-fluoro-7-nitrobenzofurazan (NBD-F).

    abstract::The molecular species of sphingoid bases were tagged with the fluorescent amino group reagent, 4-fluoro-7-nitrobenzofurazan (NBD-F). The NBD-sphingoid bases were analyzed by a highly selective and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) technique capable of relia...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-013-3871-6

    authors: Ishikawa T,Imai H,Maki KY

    更新日期:2014-03-01 00:00:00

  • Effects of essential fatty acid deficiency on prostaglandin synthesis and fatty acid composition in rat renal medulla.

    abstract::Studies are reported on the capacity of isolated rat renal papilla (inner medulla) to synthesize and release prostaglandin (PG) E from endogenous and exogenous precursor(s) during development of an essential fatty acid (EFA) deficiency in the rat. Weanling (21-day-old) male Sprague-Dawley rats were fed a fat-free diet...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533845

    authors: Dunham EW,Balasingam M,Privett OS,Nickell EC

    更新日期:1978-12-01 00:00:00

  • Triticale dried distillers' grain increases alpha-linolenic acid in subcutaneous fat of beef cattle fed oilseeds.

    abstract::This study investigated the effect of triticale dried distillers' grain with solubles (DDGS), flax (FS) and sunflower (SS) seed on growth and the fatty acid profile of subcutaneous (SQ) fat in individually housed steers (n = 15 per diet) fed ad libitum (DM basis); (1) control (CON) 90% barley grain + 10% barley silage...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-012-3720-z

    authors: He ML,Sultana H,Oba M,Kastelic JP,Dugan ME,McKinnon JJ,McAllister TA

    更新日期:2012-12-01 00:00:00

  • Effect of dietary vitamin E upon fluorescent compounds of the rat uterus.

    abstract::Several water soluble and organic solvent soluble fluorescent peaks were observed in extracts of uteri from vitamin E deficient or supplemented rats following Sephadex column chromatography and spectrophotofluorometric analysis. Levels of one of the organic and two of the water soluble fluorescent peaks were found to ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534725

    authors: Csallany AS,Ayaz KL,Menken BZ

    更新日期:1984-12-01 00:00:00

  • A new quantitative method for the analysis of monoacylglycerol isomers using(13)C nuclear magnetic resonance spectroscopy.

    abstract::Current methods for determining the regiochemistry of monoacylglycerols are lengthy, tedious and aggravated by the ready isomerization of 2-acyl-sn-glycerols. A new method employs a very rapid adsorption chromatography step in which isomerization is kept to a minimum, followed by formation of the isopropylidene deriva...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537348

    authors: Dawe RD,Wright JJ

    更新日期:1988-04-01 00:00:00

  • Effect of lecithin on jejunal absorption of micellar lipids in man and on their monomer activity in vitro.

    abstract::The effect of lecithin on jejunal absorption of fatty acids and octadecenoylglycerol was studied in healthy volunteers with a jejunal perfusion system which excluded pancreatic and biliary secretions from the test segment. Lecithin significantly reduced the absorption of oleic acid (P less than 0.05) and octadecenoylg...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533424

    authors: Ammon HV,Thomas PJ,Phillipis SF

    更新日期:1979-04-01 00:00:00

  • Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice.

    abstract::Previous research in rats and mice has suggested that gamma-linolenic acid (GLA) derived from borage oil (BO: 23% GLA) may be an appropriate source for increasing levels of long-chain n-6 FA in the developing brain. Recently, transgenic technology has made available a highly enriched GLA seed oil from the canola plant...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1048-2

    authors: Wainwright PE,Huang YS,DeMichele SJ,Xing H,Liu JW,Chuang LT,Biederman J

    更新日期:2003-02-01 00:00:00

  • Analysis of volatile fatty acids in biological specimens by capillary column gas chromatography.

    abstract::A method was developed to analyze and quantify volatile fatty acids (VFA) such as acetic, propionic, butyric, isobutyric, valeric and isovaleric acids in biological specimens. To obtain good sample transfer into the chromatographic system an organic solvent had to be used together with an aqueous milieu, thus improvin...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537302

    authors: Fleming SE,Traitler H,Koellreuter B

    更新日期:1987-03-01 00:00:00

  • Dietary CLA and DHA modify skin properties in mice.

    abstract::This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collag...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1105-x

    authors: Oikawa D,Nakanishi T,Nakamura Y,Takahashi Y,Yamamoto T,Shiba N,Tobisa M,Takagi T,Iwamoto H,Tachibana T,Furuse M

    更新日期:2003-06-01 00:00:00

  • Responses of MAC-T Cells to Inhibited Stearoyl-CoA Desaturase 1 during cis-9, trans-11 Conjugated Linoleic Acid Synthesis.

    abstract::Cis-9-conjugated, trans-11-conjugated linoleic acid (CLA) is known for its positive activities on human health. The synthesis of cis-9, trans-11 CLA in mammary glands is generally thought to be catalyzed by stearoyl-CoA desaturase 1 (SCD1), but this has not been rigorously established. In this study, we hypothesized t...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12077

    authors: Wang T,Lee H,Zhen Y

    更新日期:2018-06-01 00:00:00

  • Seasonal variations of lipid content and composition in Perna viridis.

    abstract::The total lipid content, composition of main lipid classes, composition of sterols and composition of fatty acids in the main glycerolipids of Perna viridis were analyzed through four seasons using TLC-FID and GLC. Mussel samples were collected during different seasons between 2003 and 2004 from Shengsi Island, Zhejia...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-007-3078-9

    authors: Li D,Zhang Y,Sinclair AJ

    更新日期:2007-08-01 00:00:00

  • Structural characterization of a "signature" phosphatidylethanolamine as the major 10-hydroxy stearic acid-containing lipid of Cryptosporidium parvum oocysts.

    abstract::A 10-hydroxy stearic acid-containing lipid from Cryptosporidium parvum was purified by thin-layer chromatography and analyzed by infrared spectroscopy, fast-atom bombardment mass spectrometry, 1H and 31P nuclear magnetic resonance spectroscopy, and was identified as phosphatidyl-ethanolamine. ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-997-0102-4

    authors: Schrum DP,Alugupalli S,Kelly ST,White DC,Fayer R

    更新日期:1997-07-01 00:00:00

  • Inhibition of LCAT in plasma from man and experimental animals by chlorpromazine.

    abstract::Chlorpromazine (CPZ), a major tranquilizer, was found to be a potent inhibitor of lecithin:cholesterol acyltransferase (LCAT, EC 2.3.1.43) in the plasma of normal man, rat, rabbit and dog in vitro. The inhibitory effect of CPZ reached 35-50% at 0.5 mM depending on species; dog plasma LCAT appeared to be somewhat more ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535035

    authors: Bell FP,Hubert EV

    更新日期:1981-11-01 00:00:00

  • Response of plasma lipids to dietary cholesterol and wine polyphenols in rats fed polyunsaturated fat diets.

    abstract::This experiment was designed to evaluate the effects of dietary red wine phenolic compounds (WP) and cholesterol on lipid oxidation and transport in rats. For 5 wk, weanling rats were fed polyunsaturated fat diets (n-6/n-3 = 6.4) supplemented or not supplemented with either 3 g/kg diet of cholesterol, 5 g/kg diet of W...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0610-2

    authors: Frémont L,Gozzelino MT,Linard A

    更新日期:2000-09-01 00:00:00

  • Lysophosphatidylcholine acyltransferase activity during experimental cholelithiasis.

    abstract::The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535337

    authors: Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

    更新日期:1981-10-01 00:00:00

  • Effects of ascorbate on membrane phospholipids and tocopherols of intact erythrocytes during peroxidation by t-butylhydroperoxide: comparison with effects of dithiothreitol.

    abstract::Peroxidation of intact human erythrocytes by t-butylhydroperoxide (tBHP)) was studied. By incubation of the erythrocytes with 1 mM tBHP, reduced glutathione (GSH) was exhausted within 1 min, and tocopherols (Toc) and phospholipids (PL) decreased to nearly their lowest levels (in this study) within 5 min. The rate of d...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-001-0668-x

    authors: Mawatari S,Murakami K

    更新日期:2001-01-01 00:00:00

  • Dyslipidemic diabetic serum increases lipid accumulation and expression of stearoyl-CoA desaturase in human macrophages.

    abstract::Type 2 diabetes and dyslipidemia are risk factors for cardiovascular disease. However, mechanisms by which hypertriglyceridemia influences atherogenesis remain unclear. We examined effects of dyslipidemic diabetic serum on macrophage lipid accumulation as a model of foam cell formation. Normal human macrophages were c...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-011-3578-5

    authors: Wong BX,Kyle RA,Myhill PC,Croft KD,Quinn CM,Jessup W,Yeap BB

    更新日期:2011-10-01 00:00:00

  • Epicoprostanol found in adipocere from five human autopsies.

    abstract::Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-997-0148-3

    authors: Adachi J,Ueno Y,Miwa A,Asano M,Nishimura A,Tatsuno Y

    更新日期:1997-11-01 00:00:00

  • Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease.

    abstract::Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palm...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537234

    authors: Rabinowitz JL,Ostermann L Jr,Bora FW,Staeffen J

    更新日期:1983-05-01 00:00:00

  • Interaction of rabbit lipoproteins and red blood cells with liposomes of egg yolk phospholipids.

    abstract::After intravenous injection of liposomes prepared from egg yolk phospholipids into rabbits, the phospholipids were readily assimilated by the lipoproteins, and there were increases in the circulating levels of cholesterol and phospholipids. The increases in cholesterol level were mainly due to increases of free choles...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536344

    authors: Mendez AJ,He JL,Huang HS,Wen SR,Hsia SL

    更新日期:1988-10-01 00:00:00

  • Suppression of cholesterogenesis by plant constituents: review of Wisconsin contributions to NC-167.

    abstract::In animals, non-sterol metabolites of the mevalonate pathway act independently from receptor-mediated cholesterol uptake in the multivalent feedback regulation of mevalonate biosynthesis. Studies leading to the isolation and characterization of plant-borne suppressors of mevalonate biosynthesis are reviewed. We propos...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534407

    authors: Qureshi AA,Burger WC,Peterson DM,Elson C

    更新日期:1985-11-01 00:00:00

  • Endurance training increases leptin expression in the retroperitoneal adipose tissue of rats fed with a high-sugar diet.

    abstract::The presence of leptin receptors in white adipose tissue (WAT) suggests a type of peripheral control during the development of obesity and other metabolic disorders. Both diet composition and exercise influence serum leptin; however, the effect of their combination on long-term WAT leptin metabolism is unknown. In thi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-013-3854-7

    authors: de Queiroz KB,Guimarães JB,Coimbra CC,Rodovalho GV,Carneiro CM,Evangelista EA,Guerra-Sá R

    更新日期:2014-01-01 00:00:00

  • Protective Effect of Unsaturated Fatty Acids on Palmitic Acid-Induced Toxicity in Skeletal Muscle Cells is not Mediated by PPARδ Activation.

    abstract::Unsaturated free fatty acids (FFA) are able to prevent deleterious effects of saturated FFA in skeletal muscle cells although the mechanisms involved are still not completely understood. FFA act as endogenous ligands of peroxisome proliferator-activated receptors (PPAR), transcription factors regulating the expression...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-4058-0

    authors: Tumova J,Malisova L,Andel M,Trnka J

    更新日期:2015-10-01 00:00:00

  • Correcting the effects of -20 °C storage and aliquot size on erythrocyte fatty acid content in the Women's Health Initiative.

    abstract::Red blood cell (RBC) fatty acid (FA) patterns have been shown to predict risk for cardiovascular and other chronic diseases. As part of a project analyzing RBC samples from the Women's Health Initiative Memory Study (WHIMS) we observed implausibly low levels of highly unsaturated fatty acids (HUFA) suggestive of degra...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-012-3693-y

    authors: Pottala JV,Espeland MA,Polreis J,Robinson J,Harris WS

    更新日期:2012-09-01 00:00:00

  • Palmitic acid and oleic acid differentially regulate choline transporter-like 1 levels and glycerolipid metabolism in skeletal muscle cells.

    abstract::Choline is an essential nutrient required for the biosynthesis of membrane lipid phosphatidylcholine (PtdCho). Here we elucidate the mechanism of how palmitic acid (PAM) and oleic acid (OLA) regulate choline transporter-like protein 1 (CTL1/SLC44A1) function. We evaluated the mechanism of extracellular and intracellul...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-014-3925-4

    authors: Schenkel LC,Bakovic M

    更新日期:2014-08-01 00:00:00

  • Quantitative measurement of prostaglandins E2 and E2 by selected ion monitoring.

    abstract::A method for the simultaneous quantitative analysis of prostaglandin E2 (PGE2) and PGE3 is described. The PG were analyzed by selected ion monitoring as the methyl ester-TMS ether derivatives of PGB2 and PGB3, respectively. The internal standard for the quantification of both species was [3,3,4,4-2H4]PGE2. A linear re...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535360

    authors: Ferretti A,Flanagan VP,Roman JM

    更新日期:1982-11-01 00:00:00

  • Novel lipidic enaminones from a C18 keto-allenic ester.

    abstract::Primary amines (ammonia, methyl, propyl, octyl, octadecyl, phenyl, benzyl, phenethyl) including methyl esters of amino acids (glycine, DL-alanine, L-valine, L-leucine, L-tyrosine, and L-methionine), and secondary amines (dimethyl, diethyl, dipropyl, diisopropyl, dioctyl, and diphenyl) attack regiospecifically the cent...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0629-4

    authors: Jie MS,Lau MM

    更新日期:2000-10-01 00:00:00

  • The biosynthesis of oxylipins of linoleic and arachidonic acids by the sewage fungus Leptomitus lacteus, including the identification of 8R-Hydroxy-9Z,12Z-octadecadienoic acid.

    abstract::When the sewage fungus Leptomitus lacteus was grown in liquid culture aerobically and then transferred to medium containing long-chain fatty acids, it produced a number of oxygenated fatty acids. From linoleic acid (18:2n-6), the major metabolite produced was R-8-hydroxy-9Z,12Z-octadecadienoic acid (8R-HODE), with add...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0490-5

    authors: Fox SR,Akpinar A,Prabhune AA,Friend J,Ratledge C

    更新日期:2000-01-01 00:00:00

  • Effect of dietary linoleic acid content on the distribution of triacylglycerol molecular species in rat adipose tissue.

    abstract::The present study examined the effect of varying dietary linoleate intake (0.01, 0.24, 2.4, 24, 80 or 160 g/kg diet) for 24 weeks on the distribution of triacylglycerol (TG) molecular species in rat epididymal adipose tissue. Adipose TG fractions were purified by thin-layer chromatography and separated into different ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536030

    authors: Huang YS,Lin X,Smith RS,Redden PR,Jenkins DK,Horrobin DF

    更新日期:1992-09-01 00:00:00