Abstract:
:Current methods for determining the regiochemistry of monoacylglycerols are lengthy, tedious and aggravated by the ready isomerization of 2-acyl-sn-glycerols. A new method employs a very rapid adsorption chromatography step in which isomerization is kept to a minimum, followed by formation of the isopropylidene derivatives using mild procedures. These cyclic derivatives of 1- and 3-acyl-sn-glycerols and 2-acyl-sn-glycerols are stable thermally and display certain characteristic(13)C NMR resonances. Integration of these resonances yields directly the proportion of monoacylglycerol isomers in the mixture. The method was applied to the analysis of monoacylglycerols produced by enzymatic hydrolysis of synthetic and naturally occurring triacylglycerols.
journal_name
Lipidsjournal_title
Lipidsauthors
Dawe RD,Wright JJdoi
10.1007/BF02537348subject
Has Abstractpub_date
1988-04-01 00:00:00pages
355-8issue
4eissn
0024-4201issn
1558-9307pii
10.1007/BF02537348journal_volume
23pub_type
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