Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells.

abstract：:Rats were fed either a high alpha-linolenate diet or a high linoleate diet from weaning to 4 mon of age. Soybean oil was used as a control. Phospholipid compositions of erythrocytes from the three dietary groups were not significantly different. However, the difference in the alpha-linolenate (18:3n-3)/linoleate (18:2...

journal_title：Lipids

authors： Sakai K,Okuyama H,Kon K,Maeda N,Sekiya M,Shiga T,Reitz RC

更新日期：1990-12-01 00:00:00

abstract：:Lysophosphatidic acid (lysoPtdOH), a lysophospholipid mediator, exerts diverse physiological effects, including angiogenesis, through its specific G-protein-coupled receptors. Previously, we showed that unfertilized hen egg white contains polyunsaturated fatty acid-rich lysoPtdOH and lysophospholipase D (lysoPLD). Her...

journal_title：Lipids

authors： Morishige J,Uto Y,Hori H,Satouchi K,Yoshiomoto T,Tokumura A

更新日期：2013-03-01 00:00:00

abstract：:Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance. ...

journal_title：Lipids

authors： Smith LL

更新日期：1996-05-01 00:00:00

abstract：:Fatty acid synthetase purified (20 times) from lactating bovine mammary tissue had an approximate mot wt of 485,000. The enzyme had a high content of acidic and hydrophobic amino acid residues; 62±4 sulhydryl groups and one 4' phosphopantetheine residue/mole of enzyme. The enzyme was relatively stable when stored (3 m...

journal_title：Lipids

authors： Kinsella JE,Bruns D,Infante JP

更新日期：1975-04-01 00:00:00

abstract：:If an increased consumption of alpha-linolenic acid (ALA) is to be promoted in parallel with that of n-3 long-chain-rich food, it is necessary to consider to what extent dietary ALA can be absorbed, transported, stored, and converted into long-chain derivatives. We investigated these processes in male hamsters, over a...

journal_title：Lipids

authors： Morise A,Combe N,Boué C,Legrand P,Catheline D,Delplanque B,Fénart E,Weill P,Hermier D

更新日期：2004-04-01 00:00:00

abstract：:Two per thousand pregnant women have hyperthyroidism (HT), and although the symptoms are attenuated during pregnancy, they rebound after delivery, affecting infant development. To examine the effects of hyperthyroidism on lactation, we studied lipid metabolism in maternal mammary glands and livers of hyperthyroid rats...

journal_title：Lipids

authors： Varas SM,Jahn GA,Giménez MS

更新日期：2001-08-01 00:00:00

abstract：:Oxidized LDL (oxLDL) has been shown to activate the sphingomyelinase pathway producing ceramide in vascular smooth muscle cells. Therefore ceramide, which is a biologically active lipid causing apoptosis in a variety of cells, may be involved in the apoptotic action of oxLDL. In this study, we examined whether cholest...

journal_title：Lipids

authors： Ichi I,Takashima Y,Adachi N,Nakahara K,Kamikawa C,Harada-Shiba M,Kojo S

更新日期：2007-10-01 00:00:00

abstract：:Glucose-sensitive liposomes were prepared by incorporating hydrophobically modified glucose oxidase (EC 1.1.3.4.) into the liposomal bilayer of dioleoylphosphatidylethanolamine and cholesteryl hemisuccinate. For the release test, calcein, a fluorescence marker, was entrapped in the liposomes. The liposomes were stable...

journal_title：Lipids

authors： Jo SM,Lee HY,Kim JC

更新日期：2008-10-01 00:00:00

abstract：:This study reports the cloning, functional characterization, tissue expression, and nutritional regulation of a delta6 fatty acyl desaturase of Atlantic cod (Gadus morhua). PCR primers were designed based on the sequences of conserved motifs in available fish desaturases and used to isolate a cDNA fragment from cod li...

journal_title：Lipids

authors： Tocher DR,Zheng X,Schlechtriem C,Hastings N,Dick JR,Teale AJ

更新日期：2006-11-01 00:00:00

abstract：:The antioxidant effects of natural estrogens (estrone, E1; 17 beta-estradiol), synthetic estrogens (17 alpha-ethynylestradiol, EE2; mestranol, MES; diethylstilbestrol, DES) and catecholestrogens (2-hydroxyestradiol; 4-hydroxyestradiol, 4-OHE2) on lipid peroxidation induced by different means in rat liver microsomes we...

journal_title：Lipids

authors： Lacort M,Leal AM,Liza M,Martín C,Martínez R,Ruiz-Larrea MB

更新日期：1995-02-01 00:00:00

abstract：:A fluorescent radiolabeled triacylglycerol has been synthesized by using a fluorescent fatty acid (pyrene decanoic acid) and a radiolabeled oleic acid. This analog of the natural substrate, 1(3)pyrene decanoic-2,3 (1,2)-dioleoyl-sn-glycerol, has been tested as substrate for determining lipoprotein lipase and hepatic t...

journal_title：Lipids

authors： Dousset N,Negre A,Salvayre R,Rogalle P,Dang QQ,Douste-Blazy L

更新日期：1988-06-01 00:00:00

abstract：:The activity of pyruvate dehydrogenase from freshly isolated mitochondria was shown to be dependent upon the nutritional and metabolic state of the animal prior to sacrifice, such that mitochondria from the livers of 48 hr starved, diabetic, or high fat fed rats had lower enzyme activity than normal, chow fed rats. Th...

journal_title：Lipids

authors： Mapes JP,Harris RA

更新日期：1975-12-01 00:00:00

abstract：:In experiments on dogs, i.v. administration of platelet-activating factor (PAF) (500 ng/kg) was shown to induce hypotension which, apart from decreased myocardial contractility, was characterized by blood pooling in veins (82.6 +/- 6.8 mL/kg). This was accompanied by restriction of venous return to the heart and reduc...

journal_title：Lipids

authors： Sagach VF,Dmitrieva AV,Braquet P

更新日期：1991-12-01 00:00:00

abstract：:A group of homologous, nonmethylene-interrupted dienoic fatty acids (NMID) recently reported in oysters has been found in several other shellfish species and also in other marine phyla. The distribution of most other "normal" fatty acids among several species of shellfish is basically similar but mantle lipids from tw...

journal_title：Lipids

authors： Paradis M,Ackman RG

更新日期：1977-02-01 00:00:00

abstract：:By means of cellulose acetate electrophoresis and measurement of radio-activity, lipoproteins (d less than or equal to 1,006) of lymph collected from rats fed a diet containing fats added to labeled fatty acids for 20-24 hr, have been separated into two kinds differing in their size. Fats with different saturated and ...

journal_title：Lipids

authors： Boquillon M,Paris R,Clement J

更新日期：1977-06-01 00:00:00

abstract：:Fatty acid alpha-hydroxylase from Sphingomonas paucimobilis is an unusual cytochrome P450 enzyme that hydroxylates the alpha-carbon of fatty acids in the presence of H2O2. Herein, we describe our investigation concerning the utilization of various substrates and the optical configuration of the alpha-hydroxyl product ...

journal_title：Lipids

authors： Matsunaga I,Sumimoto T,Ueda A,Kusunose E,Ichihara K

更新日期：2000-04-01 00:00:00

abstract：:We have developed cultures of smooth muscle cells (SMC) isolated from arterial hypercholesterolemic chicks (cholesterol-SMC). These cultures are suitable for the study at the molecular level of the changes in arterial SMC induced by a cholesterol diet. By using a strong dose of cholesterol (5%) for 10 d, we obtained v...

journal_title：Lipids

authors： Carazo A,Alejandre J,Diaz R,Ríos A,Castillo M,Linares A

更新日期：1998-02-01 00:00:00

abstract：:Developing rat brain has the capacity for either delta 9 or delta 6 desaturation of fatty acids. In liver, evidence supports the existence of separate enzymes for each reaction, but it is not known whether in brain delta 9 or delta 6 desaturation of saturated fatty acids involves distinct enzymes. We have used fatty a...

journal_title：Lipids

authors： Cook HW

更新日期：1979-09-01 00:00:00

abstract：:In guinea pigs, total plasma cholesterol concentrations increased above the control values after single intravenous injections and after 3 days of continuous subcutaneous administration of neurotensin (NT). A high dose of NT (125 pmol/100 g body weight) induced tachycardia and severe respiratory distress; the lowest d...

journal_title：Lipids

authors： Peric-Golia L,Gardner CF,Wilson DE,Peric-Golia M

更新日期：1984-10-01 00:00:00

abstract：:The present study examined the effect of varying dietary linoleate intake (0.01, 0.24, 2.4, 24, 80 or 160 g/kg diet) for 24 weeks on the distribution of triacylglycerol (TG) molecular species in rat epididymal adipose tissue. Adipose TG fractions were purified by thin-layer chromatography and separated into different ...

journal_title：Lipids

authors： Huang YS,Lin X,Smith RS,Redden PR,Jenkins DK,Horrobin DF

更新日期：1992-09-01 00:00:00

abstract：:The present study determined alpha-tocopherol mass transfer from an alpha-tocopherol-rich emulsion to LDL and HDL, and assessed the potential of different mechanisms to modulate alpha-tocopherol transfers. Emulsion particles rich in alpha-tocopherol were incubated in vitro with physiological concentrations of LDL or H...

journal_title：Lipids

authors： Hacquebard M,Vandenbranden M,Malaisse WJ,Ruysschaert JM,Deckelbaum RJ,Carpentier YA

更新日期：2008-07-01 00:00:00

abstract：:Although hypocholesterolemia is a reported finding in sickle cell disease (SCD), low-density lipoprotein (LDL)/high-density lipoprotein (HDL) subfractions and HDL-associated enzymes have not been determined in SCD patients. Blood was collected from 38 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients who had...

journal_title：Lipids

authors： Ozturk OH,Can Y,Yonden Z,Motor S,Oktay G,Kaya H,Aslan M

更新日期：2013-12-01 00:00:00

abstract：:Olive oil, a major component of the Mediterranean diet, has been associated in some small clinical trials and cross-sectional studies with a reduction in blood pressure. The objective of this study was to assess the association of olive oil consumption with the incidence of hypertension in an epidemiologic cohort, the...

journal_title：Lipids

authors： Alonso A,Martínez-González MA

更新日期：2004-12-01 00:00:00

abstract：:Mice exposed to cold rely upon brown adipose tissue (BAT)-mediated nonshivering thermogenesis to generate body heat using dietary glucose and lipids from the liver and white adipose tissue. In this report, we investigate how cold exposure affects the PI3 K/Akt signaling cascade and the expression of genes involved in ...

journal_title：Lipids

authors： Deiuliis JA,Liu LF,Belury MA,Rim JS,Shin S,Lee K

更新日期：2010-06-01 00:00:00

abstract：:Dysregulation of adipokines is a hallmark of obesity. Polyunsaturated fatty acids in fish oil may exert anti-inflammatory effects on adipose tissue mitigating the dysregulation of adipokines thereby preventing obesity. This study investigated the effects of high-fat diets containing different amounts of n3 polyunsatur...

journal_title：Lipids

authors： Sundaram S,Bukowski MR,Lie WR,Picklo MJ,Yan L

更新日期：2016-05-01 00:00:00

abstract：:The catfish, Ictalurus punctatus, is an important model for studying the biochemical mechanisms of taste at the peripheral level. The type, amount and metabolic activity of the lipids within this tissue play important roles in taste transduction by forming the matrix in which the receptors for taste stimuli are imbedd...

journal_title：Lipids

authors： Rabinowitz JL,Huque T,Brand JG,Bayley DL

更新日期：1990-04-01 00:00:00

abstract：:Fecal bile acid and neutral sterol patterns were studied in eight healthy adult volunteers who were challenged with Vibrio cholerae classical Ogawa 395 strain in the course of vaccine development studies. Bacterial 7 alpha-dehydroxylation of cholic and chenodeoxycholic acids was not altered during experimentally induc...

journal_title：Lipids

authors： Huang CT,Levine MM,Daoud GS,Nalin DR,Nichols BL

更新日期：1982-09-01 00:00:00

abstract：:Recent reports show that a fatty meal can substantially increase the concentration of oxidized lipids in low density lipoprotein (LDL). Knowing the LDL-specific antioxidant effects of high density lipoprotein (HDL), we aimed to investigate whether HDL can modify the postprandial oxidative stress after a fatty meal. Su...

journal_title：Lipids

authors： Tiainen S,Ahotupa M,Ylinen P,Vasankari T

更新日期：2014-12-01 00:00:00

abstract：:Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methylcis,cis,cis-5,8,11-eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative...

journal_title：Lipids

authors： Ghosh A,Koley M,Dutta J

更新日期：1982-04-01 00:00:00

abstract：:Chemical ionization (CI) mass spectra of various natural and synthetic steroids have been studied using methane, isobutane, ammonia, trideuterioammonia and hydroxy anion as reagent gases. The CI spectra of steroids give simple and well characterized ions, which provide information about molicular weight as well as fun...

journal_title：Lipids

authors： Lin YY

更新日期：1980-09-01 00:00:00