Abstract:
:Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palmitate and [14C]stearate in approximately equal yields as those obtained from "controls." No [14C]octanate was formed in any of the palmar-fat preparations. The lipids and fatty acid analysis revealed differences: (a) DDPF specimens were richer in free fatty acids, methyl esters of fatty acids and free-cholesterol than specimens of controls. (b) DDPF specimens contained less phospholipids. (c) DDPF specimens showed a significantly higher content of octanoate and other short-chain fatty acids than specimens of controls. The above findings are not incompatible with the results expected if some mild hypoxia occurred in DDPF; this has been suggested in the statistical correlations observed for this disease and alcoholism with liver involvement.
journal_name
Lipidsjournal_title
Lipidsauthors
Rabinowitz JL,Ostermann L Jr,Bora FW,Staeffen Jdoi
10.1007/BF02537234subject
Has Abstractpub_date
1983-05-01 00:00:00pages
371-4issue
5eissn
0024-4201issn
1558-9307journal_volume
18pub_type
杂志文章相关文献
LIPIDS文献大全abstract::A fast and efficient shotgun lipidomics strategy was applied to analyze phospholipids (PL) in the oyster Crassostrea plicatula, including 29 species of phosphatidylcholine (PtdCho), 23 species of phosphatidylethanolamine (PtdEtn), 11 species of phosphatidylserine (PtdSer), 6 species of phosphatidylinositol (PtdIns), a...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-017-4305-7
更新日期:2017-12-01 00:00:00
abstract::Cholesterol absorption is frequently determined using the plasma dual stable-isotope ratio method (PDSIRM). However, this method involves intravenous injection of stable-isotope-labeled cholesterol with simultaneous oral administration of differently labeled cholesterol, which results in high study costs and involves ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-004-1206-6
更新日期:2004-01-01 00:00:00
abstract::Lipid-enriched diets have been related to a high cancer incidence in experimental animals for many years, and more recently, to assorted defects on the immune response. We investigated the effect of incubating human or murine (C3H/HEJ) lymphocytes with saturated (16:0) and unsaturated (18:1, 18:2, 18:3, 20:4) fatty ac...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534659
更新日期:1982-10-01 00:00:00
abstract::By means of cellulose acetate electrophoresis and measurement of radio-activity, lipoproteins (d less than or equal to 1,006) of lymph collected from rats fed a diet containing fats added to labeled fatty acids for 20-24 hr, have been separated into two kinds differing in their size. Fats with different saturated and ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535449
更新日期:1977-06-01 00:00:00
abstract::The purpose of the present study was to investigate the physiological control of the main regulatory enzymes of cholesterol metabolism in isolated enterocytes obtained from chick duodenum, jejunum and ileum. Cholesterol feeding resulted in an inhibition of 3-hydroxy-3-methyl-glutaryl-CoA reductase and mevalonate 5-pyr...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536087
更新日期:1993-06-01 00:00:00
abstract::Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance. ...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02522641
更新日期:1996-05-01 00:00:00
abstract::All fatty acids have important functions, but the term "essential" is applied only to those polyunsaturated fatty acids (PUFA) that are necessary for good health and cannot be completely synthesized in the body. The need for arachidonic acid, which is utilized for eicosanoid synthesis and is a constituent of membrane ...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02562220
更新日期:1999-01-01 00:00:00
abstract::For four weeks, groups of eight male and eight female F344/N rats were fed diets containing 15.5, 20, 30 or 40% of energy (en%) as fat. The fat was composed of corn oil and beef tallow with 9 en% from linoleate in all diets. Females had greater mean hepatic alpha-tocopherol levels, whereas males had greater plasma alp...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535861
更新日期:1992-11-01 00:00:00
abstract::Linoleic acid was efficiently converted into the two major components of conjugated linoleic acid, 9Z,11E-octadecadienoic (1a) and 10E,12Z-octadecadienoic acid (1b) using either the superbase (n-butyllithium/potassium tert-butoxide) or by simply refluxing with KOH in 1-butanol. In turn, 1a and 1b were separated from e...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-999-0436-y
更新日期:1999-08-01 00:00:00
abstract::Plant sterols were found by gas liquid chromatography in the sterols of five species of aquatic vertebrates; mackerel (Scomber japonicus), rainbow trout (Salmo gairdnerii), smelt (Osmerus dentex), sardine (Sardinops melanosticta) and chimera (Chimera phantasma). The sterols of chimera liver, sardine flesh and sardine ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533558
更新日期:1979-01-01 00:00:00
abstract::A protocol using a dry column method was modified for the extraction of total lipids and the simultaneous separation and quantitation of neutral and polar lipids in human milk. The triacylglycerol, cholesterol, phospholipid and vitamin E contents of the lipid extracts were determined and compared with lipids extracted...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535216
更新日期:1989-08-01 00:00:00
abstract::Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-997-0148-3
更新日期:1997-11-01 00:00:00
abstract::Tissue and blood fatty acid compositions are used as biological markers of fatty acid intakes to improve dietary assessments. These approaches are invasive and not well accepted, particularly in infants and young children. We developed a sensitive method for the analysis of fatty acids in cheek cell glycerophospholipi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-011-3576-7
更新日期:2011-10-01 00:00:00
abstract::Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects consuming a low fat (20% of calories) diet consisting of fatty acids...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535293
更新日期:1988-02-01 00:00:00
abstract::Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted five- or six-carbon-membered ring structures. Some earlier studies have suggested that some of these molecules could be metabolized and detoxified, but so far, nei...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-3997-9
更新日期:2015-04-01 00:00:00
abstract::The content and positional distribution of CLA in TAG fractions of lamb tissues was examined with either preformed CLA or the linoleic acid precursor of CLA in the diet as experimental treatments. The CLA content of phospholipid (PL) from these tissues was also examined. Thirteen lambs were randomized to the following...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-002-0939-6
更新日期:2002-06-01 00:00:00
abstract::The term "conjugated linoleic acid" (CLA) refers to a group of positional and geometric isomers that are derived from linoleic acid and are found primarily in meat and milk products from ruminant animals. Due to the array of putative benefits associated with various forms of CLA, there has been recent interest in supp...
journal_title:Lipids
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11745-007-3087-8
更新日期:2007-08-01 00:00:00
abstract::Ceramides are a family of signalling lipids with diverse physiological functions that include pro-differentiative and pro-apoptotic signalling. Ceramides and their derivatives are major constituents of myelin, maintaining neuronal conductivity. Ceramides are synthesized by ceramide synthases, of which there are six is...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3969-5
更新日期:2015-01-01 00:00:00
abstract::Eighteen-month-old Nebraska strain minipigs were fed diets containing 2% cholesterol and 20% corn oil, lard, or coconut oil for 12 to 18 months. Concentrations of serum total lipid, total cholesterol, and total phospholipid increased 200 to 300% with each diet. Changes in serum concentrations of Sf 20+ and Sf 0-20 lip...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533395
更新日期:1978-03-01 00:00:00
abstract::Male and female weanling rats that were born to dams fed a diet low in linolenic acid received diets of 15% lipids by weight containing 45% elaidic acid (as trielaidin) and 8.5% or 0.1% linolenic acid for 10 weeks. Four other groups, in which palmitic or oleic acid replaced elaidic acid in the diet, served as controls...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536444
更新日期:1987-12-01 00:00:00
abstract::The effects of feeding CLA to hens on newly hatched chick hepatic and carcass lipid content, liver TAG accumulation, and FA incorporation in chick tissues such as liver, heart, brain, and adipose were studied. These tissues were selected owing to their respective roles in lipid assimilation (liver), as a major oxidati...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-005-1367-3
更新日期:2005-02-01 00:00:00
abstract::Red blood cell (RBC) fatty acid (FA) patterns have been shown to predict risk for cardiovascular and other chronic diseases. As part of a project analyzing RBC samples from the Women's Health Initiative Memory Study (WHIMS) we observed implausibly low levels of highly unsaturated fatty acids (HUFA) suggestive of degra...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-012-3693-y
更新日期:2012-09-01 00:00:00
abstract::Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methylcis,cis,cis-5,8,11-eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534947
更新日期:1982-04-01 00:00:00
abstract::The uptake of lipid from the yolk by the yolk sac membrane of the chick embryo is accompanied by the rapid esterification of a large proportion of the yolk cholesterol. This could arise from enhanced acyl-CoA:cholesterol acyltransferase (ACAT) activity and/or inhibition of cholesteryl ester hydrolase (CEH) activity. T...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536056
更新日期:1993-07-01 00:00:00
abstract::Decreased triacylglycerol synthesis within hepatocytes due to decreased diacylglycerol acyltransferase (DGAT) activity has been suggested to be an important mechanism by which diets rich in fish oil lower plasma triacylglycerol levels. New findings suggest that eicosapentaenoic acid (EPA), and not docosahexaenoic acid...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-999-0445-x
更新日期:1999-09-01 00:00:00
abstract::The presence of leptin receptors in white adipose tissue (WAT) suggests a type of peripheral control during the development of obesity and other metabolic disorders. Both diet composition and exercise influence serum leptin; however, the effect of their combination on long-term WAT leptin metabolism is unknown. In thi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3854-7
更新日期:2014-01-01 00:00:00
abstract::The ganglioside and neutral glycosphingolipid composition of adult monkey small and large intestinal mucosa were characterized and compared. GM3, GM2 and GD1A were found to be the principal gangliosides in each of these tissues. Dihexosylceramide was the major neutral glycosphingolipid of both organs. The total conten...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534429
更新日期:1986-02-01 00:00:00
abstract::The degradation of exogenous radioactively labeled fatty acids by 5-day-old barley shoots was examined. [1-(14)C] Linoleic acid was observed to be degraded 7 times faster than [1-(14)C] oleic acid and 5 times faster than [1-(14)C] palmitic acid. The pathway of degradation was determined by identifying the water-solubl...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534483
更新日期:1984-07-01 00:00:00
abstract::We have investigated the regulation of cholesterol synthesis in isolated human small intestine epithelial cells (enterocytes). It was established that the amount of cholesterol synthesized increased linearly with the incubation time and the number of cells in the incubation mixture; the synthesis was suppressed by 7-k...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535408
更新日期:1986-12-01 00:00:00
abstract::After two months feeding either an (n-3) or an (n-6) fatty acid-rich diet, two groups of trout were switched to the (n-6) or the (n-3) fatty acid-rich diet, respectively. Half of each group was treated with 0.03% 5,8,11,14-eicosatetraynoic acid (ETYA) in the diet. Liver and intestinal brush border membrane lipids were...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536450
更新日期:1987-12-01 00:00:00