Distribution of glycosphingolipids of monkey small and large intestinal mucosa.

Abstract:

:The ganglioside and neutral glycosphingolipid composition of adult monkey small and large intestinal mucosa were characterized and compared. GM3, GM2 and GD1A were found to be the principal gangliosides in each of these tissues. Dihexosylceramide was the major neutral glycosphingolipid of both organs. The total content of gangliosides and neutral glycolipids/ceramide, however, was ca. four-fold and two-fold higher, respectively, in small intestinal than colonic mucosa. While all glycosphingolipids examined contained hydroxy and nonhydroxy fatty acids, the former fatty acids accounted for 60-90% of the total fatty acids in both organs. Sphingosine was the predominant long chain base of ceramide, mono-, di-, tri- and tetrahexosylceramide, whereas phytosphingosine was the major base of GM3 in both tissues. The results of these studies demonstrate that while many similarities of monkey small and large intestinal glycosphingolipids exist, qualitative and quantitative differences are present along the length of the monkey gut. These differences may be at least partially responsible for certain of the well-recognized variations in normal physiological and pathological processes that occur in these organs.

journal_name

Lipids

journal_title

Lipids

authors

Dahiya R,Brown MD,Brasitus TA

doi

10.1007/BF02534429

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

107-11

issue

2

eissn

0024-4201

issn

1558-9307

journal_volume

21

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Effects of fish oil, corn oil and lard diets on lipid peroxidation status and glutathione peroxidase activities in rat heart.

    abstract::In this study, we investigated the effect of various types of fats on heart lipid peroxidation status and on blood lipid parameters. Rats were fed either a low-fat diet (2.2% lard plus 2.2% corn oil), a corn oil diet (17%), a salmon oil diet (12.5%) supplemented with 4.5% corn oil, or a lard diet (15%) supplemented wi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535232

    authors: Nalbone G,Leonardi J,Termine E,Portugal H,Lechene P,Pauli AM,Lafont H

    更新日期:1989-03-01 00:00:00

  • sn-position determination of phospholipid-linked fatty acids derived from erythrocytes by liquid chromatography electrospray ionization ion-trap mass spectrometry.

    abstract::The sn-position of FA in membrane lipids has an influence on the physiological function of cells, is predictive for diseases, and therefore is useful for diagnostics. The current study compares the compositions of acyl chain substituents in the sn-1 and sn-2 positions of the glycerol backbones of phospholipids derived...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-005-1377-1

    authors: Beermann C,Möbius M,Winterling N,Schmitt JJ,Boehm G

    更新日期:2005-02-01 00:00:00

  • Mechanisms of linoleic acid uptake by rabbit small intestinal brush border membrane vesicles.

    abstract::We examined the initial transport of a long-chain unsaturated fatty acid, linoleic acid, by brush border membrane vesicles isolated from rabbit small intestine. This preparation allowed us to examine the transport of linoleic acid across the brush border membrane without the effect of the unstirred water layer or cyto...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535264

    authors: Ling KY,Lee HY,Hollander D

    更新日期:1989-01-01 00:00:00

  • Proteolytic susceptibility of platelet low density lipoprotein receptor.

    abstract::In order to further characterize low density lipoprotein (LDL)-platelet interaction, we investigated the effect of protease pretreatment of human platelets on the subsequent binding of iodinated LDL (125I-LDL). Our results showed that the platelet LDL receptor had a proteolytic susceptibility different from that of bo...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537484

    authors: Pedreño J,Fernández R

    更新日期:1995-10-01 00:00:00

  • Analysis of conjugated bile acids by high performance liquid chromatography and mass spectrometry.

    abstract::Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534697

    authors: Mingrone G,Greco AV,Boniforti L,Passi S

    更新日期:1983-01-01 00:00:00

  • Arachidonic acid: Occurrence in the reproductive tract of the male house cricket (Acheta domesticus) and field cricket (Gryllus spp.).

    abstract::Reproductive tissues from male house and field crickets were investigated for the presence of arachidonic acid. Arachidonic acid was identified by retention behavior on 3 gas liquid chromatographic column systems-SE-30, OV 225, and Silar 10C-and by gas liquid/positive ion chemical ionization mass spectrometry. Arachid...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534928

    authors: Worthington RE,Brady UE,Thean JE,Wilson DM

    更新日期:1981-01-01 00:00:00

  • Conjugated linoleic acids (CLA) as precursors of a distinct family of PUFA.

    abstract::One of the possibilities for distinct actions of c9,t11- and the t10,c12-conjugated linoleic acid (CLA) isomers may be at the level of metabolism since the conjugated diene structure gives to CLA isomers and their metabolites a distinct pattern of incorporation into the lipid fraction and metabolism. In fact, CLA appe...

    journal_title:Lipids

    pub_type: 杂志文章,评审

    doi:10.1007/s11745-004-1341-0

    authors: Banni S,Petroni A,Blasevich M,Carta G,Cordeddu L,Murru E,Melis MP,Mahon A,Belury MA

    更新日期:2004-11-01 00:00:00

  • Dietary guar gum reduces lymph flow and diminishes lipid transport in thoracic duct-cannulated rats.

    abstract::Guar gum has a well-recognized hypolipidemic effect. This effect is thought to be due to the physicochemical properties of guar gum, which may cause changes in adsorption of lipids or the viscosity of the intestinal contents. Guar gum is a non-specific absorption inhibitor of any type of lipid-soluble compound. Perman...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-011-3570-0

    authors: Shirouchi B,Kawamura S,Matsuoka R,Baba S,Nagata K,Shiratake S,Tomoyori H,Imaizumi K,Sato M

    更新日期:2011-08-01 00:00:00

  • 2-Methoxylated FA Display Unusual Antibacterial Activity Towards Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (CIMRSA) and Escherichia coli.

    abstract::The naturally occurring (6Z)-(±)-2-methoxy-6-hexadecenoic acid (1) and (6Z)-(±)-2-methoxy-6-octadecenoic acid (2) were synthesized in 7-8 steps with 38 and 13% overall yields, respectively, by using an acetylide coupling approach, which made it possible to obtain a 100% cis-stereochemistry for the double bonds. In a s...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-017-4262-1

    authors: Carballeira NM,Montano N,Morales C,Mooney J,Torres X,Díaz D,Sanabria-Rios DJ

    更新日期:2017-06-01 00:00:00

  • Paraoxonase 1 activity in chylomicrons and VLDL: the effect of type 2 diabetes and meals rich in saturated fat and oleic acid.

    abstract::Paraoxonase 1 (PON 1) has antioxidant and cardioprotective properties and is abnormally low in type 2 diabetic serum. This study aimed to determine the effect of type 2 diabetes and meals rich in saturated fat and oleic acid on PON1 activity in chylomicrons and very low density lipoproteins (VLDL). PON1 arylesterase a...

    journal_title:Lipids

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s11745-011-3640-3

    authors: Manning PJ,Jong SA,Ryalls AR,Sutherland WH

    更新日期:2012-03-01 00:00:00

  • Cholesteryl esterase activities in ventricles, isolated heart cells and aorta of the rat.

    abstract::Cholesteryl esterase activities were determined in homogenates of rat heart (ventricles), isolated, calcium-tolerant, cardiac myocytes and aortic tissue and were compared with acid and neutral triglyceride lipase activities in these fractions. Using cholesteryl oleate/phosphatidylcholine/taurocholate emulsions and dig...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534862

    authors: Stam H,Broekhoven-Schokker S,Schoonderwoerd K,Hülsmann WC

    更新日期:1987-02-01 00:00:00

  • Sphingomyelin metabolism is linked to salt transport in the gills of euryhaline fish.

    abstract::By in vivo and in vitro studies of L-(3-3H)serine and [9,10(n)-3H]palmitic acid incorporation into phospholipids, we show a change in the renewal of the ceramide moiety of sphingomyelin in the gills of euryhaline fish (sea bass and eels) when the animals were subjected to abrupt alterations in environmental salinity. ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02522924

    authors: el Babili M,Brichon G,Zwingelstein G

    更新日期:1996-04-01 00:00:00

  • Evaluation of apolipoprotein A-I kinetics in rabbits in vivo using in situ and exogenous radioiodination methods.

    abstract::The kinetics of in vivo clearance of apolipoprotein (apo) A-I radioiodinated by the iodine monochloride (ICI) method of McFarlane [McFarlane, A.S. (1958) Efficient Trace-Labelling of Proteins with Iodine, Nature 182, 53] as modified by Bilheimer and co-workers [Bilheimer, D.W., Eisenberg, S., and Levy, R.I. (1972) The...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1053-5

    authors: Zhang B,Shimoji E,Tanaka H,Saku K

    更新日期:2003-03-01 00:00:00

  • Hydrocarbon chain distribution of ether phospholipids of the ascidian Halocynthia roretzi and the sea urchin Strongylocentrotus intermedius.

    abstract::The contents and compositions of the 1-O-alk-1'-enyl-2-acyl, 1-O-alkyl-2-acyl, and 1,2-diacyl glycerophospholipids in the muscle and viscera of the ascidian Halocynthia roretzi, and of the gonad of the sea urchin Strongylocentrotus intermedius, which are eaten to some extent in Alaska and in Asia, were analyzed by gas...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02522404

    authors: Jeong BY,Ohshima T,Koizumi C

    更新日期:1996-01-01 00:00:00

  • Effects of dietary corn oil and salmon oil on lipids and prostaglandin E2 in rat gastric mucosa.

    abstract::Three groups of male rats were fed either a corn oil-enriched diet (17%, w/w), a salmon oil-enriched diet (12.5%) supplemented with corn oil (4.5%) or a low-fat diet (4.4%) for eight wk to investigate the possible relationships between dietary fatty acids and lipid composition, and prostaglandin E2 level and phospholi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535665

    authors: Grataroli R,Léonardi J,Charbonnier M,Lafont R,Lafont H,Nalbone G

    更新日期:1988-07-01 00:00:00

  • Identification of diacylglycerol acyltransferase inhibitors from Rosa centifolia petals.

    abstract::Diacylglycerol acyltransferase (DGAT) catalyzes the final step of triacylglycerol (TAG) synthesis, and is considered as a potential target to control hypertriglyceridemia or other metabolic disorders. In this study, we found that the extract of rose petals suppressed TAG synthesis in cultured cells, and that the extra...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-011-3559-8

    authors: Kondo H,Hashizume K,Shibuya Y,Hase T,Murase T

    更新日期:2011-08-01 00:00:00

  • Quantitative determination of alk-1-enyl- and alkyl-glyceryl ethers in neutral lipids and phospholipids.

    abstract::A quantitative method for the simultaneous determination of alk-l-enyl- and alkyl-glyceryl ethers is described. Complete hydrogenolysis of carboxylate and phosphate esters of neutral lipids and phospholipids was achieved with lithium aluminum hydride. The hydrogenolysis products of the glyceryl ether containing lipids...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02531729

    authors: Wood R,Snyder F

    更新日期:1968-03-01 00:00:00

  • High dietary cholesterol masks type 2 diabetes-induced osteopenia and changes in bone microstructure in rats.

    abstract::Type 2 diabetes mellitus (T2DM) often occurs concurrently with high blood cholesterol or dyslipidemia. Although T2DM has been hypothesized to impair bone microstructure, several investigations showed that, when compared to age-matched healthy individuals, T2DM patients had normal or relatively high bone mineral densit...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-014-3950-3

    authors: Lapmanee S,Charoenphandhu N,Aeimlapa R,Suntornsaratoon P,Wongdee K,Tiyasatkulkovit W,Kengkoom K,Chaimongkolnukul K,Seriwatanachai D,Krishnamra N

    更新日期:2014-10-01 00:00:00

  • Oxysterol mediated changes in fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells.

    abstract::We studied the actions of oxysterols on fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells. Cultures were labeled with [1-14C]arachidonate or [1-14C]oleate. During a 24-hr incubation, 25- or 22R-hydroxycholesterol enhanced the incorporation of label into triglycerides, concomitan...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544334

    authors: Seillan C

    更新日期:1990-03-01 00:00:00

  • Low-density lipoproteins are more electronegatively charged in type 1 than in type 2 diabetes mellitus.

    abstract::Multifactorial etiology is involved in premature atherosclerosis related to diabetes. Most of the mechanisms that are responsible for the etiology in diabetes have remained unsolved so far. Type 1 diabetes is associated with a favorable lipid pattern and with microangiopathy, which is not true for type 2 diabetes, whi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-006-5001-1

    authors: Gambino R,Pisu E,Pagano G,Cassader M

    更新日期:2006-06-01 00:00:00

  • Enrichment of LDL with EPA and DHA decreased oxidized LDL-induced apoptosis in U937 cells.

    abstract::Oxidized LDL (oxLDL) may contribute to the accumulation of apoptotic cells in atherosclerotic plaques. Although it is well established in monophasic chemical systems that the highly unsaturated EPA and DHA will oxidize more readily than FA that contain fewer double bonds, our previous studies showed that enrichment of...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-002-0962-7

    authors: Wu T,Geigerman C,Lee YS,Wander RC

    更新日期:2002-08-01 00:00:00

  • Evaluation of lipophilic antioxidant efficacy in vivo by the biomarkers hydroxyoctadecadienoic acid and isoprostane.

    abstract::The evaluation of antioxidant activity in vivo is difficult. In this study, the effects of dietary natural and synthetic antioxidants on the lipid peroxidation in mice were assessed using a biomarker, total hydroxyoctadecadienoic acid (tHODE). Biological samples such as plasma, erythrocytes, and tissues were first red...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-007-3043-7

    authors: Yoshida Y,Hayakawa M,Habuchi Y,Itoh N,Niki E

    更新日期:2007-05-01 00:00:00

  • Trans10,cis15 18:2 Isolated from Beef Fat Does Not Have the Same Anti-Adipogenic Properties as Trans10,cis12-18:2 in 3T3-L1 Adipocytes.

    abstract::During ruminal biohydrogenation of α-linolenic acid, a non-conjugated non-methylene interrupted dienoic acid is formed containing a t10 double bond, namely t10,c15-18:2. The present study was designed to examine whether t10,c15-18:2 would exert similar anti-adipogenic effects compared to t10,c12-18:2 in 3T3-L1 adipocy...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-016-4192-3

    authors: Vahmani P,Meadus WJ,Rolland DC,Duff P,Dugan ME

    更新日期:2016-11-01 00:00:00

  • 24-Methylenelanost-9(11)-en-3beta-ol, new triterpene alcohol from shea butter.

    abstract::A new triterpene alcohol was isolated fron shea butter and its structure was shown to be 24-methylenelanost-9(11)-en-3beta-ol. Gas chromatographic correlations between this triterpene alcohol and other related compounds are discussed. ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532428

    authors: Itoh T,Tamura T,Matsumoto T

    更新日期:1975-08-01 00:00:00

  • Effects of different fractions of the barley kernel on the hepatic lipid metabolism of chickens.

    abstract::Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534592

    authors: Burger WC,Qureshi AA,Prentice N,Elson CE

    更新日期:1982-12-01 00:00:00

  • Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: regulation by a high-affinity Zn2+ binding site.

    abstract::Saccharomyces cerevisiae cells were demonstrated to contain lysophosphatidylcholine (lysoPtdCho) acyltransferase (E.C. 2.3.1.23) activity. The enzyme displayed Km(app) of 69 microM for lysoPtdCho and 152 microM for oleoyl CoA. Enzyme activity was not affected by the addition of 1 mM Mg2+, Mn2+, Ca2+, or 200 mM EDTA. H...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-998-0328-1

    authors: Richard MG,McMaster CR

    更新日期:1998-12-01 00:00:00

  • Lipid and fatty acid composition is altered in plaque tissue from multiple sclerosis brain compared with normal brain white matter.

    abstract::Plaques and white matter from brains of multiple sclerosis (MS) patients were analyzed for lipid content, class composition, and fatty acid composition of total lipid, together with the fatty acid composition of plaque glycerophospholipids, and the results were compared with white matter from normal brain. Plaques con...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544017

    authors: Wilson R,Tocher DR

    更新日期:1991-01-01 00:00:00

  • Comparative studies on composition of cardiac phospholipids in rats fed different vegetable oils.

    abstract::Male Sprague-Dawley rats were fed diets for 1 or 16 weeks, containing 20% by weight vegetable oils differing widely in their oleic, linoleic and linolenic acid content. No significant changes were observed in the level of the cardiac lipid classes. The fatty acid composition of the 2 major phospholipids, phosphatidylc...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534015

    authors: Kramer JK

    更新日期:1980-09-01 00:00:00

  • Comparison of the effects of dietary alpha-linolenic, stearidonic, and eicosapentaenoic acids on production of inflammatory mediators in mice.

    abstract::The effects of dietary stearidonic acid (18:4n-3) on inflammatory mediator release in whole blood and splenocytes was investigated in Balb/c mice, and the effects were compared with those of two other n-3 PUFA: alpha-linolenic acid (18:3n-3) and EPA (20:5n-3). TAG mixtures containing 10% of 18:4n-3, 18:3n-3, or 20:5n-...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-002-0921-3

    authors: Ishihara K,Komatsu W,Saito H,Shinohara K

    更新日期:2002-05-01 00:00:00

  • Preparation ofcis,cis,cis-5,8,11-eicosatrienoic acid from arachidonic acid.

    abstract::Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methylcis,cis,cis-5,8,11-eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534947

    authors: Ghosh A,Koley M,Dutta J

    更新日期:1982-04-01 00:00:00