Cholesterol synthesis and esterification in isolated enterocytes: regulation by cholesterol and cholestyramine feeding.

abstract：:The effects of increasing concentrations of eicosapentaenoic acid (20:5n-3; EPA) and oleic acid (18:1n-9; OA) on esterification to triacylglycerols (TG) and phospholipids (PL), and the relationship to formation and secretion of the very low density lipoproteins (VLDL) were compared in the isolated perfused rat liver. ...

journal_title：Lipids

authors： Zhang ZJ,Wilcox HG,Castellani L,Fungwe TV,Elam MB,Heimberg M

更新日期：1993-05-01 00:00:00

abstract：:The particular interest in supplementing human foods with n-3 fatty acids has arisen from the findings that this series of polyunsaturated fatty acids (PUFA) have an impact on neuronal functions. Indeed vertebrates, including humans, preferentially use docosahexaenoic acid (DHA, 22:6n-3) over other long-chain n-3 PUFA...

journal_title：Lipids

authors： Pifferi F,Perret M,Guesnet P,Aujard F,Alessandri JM

更新日期：2012-08-01 00:00:00

abstract：:Skeletal muscle plays a major role in insulin-stimulated glucose disposal. This paper reviews the range of evidence in humans and experimental animals demonstrating close associations between insulin action and two major aspects of muscle morphology: fatty acid composition of the major structural lipid (phospholipid) ...

journal_title：Lipids

authors： Storlien LH,Pan DA,Kriketos AD,O'Connor J,Caterson ID,Cooney GJ,Jenkins AB,Baur LA

更新日期：1996-03-01 00:00:00

abstract：:The composition of the glycosphingolipids of the human gastrointestinal tract was studied. The major neutral glycosphingolipids were ceramide monohexosides (e.g., GalCer, GlcCer), LacCer, Gb3Cer, Gb4Cer and more polar ones with more than four sugars, whereas neither Gg3Cer nor Gg4Cer were present. The acidic glycosphi...

journal_title：Lipids

authors： Natomi H,Saitoh T,Sugano K,Iwamori M,Fukayama M,Nagai Y

更新日期：1993-08-01 00:00:00

abstract：:Lysophosphatidic acid (lysoPtdOH), a lysophospholipid mediator, exerts diverse physiological effects, including angiogenesis, through its specific G-protein-coupled receptors. Previously, we showed that unfertilized hen egg white contains polyunsaturated fatty acid-rich lysoPtdOH and lysophospholipase D (lysoPLD). Her...

journal_title：Lipids

authors： Morishige J,Uto Y,Hori H,Satouchi K,Yoshiomoto T,Tokumura A

更新日期：2013-03-01 00:00:00

abstract：:This study proposed lipid fingerprinting of human seminal plasma by mass spectrometry as an analytical method to differentiate biological conditions. For this purpose, we chose infertile men as a model to study specific conditions, namely: high and low seminal plasma lipid peroxidation levels (sub-study 1.1), high and...

journal_title：Lipids

authors： Camargo M,Intasqui P,de Lima CB,Montani DA,Nichi M,Pilau EJ,Gozzo FC,Lo Turco EG,Bertolla RP

更新日期：2014-09-01 00:00:00

abstract：:The reaction products of alpha-tocopherol and its model compound, 2,2,5,7,8-pentamethylchroman-6-ol, during the autoxidation of methyl linoleate at 37 C were investigated. Two isomeric trimers were obtained as the major reaction products of alpha-tocopherol, and a trimer was obtained as that of its model chroman. The ...

journal_title：Lipids

authors： Yamauchi R,Kato K,Ueno Y

更新日期：1988-08-01 00:00:00

abstract：:The relationship between LCAT mediated HDL modification and the redistribution of lipoprotein-unassociated apoA-IV to HDL was investigated in vitro. Immunoaffinity-isolated rat lipoprotein-unassociated apoA-IV was added to apoB-, apoE-, apoA-IV depleted, [3H]cholesterol labelled rat plasma and incubated at 37 degrees ...

journal_title：Lipids

authors： Lefevre M,Goudey-Lefevre JC,Roheim PS

更新日期：1989-12-01 00:00:00

abstract：:FA ethyl esters (FAEE) are nonoxidative metabolites of ethanol produced by the esterification of FA and ethanol. FAEE have been implicated as mediators of ethanol-induced organ damage in vivo and in vitro, and are markers of ethanol intake. Upon ethanol intake, FAEE are synthesized in the liver and pancreas in signifi...

journal_title：Lipids

authors： Hasaba A,Cluette-Brown JE,Laposata M

更新日期：2003-10-01 00:00:00

abstract：:Oxidized LDL (oxLDL) has been shown to activate the sphingomyelinase pathway producing ceramide in vascular smooth muscle cells. Therefore ceramide, which is a biologically active lipid causing apoptosis in a variety of cells, may be involved in the apoptotic action of oxLDL. In this study, we examined whether cholest...

journal_title：Lipids

authors： Ichi I,Takashima Y,Adachi N,Nakahara K,Kamikawa C,Harada-Shiba M,Kojo S

更新日期：2007-10-01 00:00:00

abstract：:Facile procedures are described for nearly quantitative conversion of saturated and unsaturated fatty aldehydes to their dimethyl acetals, and vice versa, at low temperatures. The methods are based on the chemical behavior of aldehydes and dimethyl acetals in 100% sulfuric acid. Under the experimental conditions descr...

journal_title：Lipids

authors： Mahadevan V,Viswanathan CV,Lundberg WO

更新日期：1966-09-01 00:00:00

abstract：:The aim of the present study was to identify the effects of dehydroepiandrosterone (DHEA) on hepatic lipid metabolism parameters and lipogenic gene mRNA expression in broiler chickens. A total of 72 1-day-old broiler chicks received a common basal diet with DHEA added at either 0 (control), 5 or 20 mg/kg feed. In the ...

journal_title：Lipids

authors： Tang X,Ma H,Zou S,Chen W

更新日期：2007-11-01 00:00:00

abstract：:To examine whether dietary fat alters membrane lipid composition and peroxidation of polyunsaturated fatty acids in "non-proliferative" and "proliferative" cells in the large intestine, Sprague-Dawley rats were fed diets providing a polyunsaturated-to-saturated fatty acid ratio of 1.2 or 0.3 at a high or low level of ...

journal_title：Lipids

authors： Turini ME,Thomson AB,Clandinin MT

更新日期：1991-06-01 00:00:00

abstract：:In order to determine the minimal amount of dietary 9-trans, 12-trans-linoleate which can decrease endoperoxide metabolites synthesized and their precursor in rat platelets, graded amounts (0, 0.1, 0.5, 1.0, 2.5%) of the trans-linoleate were fed to rats with a constant amount of all-cis-linoleate (2.5%) for 12 weeks. ...

journal_title：Lipids

authors： Hwang DH,Chanmugam P,Anding R

更新日期：1982-04-01 00:00:00

abstract：:Six oils of marine, algal, and microbial origin were analyzed for stereospecific distribution of component fatty acids. The general procedure involved preparation of sn-1,2-(2,3)-diacylglycerols by partial deacylation with ethylmagnesium bromide or pancreatic lipase, separation of X-1,3- and sn-1,2(2,3)-diacylglycerol...

journal_title：Lipids

authors： Myher JJ,Kuksis A,Geher K,Park PW,Diersen-Schade DA

更新日期：1996-02-01 00:00:00

abstract：:Eighteen-month-old Nebraska strain minipigs were fed diets containing 2% cholesterol and 20% corn oil, lard, or coconut oil for 12 to 18 months. Concentrations of serum total lipid, total cholesterol, and total phospholipid increased 200 to 300% with each diet. Changes in serum concentrations of Sf 20+ and Sf 0-20 lip...

journal_title：Lipids

authors： Goldsmith DP,Jacob HP

更新日期：1978-03-01 00:00:00

abstract：:Enrichment of beef muscle with n-3 fatty acids (FA) is one means to introduce these FA into the diet, but ruminal biohydrogenation limits their bioavailability. To address this problem, we evaluated the ability of condensed tannin (quebracho), in the presence or absence of casein, to protect 18:3n-3 in flaxseed from h...

journal_title：Lipids

authors： Kronberg SL,Scholljegerdes EJ,Barceló-Coblijn G,Murphy EJ

更新日期：2007-12-01 00:00:00

abstract：:An analysis of the phospholipid, cholesterol, and phospholipid fatty acyl composition of isolated plasma membranes of 3T3 and SV3T3 mouse mebryo cells has been performed. The results show that the plasma membrane of SV3T3 cells contain relatively less phosphatidylethanolamine and sphingomyelin and more cholesterol tha...

journal_title：Lipids

authors： Perkins RG,Scott RE

更新日期：1978-10-01 00:00:00

abstract：:Two novel lipopeptides, which have the peptide ligands [alpha-melanocyte stimulating hormone (alpha-MSH)] sequence and repeated [Gly-Arg-Gly-Asp-Se (GRGDS) sequence], are designed, synthesized by the solid-phase method, and introduced into liposome membranes by the freeze-thaw method. These liposomes bearing the pepti...

journal_title：Lipids

authors： Yagi N,Ogawa Y,Kodaka M,Okada T,Tomohiro T,Konakahara T,Okuno H

更新日期：2000-06-01 00:00:00

abstract：:In vivo intestinal perfusion was used to follow the absorption of three different choline glycerophospholipids (CGP) in guinea pig. These included 1-[3H]palmitoyl-2-acyl-sn-glycero-3-phosphocholine (diacyl-GPC), 1-[3H]-O-hexadecyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) and 1,2-di-O-hexadecyl-sn-glycero-3-p...

journal_title：Lipids

authors： Diagne A,Mitjavila S,Fauvel J,Chap H,Douste-Blazy L

更新日期：1987-01-01 00:00:00

abstract：:The purpose of this study was to examine the effect of dietary docosahexaenoic acid (DHA), in the absence of eicosapentaenoic acid, on human immune response (IR). A 120-d study with 11 healthy men was conducted at the Metabolic Research Unit of the Western Human Nutrition Research Center. Four subjects (control group)...

journal_title：Lipids

authors： Kelley DS,Taylor PC,Nelson GJ,Mackey BE

更新日期：1998-06-01 00:00:00

abstract：:Male weanling rats were fed semi-synthetic diets high in saturated fat (beef tallow) vs high in linoleic acid (safflower oil) with or without high levels of alpha-linolenic acid (linseed oil) for a period of 28 days. The effect of feeding these diets on cholesterol content and fatty acid composition of serum and liver...

journal_title：Lipids

authors： Garg ML,Wierzbicki AA,Thomson AB,Clandinin MT

更新日期：1989-04-01 00:00:00

abstract：:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

journal_title：Lipids

authors： Masuno H,Okuda H

更新日期：1985-07-01 00:00:00

abstract：:The effect of various physicochemical forms of substrate on the activity of acid cholesteryl ester hydrolase isolated from rat liver lysosomes was studied. The amount of sodium taurocholate was varied in the substrate mixture which contained constant amounts of egg phosphatidylcholine (PC) and cholesteryl oleate. The ...

journal_title：Lipids

authors： Klemets R,Lundberg B

更新日期：1986-08-01 00:00:00

abstract：:This study was designed to determine the nutritional lipid requirement of Manchurian trout and to investigate the effects of lipid concentrations on the antioxidant status in larvae with experimental diets with different lipid levels. Oxidative stress differences between different organs and tissues were also assessed...

journal_title：Lipids

authors： Zhang H,Mu Z,Xu L,Xu G,Liu M,Shan A

更新日期：2009-07-01 00:00:00

abstract：:The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

journal_title：Lipids

authors： Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

更新日期：1981-10-01 00:00:00

abstract：:The separation of lecithin derivatives based on their fatty acid substituents has been investigated. Several synthetic and natural lecithins were converted to their corresponding dimethylphosphatidates by hydrolysis with phospholipase D (phosphatidylcholine phospholipase D (phosphatidylcholine phosphatidohydrolase, EC...

journal_title：Lipids

authors： Wurster CF Jr,Copenhaver JH Jr

更新日期：1966-11-01 00:00:00

abstract：:Essential fatty acids are structural components of all tissues and are indispensable for cell membrane synthesis; the brain, retina and other neural tissues are particularly rich in long-chain polyunsaturated fatty acids (LC-PUFA). These fatty acids serve as specific precursors for eicosanoids, which regulate numerous...

journal_title：Lipids

authors： Uauy R,Hoffman DR,Peirano P,Birch DG,Birch EE

更新日期：2001-09-01 00:00:00

abstract：:The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

journal_title：Lipids

authors： Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

更新日期：2019-09-01 00:00:00

abstract：:Steroids bearing ketone functionality at carbon-7 are found commonly in nature, and the most prevalent of these are the 7-keto-delta5-sterols. These substances have diverse biological properties and are present in biological samples and food products. For the purpose of studying this class of oxysterols, many chemical...

journal_title：Lipids

authors： Parish EJ,Kizito SA,Qiu Z

更新日期：2004-08-01 00:00:00