Abstract：
:Enrichment of beef muscle with n-3 fatty acids (FA) is one means to introduce these FA into the diet, but ruminal biohydrogenation limits their bioavailability. To address this problem, we evaluated the ability of condensed tannin (quebracho), in the presence or absence of casein, to protect 18:3n-3 in flaxseed from hydrogenation by ruminal microbes in cattle using an in vitro fermentation approach coupled with evaluation in cattle in vivo. Treated and untreated flaxseed was incubated with bovine rumen fluid for 0 and 24 h. With tannin treated flaxseed, hydrogenation of 18:3n-3 was limited to only 13% over 24 h compared to 43% for untreated flaxseed, while addition of casein to the tannin added no additional protection. To determine if a similar level of protection would occur in vivo, we used two groups of five steers fed either a grain-based or forage-based diet. Five steers were given a grain-based diet during the trial and were fed either ground flaxseed or tannin treated flaxseed for 15 days prior to blood collection for plasma lipid fatty acid analysis. The forage fed steers followed the same regimen. Ingestion of tannin-treated flaxseed did not increase 18:3n-3 and 20:5n-3 in plasma neutral lipids as compared to non-treated flaxseed. Thus, we demonstrated that treating ground flaxseed with quebracho tannin is not useful for increasing 18:3n-3 in the neutral lipid of bovine blood plasma, and suggest caution when interpreting results from in vitro trials that test potential treatments for protecting fatty acids from hydrogenation by ruminal microbes.
journal_name
Lipidsjournal_title
Lipidsauthors
Kronberg SL,Scholljegerdes EJ,Barceló-Coblijn G,Murphy EJdoi
10.1007/s11745-007-3126-5subject
Has Abstractpub_date
2007-12-01 00:00:00pages
1105-11issue
12eissn
0024-4201issn
1558-9307journal_volume
42pub_type
杂志文章相关文献
LIPIDS文献大全abstract：:The effect of 1.7-2.2 mg/day oral phenobarbital over short (1 MO) and long term (6-24 MO) treatment on primary bile acid (BA) secretion, composition, synthesis, pool size, and enterohepatic cycling rates as well as phospholipid (PL) and cholesterol (C) secretion rates and biliary composition was determined in 12 asymp...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02533915
更新日期：1979-03-01 00:00:00
abstract：:We describe a method for the quantitative analysis of molecular species of diacylglycerol and alkylacylglycerol as their diradylglycerobenzoate derivatives. Synthetic internal standards were used to provide quantitative determinations of the low levels of diacylglycerol and alkylacylglycerol and their individual molec...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02544045
更新日期：1990-11-01 00:00:00
abstract：:The biosynthesis of 3R-hydroxy-5Z, 8Z, 11Z,14Z-eicosatetraenoic acid (3R-HETE) from arachidonic acid (20:4n-6) by the hyphal-forming yeast, Dipodascopsis uninucleata, in cell-free enzyme extracts required CoASH, ATP, NAD+ and Mg2+; 3R-HETE was present as the CoA derivative in enzyme extracts and its biosynthesis was a...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-000-0637-4
更新日期：2000-11-01 00:00:00
abstract：:Cholesterol biosynthesis from acetate-2-(14)C by the livers of suckling rats, which is known to be relatively slow, was increased 2-3-fold within 24 hours after severing the bile duct. Cholesterol synthesis by sham-operated litter mates showed no change under similar treatment. Mevalonate biosynthesis from acetate-2-(...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02530913
更新日期：1967-03-01 00:00:00
abstract：:The growing prevalence of childhood obesity has become a serious health problem over the past few decades. Although the immune system is greatly affected by childhood obesity, whether obesity influences the T cell development in the thymus is poorly understood. In this study, we used a high-fat diet (HFD)-induced obes...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1002/lipd.12193
更新日期：2020-01-01 00:00:00
abstract：:Fatty acid synthetase purified (20 times) from lactating bovine mammary tissue had an approximate mot wt of 485,000. The enzyme had a high content of acidic and hydrophobic amino acid residues; 62±4 sulhydryl groups and one 4' phosphopantetheine residue/mole of enzyme. The enzyme was relatively stable when stored (3 m...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02532485
更新日期：1975-04-01 00:00:00
abstract：:Using primary rat hepatocyte cultures, the potency of several garlic-derived organosulfur compounds to inhibit cholesterol biosynthesis in toto as well as at early and late steps of this metabolic pathway was compared. Concerning early steps, allicin significantly inhibited incorporation of [14C]acetate into nonsaponi...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02587912
更新日期：1996-12-01 00:00:00
abstract：:Excessive or inappropriate inflammation and immunosuppression are components of the response to surgery, trauma, injury, and infection in some individuals and these can lead, progressively, to sepsis and septic shock. The hyperinflammation is characterized by the production of inflammatory cytokines, arachidonic acid-...
journal_title：Lipids
pub_type： 杂志文章,评审
doi：10.1007/s11745-004-1342-z
更新日期：2004-12-01 00:00:00
abstract：:The separation of lecithin derivatives based on their fatty acid substituents has been investigated. Several synthetic and natural lecithins were converted to their corresponding dimethylphosphatidates by hydrolysis with phospholipase D (phosphatidylcholine phospholipase D (phosphatidylcholine phosphatidohydrolase, EC...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02532546
更新日期：1966-11-01 00:00:00
abstract：:Azaserine induced two phenotypically different populations of foci, namely, acidophilic and basophilic foci. The effects of dietary modification during the post-initiation phase of carcinogenesis were examined. A diet of 20% (w/w) unsaturated fat (unsat) compared to a 20% saturated fat (sat) diet or a control diet (5%...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02536413
更新日期：1986-04-01 00:00:00
abstract：:Type 2 diabetes and dyslipidemia are risk factors for cardiovascular disease. However, mechanisms by which hypertriglyceridemia influences atherogenesis remain unclear. We examined effects of dyslipidemic diabetic serum on macrophage lipid accumulation as a model of foam cell formation. Normal human macrophages were c...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-011-3578-5
更新日期：2011-10-01 00:00:00
abstract：:Taurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7 alpha-hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7 alpha-hydroxylated to form taurocholic acid. The low concentrations of secondary bile acids observe...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02534573
更新日期：1983-12-01 00:00:00
abstract：:Rats were fed diets with three different ratios of alpha-linolenate (18:3 n-3) and linoleate (18:2 n-6), and then crescentic-type anti-glomerular basement membrane (GBM) nephritis was induced. The urinary protein levels and the plasma urea nitrogen levels were significantly higher, and histological abnormalities of gl...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02544386
更新日期：1990-05-01 00:00:00
abstract：:This study was undertaken to determine the effect of various lipid emulsions on the hepato-biliary system in rats. Rats were randomly divided into six groups and infused continuously for 48 hr with either long-chain triglycerides (LCT), medium-chain triglycerides (MCT) or a mixture of MCT and LCT. One group infused wi...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02536144
更新日期：1992-05-01 00:00:00
abstract：:The biosynthesis of [14C] CDP-diglyceride was studied using rat liver microsomes which were endogenously labeled with [14C] phosphatidic acid by preincubation of unlabeled microsomes with sn-[14C] glycerol-3-phosphate and appropriate cofactors. The formation of CDP-diglyceride from radioactive phosphatidate showed an ...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02544050
更新日期：1976-04-01 00:00:00
abstract：:Plaques and white matter from brains of multiple sclerosis (MS) patients were analyzed for lipid content, class composition, and fatty acid composition of total lipid, together with the fatty acid composition of plaque glycerophospholipids, and the results were compared with white matter from normal brain. Plaques con...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02544017
更新日期：1991-01-01 00:00:00
abstract：:Treatment of (13S,9Z,11E)-13-hydroperoxy-9,11-octadecadienoic acid (13S-HPODE) with strong alkali resulted in the formation of about 75% of the corresponding hydroxy acid, (13S,9Z,11E)-13-hydroxy-9,11-octadecadienoic acid (13S-HODE), and the remaining 25% of products was a mixture of several oxidized fatty acids, the ...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02522458
更新日期：1996-10-01 00:00:00
abstract：:Oxidative stress is thought to play an important role in atherogenesis. The statin group of cholesterol-lowering drugs have been shown to reduce cardiovascular events and possess antioxidant properties. We aimed to assess the effects of simvastatin on a novel measure of prooxidant-antioxidant balance (PAB) in dyslipid...
journal_title：Lipids
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11745-010-3517-x
更新日期：2011-04-01 00:00:00
abstract：:A method is described for the determination of the positions and geometric configurations of double bonds in polyunsaturated fatty acids. The procedure consists of three steps: 1) Partial reduction of the double bonds with hydrazine under conditions which give high yields of monoenes. 2) Isolation of thecis- and thetr...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02532998
更新日期：1966-03-01 00:00:00
abstract：:Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-013-3770-x
更新日期：2013-04-01 00:00:00
abstract：:The total lipids, total neutral lipids, and total phospholipids from Aedes aegypti and aedes albopictus cells cultivated in vitro in a medium containing fetal calf serum were analyzed. The mosquito cells were harvested in the logarithmic and stationary phases of growth. The fatty acid profiles of the lipids showed dif...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02532163
更新日期：1975-02-01 00:00:00
abstract：:Apolipoprotein (apoB) plays a fundamental role in the transport and metabolism of plasma triacylglycerols (TAGs) and cholesterol. Several apoB polymorphic sites have been studied for their potential use as markers for coronary heart disease in the population. In view of the importance of apoB in postprandial metabolis...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-007-3027-7
更新日期：2007-03-01 00:00:00
abstract：:Epoxidation of the double bond in methyl oleate, octadec-11E-en-9-ynoate, ricinoleate (12-hydroxy-octadec-9Z-enoate), iso-ricinoleate (9-hydroxy-octadec-12Z-enoate), and 12-oxo-octadec-9Z-enoate with potassium peroxomonosulfate (oxone, 2 KHSO5.KHSO4.K2SO4) in the presence of trifluoroacetone or methyl pyruvate gave th...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-998-0250-6
更新日期：1998-06-01 00:00:00
abstract：:Ceramide 2-aminoethylphosphonate (CAEP), a sphingophosphonolipid containing a carbon-phosphorus bond, is frequently found in marine organisms and has a unique triene type of sphingoid base in its structure. CAEP has not been evaluated as a food ingredient, although it is generally contained in Mollusca organisms such ...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-017-4239-0
更新日期：2017-04-01 00:00:00
abstract：:Some studies focused on the effect of the dietary glycemic index on lipoproteins and apolipoproteins in adults; however, little evidence exists among adolescents regarding the effect of a low glycemic index (LGI) diet on apolipoproteins and lipoprotein (a) (Lpa). This study was conducted to evaluate the effect of an L...
journal_title：Lipids
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11745-013-3834-y
更新日期：2013-12-01 00:00:00
abstract：:In humans and animals, intestinal flora is indispensable for bile acid transformation. The goal of our study was to establish gnotobiotic mice with intestinal bacteria of human origin in order to examine the role of intestinal bacteria in the transformation of bile acids in vivo using the technique of gnotobiology. Ei...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-006-5038-1
更新日期：2006-09-01 00:00:00
abstract：:The effect of phosphatidylserine and sterol carrier proteins on cholesterol exchange was determined using an assay not requiring separation of donor and acceptor membrane vesicles. Sterol carrier protein-2 (SCP2, also called nonspecific lipid transfer protein), but not fatty acid binding protein (FABP, also called ste...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02544032
更新日期：1990-11-01 00:00:00
abstract：:Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) are essential components of the diet of all vertebrates. The major dietary source of n-3 LC-PUFA for humans has been fish and seafood but, paradoxically, farmed fish are also reliant on marine fisheries for fish meal and fish oil (FO), traditionally major ...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/s11745-016-4191-4
更新日期：2016-10-01 00:00:00
abstract：:The metabolic fate of high density lipoprotein (HDL) sphingomyelin in plasma was studied in rats over a 24-hr period after injection of HDL containing sphingomyelin which was 14C-labeled in the stearic (18:0) or lignoceric acid (24:0) moiety and 3H-labeled in the choline methyl groups. Decay of label in plasma followe...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02536017
更新日期：1990-10-01 00:00:00
abstract：:A group of homologous, nonmethylene-interrupted dienoic fatty acids (NMID) recently reported in oysters has been found in several other shellfish species and also in other marine phyla. The distribution of most other "normal" fatty acids among several species of shellfish is basically similar but mantle lipids from tw...
journal_title：Lipids
pub_type： 杂志文章
doi：10.1007/BF02533289
更新日期：1977-02-01 00:00:00
