Essentiality of fatty acids.

abstract：:Chlorpromazine (CPZ), a major tranquilizer, was found to be a potent inhibitor of lecithin:cholesterol acyltransferase (LCAT, EC 2.3.1.43) in the plasma of normal man, rat, rabbit and dog in vitro. The inhibitory effect of CPZ reached 35-50% at 0.5 mM depending on species; dog plasma LCAT appeared to be somewhat more ...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1981-11-01 00:00:00

abstract：:This study compared (i) the relative effects of long-chain triglycerides (LCT) and medium-chain triglycerides (MCT), (ii) the influence of amount of MCT, and (iii) the impact of medium-chain fatty acid position, on plasma and lymphatic triglycerides and portal vein free fatty acids. The animals were fed approximately ...

journal_title：Lipids

authors： You YQ,Ling PR,Qu Z,Bistrian BR

更新日期：1998-03-01 00:00:00

abstract：:Despite the potential use of long chain polyunsaturated fatty acid (LCPUFA) supplementation to promote growth and neural development of the infant, little is known about potential harmful effects of the supplementation. The present study determined whether supplementation with arachidonic acid (AA) and/or docosahexaen...

journal_title：Lipids

authors： Yeh YY,Whitelock KA,Yeh SM,Lien EL

更新日期：1999-05-01 00:00:00

abstract：:Epoxidation of the double bond in methyl oleate, octadec-11E-en-9-ynoate, ricinoleate (12-hydroxy-octadec-9Z-enoate), iso-ricinoleate (9-hydroxy-octadec-12Z-enoate), and 12-oxo-octadec-9Z-enoate with potassium peroxomonosulfate (oxone, 2 KHSO5.KHSO4.K2SO4) in the presence of trifluoroacetone or methyl pyruvate gave th...

journal_title：Lipids

authors： Lie Ken Jie MS,Pasha MK

更新日期：1998-06-01 00:00:00

abstract：:Several experimental approaches were used to determine whether rat liver and testes express an acyl-CoA-dependent delta8 desaturase. When [1-14C]5,11,14-eicosatrienoic acid was injected via the tail vein, or directly into testes, it was incorporated into liver and testes phospholipids, but it was not metabolized to ot...

journal_title：Lipids

authors： Chen Q,Yin FQ,Sprecher H

更新日期：2000-08-01 00:00:00

abstract：:Microsomal and myelin membrane fractions were prepared from the brains of warm-adapted (room temperature) and hibernating Syrian Hamsters (Mesocricetus auratus). Ethanolamineglycerophospholipids were isolated and subjected to a fractionation scheme to separate the fatty acids of the plasmenylethanolamine and the phosp...

journal_title：Lipids

authors： Blaker WD,Moscatelli EA

更新日期：1979-12-01 00:00:00

abstract：:Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the k...

journal_title：Lipids

authors： Muñoz PA,Correa-Llantén DN,Blamey JM

更新日期：2015-01-01 00:00:00

abstract：:Twenty-three of 86 strains of lactic acid bacteria transformed linoleic acid into hydroxy FA. Two distinct conversion pathways were in operation. Two strains of Lactobacillus acidophilus and a strain of Pediococcus pentosaceus produced 13(S)-hydroxy-9-octadecenoic acid 113(S)-OH 18:11 and 10,13dihydroxyoctadecanoic ac...

journal_title：Lipids

authors： Kishimoto N,Yamamoto I,Toraishi K,Yoshioka S,Saito K,Masuda H,Fujita T

更新日期：2003-12-01 00:00:00

abstract：:We have studied the effect of various diets on the phospholipid fatty acid composition and in vitro delta 5 desaturase activity of hepatic microsomes derived either from the normal or streptozotocin-induced diabetic rat. The diets studied were the standard rat chow diet and a basal fat-free diet supplemented either wi...

journal_title：Lipids

authors： Dang AQ,Kemp K,Faas FH,Carter WJ

更新日期：1989-10-01 00:00:00

abstract：:The cholesterol-suppressive action of the tocotrienol-rich-fraction (TRF) of palm oil may be due to the effect of its constituent tocotrienols on beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase activity. The tocotrienols, modulate HMG-CoA reductase activity via a post-transcriptional mechanism. As a co...

journal_title：Lipids

authors： Yu SG,Thomas AM,Gapor A,Tan B,Qureshi N,Qureshi AA

更新日期：2006-05-01 00:00:00

abstract：:The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphe...

journal_title：Lipids

authors： Khan AA,Husain A,Jabeen M,Mustafa J,Owais M

更新日期：2012-10-01 00:00:00

abstract：:The oils from sclerotia or from suitable mycelial cultures ofClaviceps purpurea (ergot) contain up to 44% of ricinoleic acid but no free hydroxyl groups. This is due to the presence of, besides normal triglycerides, tetra-acid, penta-acid and hexa-acid triglycerides. These contain respectively one, two and three ricin...

journal_title：Lipids

authors： Morris LJ,Hall SW

更新日期：1966-05-01 00:00:00

abstract：:A method for the simultaneous quantitative analysis of prostaglandin E2 (PGE2) and PGE3 is described. The PG were analyzed by selected ion monitoring as the methyl ester-TMS ether derivatives of PGB2 and PGB3, respectively. The internal standard for the quantification of both species was [3,3,4,4-2H4]PGE2. A linear re...

journal_title：Lipids

authors： Ferretti A,Flanagan VP,Roman JM

更新日期：1982-11-01 00:00:00

abstract：:Dietary fatty acids have different effects on fat deposition in pigs. To clarify the underlying mechanisms of this difference, we compared the metabolism of palmitic (PAM, saturated), oleic (OLA, monounsaturated) and linoleic acid (LNA, polyunsaturated) in porcine adipocytes treated with 100 μM PAM, OLA or LNA. We obs...

journal_title：Lipids

authors： Yu C,Xi L,Chen J,Jiang Q,Yi H,Wang Y,Wang X

更新日期：2017-11-01 00:00:00

abstract：:A sucrose-rich diet (SRD) induces insulin resistance and dyslipidemia with impaired hepatic glucose production and gluconeogenesis, accompanied by altered post-receptor insulin signaling steps. The aim of this study was to examine the effectiveness of fish oil (FO) to reverse or improve the impaired hepatic glucose me...

journal_title：Lipids

authors： Hein GJ,Chicco A,Lombardo YB

更新日期：2012-02-01 00:00:00

abstract：:Choline kinase was located in the cytosolic fractions of the filamentous, pathogenic fungi,Microsporum gypseum andEpidermophyton floccosum. A broad pH optima (6.0-9.0) was observed for theM. gypseum enzyme, but theE. floccosum enzyme was active at pH 8.4 as well as 10.5, the activity being higher at pH 8.4. Enzyme fro...

journal_title：Lipids

authors： Kasinathan C,Govindarajan U,Chopra A,Khuller GK

更新日期：1983-10-01 00:00:00

abstract：:The skin surface lipid of the dog has been reported to contain a high proportion of diol diesters having a lower mobility on thin layer chromatography than diesters from other species in spite of containing similar fatty acid and diol components. In the present study, dog skin surface lipid was separated by preparativ...

journal_title：Lipids

authors： Sharaf DM,Clark SJ,Downing DT

更新日期：1977-10-01 00:00:00

abstract：:The cleavage products formed by autoxidation of lycopene were evaluated in order to elucidate possible oxidation products of lycopene in biological tissues. Lycopene solubilized at 50 microM in toluene, aqueous Tween 40, or liposomal suspension was oxidized by incubating at 37 degrees C for 72 h. Among a number of oxi...

journal_title：Lipids

authors： Kim SJ,Nara E,Kobayashi H,Terao J,Nagao A

更新日期：2001-02-01 00:00:00

abstract：:The pulp from unerupted calves' teeth was found to contain low levels of glycerol ester hydrolase activity. Solutions in Tris buffer cleared tributyrylglycerol agar and hydrolyzed emulsified olive oil. The average quantity of free fatty acids released in five assays with olive oil was: 2.8, S.D.+/-1.4. Specific activi...

journal_title：Lipids

authors： McMahon KE,Pitas RE,Jensen RG

更新日期：1977-02-01 00:00:00

abstract：:The uptake of lipid from the yolk by the yolk sac membrane of the chick embryo is accompanied by the rapid esterification of a large proportion of the yolk cholesterol. This could arise from enhanced acyl-CoA:cholesterol acyltransferase (ACAT) activity and/or inhibition of cholesteryl ester hydrolase (CEH) activity. T...

journal_title：Lipids

authors： Shand JH,West DW,McCartney RJ,Noble RC,Speake BK

更新日期：1993-07-01 00:00:00

abstract：:Cholesteryl esterase activities were determined in homogenates of rat heart (ventricles), isolated, calcium-tolerant, cardiac myocytes and aortic tissue and were compared with acid and neutral triglyceride lipase activities in these fractions. Using cholesteryl oleate/phosphatidylcholine/taurocholate emulsions and dig...

journal_title：Lipids

authors： Stam H,Broekhoven-Schokker S,Schoonderwoerd K,Hülsmann WC

更新日期：1987-02-01 00:00:00

abstract：:To see how the metabolism of specific phosphatidyl choline fractions might be affected when only a limited source of methyl groups was available, rats were fed for 7 days a low methionine, choline-deficient diet or one supplemented with either choline or methionine. Prior to killing, they were injected with -14C-methy...

journal_title：Lipids

authors： Lyman RL,Giotas C,Medwadowski B,Miljanich P

更新日期：1975-03-01 00:00:00

abstract：:Previous studies from our laboratory have shown that retinitis pigmentosa (RP), a family of hereditary retinal degenerations, is often accompanied by abnormal levels of cholesterol or polyunsaturated fatty acids. The requirement of the retina for n-3 fatty acids is well known, and a defect in the supply of these lipid...

journal_title：Lipids

authors： Huq L,McLachlan T,Hammer HM,Bedford D,Packard CJ,Shepherd J,Converse CA

更新日期：1993-11-01 00:00:00

abstract：:Plasma phospholipid transfer protein (PLTP) mediates both net transfer and exchange of phospholipids between different lipoproteins. Animal studies have shown that it is closely related to the development of atherosclerosis. Although many studies have indicated that PLTP activity is increased in diabetes mellitus, the...

journal_title：Lipids

authors： Schlitt A,Schwaab B,Fingscheidt K,Lackner KJ,Heine GH,Vogt A,Buerke M,Maegdefessel L,Raaz U,Werdan K,Jiang XC

更新日期：2010-02-01 00:00:00

abstract：:Both diacyl GPC (glycerylphosphorylcholine) and diacyl GPE (glycerylphosphorylethanolamine) are synthesized in human placental tissue from their respective monoacyl precursors. The origin of the monacyl phosphatides is apparently not the result of placental phosphatide acyl-hydrolase activity. The most likely source i...

journal_title：Lipids

authors： Robertson A,Sprecher H

更新日期：1967-09-01 00:00:00

abstract：:The tail gland of the red fox (Vulpes vulpes) secretes lipids containing volatile terpenes used in social communication. We have analysed lipids extracted from fur of the tail gland, body (flanks) and muzzle of foxes. GC-MS showed a novel group of iso-valerate and tiglate monoesters of alkane-1,2-diols (C18:0-22:0). T...

journal_title：Lipids

authors： McLean S,Davies NW,Nichols DS

更新日期：2017-07-01 00:00:00

abstract：:Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance. ...

journal_title：Lipids

authors： Smith LL

更新日期：1996-05-01 00:00:00

abstract：:The ganglioside and neutral glycosphingolipid composition of adult monkey small and large intestinal mucosa were characterized and compared. GM3, GM2 and GD1A were found to be the principal gangliosides in each of these tissues. Dihexosylceramide was the major neutral glycosphingolipid of both organs. The total conten...

journal_title：Lipids

authors： Dahiya R,Brown MD,Brasitus TA

更新日期：1986-02-01 00:00:00

abstract：:One of the main biological systems that can be used as a model for studying the molecular mechanisms involved in membrane fusion is the formation of the nuclear envelope (NE). NE assembly to form the male pronucleus at fertilization occurs by binding of NE membrane precursor vesicles to chromatin and their fusion. MV1...

journal_title：Lipids

authors： Larijani B,Dufourc EJ

更新日期：2006-10-01 00:00:00

abstract：:We previously reported that phospholipids markedly affected the uptake of carotenoids solubilized in mixed micelles by human intestinal Caco-2 cells. In the present study, we found that two classes of dietary glyceroglycolipids and the corresponding lysoglyceroglycolipids affected uptake of β-carotene and lutein by di...

journal_title：Lipids

authors： Kotake-Nara E,Yonekura L,Nagao A

更新日期：2015-09-01 00:00:00