Lipid peroxidation during n-3 fatty acid and vitamin E supplementation in humans.

abstract：:Conjugated linoleic acid (CLA) has been demonstrated to reduce body fat in animals. However, the mechanism by which this reduction occurs is unknown. Leptin may mediate the effect of CLA to decrease body fat. We assessed the effects of 64 d of CLA supplementation (3 g/d) on circulating leptin, insulin, glucose, and la...

journal_title：Lipids

authors： Medina EA,Horn WF,Keim NL,Havel PJ,Benito P,Kelley DS,Nelson GJ,Erickson KL

更新日期：2000-07-01 00:00:00

abstract：:A maternal high fat diet (HFD) can have adverse effects on skeletal muscle development. Skeletal muscle PLIN proteins (PLIN2, 3 and 5) are thought to play critical roles in lipid metabolism, however effects of HFD on PLIN and lipases (HSL, ATGL, CGI-58) in mothers as well as their offspring have yet to be investigated...

journal_title：Lipids

authors： MacPherson RE,Castelli LM,Miotto PM,Frendo-Cumbo S,Milburn A,Roy BD,LeBlanc PJ,Ward WE,Peters SJ

更新日期：2015-02-01 00:00:00

abstract：:Triacylglycerols containing linoleate and linolenate found in vegetable oils were synthesized in gram quantities for oxidation studies. Two acylation methods were examined to convert diacylglycerols or monoacylglycerols to the desired triacylglycerols. Acylations with fatty acid and 1,1'-dicyclohexylcarbodiimide in th...

journal_title：Lipids

authors： Awl RA,Frankel EN,Weisleder D

更新日期：1989-10-01 00:00:00

abstract：:Water and lipid contents, fatty acid distribution, and lipoprotein lipase activity were determined in 11 samples taken from the Omentum Majus of five dry Alpine goats. Samples were chosen to standardize sampling sites using geometric guide marks representative of different adipose tissue sites. Sample location explain...

journal_title：Lipids

authors： Bas P,Gallouin F,Morand-Fehr P

更新日期：1992-06-01 00:00:00

abstract：:We examined the initial transport of a long-chain unsaturated fatty acid, linoleic acid, by brush border membrane vesicles isolated from rabbit small intestine. This preparation allowed us to examine the transport of linoleic acid across the brush border membrane without the effect of the unstirred water layer or cyto...

journal_title：Lipids

authors： Ling KY,Lee HY,Hollander D

更新日期：1989-01-01 00:00:00

abstract：:Tissue and blood fatty acid compositions are used as biological markers of fatty acid intakes to improve dietary assessments. These approaches are invasive and not well accepted, particularly in infants and young children. We developed a sensitive method for the analysis of fatty acids in cheek cell glycerophospholipi...

journal_title：Lipids

authors： Klingler M,Demmelmair H,Koletzko B,Glaser C

更新日期：2011-10-01 00:00:00

abstract：:The effects of SMP-500, a novel ACAT inhibitor, on serum lipid levels, hepatic lipid secretion rate, and hepatic lipid disposition in rats were studied to clarify its lipid-lowering action. SMP-500 reduced the serum cholesterol level in a dose-dependent manner in rats fed a hypercholesterolemic diet. SMP-500 also redu...

journal_title：Lipids

authors： Ioriya K,Nishimura T,Ohashi N

更新日期：2002-04-01 00:00:00

abstract：:A cross-fostering design was used to examine the effects on brain and behavioral development in mice of pre- and/or postnatal dietary supplementation with n-3 fatty acids. Pregnant mice were fed either of two liquid diets, control (con) or experimental (exp). Each diet provided 3% of the calories in the form of n-6 fa...

journal_title：Lipids

authors： Wainwright PE,Huang YS,Bulman-Fleming B,Mills DE,Redden P,McCutcheon D

更新日期：1991-01-01 00:00:00

abstract：:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

journal_title：Lipids

authors： Masuno H,Okuda H

更新日期：1985-07-01 00:00:00

abstract：:Unsaturated free fatty acids (FFA) are able to prevent deleterious effects of saturated FFA in skeletal muscle cells although the mechanisms involved are still not completely understood. FFA act as endogenous ligands of peroxisome proliferator-activated receptors (PPAR), transcription factors regulating the expression...

journal_title：Lipids

authors： Tumova J,Malisova L,Andel M,Trnka J

更新日期：2015-10-01 00:00:00

abstract：:Acid cholesteryl ester hydrolase (CEH) activity was assayed in mononuclear cells of patients with symptomatic atherosclerosis (transient ischemic attacks, TIA) and in age-matched controls showing no evidence of atherosclerosis. The acid CEH level of TIA patients was significantly lower than that of controls (1074 +/- ...

journal_title：Lipids

authors： Yatsu FM,Hagemenas FC,Manaugh LC,Galambos T

更新日期：1980-12-01 00:00:00

abstract：:The recent discovery that the fatty acid composition of tissue phospholipids varies in a systematic manner among species has lead to the proposal that membrane fatty acid composition is an important determinant of the metabolic rate characteristic for each species. Endotherms (mammals and birds) have a basal metabolic...

journal_title：Lipids

authors： Hulbert AJ

更新日期：2007-09-01 00:00:00

abstract：:Concentrations of synthetic antioxidants butylated hydroxyanisole, butylated hydroxytoluene, and tert-butyl hydroquinone were quantified using a high-performance liquid chromatograph with spectrofluorometric detector. The antioxidants were separated and eluted on a reversed-phase column by gradient of a mixture of H2O...

journal_title：Lipids

authors： Yankah VV,Ushio H,Ohshima T,Koizumi C

更新日期：1998-11-01 00:00:00

abstract：:The purpose of this study was to compare fish intake and plasma phospholipid concentrations of n-3 fatty acids, in particular of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among representative population samples of Québecers, James Bay Cree, and Inuit of Nunavik (Canada). The relationships between the...

journal_title：Lipids

authors： Dewailly E,Blanchet C,Gingras S,Lemieux S,Holub BJ

更新日期：2003-04-01 00:00:00

abstract：:The objective of the present study was to investigate the effect of three modified milk fats with different melting profiles on fasting and postprandial lipid responses and on fecal fat content in guinea pigs. We hypothesized that the consumption of modified milk fat with a high m.p. results in reduced fasting and pos...

journal_title：Lipids

authors： Asselin G,Lavigne C,Bergeron N,Angers P,Belkacemi K,Arul J,Jacques H

更新日期：2004-10-01 00:00:00

abstract：:Barth syndrome (BTHS) is an X-linked genetic disease resulting in loss of cardiolipin (Ptd2Gro). Patients may be predisposed to hypoglycemia and exhibit increases in whole-body glucose disposal rates and a higher fat mass percentage. We examined the reasons for this in BTHS lymphoblasts. BTHS lymphoblasts exhibited a ...

journal_title：Lipids

authors： Mejia EM,Zinko JC,Hauff KD,Xu FY,Ravandi A,Hatch GM

更新日期：2017-02-01 00:00:00

abstract：:This study was designed to examine the incorporation of omega-3 (n-3) fatty acids into the immune tissues of pigs nursing fish oil-fed sows and to determine the effect of maternal dietary n-3 consumption on in vitro immune cell eicosanoid production. On day 107 of gestation, 12 sows were randomly allotted to a diet co...

journal_title：Lipids

authors： Fritsche KL,Alexander DW,Cassity NA,Huang SC

更新日期：1993-08-01 00:00:00

abstract：:A quantitative method was developed for the assay of vitamin K in human colostrum and milk. The procedure combines preparative and analytical chromatography on silica gel in a nitrogen atmosphere followed by reversed phase high performance liquid chromatography (HPLC). Two HPLC steps were used: gradient separation wit...

journal_title：Lipids

authors： Canfield LM,Hopkinson JM,Lima AF,Martin GS,Sugimoto K,Burr J,Clark L,McGee DL

更新日期：1990-07-01 00:00:00

abstract：:During germination of seeds of the gymnosperm, Pinus pinea, radioactivity from [2-14C]-mevalonate proceeded principally through the anaerobic reactions leading to squalene in the first 24 hr in both the haploid endosperm and the diploid embryo, and only with succeeding time (3-9 days) in both cases was label transferr...

journal_title：Lipids

authors： McKean ML,Nes WR

更新日期：1977-04-01 00:00:00

abstract：:Mice exposed to cold rely upon brown adipose tissue (BAT)-mediated nonshivering thermogenesis to generate body heat using dietary glucose and lipids from the liver and white adipose tissue. In this report, we investigate how cold exposure affects the PI3 K/Akt signaling cascade and the expression of genes involved in ...

journal_title：Lipids

authors： Deiuliis JA,Liu LF,Belury MA,Rim JS,Shin S,Lee K

更新日期：2010-06-01 00:00:00

abstract：:The purpose of this study was to assess changes in the degree of fatty acid unsaturation in rat liver after partial hepatectomy. This is the first study in which liver fatty acid unsaturation has been analyzed over a long period of regeneration until day 28 after operation. The relationship between changes in unsatura...

journal_title：Lipids

authors： Kishino T,Tanno M,Yamada H,Saito S,Matsumoto S

更新日期：2000-04-01 00:00:00

abstract：:The seed oil ofEuonymus verrucosus Scop., family Celastraceae, contains more than 90% 1,2-diacyl-3-acetins (monoacetotriglycerides). The constituent triglyceride acids, other than acetic, are the usual long-chain fatty acids.Thin-layer chromatography (TLC), infrared (IR) and hydrolysis with pancreatic lipase indicate ...

journal_title：Lipids

authors： Kleiman R,Miller RW,Earle FR,Wolff IA

更新日期：1967-11-01 00:00:00

abstract：:Oxidized lipoprotein(a) (oxLp(a)) is a more potent marker of atherogenesis than native Lp(a). However, the molecular mechanisms of oxLp(a) activity are not clear. Reactive oxygen species (ROS) have recently been suggested as acting as intracellular second messengers. In this study, the effects of oxLp(a) on endothelia...

journal_title：Lipids

authors： Wei DH,Zhang XL,Wang R,Zeng JF,Zhang K,Yang J,Li S,Lin XL,Jiang ZS,Wang GX,Wang Z

更新日期：2013-06-01 00:00:00

abstract：:A method for the direct preparation of fatty-acid methyl esters (FAME) was simplified for fatty-acid analysis of a single fish larva using gas chromatography (GC). The method included the isolation of a larval trunk and drying in a glass vial, followed by saponification of all the contents without prior lipid extracti...

journal_title：Lipids

authors： Matsumoto Y,Ando Y,Hiraoka Y,Tawa A,Ohshimo S

更新日期：2018-09-01 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT, EC 2.3.1.43) was assayed in vitro in plasma from normal man, rat, rabbit and dog by following the formation of 14C-cholesteryl esters subsequent to labeling the plasma with 14C-cholesterol in vitro. In all species examined, various local anesthetics were found to inhibit LCA...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1980-10-01 00:00:00

abstract：:The concentrations of the major neutral lipid and phospholipid classes in the plasma of rats bearing hepatoma 7288CTC were determined at various times after transplantation. The fatty acid composition of each lipid class was also analyzed quantitatively as tumor growth progressed. Generally, most lipid classes exhibit...

journal_title：Lipids

authors： Matocha M,Wood R

更新日期：1980-06-01 00:00:00

abstract：:Bile acid contents were determined for isolated rat hepatocytes. During the course of isolating the hepatocytes, perfusion of rat liver with buffer containing 2% albumin eluted a significant amount of bile acids. The elution was proportional to the volume of the buffer and attributable to albumin in the buffer. The is...

journal_title：Lipids

authors： Hashimoto S,Uchida K,Hirata M

更新日期：1982-03-01 00:00:00

abstract：:The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

journal_title：Lipids

authors： Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

更新日期：2019-09-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:Southern bluefin tuna (SBT, Thunnus maccoyii) aquaculture is a highly valuable industry, but research on these fish is hampered by strict catch quotas and the limited success of captive breeding. To address these limitations, we have developed a SBT cell line (SBT-E1) and here we report on fatty acid metabolism in thi...

journal_title：Lipids

authors： Scholefield AM,Schuller KA

更新日期：2014-07-01 00:00:00