The metabolism of dihomo-gamma-linolenic acid in man.

abstract：:A method is described for the determination of the positions and geometric configurations of double bonds in polyunsaturated fatty acids. The procedure consists of three steps: 1) Partial reduction of the double bonds with hydrazine under conditions which give high yields of monoenes. 2) Isolation of thecis- and thetr...

journal_title：Lipids

authors： Privett OS,Nickell EC

更新日期：1966-03-01 00:00:00

abstract：:The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphe...

journal_title：Lipids

authors： Khan AA,Husain A,Jabeen M,Mustafa J,Owais M

更新日期：2012-10-01 00:00:00

abstract：:According to the model of "response to injury," the arterial endothelium is occasionally injured in hyperlipidemia, hypertension, diabetes mellitus and in other states known as risk factors. The ensuing inflammatory response is modulated by cytokines and growth factors, among them platelet-derived growth factor (PDGF)...

journal_title：Lipids

authors： von Schacky C,Baumann K,Angerer P

更新日期：2001-01-01 00:00:00

abstract：:A patient with classic Zellweger syndrome was treated with docosahexaenoic acid ethyl ester (DHA-EE) for three months. Five other patients with Zellweger variants (four of them less than one-year-old and a five-year-old) were treated with DHA-EE until normalization of the DHA levels in erythrocytes. When arachidonic a...

journal_title：Lipids

authors： Martinez M

更新日期：1996-03-01 00:00:00

abstract：:alpha-Monoolein was prepared from glycidol and oleic acid by the regioselective opening of glycidol in the presence of an anionic resin. During the reaction, the lipochemical synthesis medium becomes enriched in monoolein, the effective emulsifying agent. This mixture can be analyzed by thin-layer chromatography coupl...

journal_title：Lipids

authors： Peyrou G,Rakotondrazafy V,Mouloungui Z,Gaset A

更新日期：1996-01-01 00:00:00

abstract：:Iron and ascorbic acid appear to be the normal catalytic components responsible for the lipid peroxidation reaction in aerobically incubated rat tissue homogenates. The amounts of each present in the catalytically-active fractions of rat liver, brain, testis, and kidney are appropriate to explain the lipid peroxidatio...

journal_title：Lipids

authors： Barber AA

更新日期：1966-03-01 00:00:00

abstract：:Concentrations of synthetic antioxidants butylated hydroxyanisole, butylated hydroxytoluene, and tert-butyl hydroquinone were quantified using a high-performance liquid chromatograph with spectrofluorometric detector. The antioxidants were separated and eluted on a reversed-phase column by gradient of a mixture of H2O...

journal_title：Lipids

authors： Yankah VV,Ushio H,Ohshima T,Koizumi C

更新日期：1998-11-01 00:00:00

abstract：:An improved headspace capillary gas chromatographic (GC) method was developed to measure the oxidative susceptibility of human red blood cell (RBC) membranes. This method analyzed volatile peroxidation products of both n-6 (hexanal and pentane) and n-3 (propanal) polyunsaturated fatty acids. Oxidative susceptibility t...

journal_title：Lipids

authors： Frankel EN,Tappel AL

更新日期：1991-06-01 00:00:00

abstract：:The schweinfurthins have potent antiproliferative activity in multiple glioblastoma multiforme (GBM) cell lines; however, the mechanism by which growth is impeded is not fully understood. Previously, we demonstrated that the schweinfurthins reduce the level of key isoprenoid intermediates in the cholesterol biosynthet...

journal_title：Lipids

authors： Kuder CH,Weivoda MM,Zhang Y,Zhu J,Neighbors JD,Wiemer DF,Hohl RJ

更新日期：2015-12-01 00:00:00

abstract：:The evaluation of antioxidant activity in vivo is difficult. In this study, the effects of dietary natural and synthetic antioxidants on the lipid peroxidation in mice were assessed using a biomarker, total hydroxyoctadecadienoic acid (tHODE). Biological samples such as plasma, erythrocytes, and tissues were first red...

journal_title：Lipids

authors： Yoshida Y,Hayakawa M,Habuchi Y,Itoh N,Niki E

更新日期：2007-05-01 00:00:00

abstract：:A procedure for the preparation of specific molecular species of D-erythro-lactosylceramide involving deacylation and reacylation of lactosylceramide prepared from bovine brain gangliosides is described. Lactosylceramide was N-deacylated by alkaline hydrolysis and the resulting four lysolactosylceramides, which contai...

journal_title：Lipids

authors： Kadowaki H,Grant MA

更新日期：1994-10-01 00:00:00

abstract：:Policosanol is a poorly absorbed nutritional supplement used primarily for cholesterol management. Findings from previous trials evaluating the effects of policosanol are mixed with early data reporting positive lipid effects while more recent studies indicate negligible efficacy. We hypothesized that re-formulating p...

journal_title：Lipids

authors： Backes JM,Gibson CA,Ruisinger JF,Moriarty PM

更新日期：2011-10-01 00:00:00

abstract：:Dietary lipids, in particular unsaturated fat, promote the development of many experimental tumors. However, no mechanisms to fully explain these effects have been elucidated. Recent reports, which we summarize here, suggest a role for gap junction-mediated intercellular communication in the process of tumor promotion...

journal_title：Lipids

authors： Aylsworth CF,Welsch CW,Kabara JJ,Trosko JE

更新日期：1987-06-01 00:00:00

abstract：:The source of free fatty acids (FFA) and the pathways contributing to the accumulation of neutral fats in livers of rats fed a cholesterol-enriched diet were investigated in this report. Supplementation with 1% cholesterol in the diet for four weeks resulted in hepatomegaly in the rats. The contents of cholesterol and...

journal_title：Lipids

authors： Liu CH,Huang MT,Huang PC

更新日期：1995-06-01 00:00:00

abstract：:Tetramethylammonium hydroxide has been used in the extraction and pyrolysis methylation of the carboxylic acids produced by periodate-permanganate oxidation of monounsaturated fatty acid methyl esters. This modification of the von Rudloff procedure allows rapid determination of double-bond positions and analysis of mi...

journal_title：Lipids

authors： Downing DT,Greene RS

更新日期：1968-01-01 00:00:00

abstract：:The objective of the present study was to investigate the effect of three modified milk fats with different melting profiles on fasting and postprandial lipid responses and on fecal fat content in guinea pigs. We hypothesized that the consumption of modified milk fat with a high m.p. results in reduced fasting and pos...

journal_title：Lipids

authors： Asselin G,Lavigne C,Bergeron N,Angers P,Belkacemi K,Arul J,Jacques H

更新日期：2004-10-01 00:00:00

abstract：:Microsomal and myelin membrane fractions were prepared from the brains of warm-adapted (room temperature) and hibernating Syrian Hamsters (Mesocricetus auratus). Ethanolamineglycerophospholipids were isolated and subjected to a fractionation scheme to separate the fatty acids of the plasmenylethanolamine and the phosp...

journal_title：Lipids

authors： Blaker WD,Moscatelli EA

更新日期：1979-12-01 00:00:00

abstract：:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

journal_title：Lipids

authors： Masuno H,Okuda H

更新日期：1985-07-01 00:00:00

abstract：:In the wild, nutrients from plants provide for the requirements of all herbivores and ultimately all animals, yet little work has been published on how such nutrients change with environmental conditions. Plant lipids are nutritionally important for browsing mammals, initially with respect to taste and palatability, b...

journal_title：Lipids

authors： Davidson BC

更新日期：1998-01-01 00:00:00

abstract：:Red blood cell (RBC) fatty acid (FA) patterns have been shown to predict risk for cardiovascular and other chronic diseases. As part of a project analyzing RBC samples from the Women's Health Initiative Memory Study (WHIMS) we observed implausibly low levels of highly unsaturated fatty acids (HUFA) suggestive of degra...

journal_title：Lipids

authors： Pottala JV,Espeland MA,Polreis J,Robinson J,Harris WS

更新日期：2012-09-01 00:00:00

abstract：:The effects of n-3 fatty acids on plasma lipids, lipoproteins and apoproteins have usually been studied in humans after feeding of purified fish oil. This study describes the effect of a natural diet, containing salmon as the source of n-3 fatty acids, on these parameters as compared to a diet very low in n-3 fatty ac...

journal_title：Lipids

authors： Lindgren FT,Adamson GL,Shore VG,Nelson GJ,Schmidt PC

更新日期：1991-02-01 00:00:00

abstract：:The permeability of an N-oleoyldihydrosphingomyelin bilayer against glycerol was similar to that of a bilayer of phosphatidylcholine with identical effective hydrophobic chain length. Cholesterol at 1:1 molar ratio reduced the permeability, and also reduced the energy of activation of glycerol penetration, an effect n...

journal_title：Lipids

authors： Tirri LJ,Ayengar NK,Lipton LC,Chatterjie N,Brockerhoff H

更新日期：1978-04-01 00:00:00

abstract：:CLA has a range of biological properties, including effects on lipid metabolism and body composition in experimental animals. The prevalent isomer of CLA found in the human diet is 9c,11 t-CLA, and it is predominantly found in products containing fat from ruminant animals. This study investigated the effect of dietary...

journal_title：Lipids

authors： Hayman A,MacGibbon A,Pack RJ,Rutherfurd K,Green JH

更新日期：2002-07-01 00:00:00

abstract：:Previous studies show that long term variations in dietary fat consumption impact circulating fatty acid ethanolamide (FAE) concentrations, however, few studies have investigated short term effects of dietary fat feeding on FAE levels. The trial's objective was to explore the effect of acute feeding of varying amounts...

journal_title：Lipids

authors： Olatinsu AO,Sihag J,Jones PJH

更新日期：2017-11-01 00:00:00

abstract：:The oxidation of free DHA, DHA mixed with PC, and DHA incorporated into PC, PE, or TG was evaluated to determine which lipid provided DHA with the best protection against oxidation. DHA was either situated at the sn-1 position, sn-2 position, or both positions of the phospholipid, whereas the TG contained DHA at all p...

journal_title：Lipids

authors： Lyberg AM,Fasoli E,Adlercreutz P

更新日期：2005-09-01 00:00:00

abstract：:A 24-hr pretreatment of cultured human fibroblasts with trifluoperazine induced a marked increase in incorporation of saturated (stearic, palmitic) and unsaturated (oleic, arachidonic) fatty acids into phospholipids (1.5- to 2-fold for 5.10(-5) M trifluoperazine). Concomitantly, incorporation into cholesteryl esters w...

journal_title：Lipids

authors： Mazière C,Mazière JC,Mora L,Auclair M,Polonovski J

更新日期：1988-05-01 00:00:00

abstract：:A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...

journal_title：Lipids

authors： Siebert BD,Kruk ZA,Davis J,Pitchford WS,Harper GS,Bottema CD

更新日期：2006-04-01 00:00:00

abstract：:Trichloroacetic acid (TCA)-phosphotungstic acid (PTA) precipitation has been used as a faster procedure than dialysis for the isolation of gangliosides, but the TCA-PTA treatment causes striking abnormalities in the thin layer chromatographic mobilities of the gangliosides. However, a normal chromatographic pattern ca...

journal_title：Lipids

authors： Seyfried TN,Weber EJ,Yu RK

更新日期：1977-11-01 00:00:00

abstract：:[1-14C]alpha-Linolenic acid was incubated with a particulate fraction of homogenate of leaves of the meadow buttercup (Ranunculus acris L.). The main product was a divinyl ether fatty acid, which was identified as 12-[1'(Z),3'(Z)-hexadienyloxy]-9(Z),11(E)-dodecadienoic acid. Addition of glutathione peroxidase and redu...

journal_title：Lipids

authors： Hamberg M

更新日期：1998-11-01 00:00:00

abstract：:The use of the organic cosolvents tetrahydrofuran and dimethylsulfoxide was found to be unsuitable for prostate tumor cell cultures because of solvent cytotoxicity and the poor solubility and instability of lycopene. For example, the half-life of lycopene in organic/aqueous solution was found to be less than 2 h. Ther...

journal_title：Lipids

authors： Xu X,Wang Y,Constantinou AI,Stacewicz-Sapuntzakis M,Bowen PE,van Breemen RB

更新日期：1999-10-01 00:00:00