Increased hepatic delta 6-desaturase activity with growth hormone expression in the MG101 transgenic mouse.

abstract：:A pilot study was undertaken to determine if moderate changes in linoleate (18:2 omega 6) intake would modulate the prostaglandin E turnover concurrently with, or independently of, changes in the plasma prostaglandin (PG) precursor levels. Four adult male volunteers in good health were fed two controlled diets contain...

journal_title：Lipids

authors： Ferretti A,Judd JT,Marshall MW,Flanagan VP,Roman JM,Matusik EJ Jr

更新日期：1985-05-01 00:00:00

abstract：:According to the model of "response to injury," the arterial endothelium is occasionally injured in hyperlipidemia, hypertension, diabetes mellitus and in other states known as risk factors. The ensuing inflammatory response is modulated by cytokines and growth factors, among them platelet-derived growth factor (PDGF)...

journal_title：Lipids

authors： von Schacky C,Baumann K,Angerer P

更新日期：2001-01-01 00:00:00

abstract：:Among many factors, elevated lipids and lipid peroxide levels in blood are major risk factors in the development of cardiovascular disease in diabetic patients. This study has examined whether oral supplementation of vitamin E, an antioxidant, has any effect on blood lipid peroxidation products (LP) and lipid profile ...

journal_title：Lipids

authors： Jain SK,McVie R,Jaramillo JJ,Palmer M,Smith T,Meachum ZD,Little RL

更新日期：1996-03-01 00:00:00

abstract：:Previous studies from our laboratory have shown that retinitis pigmentosa (RP), a family of hereditary retinal degenerations, is often accompanied by abnormal levels of cholesterol or polyunsaturated fatty acids. The requirement of the retina for n-3 fatty acids is well known, and a defect in the supply of these lipid...

journal_title：Lipids

authors： Huq L,McLachlan T,Hammer HM,Bedford D,Packard CJ,Shepherd J,Converse CA

更新日期：1993-11-01 00:00:00

abstract：:Cholesterol absorption is frequently determined using the plasma dual stable-isotope ratio method (PDSIRM). However, this method involves intravenous injection of stable-isotope-labeled cholesterol with simultaneous oral administration of differently labeled cholesterol, which results in high study costs and involves ...

journal_title：Lipids

authors： Wang Y,Vanstone CA,Parsons WD,Jones PJ

更新日期：2004-01-01 00:00:00

abstract：:Meadowfoam oil is unusual because over 95% of the fatty acids are 20- and 22-carbon aliphatic acids with cis double bonds located principally at the 5- and/or 13-position. Since little information is available on the metabolism of the 5c-20:1 and 5c,13c-22:2 fatty acids, an exploratory study in mice was conducted to i...

journal_title：Lipids

authors： Emken EA,Adlof RO,Abraham S

更新日期：1991-09-01 00:00:00

abstract：:Observational evidence suggests that in populations consuming low levels of n-3 highly unsaturated fatty acids, women have higher blood levels of docosahexaenoic acid (DHA; 22:3n-6) as compared with men. Increased conversion of alpha-linolenic acid (ALA; 18:3n-3) to DHA by females has been confirmed in fatty acid stab...

journal_title：Lipids

authors： Kitson AP,Stroud CK,Stark KD

更新日期：2010-03-01 00:00:00

abstract：:Rat hepatocytes in monolayer culture were utilized to determine if the decrease in glucose-6-phosphate dehydrogenase (G6PD) activity resulting from the ingestion of fat can be mimicked by the addition of fatty acids to a chemically, hormonally defined medium. G6PD activity in cultured hepatocytes was induced several-f...

journal_title：Lipids

authors： Salati LM,Adkins-Finke B,Clarke SD

更新日期：1988-01-01 00:00:00

abstract：:The separation of lecithin derivatives based on their fatty acid substituents has been investigated. Several synthetic and natural lecithins were converted to their corresponding dimethylphosphatidates by hydrolysis with phospholipase D (phosphatidylcholine phospholipase D (phosphatidylcholine phosphatidohydrolase, EC...

journal_title：Lipids

authors： Wurster CF Jr,Copenhaver JH Jr

更新日期：1966-11-01 00:00:00

abstract：:Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted five- or six-carbon-membered ring structures. Some earlier studies have suggested that some of these molecules could be metabolized and detoxified, but so far, nei...

journal_title：Lipids

authors： Desmarais A,Pujos-Guillot E,Lyan B,Martin JF,Leblanc N,Angers P,Sébédio JL

更新日期：2015-04-01 00:00:00

abstract：:Changes in a number of morphological and biochemical parameters were observed in genetically obese Zucker rats and in lean controls between 3 and 58 weeks of age. By 3 weeks, the genetically obese rats had higher proportional (wt/100 g body wt) and absolute amounts of adipose tissue, hyperlipemia affecting all the lip...

journal_title：Lipids

authors： Bach A,Schirardin H,Bauer M,Schaeffer A,Weryha A

更新日期：1981-11-01 00:00:00

abstract：:Linoleic acid was efficiently converted into the two major components of conjugated linoleic acid, 9Z,11E-octadecadienoic (1a) and 10E,12Z-octadecadienoic acid (1b) using either the superbase (n-butyllithium/potassium tert-butoxide) or by simply refluxing with KOH in 1-butanol. In turn, 1a and 1b were separated from e...

journal_title：Lipids

authors： Chen CA,Lu W,Sih CJ

更新日期：1999-08-01 00:00:00

abstract：:Several experimental approaches were used to determine whether rat liver and testes express an acyl-CoA-dependent delta8 desaturase. When [1-14C]5,11,14-eicosatrienoic acid was injected via the tail vein, or directly into testes, it was incorporated into liver and testes phospholipids, but it was not metabolized to ot...

journal_title：Lipids

authors： Chen Q,Yin FQ,Sprecher H

更新日期：2000-08-01 00:00:00

abstract：:The aim of the present work was to study the effect of season on phospholipids and triacylglycerols (TAG) of mantle and tentacles of female and male wild Sepia officinalis. The identified phospholipids were phosphatidylethanolamine (PtdEtn), phosphatidylcholine (PtdCho), phosphatidylserine (PtdSer), and phosphatidylin...

journal_title：Lipids

authors： Tir M,El Cafsi I,Ammar RB,Mejri H,Tlili N,El Cafsi M

更新日期：2019-02-01 00:00:00

abstract：:A novel phospholipid containing a chromanol structure at its polar head group was synthesized from egg yolk phosphatidylcholine and 2,5,7,8-tetramethyl-6-hydroxy-2-(hydroxyethyl)chroman by transphosphatidylation catalyzed by phospholipase D from Streptomyces lydicus. The structure of the product synthesized was shown ...

journal_title：Lipids

authors： Koga T,Nagao A,Terao J,Sawada K,Mukai K

更新日期：1994-02-01 00:00:00

abstract：:Hydrolysis of symmetrical acetylenic TG of type AAA [viz., glycerol tri-(4-decynoate), glycerol tri-(6-octadecynoate), glycerol tri-(9-octadecynoate), glycerol tri-(10-undecynoate), and glycerol tri-(13-docosynoate)] in the presence of eight microbial lipases was studied. Novozyme 435 (Candida antarctica), an efficien...

journal_title：Lipids

authors： Jie MS,Fua X,Lau MM,Chye ML

更新日期：2002-10-01 00:00:00

abstract：:Liver fatty-acid-binding protein (FABP1, L-FABP) is the major cytosolic binding/chaperone protein for both precursor arachidonic acid (ARA) and the endocannabinoid (EC) products N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). Although FABP1 regulates hepatic uptake and metabolism of ARA, almost not...

journal_title：Lipids

authors： McIntosh AL,Huang H,Landrock D,Martin GG,Li S,Kier AB,Schroeder F

更新日期：2018-06-01 00:00:00

abstract：:trans-10,cis-12-CLA (t10,c12-CLA) inhibits lipid deposition in adipose tissue of many species, but it also enhances lipid deposition in liver. We evaluated effects of dietary t10,c12-CLA content and gender on carcass composition, FA profile of selected tissues, and expression of FA synthase (FAS) and stearoyl-CoA desa...

journal_title：Lipids

authors： Viswanadha S,McGilliard ML,Herbein JH

更新日期：2006-08-01 00:00:00

abstract：:The concentrations of nonesterified fatty acids and glycerol in rat parametrial adipose tissue increased at peak lactation. Adipose tissue from lactating rats showed higher rates of release of nonesterified fatty acids and glycerol when incubated in vitro than did tissue from nonlactating rats, but there was a substan...

journal_title：Lipids

authors： Smith RW,Walsh A

更新日期：1976-05-01 00:00:00

abstract：:The bile acid pool was found to be ca. 50 mumoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 mumoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except...

journal_title：Lipids

authors： Fisher MM,Kakis G,Yousef IM

更新日期：1976-02-01 00:00:00

abstract：:Commercial fish oils and foods containing fish may contain trans and/or isomerized fatty acids (FA) produced during processing or as part of prepared foods. The current American Oil Chemists' Society (AOCS) official method for marine oils (method Ce 1i-07) is based on separation by use of poly(ethylene glycol) (PEG) c...

journal_title：Lipids

authors： Santercole V,Delmonte P,Kramer JK

更新日期：2012-03-01 00:00:00

abstract：:The effects of feeding CLA to hens on newly hatched chick hepatic and carcass lipid content, liver TAG accumulation, and FA incorporation in chick tissues such as liver, heart, brain, and adipose were studied. These tissues were selected owing to their respective roles in lipid assimilation (liver), as a major oxidati...

journal_title：Lipids

authors： Cherian G,Ai W,Goeger MP

更新日期：2005-02-01 00:00:00

abstract：:The all-cis-5,9,12-heptadecatrienoic acid was identified in the cellular slime mold Polysphondylium pallidum. The structural elucidation was accomplished by capillary gas chromatography, argentation thin-layer chromatography, and gas chromatography/mass spectrometry. This fatty acid has not been reported previously. ...

journal_title：Lipids

authors： Saito T,Ochiai H

更新日期：1996-04-01 00:00:00

abstract：:Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...

journal_title：Lipids

authors： Bhatt DP,Rosenberger TA

更新日期：2014-07-01 00:00:00

abstract：:Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the NOX subunits in an uncontrolled manner. Therefore, targeting neutrophil subunits would repre...

journal_title：Lipids

authors： Liu M,Boussetta T,Makni-Maalej K,Fay M,Driss F,El-Benna J,Lagarde M,Guichardant M

更新日期：2014-01-01 00:00:00

abstract：:In vivo intestinal perfusion was used to follow the absorption of three different choline glycerophospholipids (CGP) in guinea pig. These included 1-[3H]palmitoyl-2-acyl-sn-glycero-3-phosphocholine (diacyl-GPC), 1-[3H]-O-hexadecyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) and 1,2-di-O-hexadecyl-sn-glycero-3-p...

journal_title：Lipids

authors： Diagne A,Mitjavila S,Fauvel J,Chap H,Douste-Blazy L

更新日期：1987-01-01 00:00:00

abstract：:Membrane lipids of photosynthetic organisms consist of glycerophospholipids and glyceroglycolipids. We investigated a method for the simultaneous quantitative analysis of neutral and acidic lipids using HPLC-ELSD, and quantified monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and sulfoquinovosyl...

journal_title：Lipids

authors： Yunoki K,Sato M,Seki K,Ohkubo T,Tanaka Y,Ohnishi M

更新日期：2009-01-01 00:00:00

abstract：:Hepatocytes isolated from rainbow trout fed on diets containing either fish oil or olive oil were incubated with individual odd-chain length unsaturated fatty acids (19:1n-9, 19:2n-6, 19:3n-3, 21:2n-6, 21:3n-6, 21:4n-6, 21:3n-3, and 21:5n-3) to examine whether these fatty acids were substrates for modification by desa...

journal_title：Lipids

authors： Rodríguez C,Henderson RJ,Porter AE,Dick JR

更新日期：1997-06-01 00:00:00

abstract：:In an attempt to clarify the mechanism of lipid accumulation inMortierella ramanniana var.angulispora, diacylglycerol acyltransferase (DGAT) in the membrane fraction from this fungus was characterized. The enzyme had an optimum pH of 7.0-7.5, and enzyme activity was blocked by SH-reagents. Metal ions were not essentia...

journal_title：Lipids

authors： Kamisaka Y,Yokochi T,Nakahara T,Suzuki O

更新日期：1993-07-01 00:00:00

abstract：:The diurnal variation in lysosomal acid cholesteryl ester hydrolase (Acid CEH), (EC 3.1.1.13) has been examined in fed, fasted and adrenalectomized rats. The Acid CEH activity of normal rat liver exhibits a diurnal rhythm with maxima at 06.00 hours and minima at 18.00 hours, but such a rhythm was not observed in splee...

journal_title：Lipids

authors： Tanaka M,Yonekura R,Iio T,Tabata T

更新日期：1985-01-01 00:00:00