Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate.

abstract：:The synthesis of phosphoglycerides is reviewed. Emphasis is placed upon precursor and intermediate compounds, phosphatidic acid, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, monoacylphosphoglycerides, purification and proof of structure. Suggestions are made for large scale synthesis of phosph...

journal_title：Lipids

authors： Jensen RG,Gordon DT

更新日期：1972-09-01 00:00:00

abstract：:A simple method is described for the preparation of [6,7,7(-2)H3] sterols and steroids. The synthesis starts with a Δ(5)-sterol or steroid and involves preparation of the 6-oxo-3α,5α-cyclosteroid, base exchange in the presence of deuterium oxide to introduce two deuteriums at the C-7 position and sodium borodeuteride ...

journal_title：Lipids

authors： Goad LJ,Breen MA,Rendell NB,Rose ME,Duncan JN,Wade AP

更新日期：1982-12-01 00:00:00

abstract：:There have been a limited number of studies investigating surfactant lipid changes in lung with trace elements. The present investigation was designed to examine the effect of moderate zinc deficiency on the lipid metabolism in rat lung. We also evaluated whether zinc deficiency, which is a wide-spread problem, could ...

journal_title：Lipids

authors： Gomez NN,Ojeda MS,Gimenez MS

更新日期：2002-03-01 00:00:00

abstract：:Fatty acid synthetase purified (20 times) from lactating bovine mammary tissue had an approximate mot wt of 485,000. The enzyme had a high content of acidic and hydrophobic amino acid residues; 62±4 sulhydryl groups and one 4' phosphopantetheine residue/mole of enzyme. The enzyme was relatively stable when stored (3 m...

journal_title：Lipids

authors： Kinsella JE,Bruns D,Infante JP

更新日期：1975-04-01 00:00:00

abstract：:Selected aspects of total parenteral nutrition in man are reviewed with emphasis on carbohydrate, lipid, and hormonal interactions. In an experiment to test for the essentiality of a specific amino acid, a normal adult man received all major and minor nutrients, except lipids, by intravenous alimentation for 48 days. ...

journal_title：Lipids

authors： Wixom RL,Sheng YB,Anderson HL,Yamanaka WK,Terry BE

更新日期：1976-04-01 00:00:00

abstract：:The 4-monomethylsterol and 4,4-dimethylsterol fractions were separated from the unsaponifiables of 20 vegetable oils by preparative thin layer chromatography, and their compositions were determined by gas liquid chromatography. Tentative identification of the individual components of these fractions was carried out by...

journal_title：Lipids

authors： Jeong TM,Itoh T,Tamura T,Matsumoto T

更新日期：1975-10-01 00:00:00

abstract：:Microtiter plate methods were developed for the enzymatic determination of serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG), and for the turbidometric determination of apolipoproteins. The micromethods resulted in accurate, precise values that were in good agreement with...

journal_title：Lipids

authors： Shireman RB,Durieux J

更新日期：1993-02-01 00:00:00

abstract：:Salmon farmers are currently using high-energy feeds containing up to 35% fat; the fish's capability of fully utilizing these high-energy feeds has received little attention. Carnitine is an essential component in the process of mitochondrial fatty acid oxidation and, with the cooperation of two carnitine palmitoyltra...

journal_title：Lipids

authors： Frøyland L,Madsen L,Eckhoff KM,Lie O,Berge RK

更新日期：1998-09-01 00:00:00

abstract：:The biosynthesis of 3R-hydroxy-5Z, 8Z, 11Z,14Z-eicosatetraenoic acid (3R-HETE) from arachidonic acid (20:4n-6) by the hyphal-forming yeast, Dipodascopsis uninucleata, in cell-free enzyme extracts required CoASH, ATP, NAD+ and Mg2+; 3R-HETE was present as the CoA derivative in enzyme extracts and its biosynthesis was a...

journal_title：Lipids

authors： Fox SR,Hamberg M,Friend J,Ratledge C

更新日期：2000-11-01 00:00:00

abstract：:Triacylglycerols containing linoleate and linolenate found in vegetable oils were synthesized in gram quantities for oxidation studies. Two acylation methods were examined to convert diacylglycerols or monoacylglycerols to the desired triacylglycerols. Acylations with fatty acid and 1,1'-dicyclohexylcarbodiimide in th...

journal_title：Lipids

authors： Awl RA,Frankel EN,Weisleder D

更新日期：1989-10-01 00:00:00

abstract：:Soy isoflavones may impede atherogenic processes associated with cardiovascular disease. Research suggests that the postprandial generation of TG-rich remnants contributes to the development of atherosclerosis. The purpose of the current study was to determine if 39 g soy (85 mg aglycone isoflavones, treatment) compar...

journal_title：Lipids

authors： Campbell CG,Brown BD,Dufner D,Thorland WG

更新日期：2006-03-01 00:00:00

abstract：:The composition of the glycosphingolipids of the human gastrointestinal tract was studied. The major neutral glycosphingolipids were ceramide monohexosides (e.g., GalCer, GlcCer), LacCer, Gb3Cer, Gb4Cer and more polar ones with more than four sugars, whereas neither Gg3Cer nor Gg4Cer were present. The acidic glycosphi...

journal_title：Lipids

authors： Natomi H,Saitoh T,Sugano K,Iwamori M,Fukayama M,Nagai Y

更新日期：1993-08-01 00:00:00

abstract：:Lifibrol, a new hypocholesterolemic agent with activity in humans, was examined in normal rats for its short-term and long-term effects on lipid homeostasis. Cholesterol (Chol) synthesis inhibition by lifibrol was demonstrated in vitro in liver minces from normal rats by following [1-14C]acetate ([14C]Ac) and DL-[2-14...

journal_title：Lipids

authors： Bell FP,St John LC

更新日期：1993-12-01 00:00:00

abstract：:Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects consuming a low fat (20% of calories) diet consisting of fatty acids...

journal_title：Lipids

authors： Sampugna J,Light L,Enig MG,Jones DY,Judd JT,Lanza E

更新日期：1988-02-01 00:00:00

abstract：:An experiment examined delta9 desaturase activity and FA composition in subcutaneous adipose tissue in two differing breeds of cattle. Jersey-sired cattle had significantly higher rates of desaturase activity than Limousin-sired cattle (1.55 vs. 0.75 nmol/mg protein/min). This difference was also demonstrated by a low...

journal_title：Lipids

authors： Siebert BD,Pitchford WS,Kruk ZA,Kuchel H,Deland MP,Bottema CD

更新日期：2003-05-01 00:00:00

abstract：:Fecal bile acid and neutral sterol patterns were studied in eight healthy adult volunteers who were challenged with Vibrio cholerae classical Ogawa 395 strain in the course of vaccine development studies. Bacterial 7 alpha-dehydroxylation of cholic and chenodeoxycholic acids was not altered during experimentally induc...

journal_title：Lipids

authors： Huang CT,Levine MM,Daoud GS,Nalin DR,Nichols BL

更新日期：1982-09-01 00:00:00

abstract：:This study was conducted to investigate the effects of dietary cyclic fatty acid monomers (CFAM), contained in heated fat from a commercial deep-fat frying operation, on rat liver enzyme activity. A partially hydrogenated soybean oil (PHSBO) used 7 d (7-DH) for frying foodstuffs, or 0.15% methylated CFAM diets was fed...

journal_title：Lipids

authors： Lamboni C,Sébédio JL,Perkins EG

更新日期：1998-07-01 00:00:00

abstract：:This study evaluated the effects of conjugated linoleic acids (CLA) on tissue fatty acid composition and ex vivo prostaglandin E2 (PGE2) production in rats given diets varying in n-6 and n-3 fatty acids. Four groups of rats were given a basal semipurified diet (AIN-93G) containing 70 g/kg of added fat for 42 d. The fa...

journal_title：Lipids

authors： Li Y,Watkins BA

更新日期：1998-04-01 00:00:00

abstract：:The suppression of plasma very low density lipoprotein (VLDL) triglyceride levels by dietary fish oils rich in polyunsaturated n-3 fatty acids has been attributed to decreased hepatic VLDL secretion. To investigate the effect of n-3 fatty acids on lipid metabolism and VLDL secretion in a tissue culture system, we incu...

journal_title：Lipids

authors： Benner KG,Sasaki A,Gowen DR,Weaver A,Connor WE

更新日期：1990-09-01 00:00:00

abstract：:Plasma fatty acid (FA) composition is known to be an indicator of dietary fat quality, but the associations of other dietary factors with plasma FA composition remain unknown in children. We investigated the cross-sectional associations of food consumption with the proportions of FA and estimated desaturase activities...

journal_title：Lipids

authors： Venäläinen T,Schwab U,Ågren J,de Mello V,Lindi V,Eloranta AM,Kiiskinen S,Laaksonen D,Lakka TA

更新日期：2014-05-01 00:00:00

abstract：:The effects of conjugated linoleic acid (CLA) on the levels of chemical mediators in peritoneal exudate cells, spleen and lung, and the concentration of immunoglobulins in mesenteric lymph node and splenic lymphocytes and in serum were examined in rats. After feeding diets containing either 0 (control), 0.5 or 1.0% CL...

journal_title：Lipids

authors： Sugano M,Tsujita A,Yamasaki M,Noguchi M,Yamada K

更新日期：1998-05-01 00:00:00

abstract：:Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...

journal_title：Lipids

authors： Adachi J,Ueno Y,Miwa A,Asano M,Nishimura A,Tatsuno Y

更新日期：1997-11-01 00:00:00

abstract：:The effect of Rauscher Leukemia Virus (MuLV-R) infection on the lipid composition of mouse spleen from BALB/c mice was investigated. Drastic changes in the lipid composition of the spleen as a result of tumor growth induced by the virus could be demonstrated at 21 days after infection. The molar ratio of cholesterol t...

journal_title：Lipids

authors： Montfoort A,Boere WA,Griensven LJLDV

更新日期：1976-11-01 00:00:00

abstract：:Stimulation of platelets induces a rapid release of arachidonate from specific phospholipids and subsequent remodeling of arachidonate-containing phospholipids. This process is accompanied by transformation of released arachidonate by cyclooxygenase and lipoxygenase enzymes. We addressed the question of whether the cy...

journal_title：Lipids

authors： Chevy F,Wolf C,Colard O

更新日期：1991-12-01 00:00:00

abstract：:This study compared (i) the relative effects of long-chain triglycerides (LCT) and medium-chain triglycerides (MCT), (ii) the influence of amount of MCT, and (iii) the impact of medium-chain fatty acid position, on plasma and lymphatic triglycerides and portal vein free fatty acids. The animals were fed approximately ...

journal_title：Lipids

authors： You YQ,Ling PR,Qu Z,Bistrian BR

更新日期：1998-03-01 00:00:00

abstract：:Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

journal_title：Lipids

authors： Burger WC,Qureshi AA,Prentice N,Elson CE

更新日期：1982-12-01 00:00:00

abstract：:The minimum requirement of linoleic acid to prevent effects of dietary C18 trans fatty acids on eicosanoid biosynthesis in rats was assessed. In a first experiment, six groups of animals were fed diets with a high content of trans fatty acids [20% of energy (en%)], and increasing amounts of linoleic acid (0.4 to 7.1 e...

journal_title：Lipids

authors： Zevenbergen JL,Haddeman E

更新日期：1989-06-01 00:00:00

abstract：:After intravenous injection of liposomes prepared from egg yolk phospholipids into rabbits, the phospholipids were readily assimilated by the lipoproteins, and there were increases in the circulating levels of cholesterol and phospholipids. The increases in cholesterol level were mainly due to increases of free choles...

journal_title：Lipids

authors： Mendez AJ,He JL,Huang HS,Wen SR,Hsia SL

更新日期：1988-10-01 00:00:00

abstract：:Some studies focused on the effect of the dietary glycemic index on lipoproteins and apolipoproteins in adults; however, little evidence exists among adolescents regarding the effect of a low glycemic index (LGI) diet on apolipoproteins and lipoprotein (a) (Lpa). This study was conducted to evaluate the effect of an L...

journal_title：Lipids

authors： Rouhani MH,Kelishadi R,Hashemipour M,Esmaillzadeh A,Azadbakht L

更新日期：2013-12-01 00:00:00

abstract：:Lipids from bovine optic nerve were analyzed. The total content of 16.5% by weight included 27.2% nonpolar lipids, 26.1% glycolipids, and 46.7% phospholipids by weight. Free cholesterol was the major component of the nonpolar lipid fraction. The cerebrosides, 73.5% of total glycolipids, were separated by thin layer ch...

journal_title：Lipids

authors： Das SK,Steen ME,McCullough MS,Bhattacharyya DK

更新日期：1978-10-01 00:00:00