Changes in the cholesterol and phospholipid content of mouse spleen after Raucscher leukemia virus infection.

Abstract:

:The effect of Rauscher Leukemia Virus (MuLV-R) infection on the lipid composition of mouse spleen from BALB/c mice was investigated. Drastic changes in the lipid composition of the spleen as a result of tumor growth induced by the virus could be demonstrated at 21 days after infection. The molar ratio of cholesterol to phospholipids was found to be low, while a shift within the choline containing phospholipid classes resulted into a lower sphingomyelin and a higher phosphatidyl choline content of the MuLV-R infected spleen. The cholesterol ester content increased more than two-fold during tumor growth, and shifts in the fatty acid patterns of the lipids were demonstrated.

journal_name

Lipids

journal_title

Lipids

authors

Montfoort A,Boere WA,Griensven LJLDV

doi

10.1007/BF02533406

subject

Has Abstract

pub_date

1976-11-01 00:00:00

pages

798-801

issue

11

eissn

0024-4201

issn

1558-9307

journal_volume

11

pub_type

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