A unique pool of free arachidonate serves as substrate for both cyclooxygenase and lipoxygenase in platelets.

abstract：:The purpose of these experiments was to study the uptake and metabolism of exogenous triglyceride in the isolated perfused rabbit heart. When infused into the rabbit heart, [9,10-3H(N)]triolein was retained and incorporated into a lipid fraction that had the chromatographic mobility of authentic triolein. Incorporatio...

journal_title：Lipids

authors： Weis MT,Palazzo AJ,Williams JL Jr,Malik KU

更新日期：1990-08-01 00:00:00

abstract：:The fatty acid composition of the membrane phospholipids phosphatidylcholine (PC) and phosphatidylethanolamine in insulin-sensitive Type I (soleus) and insulin-resistant Type II (EDL) muscle is not known. In the present studies, soleus and EDL muscles were removed from 250-300 g Sprague-Dawley rats, and the fatty acid...

journal_title：Lipids

authors： Blackard WG,Li J,Clore JN,Rizzo WB

更新日期：1997-02-01 00:00:00

abstract：:The major component of cutin from the fruit of both tomato and papaya, dihydroxypalmitate, is shown to have plain positive rotation and is, therefore, assigned L configuration in analogy to other known hydroxy fatty acids. ...

journal_title：Lipids

authors： Espelie KE,Kolattukudy PE

更新日期：1978-11-01 00:00:00

abstract：:The gut microbiota is proposed as a "metabolic organ" involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on host metabolism and gut microbiota. In the present study, we examined the ...

journal_title：Lipids

authors： Shang Y,Khafipour E,Derakhshani H,Sarna LK,Woo CW,Siow YL,O K

更新日期：2017-06-01 00:00:00

abstract：:Biosynthesis of peripheral nerve cholesterol was investigated by the in vivo and in vitro incorporation of [1-14C]-acetate into sciatic endoneurium of normal rats during development, degeneration and regeneration. Labeled sterols were rapidly formed (less than 10 min) within the endoneurial portion of sciatic nerve af...

journal_title：Lipids

authors： Yao JK

更新日期：1988-09-01 00:00:00

abstract：:Phospholipids are integral constituents of the milk fat globule membranes and they play a central role in infants' immune and inflammatory responses. A methodology employing liquid chromatography coupled with evaporative light scattering detector has been optimized and validated to quantify the major phospholipids cla...

journal_title：Lipids

authors： Giuffrida F,Cruz-Hernandez C,Flück B,Tavazzi I,Thakkar SK,Destaillats F,Braun M

更新日期：2013-10-01 00:00:00

abstract：:In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that...

journal_title：Lipids

authors： Seet EL,Yee JK,Jellyman JK,Han G,Ross MG,Desai M

更新日期：2015-06-01 00:00:00

abstract：:Dyslipoproteinemia of the Nagase analbuminemic rat (NAR) is characterized by elevated concentrations of VLDL and LDL attributed to increased rates of liver lipoprotein synthesis. Increased lysophosphatidylcholine (LPC) in NAR HDL has been attributed to high plasma LCAT activity. We show here that, as compared with Spr...

journal_title：Lipids

authors： Catanozi S,Rocha JC,Passarelli M,Mesquita CH,Suguiama VY,Guzzo ML,dos Santos Filho A,Quintão EC,Nakandakare ER

更新日期：2006-07-01 00:00:00

abstract：:Factors involved in reduced glutathione (GSH) and vitamin E-mediated inhibition of NADPH-dependent rat liver microsomal lipid peroxidation were examined. Lipid peroxidation was monitored over a time-course of 180 min by thiobarbituric acid reactive product formation. The addition of 5 mM GSH to the reaction system con...

journal_title：Lipids

authors： Graham KS,Reddy CC,Scholz RW

更新日期：1989-11-01 00:00:00

abstract：:This study compared (i) the relative effects of long-chain triglycerides (LCT) and medium-chain triglycerides (MCT), (ii) the influence of amount of MCT, and (iii) the impact of medium-chain fatty acid position, on plasma and lymphatic triglycerides and portal vein free fatty acids. The animals were fed approximately ...

journal_title：Lipids

authors： You YQ,Ling PR,Qu Z,Bistrian BR

更新日期：1998-03-01 00:00:00

abstract：:An improved headspace capillary gas chromatographic (GC) method was developed to measure the oxidative susceptibility of human red blood cell (RBC) membranes. This method analyzed volatile peroxidation products of both n-6 (hexanal and pentane) and n-3 (propanal) polyunsaturated fatty acids. Oxidative susceptibility t...

journal_title：Lipids

authors： Frankel EN,Tappel AL

更新日期：1991-06-01 00:00:00

abstract：:The farnesoid X receptor (FXR, NR1H4) has been recognized as an attractive therapeutic target because it is a nuclear hormone receptor that controls the expression level of cholesterol-7alpha-hydroxylase, which in turn regulates bile acid production and cholesterol excretion. To compare receptor activity between each ...

journal_title：Lipids

authors： Cho KH,Park JY,Han JI,Jeong TS

更新日期：2003-11-01 00:00:00

abstract：:The effect of lecithin on jejunal absorption of fatty acids and octadecenoylglycerol was studied in healthy volunteers with a jejunal perfusion system which excluded pancreatic and biliary secretions from the test segment. Lecithin significantly reduced the absorption of oleic acid (P less than 0.05) and octadecenoylg...

journal_title：Lipids

authors： Ammon HV,Thomas PJ,Phillipis SF

更新日期：1979-04-01 00:00:00

abstract：:The purpose of the present investigation was to test whether permanent skeletal muscle cells (rat L6 cells) could serve as an in vitro model for alpha-tocopherol (alphaTocH) biodiscrimination studies. L6 cells were incubated in the presence of high density lipoprotein (HDL), low density lipoprotein (LDL), and very low...

journal_title：Lipids

authors： Nakamura T,Reicher H,Sattler W

更新日期：1998-10-01 00:00:00

abstract：:Unsaturated free fatty acids (FFA) are able to prevent deleterious effects of saturated FFA in skeletal muscle cells although the mechanisms involved are still not completely understood. FFA act as endogenous ligands of peroxisome proliferator-activated receptors (PPAR), transcription factors regulating the expression...

journal_title：Lipids

authors： Tumova J,Malisova L,Andel M,Trnka J

更新日期：2015-10-01 00:00:00

abstract：:Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects consuming a low fat (20% of calories) diet consisting of fatty acids...

journal_title：Lipids

authors： Sampugna J,Light L,Enig MG,Jones DY,Judd JT,Lanza E

更新日期：1988-02-01 00:00:00

abstract：:Decreased triacylglycerol synthesis within hepatocytes due to decreased diacylglycerol acyltransferase (DGAT) activity has been suggested to be an important mechanism by which diets rich in fish oil lower plasma triacylglycerol levels. New findings suggest that eicosapentaenoic acid (EPA), and not docosahexaenoic acid...

journal_title：Lipids

authors： Madsen L,Rustan AC,Vaagenes H,Berge K,Dyrøy E,Berge RK

更新日期：1999-09-01 00:00:00

abstract：:Among many factors, elevated lipids and lipid peroxide levels in blood are major risk factors in the development of cardiovascular disease in diabetic patients. This study has examined whether oral supplementation of vitamin E, an antioxidant, has any effect on blood lipid peroxidation products (LP) and lipid profile ...

journal_title：Lipids

authors： Jain SK,McVie R,Jaramillo JJ,Palmer M,Smith T,Meachum ZD,Little RL

更新日期：1996-03-01 00:00:00

abstract：:Two groups of volunteers had blood drawn for serum analysis of fatty acids. The first group was comprised of patients admitted to the hospital with possible myocardial infarction (MI). Blood was drawn at admission and at 12, 24 and 48 hr. These patients were subsequently divided into three groups, those with MI, those...

journal_title：Lipids

authors： Crofts JW,Ogburn PL Jr,Johnson SB,Holman RT

更新日期：1988-06-01 00:00:00

abstract：:Recently, lipases have been purified from mammalian, bacterial, fungal and plant sources by different methodologies. Purified lipases subsequently have been characterized for molecular size, metal binding capabilities, glycoside and phosphorus contents, and substrate specificities. Primary structures of several lipase...

journal_title：Lipids

authors： Antonian E

更新日期：1988-12-01 00:00:00

abstract：:Oxidized LDL (oxLDL) may contribute to the accumulation of apoptotic cells in atherosclerotic plaques. Although it is well established in monophasic chemical systems that the highly unsaturated EPA and DHA will oxidize more readily than FA that contain fewer double bonds, our previous studies showed that enrichment of...

journal_title：Lipids

authors： Wu T,Geigerman C,Lee YS,Wander RC

更新日期：2002-08-01 00:00:00

abstract：:Diacylglycerol acyltransferase (DGAT) catalyzes the final step of triacylglycerol (TAG) synthesis, and is considered as a potential target to control hypertriglyceridemia or other metabolic disorders. In this study, we found that the extract of rose petals suppressed TAG synthesis in cultured cells, and that the extra...

journal_title：Lipids

authors： Kondo H,Hashizume K,Shibuya Y,Hase T,Murase T

更新日期：2011-08-01 00:00:00

abstract：:The biosynthesis of 3R-hydroxy-5Z, 8Z, 11Z,14Z-eicosatetraenoic acid (3R-HETE) from arachidonic acid (20:4n-6) by the hyphal-forming yeast, Dipodascopsis uninucleata, in cell-free enzyme extracts required CoASH, ATP, NAD+ and Mg2+; 3R-HETE was present as the CoA derivative in enzyme extracts and its biosynthesis was a...

journal_title：Lipids

authors： Fox SR,Hamberg M,Friend J,Ratledge C

更新日期：2000-11-01 00:00:00

abstract：:The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds-methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal-were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbon...

journal_title：Lipids

authors： Khan A,Husain SR,Ahmad F,Siddiqui MS,Pimlott W

更新日期：1987-08-01 00:00:00

abstract：:If an increased consumption of alpha-linolenic acid (ALA) is to be promoted in parallel with that of n-3 long-chain-rich food, it is necessary to consider to what extent dietary ALA can be absorbed, transported, stored, and converted into long-chain derivatives. We investigated these processes in male hamsters, over a...

journal_title：Lipids

authors： Morise A,Combe N,Boué C,Legrand P,Catheline D,Delplanque B,Fénart E,Weill P,Hermier D

更新日期：2004-04-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor alpha (PPARalpha) belongs to the nuclear receptor superfamily that regulates multiple target genes involved in lipid metabolism. Cholesterol ester transfer protein (CETP) is a secreted glycoprotein that modifies high-density lipoprotein (HDL) particles. In humans, plasma CETP...

journal_title：Lipids

authors： Beyer TP,Chen Y,Porter RK,Lu D,Schmidt RJ,Mantlo NB,Konrad RJ,Cao G

更新日期：2008-07-01 00:00:00

abstract：:Serum opacity factor (SOF) is a streptococcal protein that disrupts the structure of human high density lipoproteins (HDL) releasing lipid-free apo A-I while forming a large cholesteryl ester-rich particle and a small neo HDL. Given its low cholesterol and high phospholipid contents, we tested the hypotheses that neo ...

journal_title：Lipids

authors： Tchoua U,Rosales C,Tang D,Gillard BK,Vaughan A,Lin HY,Courtney HS,Pownall HJ

更新日期：2010-12-01 00:00:00

abstract：:This review explores the effects of dietary long chain polyunsaturated fatty acids (LCPUFA) on various aspects of early immune development and their potential role in the development or the prevention of immune disease. Modern diets have become increasingly rich in n-6 LCPUFA and relatively n-3 LCPUFA deficient. These...

journal_title：Lipids

authors： Prescott SL,Dunstan JA

更新日期：2007-09-01 00:00:00

abstract：:The effects of n-3 fatty acids on plasma lipids, lipoproteins and apoproteins have usually been studied in humans after feeding of purified fish oil. This study describes the effect of a natural diet, containing salmon as the source of n-3 fatty acids, on these parameters as compared to a diet very low in n-3 fatty ac...

journal_title：Lipids

authors： Lindgren FT,Adamson GL,Shore VG,Nelson GJ,Schmidt PC

更新日期：1991-02-01 00:00:00

abstract：:Rats were fed semipurified diets containing olive oil or partially hydrogenated corn oil at the 5 or 20% level for ca. 30 days. These fat diets contained the same amount of octadecenoate but differed in the geometry with respect to each fat level. Contents of t-18:1 were 26% and 41% of total fatty acids, respectively....

journal_title：Lipids

authors： Watanabe M,Cho YJ,Ide T,Sugano M

更新日期：1984-02-01 00:00:00