Molecular genetics of plant sterol backbone synthesis.

abstract：:Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

journal_title：Lipids

authors： Burger WC,Qureshi AA,Prentice N,Elson CE

更新日期：1982-12-01 00:00:00

abstract：:We examined the initial transport of a long-chain unsaturated fatty acid, linoleic acid, by brush border membrane vesicles isolated from rabbit small intestine. This preparation allowed us to examine the transport of linoleic acid across the brush border membrane without the effect of the unstirred water layer or cyto...

journal_title：Lipids

authors： Ling KY,Lee HY,Hollander D

更新日期：1989-01-01 00:00:00

abstract：:The effects of 2-hexadecynoic acid on the growth and lipid metabolism of cultured 7288 (HTC) cells have been evaluated. Growth was inhibited by the acetylenic acid: the LD50 was 35-85 microM as determined by two methods at low and high cell densities. Reduced growth did not result from damaged plasma membranes as dete...

journal_title：Lipids

authors： Upreti GC,Matocha M,Wood R

更新日期：1981-05-01 00:00:00

abstract：:Soy isoflavones may impede atherogenic processes associated with cardiovascular disease. Research suggests that the postprandial generation of TG-rich remnants contributes to the development of atherosclerosis. The purpose of the current study was to determine if 39 g soy (85 mg aglycone isoflavones, treatment) compar...

journal_title：Lipids

authors： Campbell CG,Brown BD,Dufner D,Thorland WG

更新日期：2006-03-01 00:00:00

abstract：:We have investigated the regulation of cholesterol synthesis in isolated human small intestine epithelial cells (enterocytes). It was established that the amount of cholesterol synthesized increased linearly with the incubation time and the number of cells in the incubation mixture; the synthesis was suppressed by 7-k...

journal_title：Lipids

authors： Sviridov DD,Safonova IG,Talalaev AG,Repin VS,Smirnov VN

更新日期：1986-12-01 00:00:00

abstract：:The effect of 4,4'-diethylamino-ethoxyhexestrol (DH) on acid esterase in rat liver was studied in vivo and in vitro. The acid esterase activity in the livers of rats treated with 0.125% DH for 1 week was found to decrease more than 60% as compared with that in untreated rats. The addition of DH to the incubation mediu...

journal_title：Lipids

authors： Kasama K,Yoshida K,Takeda S,Tsujimura R,Hasegawa S

更新日期：1976-10-01 00:00:00

abstract：:Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 hu...

journal_title：Lipids

authors： Yates AJ,Franklin TK,Scheithauer BW,Burger PC,Pearl DK

更新日期：1999-01-01 00:00:00

abstract：:A simple method for the determination of bile acids in adult human fecal samples using GC-MS is described. Bile acids are directly extracted from feces by ethanol (95%) containing 0.1 N NaOH. Extracts are purified by passage through a reversed-phase C18 silica cartridge and then analyzed by GC-MS. The present study ha...

journal_title：Lipids

authors： Perwaiz S,Mignault D,Tuchweber B,Yousef IM

更新日期：2002-11-01 00:00:00

abstract：:A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...

journal_title：Lipids

authors： Siebert BD,Kruk ZA,Davis J,Pitchford WS,Harper GS,Bottema CD

更新日期：2006-04-01 00:00:00

abstract：:High-performance liquid chromatography-electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) approaches have enabled high selectivity and sensitivity for the identification and quantification of glucosylceramide molecular species. Here we demonstrate that HPLC-ESI-MS/MS is an efficient method for character...

journal_title：Lipids

authors： Imai H,Hattori H,Watanabe M

更新日期：2012-12-01 00:00:00

abstract：:A one-carbon degradation of long-chain fatty acids, which was found to occur in the brains of rats in vivo, has been investigated in a brain microsomal fraction in vitro. Decarboxylation of the alpha-hydroxy acid, a possible intermediate product between the substrate and the next shorter acid, in the presence of brain...

journal_title：Lipids

authors： Macdonald RC,Mead JF

更新日期：1968-05-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:Dietary fatty acids have different effects on fat deposition in pigs. To clarify the underlying mechanisms of this difference, we compared the metabolism of palmitic (PAM, saturated), oleic (OLA, monounsaturated) and linoleic acid (LNA, polyunsaturated) in porcine adipocytes treated with 100 μM PAM, OLA or LNA. We obs...

journal_title：Lipids

authors： Yu C,Xi L,Chen J,Jiang Q,Yi H,Wang Y,Wang X

更新日期：2017-11-01 00:00:00

abstract：:Flaxseed oil is an alpha linolenic acid source important in the growth and body development stage; furthermore, this acid acts on adipose tissue and bone health. The aim of this study was to evaluate body composition, fatty acid composition, hormone profile, retroperitoneal adipocyte area and femur structure of pups a...

journal_title：Lipids

authors： Pereira AD,Ribeiro DC,de Santana FC,de Sousa Dos Santos A,Mancini-Filho J,do Nascimento-Saba CC,Velarde LG,da Costa CA,Boaventura GT

更新日期：2016-08-01 00:00:00

abstract：:Chemical composition of subcellular components of HeLa, KB, human heart and liver tissue-culture cell lines have been studied.The concentration of RNA, protein and phospholipid (mug/mug of DNA) of total subcellular particles was similar for all four cell lines studied. The greatest RNA concentration and lowest protein...

journal_title：Lipids

authors： Tsao SS,Cornatzer WE

更新日期：1967-01-01 00:00:00

abstract：:A pilot study was undertaken to determine if moderate changes in linoleate (18:2 omega 6) intake would modulate the prostaglandin E turnover concurrently with, or independently of, changes in the plasma prostaglandin (PG) precursor levels. Four adult male volunteers in good health were fed two controlled diets contain...

journal_title：Lipids

authors： Ferretti A,Judd JT,Marshall MW,Flanagan VP,Roman JM,Matusik EJ Jr

更新日期：1985-05-01 00:00:00

abstract：:Pulmonary surfactant, the major surface-active component of which in the adult is dipalmitoylglycerophosphocholine, can be obtained by lavaging lungs with physiological saline. We have previously shown that there is an increase in the amount of phosphatidylcholine in fetal rabbit lung lavage during the latter part of ...

journal_title：Lipids

authors： Rooney SA,Gobran LI

更新日期：1977-12-01 00:00:00

abstract：:Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

journal_title：Lipids

authors： Waters KM,Ntambi JM

更新日期：1996-03-01 00:00:00

abstract：:In previous studies, zinc-deficient rats force-fed a diet with coconut oil as the major dietary fat developed a fatty liver, whereas zinc-deficient rats force-fed a diet with linseed oil did not. The present study was conducted to elucidate the reason for this phenomenon. In a bifactorial experiment, rats were fed zin...

journal_title：Lipids

authors： Eder K,Kirchgessner M

更新日期：1995-01-01 00:00:00

abstract：:After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incor...

journal_title：Lipids

authors： el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

更新日期：1987-10-01 00:00:00

abstract：:Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the k...

journal_title：Lipids

authors： Muñoz PA,Correa-Llantén DN,Blamey JM

更新日期：2015-01-01 00:00:00

abstract：:Stearoyl-coenzyme A desaturase-1 (SCD1) is a rate-limiting enzyme that catalyzes the biosynthesis of monounsaturated fatty acids from saturated fatty acids. Recently, SCD1 down-regulation has been implicated in the prevention of obesity, and the improvement of insulin and leptin sensitivity. In this study, we examined...

journal_title：Lipids

authors： Beppu F,Hosokawa M,Yim MJ,Shinoda T,Miyashita K

更新日期：2013-05-01 00:00:00

abstract：:The effect of apo very low density lipoprotein (apo VLDL) and apoprotein C-II on the phospholipase A1 activity associated with lipoprotein lipase (E.C.3.1.1.3) was studied using purified bovine milk lipoprotein lipase. The enzyme degraded 14C phosphatidylcholine (PC) to 14C 2-acyl lysophosphatidylcholine at a rate of ...

journal_title：Lipids

authors： Stocks J,Galton DJ

更新日期：1980-03-01 00:00:00

abstract：:A new spectrophotometric assay for determining the activity of acylglycerol hydrolases (lipases, E.C. 3.1.1.3) was developed and optimized for yeast lipase (Candida cylindracea). Studies with porcine pancreatic lipase were also conducted and the influence of various detergents and divalent cations on the assay was eva...

journal_title：Lipids

authors： Rogel AM,Stone WL,Adebonojo FO

更新日期：1989-06-01 00:00:00

abstract：:The purpose of this study was to assess changes in the degree of fatty acid unsaturation in rat liver after partial hepatectomy. This is the first study in which liver fatty acid unsaturation has been analyzed over a long period of regeneration until day 28 after operation. The relationship between changes in unsatura...

journal_title：Lipids

authors： Kishino T,Tanno M,Yamada H,Saito S,Matsumoto S

更新日期：2000-04-01 00:00:00

abstract：:While there are many reports of studies that fed arachidonic acid (AA) to animals, there are very few reports of AA feeding to humans under controlled conditions. This 130-d study was conceived as a controlled, symmetrical crossover design with healthy, adult male volunteers. They lived in the metabolic research unit ...

journal_title：Lipids

authors： Nelson GJ,Kelley DS,Emken EA,Phinney SD,Kyle D,Ferretti A

更新日期：1997-04-01 00:00:00

abstract：:The synthesis of phosphoglycerides is reviewed. Emphasis is placed upon precursor and intermediate compounds, phosphatidic acid, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, monoacylphosphoglycerides, purification and proof of structure. Suggestions are made for large scale synthesis of phosph...

journal_title：Lipids

authors： Jensen RG,Gordon DT

更新日期：1972-09-01 00:00:00

abstract：:We have studied the effect of various diets on the phospholipid fatty acid composition and in vitro delta 5 desaturase activity of hepatic microsomes derived either from the normal or streptozotocin-induced diabetic rat. The diets studied were the standard rat chow diet and a basal fat-free diet supplemented either wi...

journal_title：Lipids

authors： Dang AQ,Kemp K,Faas FH,Carter WJ

更新日期：1989-10-01 00:00:00

abstract：:The cleavage products formed by autoxidation of lycopene were evaluated in order to elucidate possible oxidation products of lycopene in biological tissues. Lycopene solubilized at 50 microM in toluene, aqueous Tween 40, or liposomal suspension was oxidized by incubating at 37 degrees C for 72 h. Among a number of oxi...

journal_title：Lipids

authors： Kim SJ,Nara E,Kobayashi H,Terao J,Nagao A

更新日期：2001-02-01 00:00:00

abstract：:The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds-methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal-were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbon...

journal_title：Lipids

authors： Khan A,Husain SR,Ahmad F,Siddiqui MS,Pimlott W

更新日期：1987-08-01 00:00:00