Maternal Flaxseed Oil During Lactation Enhances Bone Development in Male Rat Pups.

Abstract:

:Flaxseed oil is an alpha linolenic acid source important in the growth and body development stage; furthermore, this acid acts on adipose tissue and bone health. The aim of this study was to evaluate body composition, fatty acid composition, hormone profile, retroperitoneal adipocyte area and femur structure of pups at weaning, whose mothers were fed a diet containing flaxseed oil during lactation. After birth, pups were randomly assigned: control (C, n = 12) and flaxseed oil (FO, n = 12), rats whose mothers were treated with diet containing soybean or flaxseed oil. At 21 days, the pups were weaned and body mass, length, body composition, biochemical parameter, leptin, osteoprotegerin, osteocalcin, fatty acids composition, intra-abdominal fat mass and femur structure were analyzed. FO showed (p < 0.05): higher body mass (+12 %) and length (+9 %); body fat mass (g, +45 %); bone mineral density (+8 %), bone mineral content (+55 %) and bone area (+35 %), osteocalcin (+173 %) and osteoprotegerin (+183 %). Arachidonic acid was lower (p < 0.0001), alpha-linolenic and eicosapentaenoic were higher (p < 0.0001). Intra-abdominal fat mass was higher (+25 %), however, the retroperitoneal adipocytes area was lower (-44 %). Femur mass (+10 %), distance between epiphyses (+4 %) and bone mineral density (+13 %) were higher. The study demonstrates that adequate flaxseed oil content during a lactation diet plays an important role in the development of pups.

journal_name

Lipids

journal_title

Lipids

authors

Pereira AD,Ribeiro DC,de Santana FC,de Sousa Dos Santos A,Mancini-Filho J,do Nascimento-Saba CC,Velarde LG,da Costa CA,Boaventura GT

doi

10.1007/s11745-016-4165-6

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

923-9

issue

8

eissn

0024-4201

issn

1558-9307

pii

10.1007/s11745-016-4165-6

journal_volume

51

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Increased hepatic delta 6-desaturase activity with growth hormone expression in the MG101 transgenic mouse.

    abstract::Growth hormone (GH) has many metabolic effects, but its mechanism(s) of action are not fully understood. We studied the short-term effects of endogenously produced GH on liver delta 6-desaturase activity and adipose and liver lipid fraction fatty acid composition in transgenic mice. MG101 transgenic mice ages 73-114 d...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02522612

    authors: Nakamura MT,Phinney SD,Tang AB,Oberbauer AM,German JB,Murray JD

    更新日期:1996-02-01 00:00:00

  • Maternally-supplied fish oil alters piglet immune cell fatty acid profile and eicosanoid production.

    abstract::This study was designed to examine the incorporation of omega-3 (n-3) fatty acids into the immune tissues of pigs nursing fish oil-fed sows and to determine the effect of maternal dietary n-3 consumption on in vitro immune cell eicosanoid production. On day 107 of gestation, 12 sows were randomly allotted to a diet co...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535986

    authors: Fritsche KL,Alexander DW,Cassity NA,Huang SC

    更新日期:1993-08-01 00:00:00

  • Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice.

    abstract::Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02637047

    authors: Waters KM,Ntambi JM

    更新日期:1996-03-01 00:00:00

  • The effect of short-term lipid infusion on liver function and biliary secretion in rats.

    abstract::This study was undertaken to determine the effect of various lipid emulsions on the hepato-biliary system in rats. Rats were randomly divided into six groups and infused continuously for 48 hr with either long-chain triglycerides (LCT), medium-chain triglycerides (MCT) or a mixture of MCT and LCT. One group infused wi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536144

    authors: Rubin M,Halpern Z,Livoff A,Wennberg A,Tietz A,Antebi E,Lichtenberg D

    更新日期:1992-05-01 00:00:00

  • Comparative study of lipogenic enzymes in several vertebrates.

    abstract::The liver lipogenic enzymes are compared among rats, chickens, frogs and fish. Although the apparent Km values of glucose-6-phosphate dehydrogenase for glucose-6-phosphate are not much different among all the species, those of malic enzyme for malate are much higher in chickens and fish than in rats and frogs. Glucose...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534511

    authors: Iritani N,Ikeda Y,Fukuda H,Katsurada A

    更新日期:1984-11-01 00:00:00

  • Elevated production of docosahexaenoic acid in females: potential molecular mechanisms.

    abstract::Observational evidence suggests that in populations consuming low levels of n-3 highly unsaturated fatty acids, women have higher blood levels of docosahexaenoic acid (DHA; 22:3n-6) as compared with men. Increased conversion of alpha-linolenic acid (ALA; 18:3n-3) to DHA by females has been confirmed in fatty acid stab...

    journal_title:Lipids

    pub_type: 杂志文章,评审

    doi:10.1007/s11745-010-3391-6

    authors: Kitson AP,Stroud CK,Stark KD

    更新日期:2010-03-01 00:00:00

  • Changes in lipid content, fatty acid composition and lipoprotein lipase activity in dry goat omental adipose tissue according to tissue site.

    abstract::Water and lipid contents, fatty acid distribution, and lipoprotein lipase activity were determined in 11 samples taken from the Omentum Majus of five dry Alpine goats. Samples were chosen to standardize sampling sites using geometric guide marks representative of different adipose tissue sites. Sample location explain...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536391

    authors: Bas P,Gallouin F,Morand-Fehr P

    更新日期:1992-06-01 00:00:00

  • Variations in the molecular species of lung phosphatidylglycerol.

    abstract::Approximately 20% of the phosphatidylglycerol of the lung tissue of several animals was found to have both fatty acids saturated. Pulmonary washings from the lung of the rabbit and guinea pig had more saturated phosphatidylglycerol than the washed lung tissue. Lung-saturated phosphatidylglycerol was relatively low in ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533529

    authors: Okano G,Akino T

    更新日期:1979-06-01 00:00:00

  • Effects of different levels of dietary trans-octadecenoate on steroid metabolism in rats.

    abstract::Rats were fed semipurified diets containing olive oil or partially hydrogenated corn oil at the 5 or 20% level for ca. 30 days. These fat diets contained the same amount of octadecenoate but differed in the geometry with respect to each fat level. Contents of t-18:1 were 26% and 41% of total fatty acids, respectively....

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534500

    authors: Watanabe M,Cho YJ,Ide T,Sugano M

    更新日期:1984-02-01 00:00:00

  • A method for the quantitative analysis of molecular species of alkylacylglycerol and diacylglycerol.

    abstract::We describe a method for the quantitative analysis of molecular species of diacylglycerol and alkylacylglycerol as their diradylglycerobenzoate derivatives. Synthetic internal standards were used to provide quantitative determinations of the low levels of diacylglycerol and alkylacylglycerol and their individual molec...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544045

    authors: Warne TR,Robinson M

    更新日期:1990-11-01 00:00:00

  • Effects of essential fatty acid deficiency on prostaglandin synthesis and fatty acid composition in rat renal medulla.

    abstract::Studies are reported on the capacity of isolated rat renal papilla (inner medulla) to synthesize and release prostaglandin (PG) E from endogenous and exogenous precursor(s) during development of an essential fatty acid (EFA) deficiency in the rat. Weanling (21-day-old) male Sprague-Dawley rats were fed a fat-free diet...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533845

    authors: Dunham EW,Balasingam M,Privett OS,Nickell EC

    更新日期:1978-12-01 00:00:00

  • Comparative intestinal and colonic absorption of [4-14C] cholesterol in the rat.

    abstract::[4(-14)C] Cholesterol was administered as an aqueous emulsion with triolein and dry non-fat milk either directly into the upper duodenum or into the ileocaecal junction of lymph duct cannulated rats. Lymph flow rates were similar in the two groups of animals. Whereas ca. 53% of the administered tracer dose of choleste...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533375

    authors: Roy T,Treadwell CR,Vahouny GV

    更新日期:1978-01-01 00:00:00

  • Effect of continuous enteral medium-chain fatty acid infusion on lipid metabolism in rats.

    abstract::This study compared (i) the relative effects of long-chain triglycerides (LCT) and medium-chain triglycerides (MCT), (ii) the influence of amount of MCT, and (iii) the impact of medium-chain fatty acid position, on plasma and lymphatic triglycerides and portal vein free fatty acids. The animals were fed approximately ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-998-0204-z

    authors: You YQ,Ling PR,Qu Z,Bistrian BR

    更新日期:1998-03-01 00:00:00

  • Effects of administration of hypolipidemic agent, 2,2'''- [ (1-methyl-4, 4-diphenylbutylidene) bis (p-phenyleneoxy)] bistriethylamine oxalate (SQ 10,591) upon cholesterol esterification by aorta, adrenal, and testes of cholesterol-fed rabbits].

    abstract::Administration of 2,2'''-([1-methyl-4, 4-diphenylbutylidene] bis(p-phenyl-eneoxy]) bistriethylamine oxalate (SQ 10,591) at 20 mg/Kg daily for 5 days to cholesterol-fed rabbits resulted in no change in aortic microsomal cholesterol esterification with a palmitoyl coenzyme A substrate or of aortic mitochondrial choleste...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532164

    authors: Morin RJ

    更新日期:1975-02-01 00:00:00

  • Sesame seed and its lignans produce marked enhancement of vitamin E activity in rats fed a low alpha-tocopherol diet.

    abstract::Three series of experiments demonstrated that sesame seed and its lignans cause significant elevation of alpha-tocopherol content in rats. In Experiment 1, 20% sesame seed (with a negligible amount of alpha-tocopherol) supplementing 10 (low), 50 (normal), or 250 (high) mg/kg alpha-tocopherol diets (protein and fat con...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536287

    authors: Yamashita K,Iizuka Y,Imai T,Namiki M

    更新日期:1995-11-01 00:00:00

  • High-Fat Diet from Weaning until Early Adulthood Impairs T Cell Development in the Thymus.

    abstract::The growing prevalence of childhood obesity has become a serious health problem over the past few decades. Although the immune system is greatly affected by childhood obesity, whether obesity influences the T cell development in the thymus is poorly understood. In this study, we used a high-fat diet (HFD)-induced obes...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12193

    authors: Li H,Wetchapinant C,Zhang L,Wu K

    更新日期:2020-01-01 00:00:00

  • Dietary Fatty Acid Metabolism is Affected More by Lipid Level than Source in Senegalese Sole Juveniles: Interactions for Optimal Dietary Formulation.

    abstract::This study analyses the effects of dietary lipid level and source on lipid absorption and metabolism in Senegalese sole (Solea senegalensis). Juvenile fish were fed 4 experimental diets containing either 100 % fish oil (FO) or 25 % FO and 75 % vegetable oil (VO; rapeseed, linseed and soybean oils) at two lipid levels ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-4089-6

    authors: Bonacic K,Estévez A,Bellot O,Conde-Sieira M,Gisbert E,Morais S

    更新日期:2016-01-01 00:00:00

  • In vitro conversion of saturated to monounsaturated fatty acid by Ehrlich ascites cells.

    abstract::In this paper, evidence is presented on the capacity of Ehrlich ascites cells to synthesize in vitro monounsaturated fatty acids from radioactive palmitate. Localization of the double bond was determined by ozonolysis and subsequent reduction of the ozonides to aldesters followed by gas liquid chromatography. These re...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534994

    authors: Mercuri O,De Tomás ME,de Antueno RJ

    更新日期:1981-12-01 00:00:00

  • High levels of pancreatic nonspecific lipase in rattlesnake and leopard shark.

    abstract::Hydrolysis of synthetic triglycerides by rattlesnake and leopard shark pancreatic enzymes revealed striking differences in specificity, depending on the presence or absence of sodium taurocholate. Without added sodium taurocholate the classical specificity of pancreatic lipase was expressed. Rattlesnake enzymes, in th...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532361

    authors: Patton JS

    更新日期:1975-09-01 00:00:00

  • (S)-1,2-diacyl-3-acetins: Optically active triglycerides fromEuonymus verrucosus seed oil.

    abstract::The seed oil ofEuonymus verrucosus Scop., family Celastraceae, contains more than 90% 1,2-diacyl-3-acetins (monoacetotriglycerides). The constituent triglyceride acids, other than acetic, are the usual long-chain fatty acids.Thin-layer chromatography (TLC), infrared (IR) and hydrolysis with pancreatic lipase indicate ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533174

    authors: Kleiman R,Miller RW,Earle FR,Wolff IA

    更新日期:1967-11-01 00:00:00

  • Rapid three-step purification of a hepatic neutral cholesteryl ester hydrolase which is not the pancreatic enzyme.

    abstract::A rat liver cytosolic cholesteryl ester hydrolase (CEH) was purified 12,600-fold by ammonium sulfate precipitation, cation exchange chromatography and gel permeation high-performance liquid chromatography, with an overall yield of 20%. Its properties are compared to those of pancreatic CEH, with which it has sometimes...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536160

    authors: Ghosh S,Grogan WM

    更新日期:1991-10-01 00:00:00

  • Dose-response impact of various tocotrienols on serum lipid parameters in 5-week-old female chickens.

    abstract::The cholesterol-suppressive action of the tocotrienol-rich-fraction (TRF) of palm oil may be due to the effect of its constituent tocotrienols on beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase activity. The tocotrienols, modulate HMG-CoA reductase activity via a post-transcriptional mechanism. As a co...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-006-5119-1

    authors: Yu SG,Thomas AM,Gapor A,Tan B,Qureshi N,Qureshi AA

    更新日期:2006-05-01 00:00:00

  • Mechanism of anesthesia: the potency of four derivatives of octane corresponds to their hydrogen bonding capacity.

    abstract::The anesthetic potency of four derivatives of n-octane was measured by tadpole righting reflex and expressed as effective millimolar concentration of drug in membrane, EDM50. Potency diminished (ED50 increased) in this order: 1-octanol, EDM50 = 5.5; 1-(2-methoxyethoxy)octane, EDM50 = 28; 1-methoxyoctane, EDM50 = 61; a...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534936

    authors: Brockerhoff H,Brockerhoff S,Box LL

    更新日期:1986-06-01 00:00:00

  • Lipid composition and peroxide levels of mucosal cells in the rat large intestine in relation to dietary fat.

    abstract::To examine whether dietary fat alters membrane lipid composition and peroxidation of polyunsaturated fatty acids in "non-proliferative" and "proliferative" cells in the large intestine, Sprague-Dawley rats were fed diets providing a polyunsaturated-to-saturated fatty acid ratio of 1.2 or 0.3 at a high or low level of ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536069

    authors: Turini ME,Thomson AB,Clandinin MT

    更新日期:1991-06-01 00:00:00

  • Effects of different fractions of the barley kernel on the hepatic lipid metabolism of chickens.

    abstract::Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534592

    authors: Burger WC,Qureshi AA,Prentice N,Elson CE

    更新日期:1982-12-01 00:00:00

  • Differences in delta9 desaturase activity between Jersey- and Limousin-sired cattle.

    abstract::An experiment examined delta9 desaturase activity and FA composition in subcutaneous adipose tissue in two differing breeds of cattle. Jersey-sired cattle had significantly higher rates of desaturase activity than Limousin-sired cattle (1.55 vs. 0.75 nmol/mg protein/min). This difference was also demonstrated by a low...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1339-7

    authors: Siebert BD,Pitchford WS,Kruk ZA,Kuchel H,Deland MP,Bottema CD

    更新日期:2003-05-01 00:00:00

  • The simultaneous separation and quantitation of human milk lipids.

    abstract::A protocol using a dry column method was modified for the extraction of total lipids and the simultaneous separation and quantitation of neutral and polar lipids in human milk. The triacylglycerol, cholesterol, phospholipid and vitamin E contents of the lipid extracts were determined and compared with lipids extracted...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535216

    authors: Collins SE,Jackson MB,Lammi-Keefe CJ,Jensen RG

    更新日期:1989-08-01 00:00:00

  • Preferential redistribution of lipoprotein-unassociated apoA-IV to an HDL subpopulation with a high degree of LCAT modification.

    abstract::The relationship between LCAT mediated HDL modification and the redistribution of lipoprotein-unassociated apoA-IV to HDL was investigated in vitro. Immunoaffinity-isolated rat lipoprotein-unassociated apoA-IV was added to apoB-, apoE-, apoA-IV depleted, [3H]cholesterol labelled rat plasma and incubated at 37 degrees ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544075

    authors: Lefevre M,Goudey-Lefevre JC,Roheim PS

    更新日期:1989-12-01 00:00:00

  • Changes in host animal plasma lipids during hepatoma growth.

    abstract::The concentrations of the major neutral lipid and phospholipid classes in the plasma of rats bearing hepatoma 7288CTC were determined at various times after transplantation. The fatty acid composition of each lipid class was also analyzed quantitatively as tumor growth progressed. Generally, most lipid classes exhibit...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534066

    authors: Matocha M,Wood R

    更新日期:1980-06-01 00:00:00

  • Triolein and trilinolein ameliorate oxidized low-density lipoprotein-induced oxidative stress in endothelial cells.

    abstract::Uptake of oxidized low-density lipoprotein by endothelial cells is a critical step for the initiation of atherosclerosis. Triacylglycerol uptake in these cells is understood to be a part of the process. The present investigation, comparison among the effects of simple acylglycerol, including tristearin, triolein, and ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-014-3889-4

    authors: Luo T,Deng ZY,Li XP,Rao H,Fan YW

    更新日期:2014-05-01 00:00:00