High levels of pancreatic nonspecific lipase in rattlesnake and leopard shark.

Abstract:

:Hydrolysis of synthetic triglycerides by rattlesnake and leopard shark pancreatic enzymes revealed striking differences in specificity, depending on the presence or absence of sodium taurocholate. Without added sodium taurocholate the classical specificity of pancreatic lipase was expressed. Rattlesnake enzymes, in the presence of sodium taurocholate, attacked the unsaturated oleic acid in the 2-position of racemic glycerol-1-palmitate-2-oleate-3-stearate nearly twice as fast as either outside saturated fatty acid. In this instance, over 90% of the monoglyceride which accumulated were 1-monoglyceride. These results are attributed to very high levels of bile salt activated nonspecific lipase. Eight vertebrate species were compared. With the exception of the rattlesnake and leopard shark, the other species (3 elasmobranchs and 3 mammals) all exhibited low levels of nonspecific lipase, e.g. less than 5% hydrolysis of the 2-position of racemic glycerol-1-palmitate-2-oleate-3-stearate in the presence of sodium taurocholate.

journal_name

Lipids

journal_title

Lipids

authors

Patton JS

doi

10.1007/BF02532361

subject

Has Abstract

pub_date

1975-09-01 00:00:00

pages

562-4

issue

9

eissn

0024-4201

issn

1558-9307

journal_volume

10

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Down-regulation of hepatic stearoyl-CoA desaturase-1 expression by fucoxanthin via leptin signaling in diabetic/obese KK-A(y) mice.

    abstract::Stearoyl-coenzyme A desaturase-1 (SCD1) is a rate-limiting enzyme that catalyzes the biosynthesis of monounsaturated fatty acids from saturated fatty acids. Recently, SCD1 down-regulation has been implicated in the prevention of obesity, and the improvement of insulin and leptin sensitivity. In this study, we examined...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-013-3784-4

    authors: Beppu F,Hosokawa M,Yim MJ,Shinoda T,Miyashita K

    更新日期:2013-05-01 00:00:00

  • Dietary monounsaturated fatty acids are protective against metabolic syndrome and cardiovascular disease risk factors.

    abstract::Over 50 years of research has sought to define the role dietary fat plays in cardiovascular disease (CVD) risk. Although optimal dietary fat quantity has been keenly pursued over past decades, attention has recently centered on the value of dietary fat quality. The purpose of the present review is to provide a critica...

    journal_title:Lipids

    pub_type: 杂志文章,评审

    doi:10.1007/s11745-010-3524-y

    authors: Gillingham LG,Harris-Janz S,Jones PJ

    更新日期:2011-03-01 00:00:00

  • Replacement of dietary fish oil with increasing levels of linseed oil: modification of flesh fatty acid compositions in Atlantic salmon (Salmo salar) using a fish oil finishing diet.

    abstract::Five groups of salmon, of initial mean weight 127 +/- 3 g, were fed increasing levels of dietary linseed oil (LO) in a regression design. The control diet contained capelin oil (FO) only, and the same oil was blended with LO to provide the experimental diets. After an initial period of 40 wk, all groups were switched ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-004-1223-5

    authors: Bell JG,Henderson RJ,Tocher DR,Sargent JR

    更新日期:2004-03-01 00:00:00

  • Effect of lactation on lipolysis in rat adipose tissue.

    abstract::The concentrations of nonesterified fatty acids and glycerol in rat parametrial adipose tissue increased at peak lactation. Adipose tissue from lactating rats showed higher rates of release of nonesterified fatty acids and glycerol when incubated in vitro than did tissue from nonlactating rats, but there was a substan...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532850

    authors: Smith RW,Walsh A

    更新日期:1976-05-01 00:00:00

  • Changes in the cholesterol and phospholipid content of mouse spleen after Raucscher leukemia virus infection.

    abstract::The effect of Rauscher Leukemia Virus (MuLV-R) infection on the lipid composition of mouse spleen from BALB/c mice was investigated. Drastic changes in the lipid composition of the spleen as a result of tumor growth induced by the virus could be demonstrated at 21 days after infection. The molar ratio of cholesterol t...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533406

    authors: Montfoort A,Boere WA,Griensven LJLDV

    更新日期:1976-11-01 00:00:00

  • The phospholipid fatty acids of the marine spongeXestospongia muta.

    abstract::The rare phospholipid fatty acids 3,7,11-trimethyldodecanoic (1), 5,9-hexadecadienoic (2) and 12-methyl-hexadecanoic (3) were identified in the marine spongeXestospongia muta. Branched fatty acids inX. muta accounted for 35% of the total fatty acid mixture. It was observed that the occurrence of the 5,9-hexadecadienoi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535668

    authors: Carballeira NM,Maldonado L

    更新日期:1988-07-01 00:00:00

  • Fatty Acid Profile of Pacific Oyster, Crassostrea gigas, Fed Different Ratios of Dietary Seaweed and Microalgae during Broodstock Conditioning.

    abstract::The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12177

    authors: Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

    更新日期:2019-09-01 00:00:00

  • Electron microscopy may reveal structure of docosahexaenoic acid-rich oil within Schizochytrium sp.

    abstract::Schizochytrium sp. is an algae-like microorganism utilized for commercial production of docosahexaenoic acid (DHA)-rich oil and dried microalgae for use as a source of DHA in foods, feeds, and nutritional supplements. Electron microscopic analysis of whole cells of Schizochytrium sp. employing sample preparation by hi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0655-2

    authors: Ashford A,Barclay WR,Weaver CA,Giddings TH,Zeller S

    更新日期:2000-12-01 00:00:00

  • Apparent lack of effect of obesity on the soluble phosphatidic acid phosphatase activity in human adipose tissue.

    abstract::In view of previous reports that the activity of the Mg(++)-dependent phosphatidic acid phosphatase in adipose tissues of rat and mouse is elevated in obesity, we attempted to assay this activity in biopsies of human omental adipose tissue obtained from normal-weight and morbidly obese subjects in connection with oper...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544078

    authors: Björkhem I,al-Shurbaji A,Backman L,Arner P

    更新日期:1989-12-01 00:00:00

  • Lipolysis of corn, peanut and randomized peanut oils.

    abstract::Corn oil, peanut oil and randomized peanut oil exhibit different atherogenic potentials; peanut oil being more atherogenic than the other oils. This study was conducted to ascertain if the atherogenicity of these oils was related to their rates of lipolysis. Using both pancreatic lipase and milk lipoprotein lipase (LP...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534645

    authors: Kim HK,Kritchevsky D

    更新日期:1983-11-01 00:00:00

  • A highly active soluble diacylglycerol synthesizing system from developing rapeseed, Brassica napus L.

    abstract::The subcellular distribution of the enzymes of triacylglycerol biosynthesis has been studied in developing oilseed rape. All in vitro enzymatic activities from oleoyl-CoA to triacylglycerol were sufficient to account for the known rate of oleate deposition in triacylglycerol in vivo. The enzymatic activities from oleo...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535452

    authors: Murphy DJ

    更新日期:1988-03-01 00:00:00

  • The effect of an energy restricted low glycemic index diet on blood lipids, apolipoproteins and lipoprotein (a) among adolescent girls with excess weight: a randomized clinical trial.

    abstract::Some studies focused on the effect of the dietary glycemic index on lipoproteins and apolipoproteins in adults; however, little evidence exists among adolescents regarding the effect of a low glycemic index (LGI) diet on apolipoproteins and lipoprotein (a) (Lpa). This study was conducted to evaluate the effect of an L...

    journal_title:Lipids

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s11745-013-3834-y

    authors: Rouhani MH,Kelishadi R,Hashemipour M,Esmaillzadeh A,Azadbakht L

    更新日期:2013-12-01 00:00:00

  • Quantitation of 1,2-diacylglycerol in rat heart by iatroscan TLC/FID.

    abstract::1,2-Diacylglycerol, which has been recognized as one of the intracellular second messengers, was measured quantitatively in the lipid extract from rat hearts using the thin layer chromatography and flame ionization detection (TLC/FID) method. Cholesterol acetate was added to the tissue as an internal standard, and the...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535467

    authors: Okumura K,Hashimoto H,Ito T,Ogawa K,Satake T

    更新日期:1988-03-01 00:00:00

  • Changes in liver fatty acid unsaturation after partial hepatectomy in the rat.

    abstract::The purpose of this study was to assess changes in the degree of fatty acid unsaturation in rat liver after partial hepatectomy. This is the first study in which liver fatty acid unsaturation has been analyzed over a long period of regeneration until day 28 after operation. The relationship between changes in unsatura...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-543-9

    authors: Kishino T,Tanno M,Yamada H,Saito S,Matsumoto S

    更新日期:2000-04-01 00:00:00

  • Palmitic acid and oleic acid differentially regulate choline transporter-like 1 levels and glycerolipid metabolism in skeletal muscle cells.

    abstract::Choline is an essential nutrient required for the biosynthesis of membrane lipid phosphatidylcholine (PtdCho). Here we elucidate the mechanism of how palmitic acid (PAM) and oleic acid (OLA) regulate choline transporter-like protein 1 (CTL1/SLC44A1) function. We evaluated the mechanism of extracellular and intracellul...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-014-3925-4

    authors: Schenkel LC,Bakovic M

    更新日期:2014-08-01 00:00:00

  • Cheek cell fatty acids as indicators of dietary lipids in humans.

    abstract::Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects consuming a low fat (20% of calories) diet consisting of fatty acids...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535293

    authors: Sampugna J,Light L,Enig MG,Jones DY,Judd JT,Lanza E

    更新日期:1988-02-01 00:00:00

  • Hepatic bile acid elution by albumin and bile acid content in isolated rat hepatocytes.

    abstract::Bile acid contents were determined for isolated rat hepatocytes. During the course of isolating the hepatocytes, perfusion of rat liver with buffer containing 2% albumin eluted a significant amount of bile acids. The elution was proportional to the volume of the buffer and attributable to albumin in the buffer. The is...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535094

    authors: Hashimoto S,Uchida K,Hirata M

    更新日期:1982-03-01 00:00:00

  • Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patients with disorders of peroxisomal biogenesis.

    abstract::A patient with classic Zellweger syndrome was treated with docosahexaenoic acid ethyl ester (DHA-EE) for three months. Five other patients with Zellweger variants (four of them less than one-year-old and a five-year-old) were treated with DHA-EE until normalization of the DHA levels in erythrocytes. When arachidonic a...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02637067

    authors: Martinez M

    更新日期:1996-03-01 00:00:00

  • Synthesis of phosphatidylcholine and phosphatidylethanolamine at different ages in the rat brain in vitro.

    abstract::The de novo synthesis of choline and ethanolamine phosphoglycerides in brain microsomes from 18 month-old male rats was investigated in vitro by using labeled cytidine-5'-diphosphate choline and cytidine-5'-diphosphate ethanolamine as lipid precursors. The rate of synthesis of the two phospholipid classes was found to...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533507

    authors: Brunetti M,Gaiti A,Porcellati G

    更新日期:1979-11-01 00:00:00

  • Novel Non-methylene-Interrupted Dienoic and Trienoic Fatty Acids with a Terminal Double Bond in Ovaries of the Limpet Cellana toreuma.

    abstract::In this study, to obtain further information on the structural diversity of non-methylene-interrupted (NMI) fatty acids (FA) in the gonads of the limpet Cellana toreuma, previously unreported minor NMI FA, fractionated by argentation thin-layer chromatography (TLC), in the ovaries were characterized by gas chromatogra...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12225

    authors: Kawashima H

    更新日期:2020-05-01 00:00:00

  • Triglyceride sub-classes of various dog adipose tissue sites.

    abstract::Lipids were extracted from four dog adipose tissue sites, perirenal, pericardial, inguinal subcutaneous, and mesenteric. The triglycerides were purified by thin-layer chromatography and the sub-classes separated by silver nitrate-silica gel plates. Gas chromatography was used to delineate the fatty acid composition of...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02530899

    authors: Gold M

    更新日期:1968-11-01 00:00:00

  • Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain.

    abstract::The developmental changes in the fatty acid composition of ethanolamine phosphoglycerides (EPG) and choline phosphoglycerides (CPG) were studied in the liver and brain of 18 newborn infants with gestational ages ranging from 20 to 44 wk. A small group of five newborns receiving total parenteral nutrition (TPN) with hi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537290

    authors: Martínez M,Ballabriga A

    更新日期:1987-03-01 00:00:00

  • Use of a fluorescent radiolabeled triacylglycerol as a substrate for lipoprotein lipase and hepatic triglyceride lipase.

    abstract::A fluorescent radiolabeled triacylglycerol has been synthesized by using a fluorescent fatty acid (pyrene decanoic acid) and a radiolabeled oleic acid. This analog of the natural substrate, 1(3)pyrene decanoic-2,3 (1,2)-dioleoyl-sn-glycerol, has been tested as substrate for determining lipoprotein lipase and hepatic t...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535605

    authors: Dousset N,Negre A,Salvayre R,Rogalle P,Dang QQ,Douste-Blazy L

    更新日期:1988-06-01 00:00:00

  • High intake, but not low intake, of CLA impairs weight gain in growing mice.

    abstract::CLA has a range of biological properties, including effects on lipid metabolism and body composition in experimental animals. The prevalent isomer of CLA found in the human diet is 9c,11 t-CLA, and it is predominantly found in products containing fat from ruminant animals. This study investigated the effect of dietary...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-002-0950-y

    authors: Hayman A,MacGibbon A,Pack RJ,Rutherfurd K,Green JH

    更新日期:2002-07-01 00:00:00

  • Evidence that palmitic acid is absorbed as sn-2 monoacylglycerol from human milk by breast-fed infants.

    abstract::Milk fatty acids consist of about 20-25% palmitic acid (16:0), with about 70% of 16:0 esterified to the sn-2 position of the milk triacylglycerols. Hydrolysis of dietary triacylglycerols by endogeneous lipases produces sn-2 monoacylglycerols and free fatty acids, which are absorbed, reesterified, and then secreted int...

    journal_title:Lipids

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02536625

    authors: Innis SM,Dyer R,Nelson CM

    更新日期:1994-08-01 00:00:00

  • Formation of cleavage products by autoxidation of lycopene.

    abstract::The cleavage products formed by autoxidation of lycopene were evaluated in order to elucidate possible oxidation products of lycopene in biological tissues. Lycopene solubilized at 50 microM in toluene, aqueous Tween 40, or liposomal suspension was oxidized by incubating at 37 degrees C for 72 h. Among a number of oxi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-001-0706-8

    authors: Kim SJ,Nara E,Kobayashi H,Terao J,Nagao A

    更新日期:2001-02-01 00:00:00

  • Tritium and(14)C counting in tissue samples by using liquid scintillation method.

    abstract::The combustion method has been modified to increase the recovery of tritiated water after combustion of a tritium-labeled tissue sample. This was accomplished by cooling the bottom of the combustion flask in a dry ice-acetone bath while irradiating the top with an infrared lamp. The procedure resulted in at least 92% ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02531191

    authors: Parekh CK,Eigen E

    更新日期:1968-05-01 00:00:00

  • The effect of a short term saturated fat diet on the apoprotein composition and radioiodination properties of rat very low density lipoproteins.

    abstract::The effect of a saturated fat diet on the apoprotein composition and radioiodination properties of plasma very low density lipoprotein (VLDL) was studied in rats. After feeding the diet for 10 days, the proportion of 125I attached to VLDL lipid decreased from 50% (control animals) to 8%, the remainder (92%) being boun...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533349

    authors: Poulis P,Fidge NH

    更新日期:1977-03-01 00:00:00

  • Effect of dietary linoleic acid content on the distribution of triacylglycerol molecular species in rat adipose tissue.

    abstract::The present study examined the effect of varying dietary linoleate intake (0.01, 0.24, 2.4, 24, 80 or 160 g/kg diet) for 24 weeks on the distribution of triacylglycerol (TG) molecular species in rat epididymal adipose tissue. Adipose TG fractions were purified by thin-layer chromatography and separated into different ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536030

    authors: Huang YS,Lin X,Smith RS,Redden PR,Jenkins DK,Horrobin DF

    更新日期:1992-09-01 00:00:00

  • A sardine oil-rich diet increases iron absorption but does not compensate the hypoferremia associated with inflammation.

    abstract::Inflammatory disorders are associated with a decrease in iron absorption because of the blockade of iron in storage organs. Fish oils, rich in n-3 PUFA, are used to prevent and treat inflammatory disorders and increase iron absorption in noninflamed rats. Here we examine whether n-3 PUFA prevent inflammation-related h...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1131-8

    authors: Rodríguez MC,Sáiz MP,Mitjavila MT

    更新日期:2003-08-01 00:00:00