The Hordaland Homocysteine Studies.

Abstract:

:The Hordaland Homocysteine Study is a population-based screening of total plasma homocysteine (tHcy) in approximately 18,000 men and women aged 40-67 yr that took place in 1992-1993 in the county of Hordaland in Western Norway. In this cohort, tHcy was associated with several physiologic and life-style factors, including age and gender, blood pressure, serum cholesterol, smoking, alcohol and coffee consumption, physical activity, diet, and vitamin status. All associations with established cardiovascular risk factors were in the direction expected to confer increased risk. In a subset of 5,883 women aged 40-42 yr, tHcy was associated with previous pregnancy outcomes, including preeclampsia, placental abruption, and neural tube defects. This article reviews the published results from the Hordaland Homocysteine Study in the light of relevant literature. The Hordaland Homocysteine cohort will be used for future investigations of the stability of tHcy and vitamin status over time, and to investigate associations with mortality and morbidity including cancer incidence.

journal_name

Lipids

journal_title

Lipids

authors

Ueland PM,Nygård O,Vollset SE,Refsum H

doi

10.1007/s11745-001-0679-7

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

S33-9

eissn

0024-4201

issn

1558-9307

journal_volume

36 Suppl

pub_type

杂志文章

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