Substrate preferences of a lysophosphatidylcholine acyltransferase highlight its role in phospholipid remodeling.

abstract：:The suppression of plasma very low density lipoprotein (VLDL) triglyceride levels by dietary fish oils rich in polyunsaturated n-3 fatty acids has been attributed to decreased hepatic VLDL secretion. To investigate the effect of n-3 fatty acids on lipid metabolism and VLDL secretion in a tissue culture system, we incu...

journal_title：Lipids

authors： Benner KG,Sasaki A,Gowen DR,Weaver A,Connor WE

更新日期：1990-09-01 00:00:00

abstract：:The objective of the present studies was to examine the effect of dietary fat on the lipid composition of rat colonocytes and their utilization of short-chain fatty acids (SCFA). Rats were fed 14% beef fat, fish oil or safflower oil plus 2% corn oil in a semi-synthetic base diet for 4 wk. Colonocytes were isolated and...

journal_title：Lipids

authors： Awad AB,Ferger SL,Fink CS

更新日期：1990-06-01 00:00:00

abstract：:Soy isoflavones may impede atherogenic processes associated with cardiovascular disease. Research suggests that the postprandial generation of TG-rich remnants contributes to the development of atherosclerosis. The purpose of the current study was to determine if 39 g soy (85 mg aglycone isoflavones, treatment) compar...

journal_title：Lipids

authors： Campbell CG,Brown BD,Dufner D,Thorland WG

更新日期：2006-03-01 00:00:00

abstract：:In guinea pigs, total plasma cholesterol concentrations increased above the control values after single intravenous injections and after 3 days of continuous subcutaneous administration of neurotensin (NT). A high dose of NT (125 pmol/100 g body weight) induced tachycardia and severe respiratory distress; the lowest d...

journal_title：Lipids

authors： Peric-Golia L,Gardner CF,Wilson DE,Peric-Golia M

更新日期：1984-10-01 00:00:00

abstract：:Isolated rat hepatocytes were preincubated with egg lecithin liposomes containing [3H]dolichol and [3H]dolichyl ester, and the intracellular levels and distributions of these lipids were subsequently determined after incubation in a liposome-free medium. [3H]Dolichol was recovered initially mainly in microsomes, and n...

journal_title：Lipids

authors： Tollbom O,Chojnacki T,Dallner G

更新日期：1992-04-01 00:00:00

abstract：:The aim of the present study was to develop a cell culture system for studying the proliferation and differentiation of preadipocytes isolated from Atlantic salmon adipose tissue. The expression of proliferating cell nuclear antigen (PCNA) was used as a marker for cell proliferation. The cells started to proliferate w...

journal_title：Lipids

authors： Vegusdal A,Sundvold H,Gjøen T,Ruyter B

更新日期：2003-03-01 00:00:00

abstract：:The prevalence of colorectal cancer (CRC) continues to increase. Treatment of CRC remains a significant clinical challenge, and effective therapies for advanced CRC are desperately needed. Increasing attention and ongoing research efforts have focused on krill oil that may provide health benefits to the human body. He...

journal_title：Lipids

authors： Jing W,Bi Y,Wang G,Zeng S,Han L,Yang H,Wang N,Zhao Y

更新日期：2020-09-15 00:00:00

abstract：:The effect of 4,4'-diethylamino-ethoxyhexestrol (DH) on acid esterase in rat liver was studied in vivo and in vitro. The acid esterase activity in the livers of rats treated with 0.125% DH for 1 week was found to decrease more than 60% as compared with that in untreated rats. The addition of DH to the incubation mediu...

journal_title：Lipids

authors： Kasama K,Yoshida K,Takeda S,Tsujimura R,Hasegawa S

更新日期：1976-10-01 00:00:00

abstract：:The purpose of this study was to examine the effects of two purified isomers of CLA (c9,t11-CLA and t10,c12-CLA) on the weights and FA compositions of hepatic TG, phospholipids, cholesterol esters, and FFA. Eight-week-old female mice (n = 6/group) were fed either a control diet or diets supplemented with 0.5% c9,t11-C...

journal_title：Lipids

authors： Kelley DS,Bartolini GL,Warren JM,Simon VA,Mackey BE,Erickson KL

更新日期：2004-02-01 00:00:00

abstract：:Epoxidation of the double bond in methyl oleate, octadec-11E-en-9-ynoate, ricinoleate (12-hydroxy-octadec-9Z-enoate), iso-ricinoleate (9-hydroxy-octadec-12Z-enoate), and 12-oxo-octadec-9Z-enoate with potassium peroxomonosulfate (oxone, 2 KHSO5.KHSO4.K2SO4) in the presence of trifluoroacetone or methyl pyruvate gave th...

journal_title：Lipids

authors： Lie Ken Jie MS,Pasha MK

更新日期：1998-06-01 00:00:00

abstract：:Tris(N,N-dimethyl)amide of phosphorous acid activated by addition of iodine at an optimal molar ratio of 1.05:0.05 was used as a phosphorylating reagent to synthesize cholecalciferyl-3-O-(1-2-isopropylidene-rac-glycero-3-O-)-thiophos phate and cholecalciferyl-3-O-(1,2-dipalmitoyl-rac-glycero-3-O-)thiophosphat e of met...

journal_title：Lipids

authors： Stamatov SD,Gronowitz S

更新日期：1992-06-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:A mutant of Mortierella alpina, JT-180, which is defective in its delta12 desaturase activity but exhibits enhanced activities of delta5 and delta6 desaturases, produced a high proportion (up to 80%) of odd-chain FA when grown on 3% n-heptadecane. Following growth of the mutant on n-heptadecane, three unusual odd-chai...

journal_title：Lipids

authors： Zhang S,Sakuradani E,Shimizu S

更新日期：2006-06-01 00:00:00

abstract：:To see how the metabolism of specific phosphatidyl choline fractions might be affected when only a limited source of methyl groups was available, rats were fed for 7 days a low methionine, choline-deficient diet or one supplemented with either choline or methionine. Prior to killing, they were injected with -14C-methy...

journal_title：Lipids

authors： Lyman RL,Giotas C,Medwadowski B,Miljanich P

更新日期：1975-03-01 00:00:00

abstract：:The purpose of this study was to compare fish intake and plasma phospholipid concentrations of n-3 fatty acids, in particular of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among representative population samples of Québecers, James Bay Cree, and Inuit of Nunavik (Canada). The relationships between the...

journal_title：Lipids

authors： Dewailly E,Blanchet C,Gingras S,Lemieux S,Holub BJ

更新日期：2003-04-01 00:00:00

abstract：:A group of homologous, nonmethylene-interrupted dienoic fatty acids (NMID) recently reported in oysters has been found in several other shellfish species and also in other marine phyla. The distribution of most other "normal" fatty acids among several species of shellfish is basically similar but mantle lipids from tw...

journal_title：Lipids

authors： Paradis M,Ackman RG

更新日期：1977-02-01 00:00:00

abstract：:Changes in a number of morphological and biochemical parameters were observed in genetically obese Zucker rats and in lean controls between 3 and 58 weeks of age. By 3 weeks, the genetically obese rats had higher proportional (wt/100 g body wt) and absolute amounts of adipose tissue, hyperlipemia affecting all the lip...

journal_title：Lipids

authors： Bach A,Schirardin H,Bauer M,Schaeffer A,Weryha A

更新日期：1981-11-01 00:00:00

abstract：:Several experimental approaches were used to determine whether rat liver and testes express an acyl-CoA-dependent delta8 desaturase. When [1-14C]5,11,14-eicosatrienoic acid was injected via the tail vein, or directly into testes, it was incorporated into liver and testes phospholipids, but it was not metabolized to ot...

journal_title：Lipids

authors： Chen Q,Yin FQ,Sprecher H

更新日期：2000-08-01 00:00:00

abstract：:The rare phospholipid fatty acids 3,7,11-trimethyldodecanoic (1), 5,9-hexadecadienoic (2) and 12-methyl-hexadecanoic (3) were identified in the marine spongeXestospongia muta. Branched fatty acids inX. muta accounted for 35% of the total fatty acid mixture. It was observed that the occurrence of the 5,9-hexadecadienoi...

journal_title：Lipids

authors： Carballeira NM,Maldonado L

更新日期：1988-07-01 00:00:00

abstract：:Several of a series of linoleic acid amides have been reported to inhibit cholesterol-induced atherosclerosis in rabbits. The three amides which have been studied to the greatest extent are (in order of increasing activity) N-cyclohexyl linoleamide (AC23), N(alpha methylbenzyl) linoleamide (AC223), and N[aplha-phenyl-...

journal_title：Lipids

authors： Kritchevsky D,Tepper SA,Story JA

更新日期：1977-01-01 00:00:00

abstract：:Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

journal_title：Lipids

authors： Kim HY,Hamilton J

更新日期：2000-02-01 00:00:00

abstract：:The present studies tested the hypothesis that some effects of tumor necrosis factor-alpha (TNF-alpha) are mediated by activation of sphingomyelinases and the production of ceramides. Differentiated 3T3-L1 adipocytes were incubated with short-chain ceramide analogs, (C2- and C6-ceramides: N-acetyl- and N-hexanoyl-sphi...

journal_title：Lipids

authors： Brindley DN,Wang CN,Mei J,Xu J,Hanna AN

更新日期：1999-01-01 00:00:00

abstract：:The activity of the platelet-activating factor (PAF)-synthesizing enzyme, 1-O-alkyl-sn-glycero-3-phosphocholine (lysoPAF):acetyl-CoA acetyltransferase (EC 2.3.1.67) in alveolar macrophage lysate was found to be elevated after warming the cells to 37 degrees C. Such an increase in enzyme activity was detectable only wh...

journal_title：Lipids

authors： Sugiura T,Fukuda T,Cheng NN,Waku K

更新日期：1991-11-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. Stress promotes the onset of the NAFLD with a concomitant increment in the activity of the hepatic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). However, the interaction between the stress and a carbohydrate-enriched diet for t...

journal_title：Lipids

authors： Corona-Pérez A,Díaz-Muñoz M,Rodríguez IS,Cuevas E,Martínez-Gómez M,Castelán F,Rodríguez-Antolín J,Nicolás-Toledo L

更新日期：2015-11-01 00:00:00

abstract：:Cholesteryl esterase activities were determined in homogenates of rat heart (ventricles), isolated, calcium-tolerant, cardiac myocytes and aortic tissue and were compared with acid and neutral triglyceride lipase activities in these fractions. Using cholesteryl oleate/phosphatidylcholine/taurocholate emulsions and dig...

journal_title：Lipids

authors： Stam H,Broekhoven-Schokker S,Schoonderwoerd K,Hülsmann WC

更新日期：1987-02-01 00:00:00

abstract：:Peroxidation of intact human erythrocytes by t-butylhydroperoxide (tBHP)) was studied. By incubation of the erythrocytes with 1 mM tBHP, reduced glutathione (GSH) was exhausted within 1 min, and tocopherols (Toc) and phospholipids (PL) decreased to nearly their lowest levels (in this study) within 5 min. The rate of d...

journal_title：Lipids

authors： Mawatari S,Murakami K

更新日期：2001-01-01 00:00:00

abstract：:Lipoxygenase was isolated and partially purified from peanut seed by ammonium sulfate precipitation, gel filtration, and ion exchange column chromatography. Three isozymes of lipoxygenase were identified. Two had pH optima of 6.2, and the other an optimum of 8.3. Molecular weight of each isozyme was 7.3 x 10(4), as de...

journal_title：Lipids

authors： Sanders TH,Pattee HE,Singleton JA

更新日期：1975-11-01 00:00:00

abstract：:The molecular species in mixtures of phospholipid hydroperoxides are difficult to separate and identify by typical chromatographic and mass spectrometric techniques. As reported by Havrilla and coworkers, silver ion coordination ion-spray mass spectrometry (CIS-MS) has proven to be a powerful technique for the identif...

journal_title：Lipids

authors： Milne GL,Porter NA

更新日期：2001-11-01 00:00:00

abstract：:During ruminal biohydrogenation of α-linolenic acid, a non-conjugated non-methylene interrupted dienoic acid is formed containing a t10 double bond, namely t10,c15-18:2. The present study was designed to examine whether t10,c15-18:2 would exert similar anti-adipogenic effects compared to t10,c12-18:2 in 3T3-L1 adipocy...

journal_title：Lipids

authors： Vahmani P,Meadus WJ,Rolland DC,Duff P,Dugan ME

更新日期：2016-11-01 00:00:00

abstract：:Male Wistar rats were fed semipurifed diets containing 20% fat for 25 weeks. Ten different oils or oil blends were employed, including rapessed oils, simulated rapeseed-type oils, and modified rapeseed-type oils. Safflower, soybean, and hydrogenated coconut oils served as control oils. Histopathological examination of...

journal_title：Lipids

authors： McCutcheon JS,Umermura T,Bhatnager MK,Walker BL

更新日期：1976-07-01 00:00:00