The hepatocellular transport of sulfobromophthalein-glutathione by clofibrate treated, perfused rat liver.

abstract：:Gallstone formation and dissolution were studied in a prairie dog model of cholesterol (CH) cholelithiasis. Gallstones were induced in 49 prairie dogs by feeding 1.2% CH in a nutritionally adequate semisynthetic diet for 6 wk (period 1). At 6 wk, gallstones had developed in all animals examined. The diets were modifie...

journal_title：Lipids

authors： Cohen BI,Mosbach EH,McSherry CK,Rzigalinski B,Kuroki S

更新日期：1986-09-01 00:00:00

abstract：:1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor, PAF) is known to stimulate platelet aggregation and serotonin release in concentrations ranging from 10(-10)-10(-5) M. Since a variety of synthetic PAF analogues are potent antineoplastic agents in vitro and in vivo, it was the aim of th...

journal_title：Lipids

authors： Söling U,Eibl H,Nagel GA,Unger C

更新日期：1987-11-01 00:00:00

abstract：:The objective of this study was to examine whether whole body oxidation rates of dietary linoleic, alpha-linolenic and oleic acids differ when the acids are provided in identical quantities. Male rats were fed for 10 wk a 15% fat (w/w) diet containing equal amounts of linoleic, alpha-linolenic and oleic acids (22.7, 2...

journal_title：Lipids

authors： Jones PJ

更新日期：1994-07-01 00:00:00

abstract：:Although migrating birds use stored triacylglycerol as their primary fuel for flight, they must retain sufficient stores of omega 6 and omega 3 fatty acids to sustain reproduction after the spring migration. Hepatic monoacylglycerol:acyl-coenzyme A acyltransferase (EC 2.3.1.22) (MGAT) activity is associated with physi...

journal_title：Lipids

authors： Mostafa N,Bhat BG,Coleman RA

更新日期：1994-11-01 00:00:00

abstract：:Bdellovibrionales is a phylogenetically diverse group of predatory prokaryotes, which consists of the two families Bdellovibrionaceae and Bacteriovoracaceae. We describe LPS and lipid A of the type strain Bacteriovorax stolpii DSM 12778, representing the first characterized endotoxin of a Bacteriovoracaceae member. It...

journal_title：Lipids

authors： Beck S,Müller FD,Strauch E,Brecker L,Linscheid MW

更新日期：2010-02-01 00:00:00

abstract：:Apolipoprotein E (apo E) plays an essential role in lipoprotein metabolism, where it is involved in the clearance of chylomicrons and very low density lipoproteins. Apart from some rare variants, apo E exists in three common isoforms (E2, E3, and E4). The different isoforms have not only been associated with different...

journal_title：Lipids

authors： Wiebe C,Holzem G,Wielckens K,Klingler KR

更新日期：2000-01-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor alpha (PPARalpha) belongs to the nuclear receptor superfamily that regulates multiple target genes involved in lipid metabolism. Cholesterol ester transfer protein (CETP) is a secreted glycoprotein that modifies high-density lipoprotein (HDL) particles. In humans, plasma CETP...

journal_title：Lipids

authors： Beyer TP,Chen Y,Porter RK,Lu D,Schmidt RJ,Mantlo NB,Konrad RJ,Cao G

更新日期：2008-07-01 00:00:00

abstract：:In the present paper, problems in connection with assay of the activity of magnesium-dependent rat liver phosphatidate phosphohydrolase (PAP) are discussed. PAP activity is usually measured by following the production of diacylglycerol or inorganic phosphate from the substrate phosphatidate. These two methods may give...

journal_title：Lipids

authors： Stark M,Humble E

更新日期：1996-10-01 00:00:00

abstract：:In tests with purified menhaden oil at 37C and with squalene at 37C and 50C, unsubstituted tocol, 7,8-dimethyl tocol (gamma-tocol), and 8-methyl tocol (sigma-tocol) were superior antioxidants to 5,7-dimethyl tocol and 5,7,8-trimethyl tocol (alpha-tocol). In contrast to previous reports, there were no differences in th...

journal_title：Lipids

authors： Olcott HS,Van der Veen J

更新日期：1968-07-01 00:00:00

abstract：:Rats were fed diets with three different ratios of alpha-linolenate (18:3 n-3) and linoleate (18:2 n-6), and then crescentic-type anti-glomerular basement membrane (GBM) nephritis was induced. The urinary protein levels and the plasma urea nitrogen levels were significantly higher, and histological abnormalities of gl...

journal_title：Lipids

authors： Watanabe S,Suzuki E,Kojima R,Suzuki Y,Okuyama H

更新日期：1990-05-01 00:00:00

abstract：:Isolated rat hepatocytes were preincubated with egg lecithin liposomes containing [3H]dolichol and [3H]dolichyl ester, and the intracellular levels and distributions of these lipids were subsequently determined after incubation in a liposome-free medium. [3H]Dolichol was recovered initially mainly in microsomes, and n...

journal_title：Lipids

authors： Tollbom O,Chojnacki T,Dallner G

更新日期：1992-04-01 00:00:00

abstract：:Vegetable oils are an extremely important agricultural commodity. Their use has risen inexorably for the last 50 years and will undoubtedly be even more prevalent in the future. They have a role not only in foodstuffs but also as renewable chemicals. However, our understanding of their metabolism, and particularly its...

journal_title：Lipids

authors： Chen G,Woodfield HK,Pan X,Harwood JL,Weselake RJ

更新日期：2015-11-01 00:00:00

abstract：:The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...

journal_title：Lipids

authors： Reddy TS,Bazan NG

更新日期：1984-12-01 00:00:00

abstract：:The de novo synthesis of choline and ethanolamine phosphoglycerides in brain microsomes from 18 month-old male rats was investigated in vitro by using labeled cytidine-5'-diphosphate choline and cytidine-5'-diphosphate ethanolamine as lipid precursors. The rate of synthesis of the two phospholipid classes was found to...

journal_title：Lipids

authors： Brunetti M,Gaiti A,Porcellati G

更新日期：1979-11-01 00:00:00

abstract：:In experiments with 4 different types of cells, we evaluated the cholesterogenic activity by incorporation of 14C-acetic acid into cholesterol and digitonin-precipitable sterols. In every case, the cholesterogenesis appeared considerably faster when expressed as digitonid than when expressed as real cholesterol produc...

journal_title：Lipids

authors： Tabacik C,Aliau S,Crastes de Paulet A

更新日期：1983-09-01 00:00:00

abstract：:In the present study, changes in phospholipid compositions of liver microsomes, erythrocyte membranes, platelets, aorta, cardiac muscle and brain of rats fed olive oil were compared with those of rats fed sunflower oil. Four groups of rats starting at weaning were fed for four weeks a basal diet containing 5 or 25% ol...

journal_title：Lipids

authors： Navarro MD,Periago JL,Pita ML,Hortelano P

更新日期：1994-12-01 00:00:00

abstract：:The levels of arachidonic acid and linoleic acid found in the lipid fraction of human milk samples were compared. No correlation was found between the level of precursor linoleate and product arachidonate in 80 samples of colostrum (day 3-5) or 60 samples of mature breast milk. We attempted to test the hypothesis that...

journal_title：Lipids

authors： Gibson RA,Kneebone GM

更新日期：1984-06-01 00:00:00

abstract：:The farnesoid X receptor (FXR, NR1H4) has been recognized as an attractive therapeutic target because it is a nuclear hormone receptor that controls the expression level of cholesterol-7alpha-hydroxylase, which in turn regulates bile acid production and cholesterol excretion. To compare receptor activity between each ...

journal_title：Lipids

authors： Cho KH,Park JY,Han JI,Jeong TS

更新日期：2003-11-01 00:00:00

abstract：:After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incor...

journal_title：Lipids

authors： el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

更新日期：1987-10-01 00:00:00

abstract：:Levels of serum lipids and lipoproteins, and the fatty acid composition of plasma phospholipids, were measured in two genetically comparable, but widely separated, populations. The 1975 mortality rates for ischemic heart disease were significantly higher in one of these populations, the Manitoban residents of pure Ice...

journal_title：Lipids

authors： Skúladóttir GV,Gudmundsdóttir S,Olafsson GB,Sigurdsson SB,Sigfússon N,Axelsson J

更新日期：1995-07-01 00:00:00

abstract：:Plasma lipidomic studies using high performance liquid chromatography and mass spectroscopy offer detailed insights into metabolic processes. Taking the example of the most abundant plasma lipid class (phosphatidylcholines) we used the rich phenotypic and lipidomic data from the ongoing San Antonio Family Heart Study ...

journal_title：Lipids

authors： Kulkarni H,Meikle PJ,Mamtani M,Weir JM,Barlow CK,Jowett JB,Bellis C,Dyer TD,Johnson MP,Rainwater DL,Almasy L,Mahaney MC,Comuzzie AG,Blangero J,Curran JE

更新日期：2013-05-01 00:00:00

abstract：:Alteration of lipid constituents of cellular membranes has been proposed as a possible mechanism for cancer promotion by fumonisin B(1 )(FB(1)). To further investigate this hypothesis a dietary dosage which initiates and promotes liver cancer (250 mg FB(1)/kg) was fed to male Fischer rats for 21 days and the lipid com...

journal_title：Lipids

authors： Burger HM,Abel S,Snijman PW,Swanevelder S,Gelderblom WC

更新日期：2007-04-01 00:00:00

abstract：:The effect of dietary n-3 FA deficiency on bone tissue FA composition was evaluated in growing rats. Two mixtures combining hydrogenated coconut oil with safflower oil served as the n-3-deficient dietary treatments and provided two levels of linoleic acid (LA). The n-3 treatments were formulated with added alpha-linol...

journal_title：Lipids

authors： Li Y,Greiner RS,Salem N Jr,Watkins BA

更新日期：2003-06-01 00:00:00

abstract：:Several of a series of linoleic acid amides have been reported to inhibit cholesterol-induced atherosclerosis in rabbits. The three amides which have been studied to the greatest extent are (in order of increasing activity) N-cyclohexyl linoleamide (AC23), N(alpha methylbenzyl) linoleamide (AC223), and N[aplha-phenyl-...

journal_title：Lipids

authors： Kritchevsky D,Tepper SA,Story JA

更新日期：1977-01-01 00:00:00

abstract：:Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

journal_title：Lipids

authors： Burger WC,Qureshi AA,Prentice N,Elson CE

更新日期：1982-12-01 00:00:00

abstract：:Over 50 years of research has sought to define the role dietary fat plays in cardiovascular disease (CVD) risk. Although optimal dietary fat quantity has been keenly pursued over past decades, attention has recently centered on the value of dietary fat quality. The purpose of the present review is to provide a critica...

journal_title：Lipids

authors： Gillingham LG,Harris-Janz S,Jones PJ

更新日期：2011-03-01 00:00:00

abstract：:Trilinoleoylglycerol (LLL), trilinolenoylglycerol (LnLnLn) and four synthetic triacylglycerols were autoxidized and the volatile products were investigated to determine the effect of fatty acid glyceride position on the mechanism of hydroperoxide decomposition. Capillary gas chromatography provided a sensitive method ...

journal_title：Lipids

authors： Frankel EN,Selke E,Neff WE,Miyashita K

更新日期：1992-06-01 00:00:00

abstract：:Peanut oil was shown to be atherogenic in cholesterol-fed rats, rabbits, and monkeys. However, after randomization, a process in which the fatty acids in peanut oil are randomly rearranged, its atherogenicity was significantly reduced in cholesterol-fed rabbits and monkeys. The mechanism for this effect remains unknow...

journal_title：Lipids

authors： Satchithanandam S,Flynn TJ,Calvert RJ,Kritchevsky D

更新日期：1999-12-01 00:00:00

abstract：:Commercial fish oils and foods containing fish may contain trans and/or isomerized fatty acids (FA) produced during processing or as part of prepared foods. The current American Oil Chemists' Society (AOCS) official method for marine oils (method Ce 1i-07) is based on separation by use of poly(ethylene glycol) (PEG) c...

journal_title：Lipids

authors： Santercole V,Delmonte P,Kramer JK

更新日期：2012-03-01 00:00:00

abstract：:Strong perturbation of the ultraviolet spectrum of the tyrosines of porcine pancreatic colipase A is observed in the presence of Triton X-100 at concentration above the critical micellar concentration. Spectrophotometric titration of the phenolic groups of the protein shows that the apparent pKa value for two tyrosine...

journal_title：Lipids

authors： Canioni P,Julien R,Rathelot J,Sarda L

更新日期：1980-01-01 00:00:00