Abstract:
:The objective of this study was to examine whether whole body oxidation rates of dietary linoleic, alpha-linolenic and oleic acids differ when the acids are provided in identical quantities. Male rats were fed for 10 wk a 15% fat (w/w) diet containing equal amounts of linoleic, alpha-linolenic and oleic acids (22.7, 23.0 and 23.2% of total fatty acids, respectively). At week 10, after overnight fasting, rats were intragastrically administered 20 microCi of either [1-14C]-labelled linoleic, alpha-linolenic or oleic acid in a 200-microL bolus of oil containing equal quantities of each fatty acid. The appearance of 14CO2 in expired air was then monitored hourly for 12 h for each animal. A preliminary study had shown that growth and food consumption patterns in animals consuming the oil containing equal quantities of each of the fatty acids paralleled the patterns of animals that were self-selecting among separate diets, each of which contained one of the component oils. The appearance of 14C, expressed as percent dose administered, peaked at 2-3 h post-dose for 14C-labelled linoleic (5.28 +/- 0.37%/h), alpha-linolenic (6.92 +/- 0.51%/h) and oleic (5.98 +/- 0.44%/h) acids. Statistically these values were not significantly different. Cumulative 14CO2 excretion rates over 12 h were also similar for linoleic (27.2 +/- 0.9%), alpha-linolenic (26.8 +/- 1.2%) and oleic (25.9 +/- 1.2%) acids. The results suggest that the rat's capacity to oxidize 18-carbon unsaturated fatty acids is not affected by fatty acid unsaturation when these fatty acids are provided at equal dietary levels.
journal_name
Lipidsjournal_title
Lipidsauthors
Jones PJdoi
10.1007/BF02578246subject
Has Abstractpub_date
1994-07-01 00:00:00pages
491-5issue
7eissn
0024-4201issn
1558-9307journal_volume
29pub_type
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