Biosynthesis of molecular species of CDP-diglyceride from endogenously-labeled phosphatidate in rat liver microsomes.

abstract：:The acylation of lysophospholipids by rat liver acyltransferases was studied. A comparison between ester and ether lysophospholipids as substrates revealed large differences in substrate properties. For instance, oleic acid from oleoyl-CoA and arachidonic acid from arachidonoyl-CoA were not incorporated into 1-O-octad...

journal_title：Lipids

authors： Neumüller W,Fleer EA,Unger C,Eibl H

更新日期：1987-11-01 00:00:00

abstract：:The effect of 4,4'-diethylamino-ethoxyhexestrol (DH) on acid esterase in rat liver was studied in vivo and in vitro. The acid esterase activity in the livers of rats treated with 0.125% DH for 1 week was found to decrease more than 60% as compared with that in untreated rats. The addition of DH to the incubation mediu...

journal_title：Lipids

authors： Kasama K,Yoshida K,Takeda S,Tsujimura R,Hasegawa S

更新日期：1976-10-01 00:00:00

abstract：:Meal fatty acids have been shown to modulate the size and composition of triacylglycerol (TAG)-rich lipoproteins influencing the magnitude and duration of the postprandial plasma TAG response. As a result there is considerable interest in the origin of these meal fatty-acid induced differences in particle composition....

journal_title：Lipids

authors： Jackson KG,Bateman PA,Yaqoob P,Williams CM

更新日期：2009-12-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) is a collective term that describes different isomers of linoleic acid with conjugated double bonds. Although the main dietary isomer is 9cis,11trans-18:2, which is present in dairy products and ruminant fat, the biological effects of CLA generally have been studied using mixtures in whi...

journal_title：Lipids

authors： Sébédio JL,Angioni E,Chardigny JM,Grégoire S,Juanéda P,Berdeaux O

更新日期：2001-06-01 00:00:00

abstract：:Oxidized low density lipoprotein (Ox-LDL) is a well-established risk factor in atherosclerosis and lysophosphatidylcholine (LysoPtdCho) is considered to be one of the major atherogenic component of Ox-LDL. The purpose of this work was to investigate the effects of two membrane n-3 long chain polyunsaturated fatty acid...

journal_title：Lipids

authors： Tardivel S,Gousset-Dupont A,Robert V,Pourci ML,Grynberg A,Lacour B

更新日期：2009-03-01 00:00:00

abstract：:Phytophthora species are eukaryotic sterol auxotrophs that possess the ability to grow, albeit poorly, in the complete absence of sterols. Growth of Phytophthora is often improved substantially when an exogenous source of sterol is provided. Additionally, sterols may be required for sexual and asexual sporulation in P...

journal_title：Lipids

authors： Dotson WD,Tove SR,Parks LW

更新日期：2000-03-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:The seed oil ofEuonymus verrucosus Scop., family Celastraceae, contains more than 90% 1,2-diacyl-3-acetins (monoacetotriglycerides). The constituent triglyceride acids, other than acetic, are the usual long-chain fatty acids.Thin-layer chromatography (TLC), infrared (IR) and hydrolysis with pancreatic lipase indicate ...

journal_title：Lipids

authors： Kleiman R,Miller RW,Earle FR,Wolff IA

更新日期：1967-11-01 00:00:00

abstract：:Several ions in the mass spectra of wax esters were related to the molecular structures. Assigned structures of ions were confirmed by deuterium labeling. A simple, direct method for quantititive analyses of mixtures was developed. The method involved a comparison of sets of three ions, RCO2H(+), RCO2H2 (+) and [R'-1]...

journal_title：Lipids

authors： Aasen AJ,Hofstetter HH,Iyengar BT,Holman RT

更新日期：1971-07-01 00:00:00

abstract：:With the passage of the U.S. Dietary Supplement Health and Education Act of 1994, dehydroepiandrosterone (DHEA, 5-androsten-3beta-ol-17-one) has become widely available, and a large and growing market has developed for this "fountain of youth." DHEA has been shown to have significant beneficial effects in animals, whi...

journal_title：Lipids

authors： Williams JR

更新日期：2000-03-01 00:00:00

abstract：:This study investigates the protective effect of N-stearoylethanolamine (NSE), a bioactive N-acylethanolamine , on the lipid profile distribution in the pancreas of obesity-induced insulin resistant (IR) rats fed with prolonged high fat diet (58% of fat for 6 months). The phospholipid composition was determined using ...

journal_title：Lipids

authors： Onopchenko OV,Kosiakova GV,Oz M,Klimashevsky VM,Gula NM

更新日期：2015-01-01 00:00:00

abstract：:The monoazaaromatics, pyridine (1), hexyl nicotinate (2), and quinoline (3) and diazaaromatics, pyrimidine (4) and purine (5), readily act as photo-initiators for the peroxidation of methyl linoleate in 0.50 M SDS at 37 degrees C giving free radical chain oxidations of linoleate. Quantitative kinetic runs on the order...

journal_title：Lipids

authors： Barclay LR,Crowe E,Edwards CD

更新日期：1997-03-01 00:00:00

abstract：:The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

journal_title：Lipids

authors： Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

更新日期：2019-09-01 00:00:00

abstract：:Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

journal_title：Lipids

authors： Kim HY,Hamilton J

更新日期：2000-02-01 00:00:00

abstract：:The effects of increasing concentrations of eicosapentaenoic acid (20:5n-3; EPA) and oleic acid (18:1n-9; OA) on esterification to triacylglycerols (TG) and phospholipids (PL), and the relationship to formation and secretion of the very low density lipoproteins (VLDL) were compared in the isolated perfused rat liver. ...

journal_title：Lipids

authors： Zhang ZJ,Wilcox HG,Castellani L,Fungwe TV,Elam MB,Heimberg M

更新日期：1993-05-01 00:00:00

abstract：:Recently, a number of inhibitors of the enzyme oxidosqualene cyclase (OSC; EC 5.4.99.7), a key enzyme in sterol biosynthesis, were shown to inhibit in mammalian cells the multiplication of Trypanosoma cruzi, the parasite agent of Chagas' disease. The gene coding for the OSC of T. cruzi has been cloned and expressed in...

journal_title：Lipids

authors： Oliaro-Bosso S,Ceruti M,Balliano G,Milla P,Rocco F,Viola F

更新日期：2005-12-01 00:00:00

abstract：:The term "conjugated linoleic acid" (CLA) refers to a group of positional and geometric isomers that are derived from linoleic acid and are found primarily in meat and milk products from ruminant animals. Due to the array of putative benefits associated with various forms of CLA, there has been recent interest in supp...

journal_title：Lipids

authors： Mosley SA,Shahin AM,Williams J,McGuire MA,McGuire MK

更新日期：2007-08-01 00:00:00

abstract：:After intravenous injection of liposomes prepared from egg yolk phospholipids into rabbits, the phospholipids were readily assimilated by the lipoproteins, and there were increases in the circulating levels of cholesterol and phospholipids. The increases in cholesterol level were mainly due to increases of free choles...

journal_title：Lipids

authors： Mendez AJ,He JL,Huang HS,Wen SR,Hsia SL

更新日期：1988-10-01 00:00:00

abstract：:A new triterpene alcohol was isolated fron shea butter and its structure was shown to be 24-methylenelanost-9(11)-en-3beta-ol. Gas chromatographic correlations between this triterpene alcohol and other related compounds are discussed. ...

journal_title：Lipids

authors： Itoh T,Tamura T,Matsumoto T

更新日期：1975-08-01 00:00:00

abstract：:Hydrolysis of symmetrical acetylenic TG of type AAA [viz., glycerol tri-(4-decynoate), glycerol tri-(6-octadecynoate), glycerol tri-(9-octadecynoate), glycerol tri-(10-undecynoate), and glycerol tri-(13-docosynoate)] in the presence of eight microbial lipases was studied. Novozyme 435 (Candida antarctica), an efficien...

journal_title：Lipids

authors： Jie MS,Fua X,Lau MM,Chye ML

更新日期：2002-10-01 00:00:00

abstract：:Fecal bile acid and neutral sterol patterns were studied in eight healthy adult volunteers who were challenged with Vibrio cholerae classical Ogawa 395 strain in the course of vaccine development studies. Bacterial 7 alpha-dehydroxylation of cholic and chenodeoxycholic acids was not altered during experimentally induc...

journal_title：Lipids

authors： Huang CT,Levine MM,Daoud GS,Nalin DR,Nichols BL

更新日期：1982-09-01 00:00:00

abstract：:(8R)-Hydroperoxy-(9Z,12Z)-octadecadienoic acid (8-HPODE) is formed by aspergilli as an intermediate in biosynthesis of oxylipins with effects on sporulation. 8-HPODE is transformed by separate diol synthases to (5S,8R)-dihydroxy- and (8R,11S)-dihydroxy-(9Z,12Z)-octadecadienoic acids (5,8- and 8,11-DiHODE). The former ...

journal_title：Lipids

authors： Jernerén F,Oliw EH

更新日期：2012-07-01 00:00:00

abstract：:Considerable progress has been made in the selection and characterization of mutants that are defective in the synthesis of ergosterol in the yeast, Saccharomyces cerevisiae. Mutations in nearly every step of the yeast sterol biosynthetic pathway have been induced and selected. These mutants have been used to elucidat...

journal_title：Lipids

authors： Parks LW,Smith SJ,Crowley JH

更新日期：1995-03-01 00:00:00

abstract：:The effect of lecithin on jejunal absorption of fatty acids and octadecenoylglycerol was studied in healthy volunteers with a jejunal perfusion system which excluded pancreatic and biliary secretions from the test segment. Lecithin significantly reduced the absorption of oleic acid (P less than 0.05) and octadecenoylg...

journal_title：Lipids

authors： Ammon HV,Thomas PJ,Phillipis SF

更新日期：1979-04-01 00:00:00

abstract：:The effect of apo very low density lipoprotein (apo VLDL) and apoprotein C-II on the phospholipase A1 activity associated with lipoprotein lipase (E.C.3.1.1.3) was studied using purified bovine milk lipoprotein lipase. The enzyme degraded 14C phosphatidylcholine (PC) to 14C 2-acyl lysophosphatidylcholine at a rate of ...

journal_title：Lipids

authors： Stocks J,Galton DJ

更新日期：1980-03-01 00:00:00

abstract：:Serum high density lipoprotein is increasingly recognized as a negative risk for cardiovascular disease. The distribution and interrelationship of serum lipids, lipoproteins, anthropometric measurements and blood pressures were determined in some 5,000 children. Children had mean +/- S.D. alpha-lipoprotein cholesterol...

journal_title：Lipids

authors： Berenson GS,Srinivasan SR,Frerichs RR,Webber LS

更新日期：1979-01-01 00:00:00

abstract：:Bile acids solubilize proteins from liver plasma membrane both in vivo and in vitro. The ability to solubilize the proteins is dependent on the species of bile acid. In this paper, the effect of phospholipid on the solubilization of a membrane-bound enzyme by bile acids was investigated in vitro. Taurocholate (TC) and...

journal_title：Lipids

authors： Nokubo M

更新日期：1987-01-01 00:00:00

abstract：:It has been shown that different lysophosphatidylcholines (LPC) possess relaxing properties in vascular strips. We report on the effect of intraatrial injection of LPC micelles into white New Zealand rabbits. Changes in renal and coronary flow were determined by radioactive microspheres. Coronary blood flow increased ...

journal_title：Lipids

authors： Wolf A,Saito T,Dudek R,Bing RJ

更新日期：1991-03-01 00:00:00

abstract：:The relationship between the biosynthesis of long-chain fatty acids and their distribution in the key organs of hypertension is of considerable interest because of their role in the production of vasoactive eicosanoids and their effects on membrane properties. The present study analyzed the fatty acid compositions of ...

journal_title：Lipids

authors： Delachambre MC,Narce M,Asdrubal P,Poisson JP

更新日期：1998-08-01 00:00:00

abstract：:Ceramides are a family of signalling lipids with diverse physiological functions that include pro-differentiative and pro-apoptotic signalling. Ceramides and their derivatives are major constituents of myelin, maintaining neuronal conductivity. Ceramides are synthesized by ceramide synthases, of which there are six is...

journal_title：Lipids

authors： Couttas TA,Lim XY,Don AS

更新日期：2015-01-01 00:00:00