The effects of dehydroepiandrosterone on carcinogenesis, obesity, the immune system, and aging.

abstract：:Vegetable oils are one of the main agricultural commodities. Demand has been increasing steadily over the last five decades and, with finite land available, it is vital that we increase productivity. My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylgl...

journal_title：Lipids

authors： Harwood JL

更新日期：2020-09-01 00:00:00

abstract：:Usually, the chemical structures of cerebrosides in sea creatures are more complicated than those from terrestrial plants and animals. Very little is known about the method for high-throughput molecular profiling of cerebrosides in sea cucumbers. In this study, cerebrosides from four species of edible sea cucumbers, s...

journal_title：Lipids

authors： Jia Z,Cong P,Zhang H,Song Y,Li Z,Xu J,Xue C

更新日期：2015-07-01 00:00:00

abstract：:We have reported previously that platelet-activating factor (PAF) interacts with the neuronal cell line NG108-15 (neuroblastoma X glioma hybrid) and the pheochromocytoma cell line, PC12. PAF acts on these cells by raising levels of intracellular free calcium ions. In the present report, we extend these studies. PAF in...

journal_title：Lipids

authors： Kornecki E,Ehrlich YH

更新日期：1991-12-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor alpha (PPARalpha) belongs to the nuclear receptor superfamily that regulates multiple target genes involved in lipid metabolism. Cholesterol ester transfer protein (CETP) is a secreted glycoprotein that modifies high-density lipoprotein (HDL) particles. In humans, plasma CETP...

journal_title：Lipids

authors： Beyer TP,Chen Y,Porter RK,Lu D,Schmidt RJ,Mantlo NB,Konrad RJ,Cao G

更新日期：2008-07-01 00:00:00

abstract：:The sciatic nerve of rats fed sunflower oil (6 mg 18:3-n-3/100 g of diet) presented dramatic alterations in the long chain polyunsaturated fatty acids in comparison with those fed soy oil (130 mg 18:3n-3/100 g of diet). In both 15-day-old and 60-day-old animals fed sunflower oil, 22:6n-3 (cervonic acid) was four-fold ...

journal_title：Lipids

authors： Bourre JM,Youyou A,Durand G,Pascal G

更新日期：1987-07-01 00:00:00

abstract：:Gallstone formation and dissolution were studied in a prairie dog model of cholesterol (CH) cholelithiasis. Gallstones were induced in 49 prairie dogs by feeding 1.2% CH in a nutritionally adequate semisynthetic diet for 6 wk (period 1). At 6 wk, gallstones had developed in all animals examined. The diets were modifie...

journal_title：Lipids

authors： Cohen BI,Mosbach EH,McSherry CK,Rzigalinski B,Kuroki S

更新日期：1986-09-01 00:00:00

abstract：:Policosanol is a poorly absorbed nutritional supplement used primarily for cholesterol management. Findings from previous trials evaluating the effects of policosanol are mixed with early data reporting positive lipid effects while more recent studies indicate negligible efficacy. We hypothesized that re-formulating p...

journal_title：Lipids

authors： Backes JM,Gibson CA,Ruisinger JF,Moriarty PM

更新日期：2011-10-01 00:00:00

abstract：:Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

journal_title：Lipids

authors： Kim HY,Hamilton J

更新日期：2000-02-01 00:00:00

abstract：:Rainbow trout (Oncorhynchus mykiss) weighing ca. 5 g and previously acclimated for 8 wk on a diet comprising vegetable oil (11%), fish meal (5%), and casein (48%) as the major constituents were fed a pulse of diet containing deuterated (D5) (17,17,18,18,18)-18:3n-3 ethyl ester. The synthesis and tissue distribution of...

journal_title：Lipids

authors： Bell MV,Dick JR,Porter AE

更新日期：2001-10-01 00:00:00

abstract：:The degradation of exogenous radioactively labeled fatty acids by 5-day-old barley shoots was examined. [1-(14)C] Linoleic acid was observed to be degraded 7 times faster than [1-(14)C] oleic acid and 5 times faster than [1-(14)C] palmitic acid. The pathway of degradation was determined by identifying the water-solubl...

journal_title：Lipids

authors： Nabors LA,Morgan MS,Newman DW,Jaworski JG

更新日期：1984-07-01 00:00:00

abstract：:A new spectrophotometric assay for determining the activity of acylglycerol hydrolases (lipases, E.C. 3.1.1.3) was developed and optimized for yeast lipase (Candida cylindracea). Studies with porcine pancreatic lipase were also conducted and the influence of various detergents and divalent cations on the assay was eva...

journal_title：Lipids

authors： Rogel AM,Stone WL,Adebonojo FO

更新日期：1989-06-01 00:00:00

abstract：:Dysregulation of adipokines is a hallmark of obesity. Polyunsaturated fatty acids in fish oil may exert anti-inflammatory effects on adipose tissue mitigating the dysregulation of adipokines thereby preventing obesity. This study investigated the effects of high-fat diets containing different amounts of n3 polyunsatur...

journal_title：Lipids

authors： Sundaram S,Bukowski MR,Lie WR,Picklo MJ,Yan L

更新日期：2016-05-01 00:00:00

abstract：:The total lipids, total neutral lipids, and total phospholipids from Aedes aegypti and aedes albopictus cells cultivated in vitro in a medium containing fetal calf serum were analyzed. The mosquito cells were harvested in the logarithmic and stationary phases of growth. The fatty acid profiles of the lipids showed dif...

journal_title：Lipids

authors： McMeans E,Yang TK,Anderson LE,Jenkin HM

更新日期：1975-02-01 00:00:00

abstract：:The gut microbiota is proposed as a "metabolic organ" involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on host metabolism and gut microbiota. In the present study, we examined the ...

journal_title：Lipids

authors： Shang Y,Khafipour E,Derakhshani H,Sarna LK,Woo CW,Siow YL,O K

更新日期：2017-06-01 00:00:00

abstract：:In the present study, changes in phospholipid compositions of liver microsomes, erythrocyte membranes, platelets, aorta, cardiac muscle and brain of rats fed olive oil were compared with those of rats fed sunflower oil. Four groups of rats starting at weaning were fed for four weeks a basal diet containing 5 or 25% ol...

journal_title：Lipids

authors： Navarro MD,Periago JL,Pita ML,Hortelano P

更新日期：1994-12-01 00:00:00

abstract：:Mycobacterium fortuitum utilizes certain stereoisometric mixtures of individual multimethyl branched alkanes as sole carbon source, including 2,6(R), 10(S), 14(RS)-tetramethylhexadecane; 2.6(R), 10(S), 14(RS)-tetramethylheptadecane; 2,6(RS), 10(RS)-trimethyltetradecane, and 2,6(R), 10(S)-trimethylpentadecane. Products...

journal_title：Lipids

authors： Cox RE,Maxwell JR,Myers RN

更新日期：1976-01-01 00:00:00

abstract：:Phosphatidylinositol (PtdIns) and phosphatidylinositol 4-phosphate (PtdIns4P) kinase activities in plasma membranes isolated from canine left ventricle were partially characterized, and their sensitivity to a number of intracellular variables was established. PtdIns and PtdIns4P kinase activities were estimated by the...

journal_title：Lipids

authors： Kasinathan C,Xu ZC,Kirchberger MA

更新日期：1989-09-01 00:00:00

abstract：:Recently, significant differences between rats fed a casein diet and rats fed a soybean protein diet have been observed in hepatic phospholipid fatty acid patterns (Sjöblom, L., and Eklund, A., Biochim. Biophys. Acta 1004, 187-192, 1990). The influence of these two diets on the delta 6 desaturase activity was investig...

journal_title：Lipids

authors： Lindholm M,Eklund A

更新日期：1991-02-01 00:00:00

abstract：:The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

journal_title：Lipids

authors： Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

更新日期：1981-10-01 00:00:00

abstract：:Docosahexaenoic acid (DHA), a prominent long-chain fatty acid of the omega-3 family, is present at high amount in brain tissues, especially in membrane phospholipids. This polyunsaturated fatty acid is the precursor of various oxygenated lipid mediators involved in diverse physiological and pathophysiological processe...

journal_title：Lipids

authors： Jouvène C,Fourmaux B,Géloën A,Balas L,Durand T,Lagarde M,Létisse M,Guichardant M

更新日期：2018-01-01 00:00:00

abstract：:This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collag...

journal_title：Lipids

authors： Oikawa D,Nakanishi T,Nakamura Y,Takahashi Y,Yamamoto T,Shiba N,Tobisa M,Takagi T,Iwamoto H,Tachibana T,Furuse M

更新日期：2003-06-01 00:00:00

abstract：:The combustion method has been modified to increase the recovery of tritiated water after combustion of a tritium-labeled tissue sample. This was accomplished by cooling the bottom of the combustion flask in a dry ice-acetone bath while irradiating the top with an infrared lamp. The procedure resulted in at least 92% ...

journal_title：Lipids

authors： Parekh CK,Eigen E

更新日期：1968-05-01 00:00:00

abstract：:Carbohydrate response element binding protein (ChREBP) regulates insulin-independent de novo lipogenesis. Recently, a novel ChREBPβ isoform was identified. The purpose of the current study was to define the effect of dietary carbohydrates (CHO) and obesity on the transcriptional activity of ChREBP isoforms and their r...

journal_title：Lipids

authors： Stamatikos AD,da Silva RP,Lewis JT,Douglas DN,Kneteman NM,Jacobs RL,Paton CM

更新日期：2016-01-01 00:00:00

abstract：:Starting at 21 days of age, groups of six rats each were fed a basal Torula yeast diet supplemented with 0.4% L-methionine and varying amounts of vitamin E as dl-alpha tocopherol acetate, selenium as sodium selenite, and with either 10% stripped corn oil, stripped lard, or coconut oil. By 7 wk, pentane production by r...

journal_title：Lipids

authors： Dillard CJ,Litov RE,Tappel AL

更新日期：1978-06-01 00:00:00

abstract：:Obesity and type 2 diabetes have reached epidemic proportions in the United States. It is well-established that increasing physical activity plays an important role in reducing risk of obesity and diabetes. Few studies, however, have examined the association between sedentary behaviors such as prolonged television (TV...

journal_title：Lipids

authors： Hu FB

更新日期：2003-02-01 00:00:00

abstract：:CLA has a range of biological properties, including effects on lipid metabolism and body composition in experimental animals. The prevalent isomer of CLA found in the human diet is 9c,11 t-CLA, and it is predominantly found in products containing fat from ruminant animals. This study investigated the effect of dietary...

journal_title：Lipids

authors： Hayman A,MacGibbon A,Pack RJ,Rutherfurd K,Green JH

更新日期：2002-07-01 00:00:00

abstract：:The farnesoid X receptor (FXR, NR1H4) has been recognized as an attractive therapeutic target because it is a nuclear hormone receptor that controls the expression level of cholesterol-7alpha-hydroxylase, which in turn regulates bile acid production and cholesterol excretion. To compare receptor activity between each ...

journal_title：Lipids

authors： Cho KH,Park JY,Han JI,Jeong TS

更新日期：2003-11-01 00:00:00

abstract：:The effect of dexamethasone on the incorporation and conversion of [1-14C]eicosa-8,11,14-trienoic acid to arachidonic acid in isolated hepatocytes and in hepatoma tissue culture (HTC) cells was studied. In both kinds of cells, no changes in the exogenous acid incorporation were found when the hormone was added to the ...

journal_title：Lipids

authors： Marra CA,de Alaniz MJ,Brenner RR

更新日期：1986-03-01 00:00:00

abstract：:Subcellular membranes were analyzed for their lipid composition and protein content at two developmental points representing the third instar wandering larvae and prepupal stages of Drosophila. At both stages, phosphatidylethanolamine (PE) and phosphatidylcholine (PC) were the major constituents with phosphatidylinosi...

journal_title：Lipids

authors： Jones HE,Harwood JL,Bowen ID,Griffiths G

更新日期：1992-12-01 00:00:00

abstract：:Cholesterol and cholesteryl esters were separated according to their carbon number and number of double bonds by high performance reversed-phase chromatography (HPRC) using acetonitrile/chloroform/methanol (1:1:1, v/v) as a mobile phase. It was found that within the same equivalent carbon number (ECN) category, choles...

journal_title：Lipids

authors： Perkins EG,Hendren DJ,Bauer JE,El-Hamdy AH

更新日期：1981-08-01 00:00:00