Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis.

abstract：:A specific radioimmunoassay for platelet-activating factor (PAF) sensitive in the range 10-1000 pg (0.02-2 pmoles) has been developed. Detailed quantitative hapten inhibition studies showed specificity for the acetyl group at C-2 of PAF, a requirement for the ether linkage at C-1 and some tolerance for substituents on...

journal_title：Lipids

authors： Baldo BA,Smal MA,McCaskill AC

更新日期：1991-12-01 00:00:00

abstract：:Choline is an essential nutrient required for the biosynthesis of membrane lipid phosphatidylcholine (PtdCho). Here we elucidate the mechanism of how palmitic acid (PAM) and oleic acid (OLA) regulate choline transporter-like protein 1 (CTL1/SLC44A1) function. We evaluated the mechanism of extracellular and intracellul...

journal_title：Lipids

authors： Schenkel LC,Bakovic M

更新日期：2014-08-01 00:00:00

abstract：:Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...

journal_title：Lipids

authors： Bhatt DP,Rosenberger TA

更新日期：2014-07-01 00:00:00

abstract：:The influence of diet on the kinetics of the overt form of rat liver mitochondrial carnitine palmitoyltransferase (CPT I; EC 2.3.1.21) was studied using rats fed either a low-fat diet (3% w/w fat), or diets which were supplemented with either olive oil (OO), safflower oil (SO) or menhaden (fish) oil (MO) to 20% w/w of...

journal_title：Lipids

authors： Power GW,Cake MH,Newsholme EA

更新日期：1997-01-01 00:00:00

abstract：:Exercise training not only improves the plasma lipid profile but also reduces risk of developing coronary heart disease. We investigate whether plasma lipids and high density lipoprotein (HDL) metabolism are affected by aerobic training and whether the high-density lipoprotein cholesterol (HDL-C) levels at baseline in...

journal_title：Lipids

authors： da Silva JL,Maranhão RC,Silva MSM,Dias RG,Freitas FR,Bolani W,Lemos Junior JR,Alves CR,Oliveira PA,Alves GB,Oliveira EM,Negrao CE,Krieger JE,Pereira AC,Silva GA,Souza JP,Vinagre CGC

更新日期：2019-06-01 00:00:00

abstract：:Bioassay-guided fractionation of a collection of Moorea bouillonii from Papua New Guinea led to the isolation of a new alkyl amide, mooreamide A (1), along with the cytotoxic apratoxins A-C and E. The planar structure of 1 was elucidated by NMR spectroscopy and mass spectrometry analysis. Structural homology between m...

journal_title：Lipids

authors： Mevers E,Matainaho T,Allara' M,Di Marzo V,Gerwick WH

更新日期：2014-11-01 00:00:00

abstract：:Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

journal_title：Lipids

authors： Kim HY,Hamilton J

更新日期：2000-02-01 00:00:00

abstract：:Linoleic acid was efficiently converted into the two major components of conjugated linoleic acid, 9Z,11E-octadecadienoic (1a) and 10E,12Z-octadecadienoic acid (1b) using either the superbase (n-butyllithium/potassium tert-butoxide) or by simply refluxing with KOH in 1-butanol. In turn, 1a and 1b were separated from e...

journal_title：Lipids

authors： Chen CA,Lu W,Sih CJ

更新日期：1999-08-01 00:00:00

abstract：:Three groups of male rats were fed either a corn oil-enriched diet (17%, w/w), a salmon oil-enriched diet (12.5%) supplemented with corn oil (4.5%) or a low-fat diet (4.4%) for eight wk to investigate the possible relationships between dietary fatty acids and lipid composition, and prostaglandin E2 level and phospholi...

journal_title：Lipids

authors： Grataroli R,Léonardi J,Charbonnier M,Lafont R,Lafont H,Nalbone G

更新日期：1988-07-01 00:00:00

abstract：:In their diversity, speciation, and sheer numerical superiority, few should question that insects are the dominant life-form on earth. Their utilization of the multifunctional isopentenoids to regulate their life processes is equally diverse. To catalog or even summarize the contribution of isopentenoids in the regula...

journal_title：Lipids

authors： Bowers WS

更新日期：1978-10-01 00:00:00

abstract：:We have studied the effect of various diets on the phospholipid fatty acid composition and in vitro delta 5 desaturase activity of hepatic microsomes derived either from the normal or streptozotocin-induced diabetic rat. The diets studied were the standard rat chow diet and a basal fat-free diet supplemented either wi...

journal_title：Lipids

authors： Dang AQ,Kemp K,Faas FH,Carter WJ

更新日期：1989-10-01 00:00:00

abstract：:In the present paper, problems in connection with assay of the activity of magnesium-dependent rat liver phosphatidate phosphohydrolase (PAP) are discussed. PAP activity is usually measured by following the production of diacylglycerol or inorganic phosphate from the substrate phosphatidate. These two methods may give...

journal_title：Lipids

authors： Stark M,Humble E

更新日期：1996-10-01 00:00:00

abstract：:We have reported previously that platelet-activating factor (PAF) interacts with the neuronal cell line NG108-15 (neuroblastoma X glioma hybrid) and the pheochromocytoma cell line, PC12. PAF acts on these cells by raising levels of intracellular free calcium ions. In the present report, we extend these studies. PAF in...

journal_title：Lipids

authors： Kornecki E,Ehrlich YH

更新日期：1991-12-01 00:00:00

abstract：:Plaques and white matter from brains of multiple sclerosis (MS) patients were analyzed for lipid content, class composition, and fatty acid composition of total lipid, together with the fatty acid composition of plaque glycerophospholipids, and the results were compared with white matter from normal brain. Plaques con...

journal_title：Lipids

authors： Wilson R,Tocher DR

更新日期：1991-01-01 00:00:00

abstract：:Some 1,2- and 1,3-diacyl glycerols (with acyl groups as stearyl, oleyl, linoleyl, or stearolyl) were synthesized by conventional methods. The diacyl glycerols were esterified with 6-bromo-hexanoic acid to give the corresponding bromo-triacylglycerols (of the type AAB and ABA containing a bromo group at the distal part...

journal_title：Lipids

authors： Jie MS,Cheung SW,Ho JC

更新日期：2001-06-01 00:00:00

abstract：:In an attempt to clarify the mechanism of lipid accumulation inMortierella ramanniana var.angulispora, diacylglycerol acyltransferase (DGAT) in the membrane fraction from this fungus was characterized. The enzyme had an optimum pH of 7.0-7.5, and enzyme activity was blocked by SH-reagents. Metal ions were not essentia...

journal_title：Lipids

authors： Kamisaka Y,Yokochi T,Nakahara T,Suzuki O

更新日期：1993-07-01 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT, EC 2.3.1.43) was assayed in vitro in plasma from normal man, rat, rabbit and dog by following the formation of 14C-cholesteryl esters subsequent to labeling the plasma with 14C-cholesterol in vitro. In all species examined, various local anesthetics were found to inhibit LCA...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1980-10-01 00:00:00

abstract：:Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...

journal_title：Lipids

authors： Fajardo VA,McMeekin L,Basic A,Lamb GD,Murphy RM,LeBlanc PJ

更新日期：2013-04-01 00:00:00

abstract：:The fatty acid composition of cerebrosides of developing foetal human brain and regional variations, if any, during intrauterine life were studied. While palmitic and stearic acids were the predominant normal fatty acids throughout intrauterine life, long chain fatty acids, like lignoceric and nervonic acids, which we...

journal_title：Lipids

authors： Rao PS

更新日期：1977-04-01 00:00:00

abstract：:Phosphatidylinositol (PtdIns) and phosphatidylinositol 4-phosphate (PtdIns4P) kinase activities in plasma membranes isolated from canine left ventricle were partially characterized, and their sensitivity to a number of intracellular variables was established. PtdIns and PtdIns4P kinase activities were estimated by the...

journal_title：Lipids

authors： Kasinathan C,Xu ZC,Kirchberger MA

更新日期：1989-09-01 00:00:00

abstract：:The major sterols of the seeds ofBenincasa cerifera, Cucumis sativus, Cucurbita maxima, C. pepo andTrichosanthes japonica and of the mature plant tissues (leaves and stems) ofCitrullus battich, Cucumis sativus andGynostemma pentaphyllum of the family Cucurbitaceae were 24-ethyl-Δ(7)-sterols which were accompanied by s...

journal_title：Lipids

authors： Akihisa T,Thakur S,Rosenstein FU,Matsumoto T

更新日期：1986-01-01 00:00:00

abstract：:A new triterpene alcohol was isolated fron shea butter and its structure was shown to be 24-methylenelanost-9(11)-en-3beta-ol. Gas chromatographic correlations between this triterpene alcohol and other related compounds are discussed. ...

journal_title：Lipids

authors： Itoh T,Tamura T,Matsumoto T

更新日期：1975-08-01 00:00:00

abstract：:A test meal (300 mg casein, 600 mg sucrose, 100 mg corn oil, tracer dose of 9.10(3)H oleic acid) was given to fasting adult rats with intestinal lymph fistulas. One group received an acute oral dose of ethanol (3.2 g/kg body weight) simultaneously with the test meal. Controls received 2.5 ml of water instead of ethano...

journal_title：Lipids

authors： Boquillon M

更新日期：1976-12-01 00:00:00

abstract：:In plants, two pathways are utilized for the synthesis of isopentenyl diphosphate (IPP), the universal precursor for isoprenoid biosynthesis. In this paper we review findings and observations made primarily with tobacco BY-2 cells (TBY-2), which have proven to be an excellent system in which to study the two biosynthe...

journal_title：Lipids

authors： Hemmerlin A,Gerber E,Feldtrauer JF,Wentzinger L,Hartmann MA,Tritsch D,Hoeffler JF,Rohmer M,Bach TJ

更新日期：2004-08-01 00:00:00

abstract：:Normal phase high performance liquid chromatography methods are described for the separation of neutral lipid, fatty acid and five phospholipid classes using spectrophotometric detection at 206 nm. Separations were accomplished in less than 10 min for each lipid class. A mobile phase consisting of hexane/methyltertiar...

journal_title：Lipids

authors： Hamilton JG,Comai K

更新日期：1988-12-01 00:00:00

abstract：:The beta-adrenergic system in cardiac muscle cells is influenced by the n-3 polyunsaturated fatty acid (PUFA) content in cell membranes. This study deals with the specific effect of docosahexaenoic acid (DHA) as compared to other n-3 PUFA, without modification of the arachidonic acid content. Increasing the DHA conten...

journal_title：Lipids

authors： Grynberg A,Fournier A,Sergiel JP,Athias P

更新日期：1996-03-01 00:00:00

abstract：:The effects of growth temperature on the fatty acid compositions of the phosphatidylcholine (PC), phosphatidylethanolamine (PE), and total lipid (TL) fractions of the free-living nematode Caenorhabditis elegans were investigated. A reduction in growth temperature from 25 to 15 degrees C caused the proportions of eicos...

journal_title：Lipids

authors： Tanaka T,Ikita K,Ashida T,Motoyama Y,Yamaguchi Y,Satouchi K

更新日期：1996-11-01 00:00:00

abstract：:In order to determine the minimal amount of dietary 9-trans, 12-trans-linoleate which can decrease endoperoxide metabolites synthesized and their precursor in rat platelets, graded amounts (0, 0.1, 0.5, 1.0, 2.5%) of the trans-linoleate were fed to rats with a constant amount of all-cis-linoleate (2.5%) for 12 weeks. ...

journal_title：Lipids

authors： Hwang DH,Chanmugam P,Anding R

更新日期：1982-04-01 00:00:00

abstract：:This review explores the effects of dietary long chain polyunsaturated fatty acids (LCPUFA) on various aspects of early immune development and their potential role in the development or the prevention of immune disease. Modern diets have become increasingly rich in n-6 LCPUFA and relatively n-3 LCPUFA deficient. These...

journal_title：Lipids

authors： Prescott SL,Dunstan JA

更新日期：2007-09-01 00:00:00

abstract：:Dysregulation of adipokines is a hallmark of obesity. Polyunsaturated fatty acids in fish oil may exert anti-inflammatory effects on adipose tissue mitigating the dysregulation of adipokines thereby preventing obesity. This study investigated the effects of high-fat diets containing different amounts of n3 polyunsatur...

journal_title：Lipids

authors： Sundaram S,Bukowski MR,Lie WR,Picklo MJ,Yan L

更新日期：2016-05-01 00:00:00