解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Neurons in the hypothalamic arcuate nucleus (arcuate neurons) were traced on Golgi-impregnated sections. Dendrites of arcuate neurons showed characteristic orientation patterns. Dendrites along the lateral side follow the convex border of the nucleus by running parallel to the tanycyte processes. Neurons located in th...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90005-3
更新日期:1985-10-01 00:00:00
abstract::The effect of the availability of synaptic targets on neuronal survival was tested by explanting the cochleovestibular ganglion from embryonic day 3-1/2 chick embryos and maintaining it in the presence or absence of appropriate synaptic target tissues for 14 days in culture. The targets were the inner ear, peripherall...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90053-3
更新日期:1985-09-01 00:00:00
abstract::This immunocytochemical study, using a double-staining method, showed that calcitonin gene-related peptide-like immunoreactive structures are widely distributed in the peripheral nervous system and that many of them coexist with substance P-like immunoreactive structures in single sensory ganglion cells. Neurons posit...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90265-9
更新日期:1985-08-01 00:00:00
abstract::During postnatal development, clusters of cells associated with the mononuclear phagocytic system appear within the white matter of rodents and cats. We studied the distribution and morphology of these cells in the hamster's brain during the first 2 weeks after birth. In animals of different ages, horseradish peroxida...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90263-5
更新日期:1985-08-01 00:00:00
abstract::New dopaminergic terminal fields have been visualized in the rat cerebral neocortex, using two morphological methods based on distinct properties of the dopaminergic system: presence of the first synthetic enzyme, tyrosine hydroxylase, and high-affinity uptake of amines. Tyrosine hydroxylase was used as an immunocytoc...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90248-9
更新日期:1985-08-01 00:00:00
abstract::A reappraisal of the relationship between length summation and receptive field length assessed by the minimum response field method, was made in complex cells recorded from the lightly anaesthetized feline striate cortex. This relationship has previously been proposed by Gilbert [(1977) J. Physiol., Lond. 268, 391-421...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90065-x
更新日期:1985-07-01 00:00:00
abstract::Dopamine stimulates the phosphorylation of the neuron-specific synaptic vesicle proteins Synapsin I, Protein IIIa and Protein IIIb in the posterior pituitary gland of the rat [Tsou and Greengard (1982) Proc. natn. Acad. Sci. U.S.A. 79, 6075-6079]. This effect has been characterized in the present investigation. The st...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90073-9
更新日期:1985-07-01 00:00:00
abstract::The topographical organization of the subnuclear projections towards the thalamus was studied with autographic methods in adult Wistar rats. The four cerebellar deep nuclei give rise to projections to the ventral region of the rostral thalamus. Most of the fibers end contralaterally, according to a topographical patte...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90221-0
更新日期:1985-06-01 00:00:00
abstract::The enzyme choline-O-acetyltransferase catalyses the biosynthesis of acetylcholine from acetyl coenzyme A and choline and is considered as one of the best markers for cholinergic nerve endings. The distribution of this enzymatic activity was analysed during the purification of plasma membranes of purely cholinergic ne...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90235-0
更新日期:1985-06-01 00:00:00
abstract::Microelectrode recordings were made from 5-10 micron dia axons of adult rat spinal cord in vitro. Action potentials in response to electrical stimulation were recorded intracellularly and electrical characteristics of the axons were examined by injecting current pulses through a bridge circuit. All action potentials l...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90118-6
更新日期:1985-05-01 00:00:00
abstract::The distribution of the enzyme protein-O-carboxylmethyltransferase (EC 2.1.1.24) has been investigated in the rat brain using both immunohistochemical and biochemical techniques. The enzyme, which carboxylmethylates free aspartic and glutamic acid residues of protein substrates, was localized in neurons, but not other...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90130-7
更新日期:1985-05-01 00:00:00
abstract::With the six convulsants studied (Soman, intrahippocampal penicillin, bicuculline, pentylenetetrazol, picrotoxin and strychnine), the anatomical distribution of changes in local cerebral glucose utilization was related to the type of seizure observed. Strychnine induced a few very intense motor convulsions during the ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90146-0
更新日期:1985-03-01 00:00:00
abstract::Linear sweep voltammograms recorded with carbon paste electrodes in the striatum of the unanaesthetised, unrestrained rat show three separate peaks. The effect on peak 3 of either unilateral 6-hydroxydopamine lesion of the substantia nigra or intraperitoneal administration of alpha-methyl-paratyrosine, supports our ea...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90140-x
更新日期:1985-03-01 00:00:00
abstract::Blocking activity with intraocular tetrodotoxin prevents the sharpening of the retinotectal map formed during regeneration of the optic nerve. If (under normal conditions) the initially diffuse map sharpens because of correlated activity in neighboring but not distant ganglion cells, then sharpening should also be pre...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90308-2
更新日期:1985-02-01 00:00:00
abstract::Antisera produced in rabbits against pure fractions of cholinergic vesicles from Narcine brasiliensis were used to study cholinergic organelles in rat motor neurons. The indirect immunofluorescence method was used on perfusion-fixed material. The rats were surgically sympathectomized to remove sympathetic adrenergic a...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90314-8
更新日期:1985-02-01 00:00:00
abstract::Intracellular recordings were made from neurones in myenteric ganglia of the guinea-pig ileum in vitro. Synaptic potentials were evoked by electrically stimulating presynaptic fibres as they entered the ganglion, using a small focal electrode. Slow synaptic depolarizations (excitatory postsynaptic potentials) were evo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90317-3
更新日期:1985-02-01 00:00:00
abstract::The central nervous system expresses its function in natural frames of reference. A most conspicuous feature of such frames is their non-orthogonality. Gaze stabilization and, in particular, the sensorimotor transformations performed by the vestibulo-ocular reflex, are prime examples of such general coordinate transfo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90304-5
更新日期:1985-02-01 00:00:00
abstract::Using an indirect immunofluorescence method the distribution of vasoactive intestinal peptide (VIP) immunoreactivity was studied in human foetus and newborn infant spinal cord and dorsal root ganglia. Further, for comparison some newborn infant brains were also investigated. Vasoactive intestinal peptide-like immunore...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90173-3
更新日期:1985-01-01 00:00:00
abstract::A multicompartment passive electrotonic computer model is constructed for the cerebellar Purkinje cell of the guinea-pig. The model has 1089 coupled compartments to accurately represent the morphology of the Purkinje cell. In order that the calculated behavior of the model fit the published electrophysiological observ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90168-x
更新日期:1985-01-01 00:00:00
abstract::The neurosensory cells of the primary olfactory and vomeronasal projections are in a state of continuous replacement throughout adult life. Since their axons form synaptic terminals with neurons in the olfactory and accessory olfactory bulbs, this system is an apparent exception to the rule that peripheral axons canno...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(85)90176-9
更新日期:1985-01-01 00:00:00
abstract::The histopathological sequelae of parenteral administration of kainic acid were investigated in immature rats (3-35 days of age). The brains were fixed 1-14 days after the administration of kainate and the damage evaluated by means of argyrophylic (Fink-Heimer, Gallyas or Nauta-Gygax) and Nissl stains. In animals of l...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90289-6
更新日期:1984-12-01 00:00:00
abstract::The purpose of this study was to investigate the effect of dopamine on the function of synapses formed by cholinergic neurons derived from the rat retina. We used an experimental culture system in which rat striated muscle cells served as postsynaptic targets for cholinergic neurons of the retina. This culture system ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90104-0
更新日期:1984-11-01 00:00:00
abstract::Cholecystokinin-like immunoreactivity was investigated with an indirect immunoperoxidase technique in the whole spinal cord with the light microscope and in the dorsal horn with the electron microscope. Intraparenchymal injections of colchicine were performed to allow the detection of cholecystokinin-like immunoreacti...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90102-7
更新日期:1984-11-01 00:00:00
abstract::Interactions of acoustic and somatosensory evoked potentials were studied in the anterior suprasylvian gyrus of the cat. Two kinds of interaction could be observed: occlusion or facilitation. In most cases occlusion was observed. The interactions showed dynamic changes and were susceptible to different kinds of influe...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90084-8
更新日期:1984-11-01 00:00:00
abstract::The main projection neurones of the dorsal cochlear nucleus, termed pyramidal, bipolar or fusiform cells, have an apical dendritic arbor approaching the ependymal surface of the nucleus and a basal arbor oppositely directed. In Golgi-Del Rio-Hortega material these neurones were studied, with the light microscope, in n...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90099-x
更新日期:1984-11-01 00:00:00
abstract::The coordinate representation of the sense of limb orientation was investigated psychophysically by asking subjects to match the orientation of the arm or of the forearm in several different coordinate representations. Movement of all degrees of freedom of one arm was permitted while movement of the other limb was res...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90252-5
更新日期:1984-10-01 00:00:00
abstract::Some of the myelinated axons in rat peripheral nerves possess marked axoplasmic carbonic anhydrase activity [Riley, Ellis and Bain (1982) J. Histochem. Cytochem. 30, 1275-1288; Riley and Lang (1984) J. Hand Surg. 9A, 112-120]. A mixture of reactive and nonreactive neurons was a general observation in cervical, thoraci...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90269-0
更新日期:1984-09-01 00:00:00
abstract::The enkephalin-like immunoreactivity in the retina of chicks has been studied using immunohistochemical and radioimmunoassay techniques. The histochemical experiments showed that the immunoreactivity was confined to a subpopulation of amacrine cells in the inner nuclear layer which projected processes into sublaminae ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90272-0
更新日期:1984-09-01 00:00:00
abstract::Capsaicin, a neurotoxin which depletes substance P from primary afferent nerve fibres, was injected systematically into adult guinea pigs. The effects of capsaicin were studied by immunohistochemistry, electron microscopy and radioimmunoassay at times from 5 min to 1 year. Within 5 min after a single injection of caps...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90021-6
更新日期:1984-08-01 00:00:00
abstract::A combined Golgi-electron microscope method was used to study the ultrastructural maturation of synapses on identified pyramidal and multipolar non-pyramidal neurons in the visual cortex of young and adult rabbits. In samples of 10 (time of eye opening), 14, 20 day old and 7 month old animals, fully impregnated pyrami...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90003-4
更新日期:1984-08-01 00:00:00
abstract::The sixth lumbar and first sacral spinal cord segments in the rat contain parasympathetic preganglionic neurons which innervate the pelvic viscera. There have been few studies, however, which have specifically considered the distribution of putative peptide neurotransmitters in these cord segments. The present paper d...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90175-1
更新日期:1984-07-01 00:00:00
abstract::Cellular distribution of creatine kinase BB-isoenzyme and tubulin was investigated immunohistochemically with tissue sections from various areas of the gerbil brain. Both the reaction for creatine kinase BB-isoenzyme and tubulin visualized nerve cell bodies, dendrites and axons. While the reaction for tubulin was simi...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90183-0
更新日期:1984-07-01 00:00:00
abstract::The cytotoxic effects of DL-, D- and L-alpha-aminoadipic acid, a six-carbon homologue of glutamate, were investigated in cell cultures of dissociated postnatal mouse cerebellum. Treatment with alpha-aminoadipic acid resulted in rapid nuclear and cytoplasmic swelling and, after longer periods of exposure, karyopyknosis...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90170-2
更新日期:1984-07-01 00:00:00
abstract::In rats under urethane anaesthesia gamma-aminobutyric acid agonists and uptake blockers were microiontophoretically applied in the pyramidal layer of CA1 and in the apical dendrites using a twin set of multibarrelled micropipettes. Thus, the somatic and dendritic field potentials elicited by commissural stimulation we...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90072-1
更新日期:1984-06-01 00:00:00
abstract::The sensitivity of Purkinje cells to short pulse applications of L-aspartate, L-glutamate and related derivatives in their dendritic fields was tested in normal and staggerer mutant mice using cerebellar slices maintained in vitro. In normal mice, the response of Purkinje cells to L-aspartate and L-glutamate consisted...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90076-9
更新日期:1984-06-01 00:00:00
abstract::The ultrastructure of rat neurohypophyses incubated in vitro was studied to investigate secretion-related changes that may be intrinsic to the isolated neurohypophysis and to establish the morphological integrity of this preparation. Neurohypophyses were incubated for 2 h in an in vitro chamber in medium of low (290 m...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90069-1
更新日期:1984-06-01 00:00:00
abstract::The projections of the nucleus of the diagonal band of Broca and of the substantia innominata to the cerebral cortex were studied in the rat, using the anterograde transport of wheat germ agglutinin conjugated with horseradish peroxidase. Following diagonal band injections, fibers were observed ascending in the septum...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90061-7
更新日期:1984-06-01 00:00:00
abstract::Using antisera raised against neurofilaments and the glial fibrillary acidic protein (GFAP) we have examined the appearance and distribution of neurofilament- and GFAP-like immunoreactivity in the enteric nervous system of rat, mouse and guinea-pig. In whole mounts of the external circular and longitudinal muscle laye...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90153-2
更新日期:1984-05-01 00:00:00
abstract::The effects of hypertonic solutions on the spontaneous and evoked catecholamine release from isolated, perfused cat adrenal glands were studied. Hypertonic solutions enhanced three times the spontaneous release of the amines, but markedly inhibited the release evoked by nicotine (5 microM for 2 min) or high K+ (17.7 m...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90155-6
更新日期:1984-05-01 00:00:00
abstract::The relationship of lumbar dorsal root afferents to lateral motor column motoneurons was studied using anterograde injury filling of dorsal roots and retrograde injury filling of ventral roots with horseradish peroxidase. At the light microscopic level, horseradish peroxidase labelled dorsal root axons were observed t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90206-9
更新日期:1984-04-01 00:00:00