Membrane resistivity estimated for the Purkinje neuron by means of a passive computer model.

abstract：:The cerebellum, which controls coordinated and rapid movements, is a potential target for the deleterious effects of drugs of abuse including cannabis (i.e. marijuana, cannabinoids). Prenatal exposure to cannabinoids has been documented to cause abnormalities in motor and cognitive development, but the exact mechanism...

journal_title：Neuroscience

authors： Shabani M,Hosseinmardi N,Haghani M,Shaibani V,Janahmadi M

更新日期：2011-01-13 00:00:00

abstract：:The sixth lumbar and first sacral spinal cord segments in the rat contain parasympathetic preganglionic neurons which innervate the pelvic viscera. There have been few studies, however, which have specifically considered the distribution of putative peptide neurotransmitters in these cord segments. The present paper d...

journal_title：Neuroscience

authors： Sasek CA,Seybold VS,Elde RP

更新日期：1984-07-01 00:00:00

abstract：:After transection of the sciatic nerve there is a dramatic increase in both galanin/galanin message-associated peptide-like immunoreactivities and preprogalanin messenger RNA levels in rat and mouse lumbar 4 and 5 dorsal root ganglion neurons. There is strong evidence that after nerve injury leukemia inhibitor factor ...

journal_title：Neuroscience

authors： Kerekes N,Landry M,Hökfelt T

更新日期：1999-01-01 00:00:00

abstract：:The calcium binding protein, Calbindin-D28k, is known to be localized within spiny neurons of the matrix of the dorsal striatum, caudate-putamen nuclei. This compartment is also known to contain an abundance of GABAergic neurons and to receive extensive input from excitatory limbic and cortical afferents whose activat...

journal_title：Neuroscience

authors： Pickel VM,Heras A

更新日期：1996-03-01 00:00:00

abstract：:The finding that endogenous tetrahydroisoquinolines may be involved in the etiology of Parkinson's disease suggests that their administration may cause changes resembling those observed in parkinsonian brain. We tested, using a high-performance liquid chromatography method, how single and chronic administration of 1,2...

journal_title：Neuroscience

authors： Antkiewicz-Michaluk L,Romañska I,Papla I,Michaluk J,Bakalarz M,Vetulani J,Krygowska-Wajs A,Szczudlik A

更新日期：2000-01-01 00:00:00

abstract：:Motor effects of bilateral lesions of the globus pallidus induced by quinolinic acid (30 and 60 nmol in 0.5 microl) were investigated in rats. Globus pallidus lesions with 60 nmol quinolinic acid produced a significant reduction of spontaneous motor activity measured by a reduced locomotor activity in an open field an...

journal_title：Neuroscience

authors： Hauber W,Lutz S,Münkle M

更新日期：1998-09-01 00:00:00

abstract：:Types and projections of neurons that received cholinergic, purinergic and other fast excitatory synaptic inputs in myenteric ganglia of the guinea-pig distal colon were identified using combined electrophysiological recording, application of selective antagonists, marker dye filling via the recording microelectrode, ...

journal_title：Neuroscience

authors： Nurgali K,Furness JB,Stebbing MJ

更新日期：2003-01-01 00:00:00

abstract：:Previous studies have demonstrated that human astrocytes express mRNA and receptor protein for group I and II metabotropic glutamate receptors (mGluRs). Whether these receptors can influence the inflammatory and immune response and can modulate the capacity of astrocytes to produce inflammatory cytokines is still uncl...

journal_title：Neuroscience

authors： Aronica E,Gorter JA,Rozemuller AJ,Yankaya B,Troost D

更新日期：2005-01-01 00:00:00

abstract：:Previous research has demonstrated that diabetes induces learning and memory deficits. However, the mechanism of memory impairment induced by diabetes is poorly understood. Dietary fatty acids, especially polyunsaturated fatty acids, have been shown to enhance learning and memory and prevent memory deficits in various...

journal_title：Neuroscience

authors： Jia D,Heng LJ,Yang RH,Gao GD

更新日期：2014-01-31 00:00:00

abstract：:Recombinant human erythropoietin (EPO) has been successfully tested as neuroprotectant in brain injury models. The first large clinical trial with stroke patients, however, revealed negative results. Reasons are manifold and may include side-effects such as thrombotic complications or interactions with other medicatio...

journal_title：Neuroscience

authors： Rahimi Nedjat M,Wähmann M,Bächli H,Güresir E,Vatter H,Raabe A,Heimann A,Kempski O,Alessandri B

更新日期：2013-05-15 00:00:00

abstract：:In reaction time (RT) tasks, presentation of a startling acoustic stimulus (SAS) together with a visual imperative stimulus can dramatically reduce RT while leaving response execution unchanged. It has been suggested that a prepared motor response program is triggered early by the SAS but is not otherwise affected. Mo...

journal_title：Neuroscience

authors： Tresilian JR,Plooy AM

更新日期：2006-10-13 00:00:00

abstract：:The central projections of the rat superior sagittal sinus (SSS) sensory innervation were studied by transganglionic tract tracing techniques. Cholera toxin subunit b (CTb) or wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) was applied on the overlying dura of the SSS and labeled terminations in the b...

journal_title：Neuroscience

authors： Liu Y,Broman J,Edvinsson L

更新日期：2004-01-01 00:00:00

abstract：:The neurochemical and behavioural recovery following unilateral and bilateral lesions of the nucleus basalis was investigated in adult male Wistar rats 20 days and 6 months after surgery. The lesions were made by stereotaxic injections of ibotenic acid. Twenty days after surgery there was a statistically significant c...

journal_title：Neuroscience

authors： Casamenti F,Di Patre PL,Bartolini L,Pepeu G

更新日期：1988-01-01 00:00:00

abstract：:Microglia, the resident tissue macrophages of the central nervous system, have a highly differentiated morphology and do not express many of the antigens typically associated with other tissue macrophages. Activation of microglia is associated with a change in morphology and an increase in their repertoire of antigen ...

journal_title：Neuroscience

authors： Reid DM,Perry VH,Andersson PB,Gordon S

更新日期：1993-10-01 00:00:00

abstract：:The steroid hormone vitamin D has important biological roles in calcium transport, cell growth, and cell differentiation. Its cellular activities are mediated by high affinity interaction with the vitamin D receptor. In brain, autoradiographic, immunohistologic, and messenger RNA expression studies implicate a number ...

journal_title：Neuroscience

authors： Langub MC,Herman JP,Malluche HH,Koszewski NJ

更新日期：2001-01-01 00:00:00

abstract：:Previous research has demonstrated antidepressant-like effects in rodents upon intracerebral inhibition of histone deacetylases (HDACs). Such effects have been reported for local HDAC inhibition in the nucleus accumbens, hippocampus, and amygdala. However, the effect of HDAC inhibition within the medial prefrontal cor...

journal_title：Neuroscience

authors： Covington HE 3rd,Maze I,Vialou V,Nestler EJ

更新日期：2015-07-09 00:00:00

abstract：:In adult rats the mystacial vibrissae were clipped on one side of the snout, and the influence of this sensory deprivation on crossed and uncrossed striatal afferents from the substantia nigra, ventral tegmental area, and retrorubral area was examined with the horseradish peroxidase tract tracing technique. Unilateral...

journal_title：Neuroscience

authors： Steiner H,Weiler HT,Morgan S,Huston JP

更新日期：1992-01-01 00:00:00

abstract：:Recent findings indicate that neurosteroids could act as important keys during the brain development. Fluctuations in neonatal allopregnanolone (AlloP) could result in altered pharmacological properties of the GABA(A) receptor system in adulthood. Recent studies demonstrated that neurosteroids play a critical role in ...

journal_title：Neuroscience

authors： Martín-García E,Darbra S,Pallarés M

更新日期：2008-07-17 00:00:00

abstract：:Huntington's disease is a genetic disease, autosomal and dominant, that induces motor disorders, an inexorable deterioration of higher brain functions and psychiatric disturbances. At present, there are no known therapeutics against Huntington's disease. The Network of European CNS Transplantation and Restoration (NEC...

journal_title：Neuroscience

authors： Peschanski M,Cesaro P,Hantraye P

更新日期：1995-09-01 00:00:00

abstract：:Neuropathic pain resulting from spinal cord injury is often accompanied by maladaptive plasticity of the central nervous system, including the opioid receptor-rich periaqueductal gray (PAG). Evidence suggests that sensory signaling via the PAG is robustly modulated by dopamine D1- and D2-like receptors, but the effect...

journal_title：Neuroscience

authors： Voulalas PJ,Ji Y,Jiang L,Asgar J,Ro JY,Masri R

更新日期：2017-02-20 00:00:00

abstract：:Goal of this manuscript is to investigate whether changes that exist in epileptic brain generating spontaneous seizures are reflected in the pattern of the UP-Down state (UDS) recorded from the neocortex and dentate gyrus. Experiments were carried out on naive and epileptic mice under urethane anesthesia. Local field ...

journal_title：Neuroscience

authors： Bragin A,Benassi SK,Engel J Jr

更新日期：2012-12-06 00:00:00

abstract：:The organization of the claustrocortical system was investigated in rat by means of cortical injections of either lectin-conjugated horseradish peroxidase or retrograde fluorescent tracers. The latter were also employed in cat. Evans Blue, Fast Blue, True Blue, Nuclear Yellow and Diamidino Yellow were used in differen...

journal_title：Neuroscience

authors： Minciacchi D,Molinari M,Bentivoglio M,Macchi G

更新日期：1985-11-01 00:00:00

abstract：:Alzheimer's Disease is the leading neurodegenerative cause of dementia. The pathogenesis is not clearly understood yet, is believed to be the complex interaction between genetic and environmental factors. Consequently vascular risk factors and Apolipoprotein E genotyping are increasingly gaining importance. This study...

journal_title：Neuroscience

authors： Panpalli Ates M,Karaman Y,Guntekin S,Ergun MA

更新日期：2016-06-14 00:00:00

abstract：:Studies were made on the effect of the neuroexcitatory agent kainic acid, microinjected into raphe dorsal nucleus by glass micropipette and an air pressure system in doses ranging from 0.2 to 24.0 nmol (in volumes from 0.05 microliter to 0.47 microliter), on the somatosensory evoked potentials and their cycles of reco...

journal_title：Neuroscience

authors： Moyanova S,Dimov S,Ivanova A

更新日期：1987-07-01 00:00:00

abstract：:To investigate the degree of plasticity of hippocampal neural stem cells from adult mice (mHNSC), we have analyzed their differentiation in co-culture with quail neural crest cells. In mixed culture, mHNSC give rise to several non-neuronal neural crest derivatives, including melanocytes, chondrocytes and smooth muscle...

journal_title：Neuroscience

authors： Alexanian AR,Sieber-Blum M

更新日期：2003-01-01 00:00:00

abstract：:During the early developmental period, long-term potentiation (LTP) can be induced in both vertical and horizontal connections in the rat visual cortex. However, the temporal difference in LTP change between the two pathways during animal development remains unclear. In this study, LTP in vertical (from layer IV to la...

journal_title：Neuroscience

authors： Li DK,Zhang C,Gu Y,Zhang SH,Shi J,Chen XH

更新日期：2017-05-14 00:00:00

abstract：:Nitric oxide synthase is the biosynthetic enzyme for the free radical neurotransmitter nitric oxide. Using an affinity-purified antiserum, nitric oxide synthase was found to be localized to peripheral ocular nerve fibers, related cranial ganglia, and the retina of the rat. In the eye, nitric oxide synthase-like immuno...

journal_title：Neuroscience

authors： Yamamoto R,Bredt DS,Snyder SH,Stone RA

更新日期：1993-05-01 00:00:00

abstract：:The noradrenergic nerve terminals and their vesicle populations have been subject to much ultrastructural research which has served to support and extend data from biochemical analysis and pharmacological-physiological experiments. Although a great deal of information has been collected, there are still many problems ...

journal_title：Neuroscience

authors： Thureson-Klein A

更新日期：1983-10-01 00:00:00

abstract：:Lesioning of thalamic target neurons in the adult rat provokes a resorption of terminal axonal branches of afferent neurons from the dorsal column nuclei. There is, however, no massive neuronal loss in the dorsal column nuclei. In the adult, therefore, the thalamic post synaptic target cells influence primarily the ex...

journal_title：Neuroscience

authors： Marty S,Peschanski M

更新日期：1994-10-01 00:00:00

abstract：:Pairing vagus nerve stimulation (VNS) with movements or sounds can direct robust plasticity in motor or auditory cortex, respectively. The degree of map plasticity is influenced by the intensity and pulse width of VNS, number of VNS-event pairings, and the interval between each pairing. It is likely that these paramet...

journal_title：Neuroscience

authors： Loerwald KW,Buell EP,Borland MS,Rennaker RL 2nd,Hays SA,Kilgard MP

更新日期：2018-09-15 00:00:00