Differentiating adult hippocampal stem cells into neural crest derivatives.

Abstract:

:To investigate the degree of plasticity of hippocampal neural stem cells from adult mice (mHNSC), we have analyzed their differentiation in co-culture with quail neural crest cells. In mixed culture, mHNSC give rise to several non-neuronal neural crest derivatives, including melanocytes, chondrocytes and smooth muscle cells. The data suggest that neural crest cell-derived short-range cues that are recognized across species can instruct adult mHNSC to differentiate into neural crest phenotypes.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Alexanian AR,Sieber-Blum M

doi

10.1016/s0306-4522(02)00994-6

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

1-5

issue

1

eissn

0306-4522

issn

1873-7544

pii

S0306452202009946

journal_volume

118

pub_type

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