Mitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier.

abstract：:Fat, ethanol, and nicotine share a number of properties, including their ability to reinforce behavior and produce overconsumption. To test whether these substances act similarly on the same neuronal populations in specific brain areas mediating these behaviors, we administered the substances short-term, using the sam...

journal_title：Neuroscience

authors： Chang GQ,Karatayev O,Barson JR,Liang SC,Leibowitz SF

更新日期：2014-09-26 00:00:00

abstract：:Parkinson's disease patients who suffer from freezing of gait (PD-FOG) may have sensory and/or perceptual deficits, although they are difficult to disentangle. This study evaluated whether visuospatial perception or self-motion perception were more impaired in PD-FOG, and whether distance estimation errors might be re...

journal_title：Neuroscience

authors： Ehgoetz Martens KA,Ellard CG,Almeida QJ

更新日期：2014-08-22 00:00:00

abstract：:Before movement onset, during the reaction time, excitability of M1 is selectively modulated by somatosensory inputs, only in the movement-related muscle. If a similar mechanism operates before the onset of mental movements, then somatosensory afferent inputs are exploited during cognitive representation of movement. ...

journal_title：Neuroscience

authors： Bonassi G,Bisio A,Lagravinese G,Ruggeri P,Bove M,Avanzino L

更新日期：2019-06-15 00:00:00

abstract：:The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...

journal_title：Neuroscience

authors： Engel AK,Tetzlaff W,Kreutzberg GW

更新日期：1988-02-01 00:00:00

abstract：:Obesity may result from dysfunction of the reward system, especially in the nucleus accumbens (Acb). Based on this hypothesis, many researchers have tested the effect of high-frequency stimulation (HFS) of the Acb shell (Acb-Sh) and/or core (Acb-Co) on ingestive behaviors, but few studies have explored the possible me...

journal_title：Neuroscience

authors： Wei N,Wang Y,Wang X,He Z,Zhang M,Zhang X,Pan Y,Zhang J,Qin Z,Zhang K

更新日期：2015-08-20 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and affects the CNS. Dystrophin is absent in muscle and CNS of both DMD patients and mdx mouse, a model of DMD. While the involvement of vascular compartment in DMD was poorly investigated, some studies suggested a role for mast cells (MC). Tryp...

journal_title：Neuroscience

authors： Nico B,Marzullo A,Corsi P,Vacca A,Roncali L,Ribatti D

更新日期：2004-01-01 00:00:00

abstract：:The nucleus tractus solitarius is a key brain centre involved in the regulation of numerous autonomic functions. The present study has employed in vitro autoradiography and in vivo microdialysis to investigate the presence and function of nicotinic acetylcholine receptors located in the medial nucleus tractus solitari...

journal_title：Neuroscience

authors： Ashworth-Preece M,Jarrott B,Lawrence AJ

更新日期：1998-04-01 00:00:00

abstract：:The endocannabinoid and serotonin systems share a high level of overlap in terms of the physiological processes that they regulate, however, little is known about their functional interactions particularly during adolescence, a vulnerable period for both the development of psychosis and for initiation to substance use...

journal_title：Neuroscience

authors： Zavitsanou K,Wang H,Dalton VS,Nguyen V

更新日期：2010-08-11 00:00:00

abstract：:To investigate whether cholinergic hypofunctions in the brain influence hypothalamic-pituitary-adrenal activity, we examined the effects of cholinergic neurotoxin ethylcholine mustard aziridinium ion on basal and stress-induced levels of corticosterone in rats. Blood sampling from rats following intracerebroventricula...

journal_title：Neuroscience

authors： Endo Y,Yamauchi K,Fueta Y

更新日期：2001-01-01 00:00:00

abstract：:The increase in excitatory outflow from the medial prefrontal cortex is critical to the development of sensitization to amphetamine. There is evidence that psychostimulant-induced changes in dopamine-GABA interactions are key to understanding the behaviorally sensitized response. The objective of this study was to cha...

journal_title：Neuroscience

authors： Morshedi MM,Meredith GE

更新日期：2007-11-09 00:00:00

abstract：:Free radicals have been implicated in a number of pathological conditions. To evaluate the neurophysiological consequences of free radical exposure, slices of hippocampus isolated from guinea-pigs were exposed to hydrogen peroxide which reacts with tissue iron to generate hydroxyl free radicals. Long-term potentiation...

journal_title：Neuroscience

authors： Pellmar TC,Hollinden GE,Sarvey JM

更新日期：1991-01-01 00:00:00

abstract：:Thermal hyperalgesia was induced by UV irradiation of the glabrous skin of the hindpaw of adult female Sprague-Dawley rats. We have recorded single cell activity and studied excitability changes in wide dynamic range neurons in the lumbar spinal segments during the early phase (days 1-3) and late phase (days 5-7) of t...

journal_title：Neuroscience

authors： Urban L,Perkins MN,Campbell E,Dray A

更新日期：1993-11-01 00:00:00

abstract：:Stimulation of the cornea activates neurons in two distinct regions of the spinal trigeminal nucleus: at the transition between trigeminal subnucleus interpolaris and subnucleus caudalis and at the transition between trigeminal subnucleus caudalis and the upper cervical spinal cord as estimated by expression of the im...

journal_title：Neuroscience

authors： Bereiter DA,Bereiter DF,Tonnessen BH,Maclean DB

更新日期：1998-03-01 00:00:00

abstract：:Studies demonstrated that chronic high-dose homocysteine administration induced learning and memory impairment in animals. Atractylenolide III (Aen-III), a neuroprotective constituent of Atractylodis macrocephalae Koidz, was isolated in our previous study. In this study, we investigated potential benefits of Aen-III i...

journal_title：Neuroscience

authors： Zhao H,Ji ZH,Liu C,Yu XY

更新日期：2015-04-02 00:00:00

abstract：:Hippocampal anatomy and network organization are capable to generate drug-resistant temporal lobe epilepsy (TLE) in humans and particularly vulnerable to segmental neuronal cell loss. Surgical hippocampectomy has been proven successful in treatment and available human tissue specimens allow systematic clinico-patholog...

journal_title：Neuroscience

authors： Coras R,Blümcke I

更新日期：2015-11-19 00:00:00

abstract：:We have re-examined in the rat the nuclear localization of the medullary catecholamine-containing cell groups (A1 and A2) and their relation to the vagal motor nuclei using a double labeling method. The vagal nuclei were defined by the retrograde transport of horseradish peroxidase applied to the cervical vagus, and n...

journal_title：Neuroscience

authors： Ritchie TC,Westlund KN,Bowker RM,Coulter JD,Leonard RB

更新日期：1982-06-01 00:00:00

abstract：:Midbrain dopamine neurons in the ventral tegmental area, substantia nigra and retrorubral field play key roles in reward processing, learning and memory, and movement. Within these midbrain regions and admixed with the dopamine neurons, are also substantial populations of GABAergic neurons that regulate dopamine neuro...

journal_title：Neuroscience

authors： Nair-Roberts RG,Chatelain-Badie SD,Benson E,White-Cooper H,Bolam JP,Ungless MA

更新日期：2008-04-09 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective degeneration and death of motoneurons in the spinal cord, brainstem and motor cortex which causes progressive muscle weakness and paralysis. Although the molecular mechanisms causing the disease remain unknown, excitotoxi...

journal_title：Neuroscience

authors： Tolosa L,Mir M,Olmos G,Lladó J

更新日期：2009-02-18 00:00:00

abstract：:The enkephalin-like immunoreactivity in the retina of chicks has been studied using immunohistochemical and radioimmunoassay techniques. The histochemical experiments showed that the immunoreactivity was confined to a subpopulation of amacrine cells in the inner nuclear layer which projected processes into sublaminae ...

journal_title：Neuroscience

authors： Millar TJ,Salipan N,Oliver JO,Morgan IG,Chubb IW

更新日期：1984-09-01 00:00:00

abstract：:Isoflurane preconditioning improved short-term neurological outcome after focal brain ischemia in adult rats. It is not known whether desflurane induces a delayed phase of preconditioning in the brain and whether isoflurane preconditioning-induced neuroprotection is long-lasting. Two months-old Sprague-Dawley male rat...

journal_title：Neuroscience

authors： Li L,Zuo Z

更新日期：2009-12-01 00:00:00

abstract：:Cognitive aging affects episodic memory and executive functions, and these vulnerable domains are postulated to be modulated by endogenous and exogenous estrogen exposures. In midlife and late-life women without dementia, estrogen effects on cognition can be examined through associations with concentrations of serum e...

journal_title：Neuroscience

authors： Henderson VW,Popat RA

更新日期：2011-09-15 00:00:00

abstract：:Using a semihorizontal section plane tangential to the ventral surface of the cerebral peduncle, the authors re-examined cyto-, myelo- and dendroarchitecture, acetylcholinesterase activity, afferent fibers, and efferent projection neurons of the substantia nigra pars reticulata. In the semihorizontal section plane, th...

journal_title：Neuroscience

authors： Tokuno H,Nakamura Y,Kudo M,Kitao Y

更新日期：1990-01-01 00:00:00

abstract：:Intrinsic connectivity networks (ICNs) are composed of spatial components and time courses. The spatial components of ICNs were discovered with moderate-to-high reliability. So far as we know, few studies focused on the reliability of the temporal patterns for ICNs based their individual time courses. The goals of thi...

journal_title：Neuroscience

authors： Wang X,Jiao Y,Tang T,Wang H,Lu Z

更新日期：2013-12-19 00:00:00

abstract：:It is now well established that vestibular information plays an important role in spatial memory processes. Although vestibular lesions induce anxiety in humans, this finding remains controversial in rodents. However, it is possible that anxiety-related behavior is associated with spatial memory impairments after vest...

journal_title：Neuroscience

authors： Machado ML,Lelong-Boulouard V,Smith PF,Freret T,Philoxene B,Denise P,Besnard S

更新日期：2012-08-30 00:00:00

abstract：:Several lines of evidence have demonstrated the presence of three opioid receptor types in the CNS and periphery. These receptors are referred to as mu, delta and kappa, and have been implicated in a wide variety of functions. The present study examines the localization of the kappa 1 receptor, a region of the recepto...

journal_title：Neuroscience

authors： Mansour A,Burke S,Pavlic RJ,Akil H,Watson SJ

更新日期：1996-04-01 00:00:00

abstract：:Review of the normally occurring neuronal patterns of the hippocampus suggests that the two principal cell types of the hippocampus, the pyramidal neurons and granule cells, are maximally active during different behaviors. Granule cells reach their highest discharge rates during theta-concurrent exploratory activities...

journal_title：Neuroscience

authors： Buzsáki G

更新日期：1989-01-01 00:00:00

abstract：:Morphine (opiate agonist) produced a dose-dependent decrease in the spontaneous motility of 5- and 9-day chick embryos. Naloxone (opiate antagonist) appeared to reverse competitively the inhibition of motility caused by morphine. The effects of morphine on spontaneous motility in 5-day embryos were also reversed stere...

journal_title：Neuroscience

authors： Maderdrut JL,Reitzel JL,Okado N,Oppenheim RW

更新日期：1985-10-01 00:00:00

abstract：:Neurons expressing immunoreactivity to antisera against somatostatin 14 and other somatostatin-related peptides were identified in the striatum of cats and nonhuman primates. In each species, immunoreactive neurons were distributed singly and in small groups in the caudate nucleus, putamen and ventral striatum. A deta...

journal_title：Neuroscience

authors： Chesselet MF,Graybiel AM

更新日期：1986-03-01 00:00:00

abstract：:The hypothalamic-pituitary-adrenal (HPA) axis underlies both adaptive and maladaptive responses to stress and may be an important marker of childhood vulnerability to psychopathology, although little is known about genetic variants that influence cortisol reactivity. We therefore examined associations between corticot...

journal_title：Neuroscience

authors： Sheikh HI,Kryski KR,Smith HJ,Hayden EP,Singh SM

更新日期：2013-01-15 00:00:00

abstract：:The coordinate representation of the sense of limb orientation was investigated psychophysically by asking subjects to match the orientation of the arm or of the forearm in several different coordinate representations. Movement of all degrees of freedom of one arm was permitted while movement of the other limb was res...

journal_title：Neuroscience

authors： Soechting JF,Ross B

更新日期：1984-10-01 00:00:00