Glucocorticoid hypersecretion following intracerebroventricular injection of ethylcholine mustard aziridinium ion in rats.

abstract：:The 2-deoxyglucose metabolic mapping technique has been used to investigate the neural mechanisms which underlie the symptoms of Parkinsonism in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson's disease. In six cynomolgus monkeys, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine was either (a) ...

journal_title：Neuroscience

authors： Mitchell IJ,Clarke CE,Boyce S,Robertson RG,Peggs D,Sambrook MA,Crossman AR

更新日期：1989-01-01 00:00:00

abstract：:In order to identify the specific targets of the septohippocampal projection in the rat, horseradish peroxidase localization at the electron microscopic level was used. Following injections of free horseradish peroxidase into the medial septum, sections of the dorsal hippocampal formation were reacted with diaminobenz...

journal_title：Neuroscience

authors： Chandler JP,Crutcher KA

更新日期：1983-11-01 00:00:00

abstract：:Icariin is derived most commonly from the traditional Chinese herb Epimedium brevicornum Maxim. Our previous studies have shown that icariin protects neurons from neurotoxic and ischemic conditions. This study aims to investigate the effect of icariin on the expression of amyloid precursor protein (APP) and the level ...

journal_title：Neuroscience

authors： Li F,Dong HX,Gong QH,Wu Q,Jin F,Shi JS

更新日期：2015-09-24 00:00:00

abstract：:Specific high-affinity neurotensin binding sites were labeled in sections of the rat caudal brainstem using a monoiodinated ligand, and their distribution was examined by light microscopic radioautography after fixation with glutaraldehyde. In the medulla, labeled binding sites were mainly concentrated within the dors...

journal_title：Neuroscience

authors： Kessler JP,Moyse E,Kitabgi P,Vincent JP,Beaudet A

更新日期：1987-10-01 00:00:00

abstract：:A previous study investigating potential adult hippocampal neurogenesis in microchiropteran bats failed to reveal a strong presence of this neural trait. As microchiropterans have a high field metabolic rate and a small body mass, it is possible that capture/handling stress may lead to a decrease in the detectable pre...

journal_title：Neuroscience

authors： Chawana R,Alagaili A,Patzke N,Spocter MA,Mohammed OB,Kaswera C,Gilissen E,Bennett NC,Ihunwo AO,Manger PR

更新日期：2014-09-26 00:00:00

abstract：:Cannabinoid receptor type 1 (CB1)-dependent signaling in the brain is known to modulate food intake. Recent evidence has actually shown that CB1 can both inhibit and stimulate food intake in fasting/refeeding conditions, depending on the specific neuronal circuits involved. However, the exact brain sites where this bi...

journal_title：Neuroscience

authors： Soria-Gómez E,Massa F,Bellocchio L,Rueda-Orozco PE,Ciofi P,Cota D,Oliet SH,Prospéro-García O,Marsicano G

更新日期：2014-03-28 00:00:00

abstract：:Respiratory disturbances are a primary phenotype of the neurological disorder, Rett syndrome (RTT), caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Mouse models generated with null mutations in Mecp2 mimic respiratory abnormalities in RTT girls. Large deletions, however, are see...

journal_title：Neuroscience

authors： Bissonnette JM,Schaevitz LR,Knopp SJ,Zhou Z

更新日期：2014-05-16 00:00:00

abstract：:We investigated the role of cyclic-AMP response element binding protein signaling in the induction of the immediate-early gene c-fos by baroreceptor activation in neurons of the nucleus tractus solitarii of anesthetized rats. Activation of the arterial baroreceptors with sustained hypertension significantly increased ...

journal_title：Neuroscience

authors： Chan JY,Chen WC,Lee HY,Chang TJ,Chan SH

更新日期：1999-01-01 00:00:00

abstract：:Recent in vivo electrophysiological studies suggest that chronic dopamine depletion alters profoundly the firing pattern of basal ganglia neurons. These changes may disrupt the processing of cortical information flow from the striatum to the output nuclei, and presumably underlie the clinical manifestations of Parkins...

journal_title：Neuroscience

authors： Tseng KY,Riquelme LA,Murer MG

更新日期：2004-01-01 00:00:00

abstract：:The effects of glial cell line-derived neurotrophic factor on axonal outgrowth and apoptosis were studied in vitro using explanted dorsal root ganglia-peripheral nerve preparations of adult mice. In gels of matrigel or collagen type 1, glial cell line-derived neurotrophic factor increased both the numbers and lengths ...

journal_title：Neuroscience

authors： Leclere P,Ekström P,Edström A,Priestley J,Averill S,Tonge DA

更新日期：1998-01-01 00:00:00

abstract：:I have prepared a number of monoclonal antibodies to chromaffin cell membranes. One of these antibodies recognizes a number of antigenically related proteins that are present in all tissues examined. In the adrenal, these proteins are completely excluded from chromaffin granules but are present in other subcellular me...

journal_title：Neuroscience

authors： Pruss RM

更新日期：1987-07-01 00:00:00

abstract：:It is well established that transforming growth factor alpha is involved prenatally in development of the nervous system, but its role in the postnatal brain is less well understood. Here, we document the occurrence of late-onset, morphological and behavioral deficits in the naturally occurring murine mutant, Waved-1 ...

journal_title：Neuroscience

authors： Burrows RC,Levitt P,Shors TJ

更新日期：2000-01-01 00:00:00

abstract：:Our series of rat experiments have shown that locomotor activity, arousal level, body and brown adipose tissue temperatures, heart rate and arterial pressure increase episodically in an integrated manner approximately every 100min (ultradian manner). Although it has been proposed that the integrated ultradian pattern ...

journal_title：Neuroscience

authors： Miyata K,Kuwaki T,Ootsuka Y

更新日期：2016-10-15 00:00:00

abstract：:The aim of this study was to assess whether omega conotoxin fraction GVIA, a potent blocker of N- and L-type voltage-sensitive calcium channels, might interfere with reflex responses (micturition, blood pressure rise in spinal rats) produced by activation of capsaicin-sensitive sensory nerves of the rat urinary bladde...

journal_title：Neuroscience

authors： Maggi CA,Giuliani S,Santicioli P,Tramontana M,Meli A

更新日期：1990-01-01 00:00:00

abstract：:The distribution of N-methyl-D-aspartate- (NMDA) and kainic acid- (KA) sensitive ionotropic glutamate receptors (iGluR) in the zebrafish olfactory bulb was assessed using an activity-dependent labeling method. Olfactory bulbs were incubated with an ion channel permeant probe, agmatine (AGB), and iGluR agonists in vitr...

journal_title：Neuroscience

authors： Edwards JG,Michel WC

更新日期：2003-01-01 00:00:00

abstract：:Our light and electron microscopic studies (Seress L., Nitsch R. and Leranth C. (1993) Neuroscience 55, 775-796.) indicated that in the hippocampus of the African Green monkey, calretinin is exclusively present in non-pyramidal cells. Calretinin-positive axons formed a prominent band at the border of the dentate molec...

journal_title：Neuroscience

authors： Nitsch R,Leranth C

更新日期：1993-08-01 00:00:00

abstract：:The origin of the corticothalamic projections to the contralateral mediodorsal nucleus, the collateralization of cortical fibers and their synaptic organization in the ipsi- and contralateral mediodorsal nuclei were investigated in adult rats with double retrograde fluorescent and anterograde tracing. After tracer inj...

journal_title：Neuroscience

authors： Négyessy L,Hámori J,Bentivoglio M

更新日期：1998-06-01 00:00:00

abstract：:Small (SK) and intermediate (IK) conductance calcium-activated potassium channels are candidate ion channels for the regulation of excitability in nociceptive neurones. We have used unique peptide-directed antisera to describe the immunocytochemical distribution of the known isoforms of these ion channels in dorsal ro...

journal_title：Neuroscience

authors： Mongan LC,Hill MJ,Chen MX,Tate SN,Collins SD,Buckby L,Grubb BD

更新日期：2005-01-01 00:00:00

abstract：:Despite extensive investigations into the mechanisms of aerobic respiration in mitochondria, the spontaneous metabolic activity of individual cells within a whole animal has not been observed in real time. Consequently, little is known about whether and how the level of mitochondrial energy metabolism is regulated in ...

journal_title：Neuroscience

authors： Kazama H,Ichikawa A,Kohsaka H,Morimoto-Tanifuji T,Nose A

更新日期：2008-03-03 00:00:00

abstract：:Activities of daily living require simultaneous and coordinated activation of trunk and upper-limb segments, which involves complex interlimb interaction within the central nervous system. Although many studies have reported associations between activity of trunk and limb muscles during functional tasks, evidence on c...

journal_title：Neuroscience

authors： Sasaki A,Milosevic M,Nakazawa K

更新日期：2020-12-15 00:00:00

abstract：:The Tg2576 mouse model of Alzheimer's disease (AD) exhibits age-dependent amyloid beta (Abeta) deposition in the brain. We studied electroencephalographically defined sleep and the circadian regulation of waking activities in Tg2576 mice to determine whether these animals exhibit sleep abnormalities akin to those in A...

journal_title：Neuroscience

authors： Wisor JP,Edgar DM,Yesavage J,Ryan HS,McCormick CM,Lapustea N,Murphy GM Jr

更新日期：2005-01-01 00:00:00

abstract：:Victims of minimal traumatic brain injury (mTBI) do not show clear morphological brain defects, but frequently suffer lasting cognitive deficits, emotional difficulties and behavioral disturbances. In the present study we adopted a non-invasive closed-head weight-drop mouse model to produce mTBI. We examined the effec...

journal_title：Neuroscience

authors： Zohar O,Schreiber S,Getslev V,Schwartz JP,Mullins PG,Pick CG

更新日期：2003-01-01 00:00:00

abstract：:A variety of postmortem brain studies and clinical investigations have provided evidence that reduced serotonin neurotransmission is associated with suicidal behavior and depression, and several serotonergic parameters have been found to be altered in the prefrontal cortex of suicide victims. However, the integrity of...

journal_title：Neuroscience

authors： Austin MC,Whitehead RE,Edgar CL,Janosky JE,Lewis DA

更新日期：2002-01-01 00:00:00

abstract：:Responses to nerve stimulation were recorded with intracellular microelectrodes from neurons in the inferior mesenteric ganglion of the guinea-pig. An event was recorded which was subthreshold for a somatic action potential but which had a short rise time and a rapid initial repolarization that gave the event a small ...

journal_title：Neuroscience

authors： Coleman HA

更新日期：1987-02-01 00:00:00

abstract：:Reflex response of fusimotoneurons to sinusoidal muscle stretching were investigated in decerebrated cats. Nerve impulses of single fusimotoneurons were recorded from thin filaments dissected from otherwise intact nerves to triceps surae muscles. Amplitude of the sinusoidal stretching of these muscles was 3 mm peak-to...

journal_title：Neuroscience

authors： Anastasijević R,Jovanović K,Vuco J

更新日期：1990-01-01 00:00:00

abstract：:By means of antisera to cytoplasmic components of nerve fibres and neuropeptides which are known to be present in sensory or sympathetic nerves we have examined the distribution of both total and different types of nerve fibres in normal and inflamed human synovial tissue. Samples of synovia were obtained at surgery f...

journal_title：Neuroscience

authors： Mapp PI,Kidd BL,Gibson SJ,Terry JM,Revell PA,Ibrahim NB,Blake DR,Polak JM

更新日期：1990-01-01 00:00:00

abstract：:The study of architectonic differentiation in the cortex is advanced by the articulation of objective definitions based on clear features of the cortical architecture. We adopted areal density profiles as a means of sampling the cortex. On the profiles, we isolated and quantified the density of individual cortical lay...

journal_title：Neuroscience

authors： Mackey S,Petrides M

更新日期：2009-03-31 00:00:00

abstract：:Previous studies have identified the ventral and dorsal brain regions that respectively support semantic and non-semantic phonological access. Nevertheless, the specific role of the left occipitotemporal cortex (lOTC) in the two pathways of phonological access is ambiguous. To address that question, the present study ...

journal_title：Neuroscience

authors： Dong J,Lu C,Chen C,Li H,Liu X,Mei L

更新日期：2020-03-15 00:00:00

abstract：:An odorant's code is represented by activity in a dispersed ensemble of olfactory sensory neurons in the nose, activation of a specific combination of groups of mitral cells in the olfactory bulb and is considered to be mapped at divergent locations in the olfactory cortex. We present here an in vitro model of the mam...

journal_title：Neuroscience

authors： Markopoulos F,Neubauer FB,Berger T,Scotti AL

更新日期：2008-10-28 00:00:00

abstract：:Cognitive impairment is one of the common non-motor symptoms in Parkinson's disease (PD). The hippocampus is a critical structure for learning and memory processes. The abnormal synaptic plasticity in the hippocampus is suggested to be associated with cognitive dysfunction in PD. Voltage gated sodium channels (VGSCs) ...

journal_title：Neuroscience

authors： Wang Z,Lin Y,Liu W,Kuang P,Lao W,Ji Y,Zhu H

更新日期：2019-10-15 00:00:00