Cortical and Subcortical Neural Interactions Between Trunk and Upper-limb Muscles in Humans.

Abstract:

:Activities of daily living require simultaneous and coordinated activation of trunk and upper-limb segments, which involves complex interlimb interaction within the central nervous system. Although many studies have reported associations between activity of trunk and limb muscles during functional tasks, evidence on cortical and subcortical contributions to trunk-limb neural interactions is still not fully clear. Therefore, the aim of this study was to examine interactions between trunk and upper-limb muscles in the: (i) corticospinal circuits by using motor evoked potential (MEP) elicited through transcranial magnetic stimulation; and (ii) subcortical circuits by using cervicomedullary motor evoked potential (CMEP) elicited through cervicomedullary junction magnetic stimulation. Responses were evoked in the erector spinae (trunk) and flexor carpi radialis (upper-limb) muscles in twelve able-bodied individuals: (1) while participants were relaxed; (2) during trunk muscle contractions while arms were at rest; and (3) during upper-limb muscle contractions while the trunk was at rest. Our results showed that trunk muscle CMEP responses were not affected by upper-limb muscle contractions, while MEP responses were modulated. This indicates that at least the subcortical circuits may not attribute to facilitation of the trunk muscles during upper-limb contractions. On the other hand, in the upper-limb muscles, both CMEP and MEP responses were modulated during trunk contractions. These results indicate that cortical and subcortical mechanisms attributed to facilitation of upper-limb muscles during trunk contractions. In conclusion, our study demonstrated evidence that trunk-limb neural interactions may be attributed to cortical and/or subcortical mechanisms depending on the contracted muscle.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Sasaki A,Milosevic M,Nakazawa K

doi

10.1016/j.neuroscience.2020.10.011

subject

Has Abstract

pub_date

2020-12-15 00:00:00

pages

126-136

eissn

0306-4522

issn

1873-7544

pii

S0306-4522(20)30658-8

journal_volume

451

pub_type

杂志文章
  • Chemically defined neuron groups and their subpopulations in the glomerular layer of the rat main olfactory bulb--II. Prominent differences in the intraglomerular dendritic arborization and their relationship to olfactory nerve terminals.

    abstract::In the glomerular layer of the rat main olfactory bulb, we previously reported three chemically defined interneuron groups: GABA-like immunoreactive, calretinin-immunoreactive and Calbindin-D28k-immunoreactive groups [Kosaka K. et al. (1995) Neurosci. Res. 23, 73-88]. In the present study, we analysed the structural f...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(96)00308-9

    authors: Kosaka K,Toida K,Margolis FL,Kosaka T

    更新日期:1997-02-01 00:00:00

  • Modulation of presumed cholinergic mesopontine tegmental neurons by acetylcholine and monoamines applied iontophoretically in unanesthetized cats.

    abstract::The mesopontine tegmentum, which contains both cholinergic and non-cholinergic neurons, plays a crucial role in behavioral state control. Using microiontophoresis in unanesthetized cats, we have examined the effect of cholinergic and monoaminergic drugs on two putative cholinergic neurons located mostly in the laterod...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(00)00004-x

    authors: Koyama Y,Sakai K

    更新日期:2000-01-01 00:00:00

  • Modulation of synaptic zinc in barrel cortex by whisker stimulation.

    abstract::The cortical representation of the body surface is not fixed, but rather, is continuously modified by ongoing changes in sensory experience. Although the cellular and molecular mechanisms that subserve these changes are uncertain, increasing evidence suggests that synaptically-released zinc may play a role. Zinc is re...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2005.05.011

    authors: Brown CE,Dyck RH

    更新日期:2005-01-01 00:00:00

  • Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesia.

    abstract::Inflammation and hyperalgesia induce a dramatic up-regulation of opioid messenger RNA and peptide levels in nociceptive neurons of the spinal dorsal horn. Descending axons modulate nociceptive transmission at the spinal level during inflammatory pain, and may play a role in the development of persistent pain. The role...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(98)00204-8

    authors: MacArthur L,Ren K,Pfaffenroth E,Franklin E,Ruda MA

    更新日期:1999-01-01 00:00:00

  • Swimming Physical Training Prevented the Onset of Acute Muscle Pain by a Mechanism Dependent of PPARγ Receptors and CINC-1.

    abstract::Regular physical exercise has been described as a good strategy for prevention or reduction of musculoskeletal pain. The Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) has been investigated as a promising target for the control of inflammatory pain. Therefore, the aim of this study was to evaluate whether ac...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2019.12.017

    authors: de Azambuja G,Botasso Gomes B,Messias LHD,Aquino BM,Jorge CO,Manchado-Gobatto FB,Oliveira-Fusaro MCG

    更新日期:2020-02-10 00:00:00

  • Beta-amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons.

    abstract::A synthetic fragment 31-35 of beta-amyloid peptide was used in cultured cortical neurons to examine whether this smaller sequence could trigger apoptotic degeneration in vitro by using morphological, biochemical and flow-cytometric examinations. The results showed that: (i) neurons treated with fragment 31-35 of beta-...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(98)00727-1

    authors: Yan XZ,Qiao JT,Dou Y,Qiao ZD

    更新日期:1999-01-01 00:00:00

  • Group II and III metabotropic glutamate receptors and the control of the nucleus reticularis thalami input to rat thalamocortical neurones in vitro.

    abstract::Intracellular recordings were made from neurones in the thalamic reticular nucleus (TRN) and ventro-basal (VB) thalamus in slices of rat midbrain in vitro. Electrical stimulation of the medial lemniscus or TRN resulted in the generation of complex synaptic potentials containing disynaptic inhibitory post-synaptic pote...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2003.08.014

    authors: Turner JP,Salt TE

    更新日期:2003-01-01 00:00:00

  • Aging in the cerebellum and hippocampus and associated behaviors over the adult life span of CB6F1 mice.

    abstract::In the present study we examined the effects of normal aging in the hippocampus and cerebellum, as well as behaviors associated with these substrates. A total of 67 CB6F1 hybrid mice were tested at one of five ages (4, 8, 12, 18 or 25 months) on the context pre-exposure facilitation effect (CPFE) modification of fear ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2013.06.002

    authors: Kennard JA,Brown KL,Woodruff-Pak DS

    更新日期:2013-09-05 00:00:00

  • Electrophysiological characteristics of inhibitory neurons of the prepositus hypoglossi nucleus as analyzed in Venus-expressing transgenic rats.

    abstract::The identification and characterization of excitatory and inhibitory neurons are significant steps in understanding neural network functions. In this study, we investigated the intrinsic electrophysiological properties of neurons in the prepositus hypoglossi nucleus (PHN), a brainstem structure that is involved in gaz...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2011.09.017

    authors: Shino M,Kaneko R,Yanagawa Y,Kawaguchi Y,Saito Y

    更新日期:2011-12-01 00:00:00

  • Imaging free zinc in synaptic terminals in live hippocampal slices.

    abstract::Some glutamatergic synapses in the mammalian central nervous system exhibit high levels of free ionic zinc in their synaptic vesicles. The precise role of this vesicular zinc remains obscure, despite suggestive evidence for zinc as a neuromodulator. As a step towards elucidating the role of free zinc in the brain we h...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(96)00695-1

    authors: Budde T,Minta A,White JA,Kay AR

    更新日期:1997-07-01 00:00:00

  • Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression.

    abstract::Melanin-concentrating hormone (MCH) is a hypothalamic neuropeptide that has been implicated in energy homeostasis. Pharmacological studies with MCH and its receptor antagonists have suggested additional behavioral roles for the neuropeptide in the control of mood and vigilance states. These suggestions have been suppo...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2008.08.048

    authors: Willie JT,Sinton CM,Maratos-Flier E,Yanagisawa M

    更新日期:2008-10-28 00:00:00

  • Developmental changes in the expression of calbindin and potassium-channel subunits Kv3.1b and Kv3.2 in mouse Renshaw cells.

    abstract::One class of spinal interneurons, the Renshaw cells, is able to discharge at very high frequencies in adult mammals. Neuronal firing at such high frequencies requires voltage-gated potassium channels to rapidly repolarize the membrane potential after each action potential. We sought to establish the pattern of express...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2005.12.048

    authors: Song ZM,Hu J,Rudy B,Redman SJ

    更新日期:2006-05-12 00:00:00

  • Phenotypic characterization of orofacial movement topography in mutants with disruption of amino acid mechanisms: glutamate N2A/B/D [GluRε1/2/4] subtypes and the GABA synthesizing enzyme GAD65.

    abstract::To investigate the role of glutamate receptor subtypes and GABA in orofacial function, six individual topographies of orofacial movement, both spontaneous and induced by the dopamine D1-like receptor agonist [R/S]-3-methyl-6-chloro-7,8-dihydroxy-1-[3-methyl-phenyl]-2,3,4,5-tetrahydro-1H-3-benzazepine (SKF 83959), were...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2013.07.038

    authors: Tomiyama K,Kato R,Hara Y,Kobayashi M,Mishina M,Yanagawa Y,Kinsella A,Koshikawa N,Waddington JL

    更新日期:2013-10-10 00:00:00

  • Effect of nigrostriatal damage induced by 6-hydroxydopamine on the expression of glial cell line-derived neurotrophic factor in the striatum of the rat.

    abstract::Several types of brain injuries have been associated with alterations in the striatal expression of neurotrophic factors, including glial cell line-derived neurotrophic factor (GDNF). However, contradictory results on the striatal expression of GDNF have been reported in different animal models of Parkinson's disease....

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2009.04.036

    authors: Mertens B,Massie A,Michotte Y,Sarre S

    更新日期:2009-08-04 00:00:00

  • Steroid hormones protect spinal cord neurons from glutamate toxicity.

    abstract::The effects of steroid hormones on glutamate neurotoxicity were examined in cultured spinal cord neurons. The extent of neuronal damage, produced by glutamate exposure for 15 min, was estimated based on the activity of lactate dehydrogenase released from degenerated neurons to the media during 24 h of post-exposure in...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(93)90513-f

    authors: Ogata T,Nakamura Y,Tsuji K,Shibata T,Kataoka K

    更新日期:1993-07-01 00:00:00

  • OSO paradigm--A rapid behavioral screening method for acute psychosocial stress reactivity in mice.

    abstract::Chronic psychosocial stress is an important environmental risk factor for the development of psychiatric diseases. However, studying the impact of chronic psychosocial stress in mice is time consuming and thus not optimally suited to 'screen' increasing numbers of genetically manipulated mouse models for psychiatric e...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2015.11.043

    authors: Brzózka MM,Unterbarnscheidt T,Schwab MH,Rossner MJ

    更新日期:2016-02-09 00:00:00

  • Axonal transport of 16S acetylcholinesterase is increased in regenerating peripheral nerve in guinea-pig, but not in rat.

    abstract::The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(88)90365-x

    authors: Engel AK,Tetzlaff W,Kreutzberg GW

    更新日期:1988-02-01 00:00:00

  • Lysophosphatidic acid stimulates calcium transients in enteric glia.

    abstract::The enteric nervous system plays an integral role in the gastrointestinal tract. Within this intricate network, enteric glia are crucial in the maintenance of normal bowel function, yet their signaling mechanisms are poorly understood. Enteric glia, and not enteric neurons, selectively responded to lysophosphatidic ac...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2003.10.003

    authors: Segura BJ,Zhang W,Cowles RA,Xiao L,Lin TR,Logsdon C,Mulholland MW

    更新日期:2004-01-01 00:00:00

  • Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats.

    abstract::Isoflurane preconditioning improved short-term neurological outcome after focal brain ischemia in adult rats. It is not known whether desflurane induces a delayed phase of preconditioning in the brain and whether isoflurane preconditioning-induced neuroprotection is long-lasting. Two months-old Sprague-Dawley male rat...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2009.08.011

    authors: Li L,Zuo Z

    更新日期:2009-12-01 00:00:00

  • Aggressive experience increases dendritic spine density within the nucleus accumbens core in female Syrian hamsters.

    abstract::Activity within the mesolimbic dopamine system is associated with the performance of naturally motivated behaviors, one of which is aggression. In male rats, aggressive behavior induces neurochemical changes within the nucleus accumbens, a key structure within the mesolimbic dopamine system. Corresponding studies have...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2012.09.064

    authors: Staffend NA,Meisel RL

    更新日期:2012-12-27 00:00:00

  • Probucol inhibits neural cell apoptosis via inhibition of mTOR signaling pathway after spinal cord injury.

    abstract::Autophagy plays an essential role in neurodevelopment, axonal guidance, neuropathic pain remission, and neuronal survival. Inhibiting the mammalian target of rapamycin (mTOR) signaling pathway can induce the occurrence of autophagy. In this study, we initially detected the effect of probucol on autophagy after spinal ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2016.05.019

    authors: Zhou Z,Chen S,Zhao H,Wang C,Gao K,Guo Y,Shen Z,Wang Y,Wang H,Mei X

    更新日期:2016-08-04 00:00:00

  • Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors.

    abstract::This study has investigated the role of hypothalamic and amygdalar type-1 cannabinoid (CB1) receptors in the emotional and neuroendocrine responses to stress. To do so, we used the Cre/loxP system to generate conditional mutant mice lacking the CB1 gene in neurons expressing the transcription factor single-minded 1 (S...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2011.08.049

    authors: Dubreucq S,Kambire S,Conforzi M,Metna-Laurent M,Cannich A,Soria-Gomez E,Richard E,Marsicano G,Chaouloff F

    更新日期:2012-03-01 00:00:00

  • Blockade of brain histamine metabolism alters methamphetamine-induced expression pattern of stereotypy in mice via histamine H1 receptors.

    abstract::The administration of methamphetamine (METH, 10 mg/kg, i.p.) to male ICR mice induced stereotyped behavior consisting of nail and/or wood chip biting (86.0%), continuous sniffing (12.0%), head bobbing (1.1%), and circling (1.0%) during the observation period of 1 h. Pretreatment of the mice with metoprine (2, 10, and ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2007.05.006

    authors: Kitanaka J,Kitanaka N,Tatsuta T,Morita Y,Takemura M

    更新日期:2007-07-13 00:00:00

  • Inflammation modulates the contribution of receptor-subtypes to bradykinin-induced hyperalgesia in the rat.

    abstract::While B2 receptors mediate pain and hyperalgesia induced by bradykinin, in normal rats, recent reports indicate that, in the setting of inflammation, B1 receptors also mediate pain and hyperalgesia. Since bradykinin-induced hyperalgesia in normal rats is mediated by prostaglandins released from the postganglionic symp...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(95)00280-v

    authors: Khasar SG,Miao FJ,Levine JD

    更新日期:1995-11-01 00:00:00

  • Histogenesis at the level of the basal forebrain: the entopeduncular nucleus.

    abstract::This study shows that the neurons of the entopeduncular nucleus are derived from a longitudinal slab of isochronically generated neurons on day 11 and 15 h of gestation. Many neurons of this longitudinal slab which we have named the basal forebrain cell column, originate from an ependymal matrix closely associated wit...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(86)90032-1

    authors: Marchand R,Lajoie L,Blanchet C

    更新日期:1986-03-01 00:00:00

  • Dendritic arborization and axon trajectory of neurons in the hypothalamic arcuate nucleus of the rat--updated.

    abstract::Neurons in the hypothalamic arcuate nucleus (arcuate neurons) were traced on Golgi-impregnated sections. Dendrites of arcuate neurons showed characteristic orientation patterns. Dendrites along the lateral side follow the convex border of the nucleus by running parallel to the tanycyte processes. Neurons located in th...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(85)90005-3

    authors: Réthelyi M

    更新日期:1985-10-01 00:00:00

  • Localization of dynorphin gene product-immunoreactivity in neurons from spinal cord and dorsal root ganglia.

    abstract::Using spinal cord and dorsal root ganglion cell cultures, we have studied the immuno-histochemical distribution of several peptide products of the dynorphin gene. With antibody directed toward the midregion of dynorphin A, peptide-immunoreactivity was found exclusively in the cell bodies of spinal cord neurons. Antibo...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(86)90110-7

    authors: Sweetnam PM,Wrathall JR,Neale JH

    更新日期:1986-08-01 00:00:00

  • Distribution of Fos-immunoreactive cells in rat forebrain and midbrain following social defeat stress and diazepam treatment.

    abstract::The anxiolytic diazepam selectively inhibits psychological stress-induced autonomic and behavioral responses without causing noticeable suppression of other central performances. This pharmacological property of diazepam led us to the idea that neurons that exhibit diazepam-sensitive, psychological stress-induced acti...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2014.04.047

    authors: Lkhagvasuren B,Oka T,Nakamura Y,Hayashi H,Sudo N,Nakamura K

    更新日期:2014-07-11 00:00:00

  • Histamine and corticosterone modulate Acid sensing ion channels (ASICs) dependent long-term potentiation at the mouse anterior cingulate cortex.

    abstract::Increase in proton concentration [H+] or decrease in local and global extracellular pH occurs in both physiological and pathological conditions. Acid-sensing ion channels (ASICs), belonging to the ENaC/Deg superfamily, play an important role in signal transduction as proton sensor. ASICs and in particular ASIC-1a (one...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2021.01.022

    authors: Natalia Gobetto M,González-Inchauspe Osvaldo D Uchitel C

    更新日期:2021-01-22 00:00:00

  • Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.

    abstract::Neurosteroids such as dehydroepiandrosterone (DHEA), pregnenolone and 17beta-estradiol are synthesized by cytochrome P450s from endogenous cholesterol. We previously reported a new cytochrome P450 enzyme, CYP7B, highly expressed in rat and mouse brain that metabolizes DHEA and related steroids by hydroxylation at the ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(03)00438-x

    authors: Yau JL,Rasmuson S,Andrew R,Graham M,Noble J,Olsson T,Fuchs E,Lathe R,Seckl JR

    更新日期:2003-01-01 00:00:00