Distribution of neurotensin binding sites in the caudal brainstem of the rat: a light microscopic radioautographic study.

abstract：:Hippocampal neurogenesis and associated cognitive behaviors are regulated by a number of factors including stress, inflammation, and exercise. However, the interplay between these factors remains relatively unexplored, especially across the lifespan. In the current study, the effect of social isolation stress during t...

journal_title：Neuroscience

authors： Hueston CM,Cryan JF,Nolan YM

更新日期：2017-12-04 00:00:00

abstract：:Neurobiological and genetic mechanisms underlying increased intake of and preference for nutritive sugars over non-nutritive sweeteners are not fully understood. We examined the roles of subnuclei of the amygdala in the shift in preference for a nutritive sugar. Food-deprived mice alternately received caloric sucrose ...

journal_title：Neuroscience

authors： Yasoshima Y,Yoshizawa H,Shimura T,Miyamoto T

更新日期：2015-04-16 00:00:00

abstract：:The mechanisms underlying antiepileptic or antiepileptogenic effects of repeated transcranial magnetic stimulation (rTMS) are poorly understood. In this study, we investigated the effect of rTMS applied during rapid amygdala kindling on some electrophysiological properties of hippocampal CA1 pyramidal neurons. Male Wi...

journal_title：Neuroscience

authors： Shojaei A,Semnanian S,Janahmadi M,Moradi-Chameh H,Firoozabadi SM,Mirnajafi-Zadeh J

更新日期：2014-11-07 00:00:00

abstract：:A recent series of studies in rats has demonstrated positively reinforcing and memory enhancing effects following lesions of the nucleus tuberomammillaris, which is the only known source of neuronal histamine. The aim of the present experiments was to assess whether inhibition of histaminergic neurotransmission in the...

journal_title：Neuroscience

authors： Zimmermann P,Privou C,Huston JP

更新日期：1999-01-01 00:00:00

abstract：:Neuroinflammation is associated with increased vulnerability to diverse psychiatric conditions, including treatment-resistant major depressive disorder (MDD). Here we assessed whether high fat diet (HFD) induced neuroinflammation may be suitable to model a treatment-resistant depressive-like brain state in mice. Male ...

journal_title：Neuroscience

authors： Feng M,Crowley NA,Patel A,Guo Y,Bugni SE,Luscher B

更新日期：2019-05-15 00:00:00

abstract：:Normal adult cerebellar Purkinje cells in the rat rarely express low-affinity nerve growth factor receptor immunoreactivity. However, intense anti-low-affinity nerve growth factor receptor immunostaining was observed as early as one day after a lesion of the cerebellar cortex. Low-affinity nerve growth factor receptor...

journal_title：Neuroscience

authors： Martínez-Murillo R,Caro L,Nieto-Sampedro M

更新日期：1993-02-01 00:00:00

abstract：:The GABAergic innervation of the extraocular motor nuclei in the cat was evaluated using postembedding immunocytochemical techniques. The characterization of GABA-immunoreactive terminals in the oculomotor nucleus was carried out at the light and electron microscopic levels. GABA-immunopositive puncta suggestive of bo...

journal_title：Neuroscience

authors： de la Cruz RR,Pastor AM,Martínez-Guijarro FJ,López-García C,Delgado-García JM

更新日期：1992-12-01 00:00:00

abstract：:Electrophysiological records of unit activity were used to compare the effects of excitotoxic pallidal lesions and 6-hydroxydopamine-induced damage to the midbrain dopaminergic neurons on the discharge rates and patterns of the subthalamic neurons. Removal of the pallidal input induced a slight, but statistically sign...

journal_title：Neuroscience

authors： Hassani OK,Mouroux M,Féger J

更新日期：1996-05-01 00:00:00

abstract：:In vitro receptor autoradiography was used to localize, quantify and characterize [125I-Tyr8]bradykinin binding sites in all major spinal cord segments of normal rats and animals subjected to various chemical treatments and surgical lesions. [125I-Tyr8]bradykinin specific binding sites were predominantly located to su...

journal_title：Neuroscience

authors： Lopes P,Kar S,Chrétien L,Regoli D,Quirion R,Couture R

更新日期：1995-10-01 00:00:00

abstract：:Undifferentiated PC12 cells undergo apoptosis, via a calcium-induced calcium release mechanism, when the calcium-binding protein purified from bovine brain (native S100) is present in micromolar concentration in the medium. This process begins when S100 binds to specific membrane binding sites and involves up to 50% o...

journal_title：Neuroscience

authors： Fulle S,Mariggiò MA,Belia S,Petrelli C,Ballarini P,Guarnieri S,Fanò G

更新日期：1999-03-01 00:00:00

abstract：:The effects of muscle fatigue are known to be altered in older adults, and age-related changes in the brain are likely to be a contributing factor. However, the neural mechanisms underlying these changes are not known. The aim of the current study was to use transcranial magnetic stimulation combined with electroencep...

journal_title：Neuroscience

authors： Opie GM,Otieno LA,Pourmajidian M,Semmler JG,Sidhu SK

更新日期：2020-01-15 00:00:00

abstract：:Neonatal posterior cingulate cortex lesions spare the spatial deficits that characterize adult lesions. The present experiments examined the possibility that the anterior cingulate cortex mediates the spared spatial behavior. Rats were given bilateral lesions of the posterior cingulate cortex or anterior plus posterio...

journal_title：Neuroscience

authors： Gonzalez CL,Whishaw IQ,Kolb B

更新日期：2003-01-01 00:00:00

abstract：:Neurotrophic factors are known to promote neuronal survival during development and after acute brain injury. Recent data suggest that some neuropeptides also exhibit neurotrophic activities, as shown for the pituitary adenylate cyclase activating polypeptide, which increases the survival of various neuronal population...

journal_title：Neuroscience

authors： Skoglösa Y,Lewén A,Takei N,Hillered L,Lindholm D

更新日期：1999-04-01 00:00:00

abstract：:We have reported that hypoxia affects the hypothalamic-pituitary-adrenal (HPA) axis and behavior by driving the expression of central corticotropin-releasing hormone (CRH) and its receptors in adult mammals, and this effect is modulated by other factors. Here, we address whether or not intermittent hypoxia (IH) or res...

journal_title：Neuroscience

authors： Fan JM,Chen XQ,Jin H,Du JZ

更新日期：2009-04-10 00:00:00

abstract：:Progesterone (PROG) shows neuroprotective effects in numerous lesion models, including a mouse model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). However, the possible beneficial effects of PROG on the behavioral and neurochemical impairments incurred in the hemiparkinson...

journal_title：Neuroscience

authors： Chao OY,Huston JP,von Bothmer A,Pum ME

更新日期：2011-11-24 00:00:00

abstract：:Oxytocin and vasopressin binding sites were localized and characterized by quantitative autoradiography on consecutive sections of Long-Evans rat forebrains and pituitary glands, incubated in the presence of 5 nM [3H]oxytocin or 5 nM [3H]vasopressin. In the forebrain, two types of neurohypophysial hormone binding site...

journal_title：Neuroscience

authors： Freund-Mercier MJ,Stoeckel ME,Dietl MM,Palacios JM,Richard P

更新日期：1988-07-01 00:00:00

abstract：:The neuropeptides somatostatin, neurotensin and substance P were investigated in rats during and after limbic seizures induced by systemic injection of kainic acid (10 mg/kg, i.p.). Three hours after injection of the toxin, pronounced decreases (40-50%) in somatostatin-like immunoreactivity in frontal cortex, striatum...

journal_title：Neuroscience

authors： Sperk G,Wieser R,Widmann R,Singer EA

更新日期：1986-04-01 00:00:00

abstract：:Mesial temporal lobe epilepsy (MTLE) is often characterized pathologically by severe neuronal loss in the hippocampus. In this study we investigated concomitant appearance of the pro-apoptotic and anti-apoptotic mechanisms in injured neurons in epileptic human hippocampi. Postsurgical hippocampal specimens of randomly...

journal_title：Neuroscience

authors： Dericioglu N,Soylemezoglu F,Gursoy-Ozdemir Y,Akalan N,Saygi S,Dalkara T

更新日期：2013-05-01 00:00:00

abstract：:Administration of kainic acid induces acute seizures that result in the loss of neurons, gliosis and reorganization of mossy fiber pathways in the hippocampus resembling those observed in human temporal lobe epilepsy. Although these structural changes have been well characterized, the mechanisms underlying the degener...

journal_title：Neuroscience

authors： Banerjee M,Sasse VA,Wang Y,Maulik M,Kar S

更新日期：2015-01-22 00:00:00

abstract：:The uncrossed retinotectal projection of rats undergoes extensive axonal elimination and subsequent growth of axonal arbors in topographically appropriate territories within the first two/three postnatal weeks. Nitric oxide has been implicated in development and stabilization of synapses in the retinotectal pathway si...

journal_title：Neuroscience

authors： Campello-Costa P,Fosse-Júnior AM,Oliveira-Silva P,Serfaty CA

更新日期：2006-01-01 00:00:00

abstract：:Estrogen exerts many of its receptor-mediated neuroprotective functions through the activation of various intracellular signal transduction pathways including the mitogen activating protein kinase (MAPK), phospho inositol-3 kinase and protein kinase C pathways. Here we have used a hippocampal slice culture model of ka...

journal_title：Neuroscience

authors： Goodenough S,Schleusner D,Pietrzik C,Skutella T,Behl C

更新日期：2005-01-01 00:00:00

abstract：:Amphetamine induces a pronounced rotation directed ipsilateral to the lesion and lasting about 2 h in rats bearing a unilateral lesion of the nigrostriatal dopaminergic pathway. Implantation of embryonic dopaminergic neurons into the lesioned striatum leads to a compensation of this rotation. However, graft-bearing an...

journal_title：Neuroscience

authors： Herman JP,Rouge-Pont F,Le Moal M,Abrous DN

更新日期：1993-04-01 00:00:00

abstract：:Formalin (10%) induces higher levels of licking and flexing in female than in male rats, as shown in the present study. In order to ascertain the neural and hormonal modifications that accompany these behavioural differences, we determined the activity of choline acetyltransferase in the hippocampus and the levels of ...

journal_title：Neuroscience

authors： Aloisi AM,Albonetti ME,Carli G

更新日期：1996-10-01 00:00:00

abstract：:In brainstem motor networks, hypoglossal motoneurons (HMs) play the physiological role of driving tongue contraction, an activity critical for inspiration, phonation, chewing and swallowing. HMs are an early target of neurodegenerative diseases like amyotrophic lateral sclerosis that, in its bulbar form, is manifested...

journal_title：Neuroscience

authors： Ghezzi F,Monni L,Corsini S,Rauti R,Nistri A

更新日期：2017-12-26 00:00:00

abstract：:Previous research has implicated hippocampal rhythmical slow activity in the mechanisms of action of the anxiolytic drugs. In this study ethanol and a putative ethanol antagonist, Ro 15-4513, were investigated with reticular elicitation of rhythmical slow activity. Doses of ethanol between 0.6 and 3.1 g/kg were used. ...

journal_title：Neuroscience

authors： Coop CF,McNaughton N,Warnock K,Laverty R

更新日期：1990-01-01 00:00:00

abstract：:In cultured bovine adrenal medullary cells, neosurugatoxin and histrionicotoxin inhibited carbachol-induced influx of 22Na, 45Ca and secretion of catecholamines with IC50 of 27 nM and 3 microM, respectively. The inhibitory effects of neosurugatoxin were reversed by the increased concentrations of carbachol, whereas th...

journal_title：Neuroscience

authors： Wada A,Uezono Y,Arita M,Tsuji K,Yanagihara N,Kobayashi H,Izumi F

更新日期：1989-01-01 00:00:00

abstract：:The rapid eye movement dreaming sleep stage and schizophrenia are both characterized by common intracerebral disconnections, disturbed responsiveness and sensory deafferentation processes. Moreover, in both states, there is dorsolateral prefrontal deactivation as shown by the decrease of blood flow. Finally, identical...

journal_title：Neuroscience

authors： Gottesmann C

更新日期：2006-07-21 00:00:00

abstract：:The effects of steady iontophoretic applications of serotonin on the spontaneous discharge and on the excitatory responses induced in deep cerebellar nuclei neurons by iontophoretic pulse applications of L-glutamate, L-aspartate, N-methyl-D,L-aspartate and quisqualate were studied in rat cerebellar slices maintained i...

journal_title：Neuroscience

authors： Gardette R,Krupa M,Crepel F

更新日期：1987-11-01 00:00:00

abstract：:Studies show that maternal consumption of a high-fat diet (HFD) can impair the formation of hypothalamic neuronal circuits in mouse offspring. This damage can be mediated by Notch1/Hes5 signaling activation, leading to repression of proneural factors such as Mash1 and Ngn2/3, which are essential for neuronal different...

journal_title：Neuroscience

authors： Lemes SF,de Souza ACP,Payolla TB,Versutti MD,de Fátima da Silva Ramalho A,Mendes-da-Silva C,Souza CM,Milanski M,Torsoni AS,Torsoni MA

更新日期：2018-02-10 00:00:00

abstract：:Nerve growth factor (NGF) synthesized in peripheral organs plays a critical role in the development and maintenance of the nervous system and also participates in processing nociceptive stimuli. Previous studies suggest that reproductive hormones may regulate the expression of NGF. Ovariectomies were performed on fema...

journal_title：Neuroscience

authors： Bjorling DE,Beckman M,Clayton MK,Wang ZY

更新日期：2002-01-01 00:00:00