The dreaming sleep stage: a new neurobiological model of schizophrenia?

abstract：:The motor output of hypoglossal motoneurons to tongue muscles takes place in concert with the respiratory rhythm and is determined by the balance between excitatory glutamatergic transmission and inhibitory transmission mediated by glycine or GABA. The relative contribution by these transmitters is a phasic phenomenon...

journal_title：Neuroscience

authors： Pagnotta SE,Lape R,Quitadamo C,Nistri A

更新日期：2005-01-01 00:00:00

abstract：:Using in vitro autoradiography, we investigated [3H] alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate, [3H]kainate and [3H]N-methyl-D-aspartate binding in two forebrain regions, the hippocampus and striatum, of young (four months of age) and aged (24-25 months of age) Long-Evans rats that had previously been teste...

journal_title：Neuroscience

authors： Nicolle MM,Bizon JL,Gallagher M

更新日期：1996-10-01 00:00:00

abstract：:In rodents, reproductively relevant pheromonal cues are detected by receptors in the vomeronasal organ, which in turn transmit this information centrally via the accessory olfactory bulb, the medial nucleus of the amygdala, the posterior medial bed nucleus of the stria terminalis and the medial preoptic area. In the r...

journal_title：Neuroscience

authors： Bressler SC,Baum MJ

更新日期：1996-04-01 00:00:00

abstract：:The spinal cord is innervated by brainstem serotonergic neurons, some of which contain substance P and/or thyrotropin-releasing hormone in addition to serotonin. These neurons project at least three types of axons to the spinal cord: those containing both substance P and thyrotropin-releasing hormone, those containing...

journal_title：Neuroscience

authors： Wu W,Elde R,Wessendorf MW

更新日期：1993-07-01 00:00:00

abstract：:The schizophrenia-susceptibility gene, dystrobrevin-binding protein 1 (DTNBP1), encodes the dysbindin protein and mediates neurotransmission and neurodevelopment in normal subjects. Functional studies show that DTNBP1 loss may cause deficient presynaptic vesicle transmission, which is related to multiple psychiatric d...

journal_title：Neuroscience

authors： Hu H,Wang X,Li C,Li Y,Hao J,Zhou Y,Yang X,Chen P,Shen X,Zhang S

更新日期：2021-01-01 00:00:00

abstract：:Localized distension of the intestine evokes an ascending excitatory reflex and a descending inhibitory reflex in the circular muscle layer. The sequential activation of these two reflexes is believed to underlie the motor pattern of peristalsis, which is responsible for the co-ordinated propulsion of intestinal conte...

journal_title：Neuroscience

authors： Tonini M,Costa M,Brookes SJ,Humphreys CM

更新日期：1996-07-01 00:00:00

abstract：:This study examined the age-related subsequent memory effect (SME) in perceptual and semantic encoding using event-related potentials (ERPs). Seventeen younger adults and 17 older adults studied a series of Chinese characters either perceptually (by inspecting orthographic components) or semantically (by determining w...

journal_title：Neuroscience

authors： Kuo MC,Liu KP,Ting KH,Chan CC

更新日期：2014-03-07 00:00:00

abstract：:In the past 15 years the classical view that astrocytes play a relatively passive role in brain function has been overturned and it has become increasingly clear that signaling between neurons and astrocytes may play a crucial role in the information processing that the brain carries out. This new view stems from two ...

journal_title：Neuroscience

authors： Santello M,Volterra A

更新日期：2009-01-12 00:00:00

abstract：:The rat neurohypophysis contains a population of microglial cells, the majority of which occupy a pericapillary position in the resting gland. The microglia are immunocytochemically identifiable by the presence of macrophage-associated antigens and resemble microglia of the CNS. Morphometry at light and electron micro...

journal_title：Neuroscience

authors： Pow DV,Perry VH,Morris JF,Gordon S

更新日期：1989-01-01 00:00:00

abstract：:Nucleotide-activated P2X channels and P2Y metabotropic receptors participate in nociceptive signaling. Agonist availability is regulated by nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), -2, -3, and -8, a family of enzymes that hydrolyze extracellular ATP to generate ADP (a P2Y agonist) and AMP. They provide...

journal_title：Neuroscience

authors： Vongtau HO,Lavoie EG,Sévigny J,Molliver DC

更新日期：2011-10-13 00:00:00

abstract：:We have raised antisera against the GABA analogues gamma-vinyl GABA, diaminobutyric acid and gabaculine. These analogues are thought to be substrates for high-affinity GABA transporters. Retinae were exposed to micromolar concentrations of these analogues in the presence or absence of uptake inhibitors and then fixed ...

journal_title：Neuroscience

authors： Pow DV,Baldridge W,Crook DK

更新日期：1996-08-01 00:00:00

abstract：:It has recently become clear that the neurotrophic factor, nerve growth factor, interacts specifically with nociceptive sensory neurons during development and maturity. Indeed, it may serve as a critical link between inflammation and the hyperalgesia that ensues in adult animals. Nerve growth factor is normally expres...

journal_title：Neuroscience

authors： Davis BM,Lewin GR,Mendell LM,Jones ME,Albers KM

更新日期：1993-10-01 00:00:00

abstract：:Repeated exposure to cocaine during sensitive periods of forebrain development produces specific, long-lasting changes in the structure and function of maturing neural circuits. Similar regimens of drug exposure in adult animals with mature, homeostatically regulated nervous systems produce neuroadaptations that appea...

journal_title：Neuroscience

authors： Stanwood GD,Levitt P

更新日期：2003-01-01 00:00:00

abstract：:A transient aberrant projection from the retina to the contralateral inferior colliculus was demonstrated in pigmented rats in both whole-brains and sections following intra-ocular injection of horseradish peroxidase. The projection was prominent on the day of birth but reached its maximum density and extent after inj...

journal_title：Neuroscience

authors： Cooper AM,Cowey A

更新日期：1990-01-01 00:00:00

abstract：:Three closely-linked clusters of protocadherin (Pcdh) genes (alpha, beta, and gamma) encoding more than 50 distinct mRNAs have been identified in humans and mice, and proposed to play important roles in neuronal connectivity in the CNS. The human and mouse Pcdh alpha and gamma clusters each span a region of about 300 ...

journal_title：Neuroscience

authors： Zou C,Huang W,Ying G,Wu Q

更新日期：2007-01-19 00:00:00

abstract：:The cellular localization of preprosomatostatin mRNA in the rat brain and sensory ganglia has been examined in detail using a newly developed highly sensitive non-radioactive in situ hybridization histochemistry procedure. An alkaline phosphatase labelled anti-sense 30mer oligodeoxynucleotide probe was used for detect...

journal_title：Neuroscience

authors： Kiyama H,Emson PC

更新日期：1990-01-01 00:00:00

abstract：:The hippocampus maintains the remarkable ability to generate new neurons throughout the lifespan. Progenitor cells in the subgranular zone give rise mainly to granule cells that migrate to the granule cell layer and become mature, functionally integrated neurons. Numerous factors are capable of regulating the prolifer...

journal_title：Neuroscience

authors： Spanswick SC,Epp JR,Sutherland RJ

更新日期：2011-09-08 00:00:00

abstract：:We investigated computer models of a single thalamocortical neuron to assess the interaction of intrinsic voltage-sensitive channels and cortical synaptic input in producing the range of oscillation frequencies observed in these cells in vivo. A morphologically detailed model with Hodgkin-Huxley-like ion channels demo...

journal_title：Neuroscience

authors： Lytton WW,Destexhe A,Sejnowski TJ

更新日期：1996-02-01 00:00:00

abstract：:Long-lasting neuroadaptations that occur during drug use and remain after withdrawal are thought to contribute to the persisting and compulsive nature of drug addiction and relapse. At the molecular and cellular levels, mechanisms that have been implicated in the normal process of memory formation are increasingly bei...

journal_title：Neuroscience

authors： Thompson AM,Swant J,Gosnell BA,Wagner JJ

更新日期：2004-01-01 00:00:00

abstract：:Melanin-concentrating hormone (MCH) is a hypothalamic neuropeptide that has been implicated in energy homeostasis. Pharmacological studies with MCH and its receptor antagonists have suggested additional behavioral roles for the neuropeptide in the control of mood and vigilance states. These suggestions have been suppo...

journal_title：Neuroscience

authors： Willie JT,Sinton CM,Maratos-Flier E,Yanagisawa M

更新日期：2008-10-28 00:00:00

abstract：:The involvement of nitric oxide in neurodegenerative processes still remains incompletely characterized. Although nitric oxide has been reported to be an important mediator in neuronal degeneration in different models of cell death involving NMDA-receptor activation, increasing evidence for protective mechanisms has b...

journal_title：Neuroscience

authors： Lautenschlager M,Onufriev MV,Gulyaeva NV,Harms C,Freyer D,Sehmsdorf U,Ruscher K,Moiseeva YV,Arnswald A,Victorov I,Dirnagl U,Weber JR,Hörtnagl H

更新日期：2000-01-01 00:00:00

abstract：:Multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), are crucially dependent on the invasion of activated autoreactive lymphocytes and blood macrophages into the central nervous system (CNS). Proinflammatory mononuclear cells and activated local microglia mediate inflammation, demy...

journal_title：Neuroscience

authors： Bibolini MJ,Scerbo MJ,Roth GA,Monferran CG

更新日期：2014-09-26 00:00:00

abstract：:Although there are clear interactions between circadian rhythms and drug addiction, mechanisms for such interactions remain unknown. Studies have shown that the circadian clock gene Period in Drosophila melanogaster could influence behavioral responses to cocaine, and the mouse homologues, mPer1 and mPer2, modulate co...

journal_title：Neuroscience

authors： Liu Y,Wang Y,Jiang Z,Wan C,Zhou W,Wang Z

更新日期：2007-04-25 00:00:00

abstract：:The effect of intracranial microdialysis on brain glucose metabolism in control and kainic acid-treated rats was assessed by semi-quantitative [14C]2-deoxyglucose autoradiography. A dialysis fiber loop was implanted into the piriform cortex or a horizontal Vita fiber into the hippocampus, and 24 h later, fibers were p...

journal_title：Neuroscience

authors： Chastain JE Jr,Samson F,Nelson SR,Pazdernik TL

更新日期：1990-01-01 00:00:00

abstract：:Alternative splicing is an important mechanism for expanding proteome diversity from a limited number of genes, especially in higher vertebrates. Brain-specific splicing factors play an important role in establishing specific patterns of alternative splicing in the brain and thereby contribute to its complex architect...

journal_title：Neuroscience

authors： Jelen N,Ule J,Zivin M

更新日期：2010-08-25 00:00:00

abstract：:There is increasing evidence indicating that estrogen replacement therapy produces neuroprotective actions but has undesirable side effects on the reproductive system. Raloxifene is a selective estrogen receptor modulator that exerts estrogen agonist action in the brain while acting as an estrogen antagonist in the re...

journal_title：Neuroscience

authors： Huang Y,Huang YL,Lai B,Zheng P,Zhu YC,Yao T

更新日期：2007-06-29 00:00:00

abstract：:During the early developmental period, long-term potentiation (LTP) can be induced in both vertical and horizontal connections in the rat visual cortex. However, the temporal difference in LTP change between the two pathways during animal development remains unclear. In this study, LTP in vertical (from layer IV to la...

journal_title：Neuroscience

authors： Li DK,Zhang C,Gu Y,Zhang SH,Shi J,Chen XH

更新日期：2017-05-14 00:00:00

abstract：:The neuropeptides somatostatin, neurotensin and substance P were investigated in rats during and after limbic seizures induced by systemic injection of kainic acid (10 mg/kg, i.p.). Three hours after injection of the toxin, pronounced decreases (40-50%) in somatostatin-like immunoreactivity in frontal cortex, striatum...

journal_title：Neuroscience

authors： Sperk G,Wieser R,Widmann R,Singer EA

更新日期：1986-04-01 00:00:00

abstract：:While systemic capsaicin in adult rats is known to reduce substance P and somatostatin in primary sensory nerves, it is still unknown if it also affects the production of these peptides at the genetic level. Therefore, we examined the effects of systemically administered capsaicin on the expression of the beta-preprot...

journal_title：Neuroscience

authors： Kashiba H,Ueda Y,Senba E

更新日期：1997-01-01 00:00:00

abstract：:The distributions of the alpha 1-adrenoceptor and its subtypes (alpha 1A and alpha 1B) in human and rat hippocampus are analysed by quantitative receptor autoradiography. alpha 1-Adrenoceptors are labelled by [3H]prazosin. The alpha 1A subtype is visualized by [3H]prazosin after irreversible blockade of alpha 1B adren...

journal_title：Neuroscience

authors： Zilles K,Gross G,Schleicher A,Schildgen S,Bauer A,Bahro M,Schwendemann G,Zech K,Kolassa N

更新日期：1991-01-01 00:00:00