Raloxifene acutely reduces glutamate-induced intracellular calcium increase in cultured rat cortical neurons via inhibition of high-voltage-activated calcium current.

abstract：:Interactions of acoustic and somatosensory evoked potentials were studied in the anterior suprasylvian gyrus of the cat. Two kinds of interaction could be observed: occlusion or facilitation. In most cases occlusion was observed. The interactions showed dynamic changes and were susceptible to different kinds of influe...

journal_title：Neuroscience

authors： Toldi J,Fehér O,Feuer L

更新日期：1984-11-01 00:00:00

abstract：:Sigma receptor (sigmaR), known as a unique nonopiate, nonphencyclidine brain receptor, can bind diverse classes of psychotropic drugs, neurosteroids and other synthetic compounds, such as (+)pentazocine, etc. Two types of sigmaRs have been identified: sigmaR1 and sigmaR2. In this work, we examined the expression of si...

journal_title：Neuroscience

authors： Liu LL,Wang L,Zhong YM,Yang XL

更新日期：2010-06-02 00:00:00

abstract：:The mechanical response of human m. flexor pollicis longus to slow (3.2 degrees/s) linear stretch by 5.5 degrees was measured during sustained (45-60 s, 9-13.5 p.p.s.) unfused tetanus evoked by electrical stimulation. The stiffness increased during unfused tetanus. At the late phase of unfused tetanus it was 1.8 +/- 0...

journal_title：Neuroscience

authors： Gurfinkel VS,Ivanenko YP,Levik YS

更新日期：1997-09-01 00:00:00

abstract：:Relay cells of dorsal lateral geniculate nucleus (LGN) receive a Class 1 glutamatergic input from the retina and a Class 2 input from cortical layer 6. Among the properties of Class 2 synapses is the ability to activate metabotropic glutamate receptors (mGluRs), and mGluR activation is known to affect thalamocortical ...

journal_title：Neuroscience

authors： Lam YW,Sherman SM

更新日期：2013-07-09 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPARγ) belongs to a family of ligand-activated transcription factors, and its ligands are known to control many physiological and pathological conditions. The hypothesis of our study was that the PPARγ agonist (rosiglitazone) could mediate tumor necrosis factor alpha (...

journal_title：Neuroscience

authors： Chiang MC,Cheng YC,Lin KH,Yen CH

更新日期：2013-01-15 00:00:00

abstract：:The effects of intense noise exposure on the classical auditory pathway have been extensively investigated; however, little is known about the effects of noise-induced hearing loss on non-classical auditory areas in the brain such as the lateral amygdala (LA) and striatum (Str). To address this issue, we compared the ...

journal_title：Neuroscience

authors： Chen GD,Sheppard A,Salvi R

更新日期：2016-02-19 00:00:00

abstract：:Activation of muscarinic receptors leads to proliferation of astroglial cells and this effect is inhibited by ethanol. Among the intracellular pathways involved in the mitogenic action of muscarinic agonists, activation of the atypical protein kinase C zeta (PKC zeta) appears to be of most importance, and is also affe...

journal_title：Neuroscience

authors： Guizzetti M,Bordi F,Dieguez-Acuña FJ,Vitalone A,Madia F,Woods JS,Costa LG

更新日期：2003-01-01 00:00:00

abstract：:During regeneration of injured peripheral nerves, local conditions may influence how regenerative axon sprouts emerge from parent axons. More extensive lesions might be expected to disrupt such growth. In this work, we discovered instead that long segmental crush injuries facilitate the growth and maturation of substa...

journal_title：Neuroscience

authors： Xu QG,Midha R,Martinez JA,Guo GF,Zochodne DW

更新日期：2008-04-09 00:00:00

abstract：:Recent studies have shown that tachykinins mediate slow synaptic transmission to myenteric AH (afterhyperpolarising) neurons via neurokinin-3 receptors (NK(3)R). This study investigated a similar role for neurokinin-1 receptors (NK(1)R) and compared the effect of selective receptor antagonists on non-cholinergic slow ...

journal_title：Neuroscience

authors： Johnson PJ,Bornstein JC

更新日期：2004-01-01 00:00:00

abstract：:The N-methyl-D-aspartate receptor antagonist 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid and the non-N-methyl-D-aspartate receptor antagonist, 6-cyano-7-nitroquinoxaline-2,3-dione have been iontophoretically applied to cells in the cat dorsal lateral geniculate nucleus and their effects on the visual re...

journal_title：Neuroscience

authors： Sillito AM,Murphy PC,Salt TE

更新日期：1990-01-01 00:00:00

abstract：:Dopamine in the prefrontal cortex plays a critical role in normal cognition throughout the lifespan and has been implicated in the pathophysiology of neuropsychiatric disorders such as schizophrenia and attention deficit disorder. Little is known, however, about the postnatal development of the dopaminergic system in ...

journal_title：Neuroscience

authors： Weickert CS,Webster MJ,Gondipalli P,Rothmond D,Fatula RJ,Herman MM,Kleinman JE,Akil M

更新日期：2007-02-09 00:00:00

abstract：:The results of a previous experiment suggest that the cell bodies of many jaw closing muscle spindle afferents in the trigeminal mesencephalic nucleus of the rabbit are phasically inhibited during fictive mastication. The aim of this study was to investigate one possible neurotransmitter system that could be involved ...

journal_title：Neuroscience

authors： Kolta A,Dubuc R,Lund JP

更新日期：1993-04-01 00:00:00

abstract：:The resting and reflex-evoked activities of single postganglionic sympathetic neurons with axons in the right thoracic vagus were tested in chloralose-anaesthetized cats. The properties of a majority of neurons were found to be similar. Cardiac- and inspiration-related rhythmicities were present in the resting activit...

journal_title：Neuroscience

authors： Bałkowiec A,Szulczyk P

更新日期：1992-01-01 00:00:00

abstract：:The subplate (SP) represents a transitory cytoarchitectural fetal compartment containing most subcortical and cortico-cortical afferents, and has a fundamental role in the structural development of the healthy adult brain. There is evidence that schizophrenia and autism may be determined by developmental defects in th...

journal_title：Neuroscience

authors： Serati M,Delvecchio G,Orsenigo G,Mandolini GM,Lazzaretti M,Scola E,Triulzi F,Brambilla P

更新日期：2019-06-01 00:00:00

abstract：:Dominant and subordinate males respond differently to the stress of social interaction. After an hour of social interaction, subordinate male Anolis carolinensis have elevated serotonergic activity in hippocampus, but dominant males do not. In other species, and using other stressors, the activation of hippocampal ser...

journal_title：Neuroscience

authors： Summers CH,Summers TR,Moore MC,Korzan WJ,Woodley SK,Ronan PJ,Höglund E,Watt MJ,Greenberg N

更新日期：2003-01-01 00:00:00

abstract：:Environmental enrichment of laboratory animals leads to multi-faceted changes to physiology, health and disease prognosis. An important and under-appreciated factor in enhancing cognition through environmental manipulation may be improved basic sensory function. Previous studies have highlighted changes in cortical se...

journal_title：Neuroscience

authors： Devonshire IM,Dommett EJ,Grandy TH,Halliday AC,Greenfield SA

更新日期：2010-10-13 00:00:00

abstract：:Arousal enhances the readiness to process sensory information and respond to it. Rapid increment of arousal, referred to as arousal reaction or startle, increases the level of attention and the chance of survival. Arousal reaction is known to originate from the brainstem ascending reticular activating system and to mo...

journal_title：Neuroscience

authors： Löfberg O,Julkunen P,Pääkkönen A,Karhu J

更新日期：2014-08-22 00:00:00

abstract：:According to the simulation theory, the internal simulation of a movement (imagined movement, IM) and its execution (actual movement, AM) are based on the same motor representations. The brain uses these representations for controlling action. The specific objective of this study was to investigate the updating proces...

journal_title：Neuroscience

authors： Chabeauti PY,Assaiante C,Vaugoyeau M

更新日期：2012-10-11 00:00:00

abstract：:Hotfoot is a mutant mouse with an ataxic phenotype which has been shown to be due to a mutation in the Grid2 gene. In this paper, we compare molecular, morphological, electrophysiological and behavioral features of two Grid2 alleles: Grid2(ho-4J) and Grid2(ho-Nancy). We first show that these two mutations are deletion...

journal_title：Neuroscience

authors： Lalouette A,Lohof A,Sotelo C,Guénet J,Mariani J

更新日期：2001-01-01 00:00:00

abstract：:The accessory olfactory bulb of the mouse was studied by current source-density analysis of field potentials to determine the laminar and temporal distribution of synaptic currents evoked by electrical stimulation of the vomeronasal organ. The one-dimensional current source-density analysis revealed two major spatiall...

journal_title：Neuroscience

authors： Kaba H,Keverne EB

更新日期：1992-07-01 00:00:00

abstract：:Accumulating evidence indicates that odontoblasts act as sensor cells, capable of triggering action potentials in adjacent pulpal nociceptive axons, suggesting a paracrine signaling via a currently unknown mediator. Since glutamate can mediate signaling by non-neuronal cells, and peripheral axons may express glutamate...

journal_title：Neuroscience

authors： Cho YS,Ryu CH,Won JH,Vang H,Oh SB,Ro JY,Bae YC

更新日期：2016-10-29 00:00:00

abstract：:In vitro cell cultures are an important tool for obtaining insights into cellular processes in an isolated system and a supplement to in vivo animal experiments. While primary dissociated cultures permit a single homogeneous cell population to be studied, there is a clear need to explore the function of brain cells in...

journal_title：Neuroscience

authors： Humpel C

更新日期：2015-10-01 00:00:00

abstract：:Cervical or high thoracic spinal cord injury often results in autonomic dysreflexia, a condition characterized by exaggerated spinal reflexes and episodic hypertension, that may be caused by reorganization of synapses on sympathetic preganglionic neurons after loss of supraspinal input. To assess remodelling of synapt...

journal_title：Neuroscience

authors： Weaver LC,Cassam AK,Krassioukov AV,Llewellyn-Smith IJ

更新日期：1997-11-01 00:00:00

abstract：:Wobbler mice display forelimb weakness, altered paw positioning, reduced running speed, muscle atrophy and motor neuron loss; co-treatment with glycosaminoglycans and insulin-like growth factor-I counteracts the progression of the disease. Reportedly, treatment with glycosaminoglycans or insulin-like growth factor-I s...

journal_title：Neuroscience

authors： Vergani L,Losa M,Lesma E,Di Giulio AM,Torsello A,Müller EE,Gorio A

更新日期：1999-01-01 00:00:00

abstract：:Ghrelin is a peptide produced in the gut with a wide range of physiological functions. Recent studies have suggested it may have potential as a neuroprotective agent in models of Parkinson's disease, reducing the impact of toxic challenges on the survival of nigral dopaminergic neurons. The presence of the ghrelin rec...

journal_title：Neuroscience

authors： Elabi OF,Duskova K,Davies JS,Lane EL

更新日期：2018-12-15 00:00:00

abstract：:Three-dimensional changes in the angular orientation of the head were monitored during galvanic vestibular stimulation (GVS) delivered through electrodes implanted bilaterally in the tensor tympani muscle of the guinea-pig middle ear. Bilateral GVS was delivered by passing current between both ears with the anode situ...

journal_title：Neuroscience

authors： Kim J

更新日期：2013-12-03 00:00:00

abstract：:Perineuronal nets (PNNs) are a form of aggregate Extracellular Matrix (ECM) in the brain. Recent evidence suggests that the postnatal deposition of PNNs may play an active role in regulating neuroplasticity and, potentially, neurological disorders. Observations of high levels of PNN expression around somas, proximal d...

journal_title：Neuroscience

authors： Chu P,Abraham R,Budhu K,Khan U,De Marco Garcia N,Brumberg JC

更新日期：2018-09-15 00:00:00

abstract：:Little is known about the projections from the orofacial areas of the secondary somatosensory cortex (S2) to the pons and medulla including the second-order somatosensory neuron pools. To address this in rats, we first examined the distribution of S2 neurons projecting to the trigeminal principal nucleus (Vp) or oral ...

journal_title：Neuroscience

authors： Haque T,Akhter F,Kato T,Sato F,Takeda R,Higashiyama K,Moritani M,Bae YC,Sessle BJ,Yoshida A

更新日期：2012-09-06 00:00:00

abstract：:Synaptic vesicle protein 2A (SV2A), which plays an important role in the pathophysiology of epilepsy, is a unique vesicular protein recognized as a pharmacological target of anticonvulsant drugs. Furthermore, SV2A is a potential synaptic density marker, as it is ubiquitously expressed throughout the brain in all nerve...

journal_title：Neuroscience

authors： Mendoza-Torreblanca JG,García-Cruz ME,Sánchez-Cruz I,Gomez-Gonzalez B,Juárez-Méndez S,Gómez-Lira G

更新日期：2019-11-01 00:00:00

abstract：:Remyelination is common under physiological conditions and usually occurs as a response to a pathological demyelinating event. Its potentiation is an important goal for the development of therapies against pathologies such as multiple sclerosis and white matter injury. Visualization and quantification in vivo of demye...

journal_title：Neuroscience

authors： Cisneros-Mejorado AJ,Garay E,Ortiz-Retana J,Concha L,Moctezuma JP,Romero S,Arellano RO

更新日期：2020-07-15 00:00:00