Muscle resistance to slow ramp weakly depends on activation level.

Abstract:

:The mechanical response of human m. flexor pollicis longus to slow (3.2 degrees/s) linear stretch by 5.5 degrees was measured during sustained (45-60 s, 9-13.5 p.p.s.) unfused tetanus evoked by electrical stimulation. The stiffness increased during unfused tetanus. At the late phase of unfused tetanus it was 1.8 +/- 0.2 (mean +/- S.D.) times greater than at the early phase. The sensitivity of the isometric tension level to a short change in a stimulation frequency also increased. At the late phase of unfused tetanus force oscillations increased 1.2 +/- 0.2-fold during slow stretch or shortening and immediately reached a smaller amplitude after the cessation of length change. This was probably related to the friction and thixotropy in muscles. Muscle resistance to slow ramp depended only weakly on activation level. In the late phase of unfused tetanus the stiffness per unit force was 1.5 +/- 0.4 times greater at 9-13.5 p.p.s. than at 20-25 p.p.s. Thus, the relative value of muscle stiffness was greater for smaller activation levels typical for maintenance of posture. The enhancement of muscle stiffness during sustained unfused tetanus and a weak stiffness dependence on the activation level indicated a non-additivity of processes occurring in active muscle.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Gurfinkel VS,Ivanenko YP,Levik YS

doi

10.1016/s0306-4522(97)00130-9

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

299-306

issue

1

eissn

0306-4522

issn

1873-7544

pii

S0306-4522(97)00130-9

journal_volume

80

pub_type

杂志文章
  • Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia.

    abstract::Brain ischemia induces a marked response of resident microglia and hematopoietic cells including monocytes/macrophages. The present study was designed to assess the distribution of microglia/macrophages in cerebral ischemia using bone marrow chimera mice known to express enhanced green fluorescent protein (EGFP). At 2...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(02)00954-5

    authors: Tanaka R,Komine-Kobayashi M,Mochizuki H,Yamada M,Furuya T,Migita M,Shimada T,Mizuno Y,Urabe T

    更新日期:2003-01-01 00:00:00

  • Acidic FGF promotes neurite outgrowth of cortical neurons and improves neuroprotective effect in a cerebral ischemic rat model.

    abstract::Acidic fibroblast growth factor (aFGF) is a neurotrophic factor which is a powerful neuroprotective and neuroregenerative factor of the nervous system. Prior study had shown that levels of FGFs significantly increase following ischemic injury, reflecting a physiological protection mechanism. However, few reports demon...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2015.07.074

    authors: Tsai MJ,Tsai SK,Huang MC,Liou DY,Huang SL,Hsieh WH,Huang WC,Huang SS,Cheng H

    更新日期:2015-10-01 00:00:00

  • Structural changes in functionally illiterate adults after intensive training.

    abstract::About 7.5million adults in Germany cannot read and write properly despite attending school for several years. They are considered to be functional illiterates. Since the ability to read and write is crucial for being employed and socially accepted, we developed a literacy training to overcome these deficits. In this s...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2016.12.049

    authors: Boltzmann M,Mohammadi B,Samii A,Münte TF,Rüsseler J

    更新日期:2017-03-06 00:00:00

  • Immunohistochemical localization of creatine kinase BB-isoenzyme and tubulin in gerbil brain.

    abstract::Cellular distribution of creatine kinase BB-isoenzyme and tubulin was investigated immunohistochemically with tissue sections from various areas of the gerbil brain. Both the reaction for creatine kinase BB-isoenzyme and tubulin visualized nerve cell bodies, dendrites and axons. While the reaction for tubulin was simi...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(84)90183-0

    authors: Yoshimine T,Morimoto K,Homburger HA,Yanagihara T

    更新日期:1984-07-01 00:00:00

  • The cells of origin of the incertofugal projections to the tectum, thalamus, tegmentum and spinal cord in the rat: a study using the autoradiographic and horseradish peroxidase methods.

    abstract::Efferent projections of the zona incerta were examined in the rat using the autoradiographic and horseradish peroxidase methods, with special reference to the cytoarchitectonic structure of the zona incerta. Autoradiographic experiments showed that the incertofugal fiber systems reach ipsilaterally to the thalamus (la...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(82)90203-2

    authors: Watanabe K,Kawana E

    更新日期:1982-10-01 00:00:00

  • Cytochemical localization of 5'-nucleotidase activity in retinal photoreceptor cells.

    abstract::Further cytochemical studies on the ultrastructural localization of 5'-nucleotidase in the rat retina have revealed activity to be associated with the complex synapses formed by the rod spherules of the receptors and the bipolar and horizontal cell processes. Activity was also seen on the axolemma of receptor fibers. ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(84)90196-9

    authors: Kreutzberg GW,Hussain ST

    更新日期:1984-04-01 00:00:00

  • Comparing the after-effects of continuous theta burst stimulation and conventional 1 Hz rTMS on semantic processing.

    abstract::Our aim was to evaluate continuous theta burst stimulation (cTBS) as a tool to induce temporary impairment (virtual lesion) in semantic processing. Four groups with 20 subjects each were stimulated. In the three experimental groups the stimulation site was the left superior temporal cortex. Stimulation was either 1Hz ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2012.12.033

    authors: Brückner S,Kiefer M,Kammer T

    更新日期:2013-03-13 00:00:00

  • Inhibitory inputs to four types of spinocerebellar tract neurons in the cat spinal cord.

    abstract::Spinocerebellar tract neurons are inhibited by various sources of input via pathways activated by descending tracts as well as peripheral afferents. Inhibition may be used to modulate transmission of excitatory information forwarded to the cerebellum. However it may also provide information on the degree of inhibition...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2012.09.015

    authors: Shakya Shrestha S,Bannatyne BA,Jankowska E,Hammar I,Nilsson E,Maxwell DJ

    更新日期:2012-12-13 00:00:00

  • Action of Hydrogen Peroxide on Synaptic Transmission at the Mouse Neuromuscular Junction.

    abstract::Hydrogen peroxide (H2O2) is one of the reactive oxygen species (ROS), endogenously produced during metabolism, which acts as a second messenger. In skeletal muscles, hypoxia- or hyperthermia-induced increase in H2O2 might affect synaptic transmission by targeting the most redox-sensitive presynaptic compartment (Ginia...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2018.12.027

    authors: Giniatullin A,Petrov A,Giniatullin R

    更新日期:2019-02-10 00:00:00

  • Transganglionic degeneration of capsaicin-sensitive C-fiber primary afferent terminals.

    abstract::Local treatment of rat peripheral nerves with capsaicin induces permanent impairment of afferent C-fiber functions and changes in the response properties of spinal dorsal horn neurons. In this study a new experimental approach, the "capsaicin gap" technique, has been utilized in an attempt to unravel pathomorphologica...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(90)90286-d

    authors: Jancsó G,Lawson SN

    更新日期:1990-01-01 00:00:00

  • Long-term potentiation and memory processes in the psychological works of Sigmund Freud and in the formation of neuropsychiatric symptoms.

    abstract::Far from disproving the model of mind functioning proposed by psychoanalysis, the recent advances in neuropsychiatrical research confirmed the crucial ideas of Sigmund Freud. The hypothesis that the origin of mental illnesses lies in the impossibility for a subject to erase the long-term effects of a remote adverse ev...

    journal_title:Neuroscience

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroscience.2004.09.032

    authors: Centonze D,Siracusano A,Calabresi P,Bernardi G

    更新日期:2005-01-01 00:00:00

  • Dendritic arborization and axon trajectory of neurons in the hypothalamic arcuate nucleus of the rat--updated.

    abstract::Neurons in the hypothalamic arcuate nucleus (arcuate neurons) were traced on Golgi-impregnated sections. Dendrites of arcuate neurons showed characteristic orientation patterns. Dendrites along the lateral side follow the convex border of the nucleus by running parallel to the tanycyte processes. Neurons located in th...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(85)90005-3

    authors: Réthelyi M

    更新日期:1985-10-01 00:00:00

  • Early c-Jun N-terminal kinase-dependent phosphorylation of activating transcription factor-2 is associated with degeneration of retinal ganglion cells.

    abstract::Neuron death due to deprivation of target-derived neurotrophic factors depends on protein synthesis regulated by transcription factor activity. We investigated the content and phosphorylation of activating transcription factor 2 (ATF-2) in axon-damaged retinal ganglion cells of neonatal rats. In the retina of neonatal...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2011.01.059

    authors: Ribas VT,Arruda-Carvalho M,Linden R,Chiarini LB

    更新日期:2011-04-28 00:00:00

  • Distribution of neurotensin binding sites in the caudal brainstem of the rat: a light microscopic radioautographic study.

    abstract::Specific high-affinity neurotensin binding sites were labeled in sections of the rat caudal brainstem using a monoiodinated ligand, and their distribution was examined by light microscopic radioautography after fixation with glutaraldehyde. In the medulla, labeled binding sites were mainly concentrated within the dors...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(87)90282-x

    authors: Kessler JP,Moyse E,Kitabgi P,Vincent JP,Beaudet A

    更新日期:1987-10-01 00:00:00

  • Microglia Regulate Cell Genesis in a Sex-dependent Manner in the Neonatal Hippocampus.

    abstract::Microglia, the innate immune cells of the brain, regulate brain development through many processes such as synaptic pruning, supporting cell genesis and phagocytosing living and dying cells. There are sex differences in these same developmental processes throughout the brain, thus microglia may contribute to brain sex...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2020.10.009

    authors: Nelson LH,Peketi P,Lenz KM

    更新日期:2021-01-15 00:00:00

  • Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions.

    abstract::Field and intracellular potentials were recorded from CA1 pyramidal stratum in submerged slices (at 33 degrees). During "normal" oxygenation (95% O2 + 5% CO2), tonic depression of population spikes and field excitatory postsynaptic potentials by endogenous adenosine was demonstrated by (i) the marked enhancement by th...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(94)90545-2

    authors: Zhu PJ,Krnjević K

    更新日期:1994-11-01 00:00:00

  • Facilitated induction of hippocampal long-term potentiation in slices perfused with low concentrations of magnesium.

    abstract::The generation of long-term potentiation of synaptic transmission in area CA1 of hippocampal slices of the guinea-pig has been examined in solutions containing low concentrations of magnesium ions. It was found that the induction of long-term potentiation is greatly facilitated in slices perfused with 0.1 mM magnesium...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(87)90193-x

    authors: Huang YY,Wigström H,Gustafsson B

    更新日期:1987-07-01 00:00:00

  • Differential expression of polycytosine-binding protein isoforms in adrenal gland, locus coeruleus and midbrain.

    abstract::Polycytosine-binding proteins (PCBPs) are RNA-binding proteins that participate in post-transcriptional control pathways. Among the diverse functions of these proteins is the interaction with a 27 nucleotide pyrimidine-rich domain within the 3'UTR of tyrosine hydroxylase (TH) mRNA. Mutations to this domain result in d...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2014.11.038

    authors: Boschi NM,Takeuchi K,Sterling C,Tank AW

    更新日期:2015-02-12 00:00:00

  • Immunohistochemical evidence for a spinothalamic pathway co-containing cholecystokinin- and galanin-like immunoreactivities in the rat.

    abstract::Using indirect immunofluorescence technique combined with retrograde tracing as well as surgical lesions, a system of spinothalamic neurons containing both galanin- and cholecystokinin-like immunoreactivity has been defined. The cell bodies are located in the lumbar segments L1-L5 with a preferential localization dors...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(87)90103-5

    authors: Ju G,Melander T,Ceccatelli S,Hökfelt T,Frey P

    更新日期:1987-02-01 00:00:00

  • Pre- and postsynaptic modulation of glycinergic and gabaergic transmission by muscarinic receptors on rat hypoglossal motoneurons in vitro.

    abstract::The motor output of hypoglossal motoneurons to tongue muscles takes place in concert with the respiratory rhythm and is determined by the balance between excitatory glutamatergic transmission and inhibitory transmission mediated by glycine or GABA. The relative contribution by these transmitters is a phasic phenomenon...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2004.09.046

    authors: Pagnotta SE,Lape R,Quitadamo C,Nistri A

    更新日期:2005-01-01 00:00:00

  • Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation.

    abstract::In the adult CNS, GABA is the predominant inhibitory neurotransmitter, mediating the hyperpolarization of membrane potential and regulating the glutamatergic activity. In the immature CNS, on the other hand, GABA mediates depolarization and is involved in controlling morphogenesis. This developmental shift in GABA act...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2006.08.044

    authors: Takayama C,Inoue Y

    更新日期:2006-12-01 00:00:00

  • Regional Fos-expression induced by γ-hydroxybutyrate (GHB): comparison with γ-butyrolactone (GBL) and effects of co-administration of the GABAB antagonist SCH 50911 and putative GHB antagonist NCS-382.

    abstract::γ-Hydroxybutyrate (GHB) has a complex array of neural actions that include effects on its own high-affinity GHB receptor, the release of neuroactive steroids, and agonist actions at GABAA and GABAB receptors. We previously reported partial overlap in the c-Fos expression patterns produced by GHB and the GABAB agonist,...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2014.07.056

    authors: van Nieuwenhuijzen PS,McGregor IS,Chebib M,Hunt GE

    更新日期:2014-09-26 00:00:00

  • Maternal separation and proclivity for ethanol intake: a potential role of the endocannabinoid system in rats.

    abstract::Maternal separation (MS) during the first postnatal weeks induces alcohol intake and a reduction in the expression of glucocorticoid receptors (GR). Adults' alcohol consumption may depend on changes in the endocannabinoid system (eCBs). Our goal was to evaluate the status of the eCBs before the exposition to alcohol t...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2012.07.071

    authors: Romano-López A,Méndez-Díaz M,Ruiz-Contreras AE,Carrisoza R,Prospéro-García O

    更新日期:2012-10-25 00:00:00

  • Effects of paired-pulse and repetitive stimulation on neurons in the rat medial geniculate body.

    abstract::Many behaviorally relevant sounds, including language, are composed of brief, rapid, repetitive acoustic features. Recent studies suggest that abnormalities in producing and understanding spoken language are correlated with abnormal neural responsiveness to such auditory stimuli at higher auditory levels [Tallal et al...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(02)00240-3

    authors: Bartlett EL,Smith PH

    更新日期:2002-01-01 00:00:00

  • Quantitative autoradiographic mapping of neurohypophysial hormone binding sites in the rat forebrain and pituitary gland--I. Characterization of different types of binding sites and their distribution in the Long-Evans strain.

    abstract::Oxytocin and vasopressin binding sites were localized and characterized by quantitative autoradiography on consecutive sections of Long-Evans rat forebrains and pituitary glands, incubated in the presence of 5 nM [3H]oxytocin or 5 nM [3H]vasopressin. In the forebrain, two types of neurohypophysial hormone binding site...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(88)90143-1

    authors: Freund-Mercier MJ,Stoeckel ME,Dietl MM,Palacios JM,Richard P

    更新日期:1988-07-01 00:00:00

  • Structural and quantitative analysis of astrocytes in the mouse hippocampus.

    abstract::We revealed the structural features of astrocytes by means of light microscopy, confocal laser scanning microscopy and high voltage electron microscopy, and estimated their numerical densities in the mouse hippocampus. The high voltage electron microscope examinations of Golgi-impregnated astrocytes clearly disclosed ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/s0306-4522(02)00041-6

    authors: Ogata K,Kosaka T

    更新日期:2002-01-01 00:00:00

  • Inhibition by endomorphin-1 and endomorphin-2 of excitatory transmission in adult rat substantia gelatinosa neurons.

    abstract::Intrathecally-administered endomorphin-1 and endomorphin-2 produce antinociceptive effects which are different from each other. In order to elucidate a cellular basis for this result, we examined the effects of endomorphin-1 and endomorphin-2 on holding currents and spontaneous glutamatergic excitatory transmission in...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2006.01.010

    authors: Fujita T,Kumamoto E

    更新日期:2006-01-01 00:00:00

  • The optic tectum of gymnotiform teleosts Eigenmannia virescens and Apteronotus leptorhynchus: a Golgi study.

    abstract::Golgi, Nissl, Bielschowsky and cholinesterase techniques have been used to analyze the optic tectum of the weakly electric teleost fish Eigenmannia virescens and Apteronotus leptorhynchus. Six layers are readily distinguished: a fairly thick stratum marginale, a narrow stratum opticum and stratum fibrosum et griseum s...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/0306-4522(86)90190-9

    authors: Sas E,Maler L

    更新日期:1986-05-01 00:00:00

  • Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.

    abstract::Recent studies have demonstrated that astrocytes express a variety of ion channels and neurotransmitter receptors and can modulate the activity of neurons. Since a single astrocyte makes tight contacts with many neighboring neuronal cells, they can provide efficient and wide modulation of neuronal networks. Here, we p...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2005.04.024

    authors: Yamazaki Y,Hozumi Y,Kaneko K,Li J,Fujii S,Miyakawa H,Kudo Y,Kato H

    更新日期:2005-01-01 00:00:00

  • Dopamine D1-like receptor activation depolarizes medium spiny neurons of the mouse nucleus accumbens by inhibiting inwardly rectifying K+ currents through a cAMP-dependent protein kinase A-independent mechanism.

    abstract::Dopamine/cAMP signaling has been reported to mediate behavioral responses related to drug addiction. It also modulates the plasticity and firing properties of medium spiny neurons (MSNs) in the nucleus accumbens (NAc), although the effects of cAMP signaling on the resting membrane potential (RMP) of MSNs has not been ...

    journal_title:Neuroscience

    pub_type: 杂志文章

    doi:10.1016/j.neuroscience.2010.02.075

    authors: Podda MV,Riccardi E,D'Ascenzo M,Azzena GB,Grassi C

    更新日期:2010-05-19 00:00:00