Abstract:
:Golgi, Nissl, Bielschowsky and cholinesterase techniques have been used to analyze the optic tectum of the weakly electric teleost fish Eigenmannia virescens and Apteronotus leptorhynchus. Six layers are readily distinguished: a fairly thick stratum marginale, a narrow stratum opticum and stratum fibrosum et griseum superficiale, a well-developed stratum griseum centrale, a stratum album centrale and a compact stratum periventriculare. Fifty-six neuronal types are present. In regard to comparative aspects of tectal organization, it became apparent that although most neuronal types are similar to those reported in other teleostean fish, there are certain obvious differences such as: pyramidal cell somata not confined to stratum fibrosum et griseum superficiale, but also clustered in the adjacent stratum opticum, presenting stratified or diffuse basilar dendritic arbors; and a change from vertical to oblique and almost horizontal neuronal orientation in the ventral and caudal tectum. The presence of pyramidal cells with aligned and misaligned apical and basal dendritic fields. A cell of stratum griseum centrale with an ascending axon to stratum opticum. A special projection type of fusiform cell of stratum griseum centrale, with an efferent axon of somatic origin. A cell rich stratum griseum centrale, with a wider variety of multipolar and bipolar cell population than reported in other teleosts. Fourteen types of pyriform cells are present, four of which are efferent. Our observations are suggestive of regional differences in regard to the caudalmost tectum in Apteronotus: presumably this is related to the extremely sparse retinal input to this part of the tectum. A close functional correlation has been found between some multipolar and pyriform cells identified in our material with similar cells reported by Rose and Heiligenberg as multisensory cells, following recordings and horseradish peroxidase fillings of these cells. Based on the observation of patchy torus semicircularis input to stratum fibrosum et griseum superficiale, disjunct from the retinal input to this layer, it is proposed that perhaps this arrangement is the result of competition for synaptic targets during development.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Sas E,Maler Ldoi
10.1016/0306-4522(86)90190-9subject
Has Abstractpub_date
1986-05-01 00:00:00pages
215-46issue
1eissn
0306-4522issn
1873-7544pii
0306-4522(86)90190-9journal_volume
18pub_type
杂志文章相关文献
NEUROSCIENCE文献大全abstract::The neuropeptide oxytocin (OT) has been implicated in a range of mammalian reproductive and social behaviors including parent-offspring bonding and partner preference formation between socially monogamous mates. Its role in mediating non-reproductive social relationships in rodents, however, remains largely unexplored...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2010.05.023
更新日期:2010-08-25 00:00:00
abstract::In the present study the time-course of DNA fragmentation following insulin-induced hypoglycemia was examined. In situ localization of DNA breaks were studied by the terminal deoxynucleotidyl transferase-mediated biotin-deoxyuridine triphosphate nick-end labelling method, and the temporal profile of DNA-fragmentation ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(98)00559-4
更新日期:1999-01-01 00:00:00
abstract::Skilled performance and acquisition is dependent upon afferent input to motor cortex. The present study used short-latency afferent inhibition (SAI) to probe how manipulation of sensory afference by attention affects different circuits projecting to pyramidal tract neurons in motor cortex. SAI was assessed in the firs...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2017.07.028
更新日期:2017-09-17 00:00:00
abstract::The known genetic mutation causing Huntington's disease (HD) makes this disease an important model to study links between gene and brain function. An autosomal dominant family history and the availability of a sensitive and specific genetic test allow pre-clinical diagnosis many years before the onset of any typical c...
journal_title:Neuroscience
pub_type: 杂志文章,评审
doi:10.1016/j.neuroscience.2009.01.045
更新日期:2009-11-24 00:00:00
abstract::The purpose of this study was to investigate the effect of dopamine on the function of synapses formed by cholinergic neurons derived from the rat retina. We used an experimental culture system in which rat striated muscle cells served as postsynaptic targets for cholinergic neurons of the retina. This culture system ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90104-0
更新日期:1984-11-01 00:00:00
abstract::Hippocampal sclerosis is the most frequent pathology encountered in mesial temporal structures resected from patients with intractable temporal lobe epilepsy and it mainly involves hippocampal neuronal loss and gliosis. These alterations are accompanied by changes in the expression of a variety of molecules in the sur...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2007.07.029
更新日期:2007-10-12 00:00:00
abstract::The present study was designed to assess the possibility that sub-total ventral hippocampal lesions might leave intact a mechanism for only highly accurate navigation, whereas sub-total dorsal hippocampal lesions might leave intact a mechanism only for less precise navigation. Animals with selective dorsal, ventral or...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2004.05.007
更新日期:2004-01-01 00:00:00
abstract::A single session of aerobic exercise may offer one means to "prime" motor regions to be more receptive to the acquisition of a motor skill; however, the mechanisms whereby this priming may occur are not clear. One possible explanation may be related to the post-translational modification of plasticity-related receptor...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2019.05.051
更新日期:2019-08-01 00:00:00
abstract::Fat, ethanol, and nicotine share a number of properties, including their ability to reinforce behavior and produce overconsumption. To test whether these substances act similarly on the same neuronal populations in specific brain areas mediating these behaviors, we administered the substances short-term, using the sam...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2014.07.050
更新日期:2014-09-26 00:00:00
abstract::Small (SK) and intermediate (IK) conductance calcium-activated potassium channels are candidate ion channels for the regulation of excitability in nociceptive neurones. We have used unique peptide-directed antisera to describe the immunocytochemical distribution of the known isoforms of these ion channels in dorsal ro...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2004.09.062
更新日期:2005-01-01 00:00:00
abstract::Transient outward rectifying conductances or A-like conductances in sympathetic preganglionic neurons (SPN) are prolonged, lasting for hundreds of milliseconds to seconds and are thought to play a key role in the regulation of SPN firing frequency. Here, a multidisciplinary electrophysiological, pharmacological and mo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2010.12.061
更新日期:2011-03-31 00:00:00
abstract::A lesion of the entorhinal cortex produces a loss of more than 80% of the synapses in the outer molecular layer of the hippocampus in the rat. However, this synaptic loss is transient. Beginning a few days after denervation, new synapses are formed, virtually replacing the lost inputs within two months. Synaptic remod...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(94)90434-0
更新日期:1994-08-01 00:00:00
abstract::Clinical and experimental evidence indicates that exposure to alcohol in utero is associated with altered immune capacity. The mechanisms underlying such abnormalities are not clear. However, the suggestion that reciprocal interactions between the immune and the nervous systems are necessary for a competent immune res...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(90)90133-o
更新日期:1990-01-01 00:00:00
abstract::Adrenomedullin (AM) belongs to a calcitonin gene-related peptide (CGRP) family and has been demonstrated to recruit CGRP following chronic use of morphine and neuronal nitric oxide synthase (nNOS) in inflammation. The present study investigated the possibility that AM initiates the changes of other molecules contribut...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2014.08.048
更新日期:2014-11-07 00:00:00
abstract::Vagal afferents ascending from the gastrointestinal tract synapse on neurons in the nucleus of the solitary tract. Although these neurons constitute a significant proportion of solitary tract cells their firing behaviour and synaptic properties are not documented. Since gastrointestinal tract afferent termination site...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(99)00416-9
更新日期:2000-01-01 00:00:00
abstract::The human brain is composed of complex networks of 100 billion neurons that underlie its higher functions. The set of neural connections in the brain has recently attracted growing interest from the scientific community. It is important to identify individual differences in these neural connections to study the backgr...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.06.032
更新日期:2015-08-20 00:00:00
abstract::A new double-label autoradiographic glucose analog method for the sequential measurement of altered regional cerebral metabolic rates for glucose in the same animal is presented. This method is based on the sequential injection of two boluses of glucose tracer labeled with two different isotopes (short-lived 18F and l...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90357-5
更新日期:1987-08-01 00:00:00
abstract::Chronic psychosocial stress is an important environmental risk factor for the development of psychiatric diseases. However, studying the impact of chronic psychosocial stress in mice is time consuming and thus not optimally suited to 'screen' increasing numbers of genetically manipulated mouse models for psychiatric e...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.11.043
更新日期:2016-02-09 00:00:00
abstract::The electrical activity of 132 neurons located in the inhibitory area of the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis and ventralis has been recorded in precollicular decerebrate cats during sinusoidal displacement of the neck. This was ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(84)90038-1
更新日期:1984-02-01 00:00:00
abstract::Dephosphorylation by the Ca2+/calmodulin-dependent phosphatase calcineurin has been suggested as an important mechanism of Ca2+-dependent inactivation of voltage-gated Ca2+ channels. We have tested whether calcineurin plays a role in the inactivation process of two types of high-voltage-activated Ca2+ channels (L and ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(99)00434-0
更新日期:2000-01-01 00:00:00
abstract::To study the effect of inositol 1,4,5-trisphosphate (IP(3)) in isolated frog vomeronasal microvillar receptor neurones, whole-cell recordings were performed with 0.5 microM caged IP(3) dissolved in the pipette solution. IP(3) was released by photolysis of caged IP(3) initiated by a 0.8-ms ultraviolet flash from a xeno...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(03)00115-5
更新日期:2003-01-01 00:00:00
abstract::The extent to which glutamate receptors in the nucleus accumbens and ventral tegmental area regulate feeding-evoked increases in dopamine release in the nucleus accumbens was determined using in vivo brain microdialysis in the rat. In some animals a second dialysis probe was implanted in the ventral tegmental area ips...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(96)00450-2
更新日期:1997-02-01 00:00:00
abstract::We describe the immunocytochemical distribution of adenosine A1 receptors in the rat hippocampus. Adenosine A1 receptor-like immunoreactivity was seen on the cell soma and dendrites of pyramidal cells and the cell soma and proximal part of dendrites of granule cells, but not on glial cells. Developmentally, adenosine ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(99)00179-7
更新日期:1999-01-01 00:00:00
abstract::Substance P is an important neuropeptide neurotransmitter in the central, autonomic and enteric nervous systems. In sympathetic ganglia, substance P is thought to play a role in modulating synaptic transmission. Release of substance P by neuronal stimulation or direct application of substance P to ganglionic neurons i...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(97)00027-4
更新日期:1997-08-01 00:00:00
abstract::Interactions between neurotransmitters and the immune system represent new prospects for understanding neuroinflammation and associated neurological disease. GABA is the chief inhibitory neurotransmitter but its actions on immune pathways in the brain are unclear. In the present study, we investigated GABAergic transp...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2014.04.037
更新日期:2014-07-25 00:00:00
abstract::TREK-1 is a member of the two-pore-domain potassium channel family which is expressed predominantly in the CNS. Using an anti-peptide polyclonal antiserum, we have determined the distribution of TREK-1 in the brain and spinal cord of adult rats. Specificity of the antiserum was tested using a TREK-1-transfected cell l...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00030-6
更新日期:2001-01-01 00:00:00
abstract::We had previously shown that in rat spinal cord motoneurons urotensin II (UII) precursor mRNA was down-regulated by androgens. Very recently, a gene encoding the precursor of a UII analog, termed UII-related peptide (URP), has been identified. Using in situ hybridization, we studied the localization of UII and URP pre...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2004.12.045
更新日期:2005-01-01 00:00:00
abstract::During periods of high-frequency stimulation the maintenance of synaptic transmission depends on a continued supply of synaptic vesicles. Local recycling in the terminals ensures synaptic vesicle replenishment, but the intermediate steps are still a matter of debate. We analyzed changes in synaptic vesicle pools and e...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00450-x
更新日期:2002-01-01 00:00:00
abstract::Seizures produced by pilocarpine given i.p. to rats provide an animal model for studying the initiation, spread and generalisation of convulsive activity within the forebrain. Pilocarpine, 380 mg/kg, produces a sequence of behavioural and electroencephalographic alterations indicative of motor limbic seizures and stat...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(86)90179-x
更新日期:1986-05-01 00:00:00
abstract::Several lines of evidence suggest that integrin receptors play a pivotal role in consolidation of long-term potentiation (LTP), but which of the many integrin dimers are involved remains to be discovered. The present study used an LTP reversal paradigm to test if alpha3 integrins make an important contribution. Functi...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00540-1
更新日期:2002-01-01 00:00:00