Dopamine regulates synaptic transmission mediated by cholinergic neurons of the rat retina.

abstract：:8-oxoguanine DNA glycosylase and Kin17 are proteins widely distributed and phylogenetically conserved in the CNS. 8-oxoguanine DNA glycosylase is a DNA repair enzyme that excises 7,8-dihydro-8-oxoguanine present in DNA damaged by oxidative stress. Kin17 protein is involved in DNA repair and illegitimate recombination ...

journal_title：Neuroscience

authors： Araneda S,Pelloux S,Radicella JP,Angulo J,Kitahama K,Gysling K,Forray MI

更新日期：2005-01-01 00:00:00

abstract：:The hippocampal CA1 region receives cortical information via two main inputs: directly via the perforant (temporoammonic) path (pp-CA1 synapse) and indirectly via the tri-synaptic pathway. Although synaptic plasticity has been reported at the pp-CA1 synapse of freely behaving animals, the mechanisms underlying this ph...

journal_title：Neuroscience

authors： Aksoy-Aksel A,Manahan-Vaughan D

更新日期：2015-11-19 00:00:00

abstract：:Recently, it was reported that stimulation of the infralimbic cortex produces a feedforward inhibition of central amygdala neurons. The interest of this observation comes from the fact that the central nucleus is the main output station of the amygdala for conditioned fear responses and evidence that the infralimbic c...

journal_title：Neuroscience

authors： Berretta S,Pantazopoulos H,Caldera M,Pantazopoulos P,Paré D

更新日期：2005-01-01 00:00:00

abstract：:Neurones in the lumbosacral spinal cord are known to play a significant role in ejaculation. In these same areas neurones containing nitric oxide synthase (NOS) have been described. This raised the question as to whether there is a physiological role for nitrous oxide (NO) in the spinal cord in sexual behavior. We fir...

journal_title：Neuroscience

authors： Brack KE,Watkins N,Pyner S,Coote JH

更新日期：2007-12-05 00:00:00

abstract：:The 5-HT(6) receptor is predominantly expressed in the CNS and has been implicated in the regulation of cognitive function. Antagonists of the 5-HT(6) receptor improve cognitive performance in a number of preclinical models and have recently been found to be effective in Alzheimer's disease patients. Systemic administ...

journal_title：Neuroscience

authors： West PJ,Marcy VR,Marino MJ,Schaffhauser H

更新日期：2009-12-01 00:00:00

abstract：:Cultured neurons offer many advantages over a slice preparation for whole-cell patch-clamp studies, such as better control over the environment and space clamp control. However, heterogeneous cultures of neurons present problems in distinguishing the cell type from which recordings are made. The present study uses cor...

journal_title：Neuroscience

authors： Mynlieff M

更新日期：1999-01-01 00:00:00

abstract：:Laminar organization is a fundamental cytoarchitecture in mammalian CNS and a striking feature of the neocortex. ER81, a transcription factor, has recently been utilized as a marker of cells in the layer 5 of the neocortex. We further pursued the distribution of ER81 to investigate the identity of the ER81-expressing ...

journal_title：Neuroscience

authors： Yoneshima H,Yamasaki S,Voelker CC,Molnár Z,Christophe E,Audinat E,Takemoto M,Nishiwaki M,Tsuji S,Fujita I,Yamamoto N

更新日期：2006-01-01 00:00:00

abstract：:Astrocytes perform several functions that are essential for normal neuronal activity. They play a critical role in neuronal survival during ischemia and other degenerative injuries and also modulate neuronal recovery by influencing neurite outgrowth. In this study, we investigated the neuroprotective effects of astroc...

journal_title：Neuroscience

authors： Terashvili M,Sarkar P,Nostrand MV,Falck JR,Harder DR

更新日期：2012-10-25 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00

abstract：:Huntington's disease is a progressive, inherited neurodegenerative disorder characterized by the loss of subsets of neurons primarily in the striatum. In this study, we assessed the neuroprotective effect of lithium against striatal lesion formation in a rat model of Huntington's disease in which quinolinic acid was u...

journal_title：Neuroscience

authors： Wei H,Qin ZH,Senatorov VV,Wei W,Wang Y,Qian Y,Chuang DM

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether an objective measure of freezing of gait (FOG) using a validated alternating stepping in place (SIP) task, is related to executive and/or visuospatial cognitive impairment in Parkinson's disease (PD). METHODS:We studied prospectively 30 PD subjects with the U...

journal_title：Neuroscience

authors： Nantel J,McDonald JC,Tan S,Bronte-Stewart H

更新日期：2012-09-27 00:00:00

abstract：:In vitro receptor autoradiography was used to localize, quantify and characterize [125I-Tyr8]bradykinin binding sites in all major spinal cord segments of normal rats and animals subjected to various chemical treatments and surgical lesions. [125I-Tyr8]bradykinin specific binding sites were predominantly located to su...

journal_title：Neuroscience

authors： Lopes P,Kar S,Chrétien L,Regoli D,Quirion R,Couture R

更新日期：1995-10-01 00:00:00

abstract：:Previous research has demonstrated that diabetes induces learning and memory deficits. However, the mechanism of memory impairment induced by diabetes is poorly understood. Dietary fatty acids, especially polyunsaturated fatty acids, have been shown to enhance learning and memory and prevent memory deficits in various...

journal_title：Neuroscience

authors： Jia D,Heng LJ,Yang RH,Gao GD

更新日期：2014-01-31 00:00:00

abstract：:The effect of pairing two vibrissa stimulations on unit responses of the barrel field of the somatosensory cortex were studied in partially restrained but awake and undrugged rats. Before pairing, one of the stimulations (S2) evoked a stable, short-latency and excitatory response from the recorded unit. Depending on t...

journal_title：Neuroscience

authors： Delacour J,Houcine O,Talbi B

更新日期：1987-10-01 00:00:00

abstract：:Trigeminal neurogenic inflammation is one explanation for the development of vascular migraine. The triggers for this inflammation and pain are not well understood, but are probably vasoactive components acting on the blood vessel wall. Migraine-related inner ear symptoms like phonophobia, tinnitus, fluctuation in hea...

journal_title：Neuroscience

authors： Vass Z,Steyger PS,Hordichok AJ,Trune DR,Jancsó G,Nuttall AL

更新日期：2001-01-01 00:00:00

abstract：:Quantitative autoradiography of [3H]SCH 23390 and [3H](-)-sulpiride binding was performed in the brain of rats of various ages (3, 11 and 24 months) in order to study the changes in D1 and D2 receptor density with age. Binding of [3H]SCH 23390 in the caudate-putamen decreased progressively and markedly at rostral leve...

journal_title：Neuroscience

authors： Morelli M,Mennini T,Cagnotto A,Toffano G,Di Chiara G

更新日期：1990-01-01 00:00:00

abstract：:Specific acetylcholinesterase and non-specific cholinesterases are present in all three lobes of the rat pituitary gland. This paper describes two new observations on hypophyseal acetylcholinesterase. Firstly, a prolonged increase of neurohormone secretion evoked by dehydration and sodium loading was accompanied by a ...

journal_title：Neuroscience

authors： Alexandrova M,Holzbauer M,Racke K,Sharman DF

更新日期：1987-05-01 00:00:00

abstract：:Acute stress is known to evoke a discrete pattern of c-fos expression in the brain. The work reported here shows that this pattern is modified in regionally specific ways following repeated stress, and that this can be correlated with changes in telemetered heart rate, core temperature and corticosterone output that o...

journal_title：Neuroscience

authors： Chen X,Herbert J

更新日期：1995-02-01 00:00:00

abstract：:In the current study we analyzed the input-output relations in the entorhinal-dentate-hippocampal system, a major network involved in long-term memory. In anesthetized guinea pigs, the system was driven by activation of perforant path neurons in the entorhinal cortex (ENT), via presubicular fibers directly stimulated ...

journal_title：Neuroscience

authors： Bartesaghi R,Migliore M,Gessi T

更新日期：2006-09-29 00:00:00

abstract：:Studies in experimental animals have revealed important roles of neuroactive steroids in the control of central nervous system functions during physiological and pathological conditions, suggesting that they may represent good candidates for the development of neuroprotective strategies for neurodegenerative and psych...

journal_title：Neuroscience

authors： Melcangi RC,Panzica G,Garcia-Segura LM

更新日期：2011-09-15 00:00:00

abstract：:Endocannabinoids and somatostatin (SST) play critical roles in several pathophysiological conditions via binding to different receptor subtypes. Cannabinoid receptor 1 (CB1R) and somatostatin receptors (SSTRs) are expressed in several brain regions and share overlapping functions. Whether these two prominent members o...

journal_title：Neuroscience

authors： Zou S,Somvanshi RK,Kumar U

更新日期：2017-01-06 00:00:00

abstract：:In unanesthetized cats it has been found that pyramidal volleys elicited upon medullary pyramidal tract stimulation were capable of modifying the discharge of 41% of intracerebellar nuclear cells, via pontocerebellar systems impinging predominantly on the lateral cerebellar cortex. The incidence of responsive cells wa...

journal_title：Neuroscience

authors： Giuffrida R,Licata F,Li Volsi G,Perciavalle V,Urbano A

更新日期：1983-06-01 00:00:00

abstract：:Animals change their biological activities depending on their nutritional state. Reproductive functions, including sexual behavior, are suppressed under low-energy conditions; however, the underlying neuronal mechanism is poorly understood. Neuropeptide Y (NPY) is an orexigenic molecule released in response to low-ene...

journal_title：Neuroscience

authors： Inaba A,Komori Y,Muroi Y,Kinoshita K,Ishii T

更新日期：2016-04-21 00:00:00

abstract：:After loading cultured rat hippocampal neurons with teh acetoxymethyl ester of the Ca2+ buffer BAPTA, or its dimethyl analogue DMB, the magnitudes of transient (20-25 s) depolarization- or excitatory amino acid-induced Ca2+ responses were reduced, as were the rates of increase and recovery of [Ca2+]i. In contrast, dur...

journal_title：Neuroscience

authors： Abdel-Hamid KM,Baimbridge KG

更新日期：1997-12-01 00:00:00

abstract：:In some brain regions, previous studies reported the frequent coexistence between neuronal nitric oxide synthase (nNOS) and somatostatin (SOM). In the hippocampus, nNOS and SOM were mainly expressed in GABAergic nonprincipal neurons. Here we estimated the immunocytochemical colocalization of nNOS and SOM in the mouse ...

journal_title：Neuroscience

authors： Jinno S,Kosaka T

更新日期：2004-01-01 00:00:00

abstract：:The interaction between the dopaminergic and glutamatergic systems governs normal behavior and is perturbed in many psychiatric disorders including schizophrenia. Hypofunction of the D1 family of receptors, to which the D(1) and D(5) subtypes belong, is a typical feature of schizophrenia. Here we have used confocal li...

journal_title：Neuroscience

authors： Kruusmägi M,Kumar S,Zelenin S,Brismar H,Aperia A,Scott L

更新日期：2009-12-01 00:00:00

abstract：:Apolipoprotein E isoforms affect the risk of developing Alzheimer's disease. Apolipoprotein E-associated risk may be related to its binding to and clearance by cell surface receptors, including members of the low-density lipoprotein receptor family. We examined the brain expression of the most recently identified memb...

journal_title：Neuroscience

authors： Clatworthy AE,Stockinger W,Christie RH,Schneider WJ,Nimpf J,Hyman BT,Rebeck GW

更新日期：1999-03-01 00:00:00

abstract：:The human brain is composed of complex networks of 100 billion neurons that underlie its higher functions. The set of neural connections in the brain has recently attracted growing interest from the scientific community. It is important to identify individual differences in these neural connections to study the backgr...

journal_title：Neuroscience

authors： Takao H,Hayashi N,Ohtomo K

更新日期：2015-08-20 00:00:00

abstract：:Although numerous studies have demonstrated the neurotrophic capacity of gp130 cytokines, it remains unclear whether endogenously expressed cytokines actually function in a direct neuromodulatory manner. Therefore, using the lithium-pilocarpine status epilepticus model, we performed a detailed in situ hybridization ti...

journal_title：Neuroscience

authors： Rosell DR,Nacher J,Akama KT,McEwen BS

更新日期：2003-01-01 00:00:00

abstract：:Intracellular recordings were performed in a pontine slice preparation of the rat brain containing the locus coeruleus. The enzymatically stable P2-purinoceptor agonist alpha,beta-methylene ATP increased the firing rate without altering the amplitude or shape of action potentials; the afterhyperpolarization following ...

journal_title：Neuroscience

authors： Harms L,Finta EP,Tschöpl M,Illes P

更新日期：1992-06-01 00:00:00