Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia.

abstract：:The majority of work examining the nucleus accumbens core (NAc) has focused on functions pertaining to behaviors guided by appetitive outcomes. These studies have pointed to the NAc as being critical for motivating behavior toward desirable outcomes. For example, we have recently shown that lesions of the NAc impaired...

journal_title：Neuroscience

authors： Lichtenberg NT,Kashtelyan V,Burton AC,Bissonette GB,Roesch MR

更新日期：2014-01-31 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00

abstract：:Early gestation is a neurodevelopmental period that is especially vulnerable to environmental insult and one in which neurogenesis features prominently. Prenatal perturbation during early gestation has been linked to neuropsychiatric illnesses such as autism and schizophrenia, and severe environmental insult during th...

journal_title：Neuroscience

authors： Selemon LD,Begovic A

更新日期：2020-08-21 00:00:00

abstract：:Sigma-1 receptor (S1R) is a unique pluripotent modulator of living systems and has been reported to be associated with a number of neurological diseases including pathological pain. Intrathecal administration of S1R antagonists attenuates the pain behavior of rodents in both inflammatory and neuropathic pain models. H...

journal_title：Neuroscience

authors： Mavlyutov TA,Duellman T,Kim HT,Epstein ML,Leese C,Davletov BA,Yang J

更新日期：2016-09-07 00:00:00

abstract：:The chemoanatomical organization of the visual sector of the cat's thalamic reticular nucleus (TRN)-that is at the dorsal lateral geniculate nucleus (dLGN) and at the pulvinar nucleus (Pul)-was investigated with two novel cytoarchitectonic markers. The Wisteria floribunda agglutinin (WFA) binding reaction visualized t...

journal_title：Neuroscience

authors： Baldauf ZB

更新日期：2010-02-03 00:00:00

abstract：:The performance of a cochlear implant depends on the defined interaction between afferent neurons of the spiral ganglion and the inserted electrode. Neurite outgrowth can be induced by neurotrophins such as brain-derived neurotrophic factor (BDNF) via tropomyosin kinase receptor B (TrkB). However, neurotrophin signali...

journal_title：Neuroscience

authors： Kramer B,Tropitzsch A,Müller M,Löwenheim H

更新日期：2017-08-15 00:00:00

abstract：:Calpain-mediated tau cleavage into the neurotoxic tau45-230 fragment plays an important role in Alzheimer's disease (AD). This tau fragment accumulates mainly in the cytoplasm of degenerating neurons. However, subcellular localization studies indicated that a pool of tau45-230 associates with the cytoskeleton in hippo...

journal_title：Neuroscience

authors： Afreen S,Ferreira A

更新日期：2019-08-01 00:00:00

abstract：:Horizontal and amacrine cells in the isolated carp retina were impaled with micropipette electrode, identified by their characteristic light responses, and injected iontophoretically with markers for morphological study. Both Lucifer Yellow CH and biocytin were injected simultaneously. Lucifer Yellow was seen by its o...

journal_title：Neuroscience

authors： Teranishi T,Negishi K

更新日期：1994-03-01 00:00:00

abstract：:It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have been positively selected during human evolution and influence aspects of speech and language. Recently it was shown that when these substitutions are introduced into the endogenous Foxp2 gene of mice, they increase dendrite l...

journal_title：Neuroscience

authors： Reimers-Kipping S,Hevers W,Pääbo S,Enard W

更新日期：2011-02-23 00:00:00

abstract：:In order to determine which neurotransmitters and neuropeptides are utilized by the neurons of the mesencephalic trigeminal nucleus and by the fibres making synaptic contact with these primary sensory cells, we have set up an immunohistochemical study using antibodies against 17 major neurotransmitters and neuropeptid...

journal_title：Neuroscience

authors： Copray JC,Ter Horst GJ,Liem RS,van Willigen JD

更新日期：1990-01-01 00:00:00

abstract：:In this study, we examined the prevalence and distribution of NMDA receptor subunits within crude synaptic membranes derived from the brains of mice lacking methyl CpG binding protein 2 (MeCP2). Our results show that the distribution of NMDA receptor subunits within the detergent soluble, detergent resistant, and post...

journal_title：Neuroscience

authors： Maliszewska-Cyna E,Bawa D,Eubanks JH

更新日期：2010-07-14 00:00:00

abstract：:Kinetic properties of synaptic depression were analysed for excitatory postsynaptic potentials in neuron number 3 in the right pallial ganglion of Helix pomatia. It was observed that long-term depression did not only suppress the amplitudes of excitatory postsynaptic potentials but also changed the kinetics of short-t...

journal_title：Neuroscience

authors： Christoffersen GR,Schilhab TS

更新日期：1996-08-01 00:00:00

abstract：:The laminar binding distribution of three nicotinic receptor agonists, [3H](-)nicotine, [3H]cytisine, and [3H]epibatidine, and their relation to the [3H]vesamicol binding, which is known to represent the vesicular acetylcholine transport sites, was performed employing in vitro autoradiography on the medial temporal co...

journal_title：Neuroscience

authors： Sihver W,Gillberg PG,Svensson AL,Nordberg A

更新日期：1999-01-01 00:00:00

abstract：:N-Methyl-D-aspartate receptors are thought to be involved in synaptic signaling within the hypothalamo-neurohypophysial system, but the extent and nature of their involvement has not been determined. In this study, in the rat, we evaluated the effect of hyperosmotic stimulation on the N-methyl-D-aspartate receptor sub...

journal_title：Neuroscience

authors： Decavel C,Curras MC

更新日期：1997-05-01 00:00:00

abstract：:The present experiments examined the effects of direct intracortical microinjections of the N-methyl-D-aspartate receptor antagonist 2-amino-5-phosphonovaleric acid directly into the insular cortex of rats, before or immediately after training of conditioned taste aversion and the water maze spatial learning task. In ...

journal_title：Neuroscience

authors： Gutiérrez H,Hernández-Echeagaray E,Ramírez-Amaya V,Bermúdez-Rattoni F

更新日期：1999-03-01 00:00:00

abstract：:Lesioning of thalamic target neurons in the adult rat provokes a resorption of terminal axonal branches of afferent neurons from the dorsal column nuclei. There is, however, no massive neuronal loss in the dorsal column nuclei. In the adult, therefore, the thalamic post synaptic target cells influence primarily the ex...

journal_title：Neuroscience

authors： Marty S,Peschanski M

更新日期：1994-10-01 00:00:00

abstract：:Nitric oxide synthase is the biosynthetic enzyme for the free radical neurotransmitter nitric oxide. Using an affinity-purified antiserum, nitric oxide synthase was found to be localized to peripheral ocular nerve fibers, related cranial ganglia, and the retina of the rat. In the eye, nitric oxide synthase-like immuno...

journal_title：Neuroscience

authors： Yamamoto R,Bredt DS,Snyder SH,Stone RA

更新日期：1993-05-01 00:00:00

abstract：:Prenatal exposure to high-fat diet (HFD) might predispose offspring to develop metabolic and mental disorders later in life. Insight into the molecular and behavioral consequences of maternal HFD on offspring is sparse but may involve both neuroinflammation and a dysregulated neuroendocrine stress axis. Thus, the aim ...

journal_title：Neuroscience

authors： Winther G,Elfving B,Müller HK,Lund S,Wegener G

更新日期：2018-09-15 00:00:00

abstract：:A satisfactory management to ensure a full restoration of peripheral nerve after trauma is not yet available. Using an experimental protocol, in which crush injury was applied 1 cm above the bifurcation of the rat sciatic nerve for 20 s, we here demonstrate that the levels of neuroactive steroids, such as pregnenolone...

journal_title：Neuroscience

authors： Roglio I,Bianchi R,Gotti S,Scurati S,Giatti S,Pesaresi M,Caruso D,Panzica GC,Melcangi RC

更新日期：2008-08-26 00:00:00

abstract：:Glomeruli are functional units of the olfactory bulb responsible for early processing of odor information encoded by single olfactory receptor genes. Glomerular neural circuitry includes numerous external tufted (ET) cells whose rhythmic burst firing may mediate synchronization of bulbar activity with the inhalation c...

journal_title：Neuroscience

authors： Ma J,Lowe G

更新日期：2007-02-09 00:00:00

abstract：:Intracellular recordings were made from neurons in a rat locus coeruleus slice preparation in vitro. A postsynaptic potential was evoked by electrical stimulation of afferents to the neurons. CI-977 ([5R-(5a,7a,8b)]-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec -8-yl[-4-benzofuranacetamide monohydrochloride) cause...

journal_title：Neuroscience

authors： Pinnock RD

更新日期：1992-01-01 00:00:00

abstract：:Besides formation of neurofibrillary tangles and neuron loss, the Alzheimer's disease brain is characterized by neuritic plaques consisting of beta-amyloid peptide deposits and impaired neurotransmission. The proteins Munc18a, Munc18-interacting protein 1 and Munc18-interacting protein 2 mediate exocytosis and decreas...

journal_title：Neuroscience

authors： Jacobs EH,Williams RJ,Francis PT

更新日期：2006-01-01 00:00:00

abstract：:Neurogenesis continues throughout adult life in the mammalian olfactory epithelium. This process is a dynamic state of proliferation, differentiation and cell death, probably regulated by autocrine and paracrine signals such as peptide growth factors. Previous investigations have demonstrated roles for some growth fac...

journal_title：Neuroscience

authors： Newman MP,Féron F,Mackay-Sim A

更新日期：2000-01-01 00:00:00

abstract：:The expression of the messenger RNAs encoding N-methyl-D-aspartate receptor subunits in neurologically normal post-mortem human brain was studied by in situ hybridization. In the caudate, putamen and nucleus accumbens strong hybridization signals were observed for N-methyl-D-aspartate R1-1 messenger RNA but much weake...

journal_title：Neuroscience

authors： Rigby M,Le Bourdellès B,Heavens RP,Kelly S,Smith D,Butler A,Hammans R,Hills R,Xuereb JH,Hill RG,Whiting PJ,Sirinathsinghji DJ

更新日期：1996-07-01 00:00:00

abstract：:Respiratory disturbances are a primary phenotype of the neurological disorder, Rett syndrome (RTT), caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Mouse models generated with null mutations in Mecp2 mimic respiratory abnormalities in RTT girls. Large deletions, however, are see...

journal_title：Neuroscience

authors： Bissonnette JM,Schaevitz LR,Knopp SJ,Zhou Z

更新日期：2014-05-16 00:00:00

abstract：:Ochratoxin A (OTA), a mycotoxin and widespread food contaminant, is known for its patent nephrotoxicity and potential neurotoxicity. Previous observations in vitro showed that in the CNS, glial cells were particularly sensitive to OTA. In the search for the molecular mechanisms underlying OTA neurotoxicity, we investi...

journal_title：Neuroscience

authors： Zurich MG,Lengacher S,Braissant O,Monnet-Tschudi F,Pellerin L,Honegger P

更新日期：2005-01-01 00:00:00

abstract：:Induction of heat-shock protein-70 was studied using in situ hybridization and immunohistochemistry in the adult rat at different times following intraperitoneal injection of kainate. Marked expression of heat-shock protein-70 messenger RNA was observed during the first 24 h, followed by residual signal at 48 h. Induc...

journal_title：Neuroscience

authors： Ferrer I,Planas AM

更新日期：1995-12-01 00:00:00

abstract：:An odorant's code is represented by activity in a dispersed ensemble of olfactory sensory neurons in the nose, activation of a specific combination of groups of mitral cells in the olfactory bulb and is considered to be mapped at divergent locations in the olfactory cortex. We present here an in vitro model of the mam...

journal_title：Neuroscience

authors： Markopoulos F,Neubauer FB,Berger T,Scotti AL

更新日期：2008-10-28 00:00:00

abstract：:Hindbrain dorsal vagal complex A2 noradrenergic signaling represses the pre-ovulatory luteinizing hormone (LH) surge in response to energy deficiency. Insulin-induced hypoglycemia augments A2 neuron adenosine 5'-monophosphate-activated protein kinase (AMPK) activity and estrogen receptor-beta (ERβ) expression, coincid...

journal_title：Neuroscience

authors： Briski KP,Shrestha PK

更新日期：2016-09-07 00:00:00

abstract：:The post-stroke angiogenic response is accompanied by changes of tight junctions (TJs) of the blood-brain barrier (BBB). However, the precise dynamic change of TJ proteins (TJPs) in the different stages of stroke-induced vascular remodeling and the molecules mediating these processes have yet to be fully defined. To i...

journal_title：Neuroscience

authors： Sun J,Yu L,Huang S,Lai X,Milner R,Li L

更新日期：2017-10-24 00:00:00