Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood.

abstract：:The primary aim of this study was to investigate the effect of different training types and secondary to test gender differences on the training-related cortical plasticity induced by three different tongue-training paradigms: (1) therapeutic tongue exercises (TTE), (2) playing computer games with the tongue using the...

journal_title：Neuroscience

authors： Kothari M,Svensson P,Jensen J,Kjærsgaard A,Jeonghee K,Nielsen JF,Ghovanloo M,Baad-Hansen L

更新日期：2013-08-29 00:00:00

abstract：:Animal studies have revealed that chronic stress shifts cognitive strategies from the flexible goal-directed action to the simple and rigid habit action. In addition, stress-induced atrophy in the prefrontal cortex and dorsomedial striatum which are involved in the goal-directed action and hypertrophy of the dorsolate...

journal_title：Neuroscience

authors： Ohira H,Matsunaga M,Kimura K,Murakami H,Osumi T,Isowa T,Fukuyama S,Shinoda J,Yamada J

更新日期：2011-10-13 00:00:00

abstract：:The sensitivity of Purkinje cells to short pulse applications of L-aspartate, L-glutamate and related derivatives in their dendritic fields was tested in normal and staggerer mutant mice using cerebellar slices maintained in vitro. In normal mice, the response of Purkinje cells to L-aspartate and L-glutamate consisted...

journal_title：Neuroscience

authors： Dupont JL,Fournier E,Gardette R,Crepel F

更新日期：1984-06-01 00:00:00

abstract：:The tachykinin peptide substance P (SP) is expressed by many interneurons and some projection neurons in the superficial dorsal horn of the spinal cord. We have recently shown that SP-expressing excitatory interneurons in lamina II correspond largely to a morphological class known as radial cells. However, little is k...

journal_title：Neuroscience

authors： Polgár E,Bell AM,Gutierrez-Mecinas M,Dickie AC,Akar O,Costreie M,Watanabe M,Todd AJ

更新日期：2020-12-01 00:00:00

abstract：:Several lines of clinical evidence support the idea that fragile X syndrome (FXS) may involve a dysregulation of hypothalamic-pituitary-adrenal axis function [Wisbeck et al. (2000) J Dev Behav Pediatr 21:278-282; Hessl et al. (2002) Psychoneuroendocrinology 27:855-872]. We had tested this idea in a mouse model of FXS ...

journal_title：Neuroscience

authors： Qin M,Xia Z,Huang T,Smith CB

更新日期：2011-10-27 00:00:00

abstract：:Clozapine, an atypical antipsychotic agent important for the treatment of schizophrenia, has marked inhibitory effects on sympathetic outflow to the thermoregulatory cutaneous circulation. In rabbits clozapine reverses ear pinna vasoconstriction induced either by administration of MDMA (3,4-methylenedioxymethamphetami...

journal_title：Neuroscience

authors： Blessing WW,Zilm A,Ootsuka Y

更新日期：2006-09-15 00:00:00

abstract：:The transition from multipotent neural stem cells (NSCs) to terminally differentiated neurons is a multistep process, and the transition is finely regulated by transcription factors with basic helix-loop-helix (bHLH) motifs. Melatonin is an endogenous neurohormone with profound neurotrophic and neuroprotective effects...

journal_title：Neuroscience

authors： Li X,Chen X,Zhou W,Ji S,Li X,Li G,Liu G,Wang F,Hao A

更新日期：2017-11-19 00:00:00

abstract：:Chronic administration of mu-opioid receptor agonists is known to produce adaptive changes within noradrenergic neurons of the locus coeruleus. Although mu-opioid receptors are densely expressed by locus coeruleus neurons, the effects of acute and chronic administration of agonists on the subcellular distribution of m...

journal_title：Neuroscience

authors： Van Bockstaele EJ,Commons KG

更新日期：2001-01-01 00:00:00

abstract：:The increase in excitatory outflow from the medial prefrontal cortex is critical to the development of sensitization to amphetamine. There is evidence that psychostimulant-induced changes in dopamine-GABA interactions are key to understanding the behaviorally sensitized response. The objective of this study was to cha...

journal_title：Neuroscience

authors： Morshedi MM,Meredith GE

更新日期：2007-11-09 00:00:00

abstract：:The present study was undertaken to investigate the possible effects of Spantide [D-Arg1, D-Trp7,9 Leu11]-substance P, a substance P antagonist, and of somatostatin on spinal cord blood flow. The experiments were performed with the laser-doppler technique on the L1 spinal cord segment exposed by laminectomy. The effec...

journal_title：Neuroscience

authors： Freedman J,Post C,Kåhrström J,Ohlen A,Mollenholt P,Owman C,Alari L,Hökfelt T

更新日期：1988-10-01 00:00:00

abstract：:κ opioid receptor agonists produce aversive effects in rodents, however the underlying mechanisms remain unclear. Activation of p38 mitogen-activated protein kinase (MAPK) has been discovered to play a critical role in the modulation of affective behaviors. The present study was undertaken to detect the possible invol...

journal_title：Neuroscience

authors： Zan GY,Wang Q,Wang YJ,Chen JC,Wu X,Yang CH,Chai JR,Li M,Liu Y,Hu XW,Shu XH,Liu JG

更新日期：2016-04-21 00:00:00

abstract：:Sensory events in the space around us trigger specific motor patterns directed toward or away from the spatial location of the sensory source. Spatially-defined sensorimotor associations are well-known in the visual domain but less so for the auditory modality. In particular no spatially-directed audio-motor associati...

journal_title：Neuroscience

authors： Cattaneo L,Barchiesi G

更新日期：2015-09-24 00:00:00

abstract：:The development of the catecholaminergic system in the hypothalamus and in the septal region was studied in rats from the 12th fetal day until the 9th postnatal day. Catecholaminergic structures were visualized with pre-embedding immunocytochemistry using antiserum to tyrosine hydroxylase. An intensification of diamin...

journal_title：Neuroscience

authors： Ugrumov MV,Taxi J,Tixier-Vidal A,Thibault J,Mitskevich MS

更新日期：1989-01-01 00:00:00

abstract：:Mental function has as its cerebral basis a specific dynamic structure. In particular, cortical and limbic areas involved in "higher brain functions" such as learning, memory, perception, self-awareness and consciousness continuously need to be self-adjusted even after development is completed. By this lifelong self-o...

journal_title：Neuroscience

authors： Arendt T

更新日期：2001-01-01 00:00:00

abstract：:Since mild thermal stress seems to exert neuroprotection via induction of heat-shock protein 70 kDa (hsp70), we tested whether hsp70 would preserve striatal bioelectrical activity under conditions of mitochondrial impairment. Corticostriatal slices from rats that had undergone mild thermal stress were exposed to eithe...

journal_title：Neuroscience

authors： Tantucci M,Mariucci G,Taha E,Spaccatini C,Tozzi A,Luchetti E,Calabresi P,Ambrosini MV

更新日期：2009-10-20 00:00:00

abstract：:Regular physical exercise has been described as a good strategy for prevention or reduction of musculoskeletal pain. The Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) has been investigated as a promising target for the control of inflammatory pain. Therefore, the aim of this study was to evaluate whether ac...

journal_title：Neuroscience

authors： de Azambuja G,Botasso Gomes B,Messias LHD,Aquino BM,Jorge CO,Manchado-Gobatto FB,Oliveira-Fusaro MCG

更新日期：2020-02-10 00:00:00

abstract：:The temporal pattern of distribution of somatostatin receptor was investigated using the somatostatin analogue [125I]Tyr0-DTrp8-somatostatin14 as a ligand and compared with that of somatostatin immunoreactivity during early developmental stages in the spinal cord and the sensory derivatives in rat fetuses. Qualitative...

journal_title：Neuroscience

authors： Maubert E,Slama A,Ciofi P,Viollet C,Tramu G,Dupouy JP,Epelbaum J

更新日期：1994-09-01 00:00:00

abstract：:Before movement onset, during the reaction time, excitability of M1 is selectively modulated by somatosensory inputs, only in the movement-related muscle. If a similar mechanism operates before the onset of mental movements, then somatosensory afferent inputs are exploited during cognitive representation of movement. ...

journal_title：Neuroscience

authors： Bonassi G,Bisio A,Lagravinese G,Ruggeri P,Bove M,Avanzino L

更新日期：2019-06-15 00:00:00

abstract：:Microglia play important roles in the pathogenesis of Alzheimer's disease (AD), in part, by affecting the clearance of amyloid-β (Aβ) peptides. Most studies, however, used synthetic soluble Aβ (sAβ) at higher concentrations. The exact mechanisms underlying microglia-mediated clearance of physiological sAβ at very low ...

journal_title：Neuroscience

authors： Fu H,Liu B,Li L,Lemere CA

更新日期：2020-09-01 00:00:00

abstract：:Three structurally distinct groups of antagonists were used to test the hypothesis that integrin adhesion receptors play an essential role in consolidating (stabilizing) long term potentiation of the Schaffer collaterals in rat hippocampus. Comparisons were made of percent potentiation at antagonist-treated versus con...

journal_title：Neuroscience

authors： Chun D,Gall CM,Bi X,Lynch G

更新日期：2001-01-01 00:00:00

abstract：:Exercise has been shown to impact brain plasticity and function by involving the action of brain-derived neurotrophic factor (BDNF); however, mechanisms involved are poorly understood. Two types of BDNF coexist in the brain, the precursor (proBDNF) and its mature product (mBDNF), which preferentially bind specific rec...

journal_title：Neuroscience

authors： Ding Q,Ying Z,Gómez-Pinilla F

更新日期：2011-09-29 00:00:00

abstract：:It has recently become clear that the neurotrophic factor, nerve growth factor, interacts specifically with nociceptive sensory neurons during development and maturity. Indeed, it may serve as a critical link between inflammation and the hyperalgesia that ensues in adult animals. Nerve growth factor is normally expres...

journal_title：Neuroscience

authors： Davis BM,Lewin GR,Mendell LM,Jones ME,Albers KM

更新日期：1993-10-01 00:00:00

abstract：:Victims of minimal traumatic brain injury (mTBI) do not show clear morphological brain defects, but frequently suffer lasting cognitive deficits, emotional difficulties and behavioral disturbances. In the present study we adopted a non-invasive closed-head weight-drop mouse model to produce mTBI. We examined the effec...

journal_title：Neuroscience

authors： Zohar O,Schreiber S,Getslev V,Schwartz JP,Mullins PG,Pick CG

更新日期：2003-01-01 00:00:00

abstract：:Endothelins play a role in the regulation of astrocytic functions in brain pathologies such as hyperplasia and neurotrophic factor production. The present study examined the effects of endothelins on production of neurotrophin-3, a member of the neurotrophin family of neurotrophic factors, in cultured astrocytes and r...

journal_title：Neuroscience

authors： Koyama Y,Baba A,Matsuda T

更新日期：2005-01-01 00:00:00

abstract：:Ethanol modulates the actions of multiple neurotransmitter systems, including GABA. However, its enhancing effects on GABA signaling typically are seen only at high concentrations. In contrast, although GABA is a prominent neurotransmitter in the circadian clock of the suprachiasmatic nucleus (SCN), we see ethanol mod...

journal_title：Neuroscience

authors： McElroy B,Zakaria A,Glass JD,Prosser RA

更新日期：2009-12-01 00:00:00

abstract：:Interactions between dopamine and glutamate receptors are essential for the prefrontal cortical (PFC) and hippocampal cognitive functions. In order to understand the molecular basis of dopamine/glutamate interactions in rat PFC and hippocampus, we investigated (a) the effect of in vitro dopamine D1 receptor stimulatio...

journal_title：Neuroscience

authors： Sarantis K,Matsokis N,Angelatou F

更新日期：2009-11-10 00:00:00

abstract：:Sensory-evoked propagating waves are frequently observed in sensory cortex. However, it is largely unknown how an evoked propagating wave affects the activity evoked by subsequent sensory inputs, or how two propagating waves interact when evoked by simultaneous sensory inputs. Using voltage-sensitive dye imaging, we i...

journal_title：Neuroscience

authors： Gao X,Xu W,Wang Z,Takagaki K,Li B,Wu JY

更新日期：2012-08-02 00:00:00

abstract：:Foetal mouse hippocampal primordia from mice homozygous for the Thy-1.1 allele were transplanted into the hippocampal region of adult histocompatible mice, homozygous for the Thy-1.2 allele. After survival periods of two months to one year the transplants consisted of a discrete tissue mass, well fused with the host, ...

journal_title：Neuroscience

authors： Zhou CF,Raisman G,Morris RJ

更新日期：1985-12-01 00:00:00

abstract：:Using a semihorizontal section plane tangential to the ventral surface of the cerebral peduncle, the authors re-examined cyto-, myelo- and dendroarchitecture, acetylcholinesterase activity, afferent fibers, and efferent projection neurons of the substantia nigra pars reticulata. In the semihorizontal section plane, th...

journal_title：Neuroscience

authors： Tokuno H,Nakamura Y,Kudo M,Kitao Y

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Spasticity and rigidity are serious complications associated with spinal traumatic or ischemic injury. Clinical studies show that tizanidine (Tiz) is an effective antispasticity agent; however, the mechanism of this effect is still not clear. Tiz binds not only to α2-adrenoreceptors (AR) but also to imidazol...

journal_title：Neuroscience

authors： Fuchigami T,Kakinohana O,Hefferan MP,Lukacova N,Marsala S,Platoshyn O,Sugahara K,Yaksh TL,Marsala M

更新日期：2011-10-27 00:00:00