Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.

abstract：:Investigation of rhythmic discharges may provide insights into integrative mechanisms underlying nervous system control of effectors. We have previously shown that, in CNS-intact, anesthetized rats, cutaneous sympathetic vasoconstrictor neurones innervating thermoregulatory circulations exhibit a robust rhythmicity in...

journal_title：Neuroscience

authors： Collins DR,Gilbey MP

更新日期：2003-01-01 00:00:00

abstract：:The dose-limiting side effect of the anti-neoplastic agent, paclitaxel, is a chronic distal symmetrical peripheral neuropathy that produces sensory dysfunction (hypoesthesia and neuropathic pain) but little or no distal motor dysfunction. Similar peripheral neuropathies are seen with chemotherapeutics in the vinca alk...

journal_title：Neuroscience

authors： Xiao WH,Zheng H,Zheng FY,Nuydens R,Meert TF,Bennett GJ

更新日期：2011-12-29 00:00:00

abstract：:Repetition of visually common objects was examined in relation to prior intentional learning and memory status using a delayed match-to-sample task in humans. Both response time and two temporally separate event-related potential (ERP) components indexed repetition. The early repetition effect ( approximately 200-550 ...

journal_title：Neuroscience

authors： Guo C,Lawson AL,Jiang Y

更新日期：2007-11-23 00:00:00

abstract：:The Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD) exhibits cognitive impairment and degeneration of basal forebrain cholinergic neurons (BFCNs). Our prior studies demonstrated that maternal choline supplementation (MCS) improves attention and spatial cognition in Ts65Dn offspring, normalizes hi...

journal_title：Neuroscience

authors： Powers BE,Kelley CM,Velazquez R,Ash JA,Strawderman MS,Alldred MJ,Ginsberg SD,Mufson EJ,Strupp BJ

更新日期：2017-01-06 00:00:00

abstract：:Several isoforms of integrin subunits are expressed in Schwann cells and mediate Schwann cell interactions with axons. Here, we identify α6 and β1 integrins as heterodimeric proteins expressed in Schwann cells and define their functions in axonal regeneration. α6 and β1 integrins are induced in Schwann cells in the sc...

journal_title：Neuroscience

authors： Chang IA,Kim KJ,Namgung U

更新日期：2018-02-10 00:00:00

abstract：:Basic fibroblast growth factor is a potent trophic factor with a wide spectrum of activity at various stages of neuronal development. In our studies on the effects of select lesions on the expression of growth factors, we observed that neurons of layer VIb of the rat cerebral cortex developed immunoreactivity for basi...

journal_title：Neuroscience

authors： Gómez-Pinilla F,Cotman CW

更新日期：1992-08-01 00:00:00

abstract：:Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects upper and lower motor neurons and leads to death a few years after symptom onset. Despite its high morbidity and mortality, its underlying pathogenic mechanisms still remain poorly understood. Although there is increasing evidence for sign...

journal_title：Neuroscience

authors： Konsolaki E,Koropouli E,Tsape E,Pothakos K,Zagoraiou L

更新日期：2020-12-01 00:00:00

abstract：:Conventional extracellular recording has revealed cross-modal alterations of auditory cell activities by cutaneous electrical stimulation of the hindpaw in first- and higher-order auditory thalamic nuclei (Donishi et al., 2011). Juxta-cellular recording and labeling techniques were used in the present study to examine...

journal_title：Neuroscience

authors： Kimura A,Imbe H

更新日期：2018-02-21 00:00:00

abstract：:Many epidemiological studies support the notion that people who drink alcohol also smoke cigarettes and vice versa thereby suggesting a possible functional interaction between these two most widely used psychoactive substances. We have earlier demonstrated that direct intracerebellar (ICB) microinfusion of nicotine do...

journal_title：Neuroscience

authors： Taslim N,Al-Rejaie S,Saeed Dar M

更新日期：2008-11-11 00:00:00

abstract：:Ovarian hormones regulate pyramidal cell synapse formation and excitability and interneuronal GABAergic tone in the CA1 region of the adult female rat hippocampus. The role of 17beta-estradiol in these effects is complex and appears to involve a subset of hippocampal interneurons, which express different calcium-bindi...

journal_title：Neuroscience

authors： Nakamura NH,McEwen BS

更新日期：2005-01-01 00:00:00

abstract：:Half of the cholinergic neurons of human and primate intrinsic cardiac ganglia (ICG) have a dual cholinergic/noradrenergic phenotype. Likewise, a large subpopulation of cholinergic neurons of the mouse heart expresses enzymes needed for synthesis of norepinephrine (NE), but they lack the vesicular monoamine transporte...

journal_title：Neuroscience

authors： Hoard JL,Hoover DB,Mabe AM,Blakely RD,Feng N,Paolocci N

更新日期：2008-09-22 00:00:00

abstract：:Growth-associated protein-43, an established marker of neuronal plasticity during development and in injury, was used to characterize innervation in the normal human pancreas and changes in chronic alcohol-induced pancreatitis by using light microscopic immunocytochemistry and computer-assisted image analysis. Immunos...

journal_title：Neuroscience

authors： Fink T,Di Sebastiano P,Büchler M,Beger HG,Weihe E

更新日期：1994-11-01 00:00:00

abstract：:The effects of electrical stimulation of the hypothalamus paraventricular nucleus on the spontaneous firing of mitral and granule cells in the main olfactory bulb were examined in ovariectomized female rats under urethane anaesthesia. High-frequency stimulation (0.5-1.0 mA, 10-20 pulses at 100 Hz) of the paraventricul...

journal_title：Neuroscience

authors： Yu GZ,Kaba H,Okutani F,Takahashi S,Higuchi T,Seto K

更新日期：1996-06-01 00:00:00

abstract：:Hypocretins (orexins) are hypothalamic neuropeptides that play a crucial role in regulating sleep/wake states and autonomic functions including parasympathetic cardiac activity. We have recently demonstrated stimulation of the lateral paragigantocellular nucleus (LPGi), the nucleus which is thought to play a role in r...

journal_title：Neuroscience

authors： Dergacheva O,Philbin K,Bateman R,Mendelowitz D

更新日期：2011-02-23 00:00:00

abstract：:Astrocytic endothelin receptors are involved in the appearance of activated astrocytes upon injury of the brain [Ishikawa N. et al. (1997) Eur. J. Neurosci. 9, 895-901; Koyama Y. et al. (1999) Glia 26, 268-271]. To clarify signal transduction triggered by endothelin receptors, we examined the effects of endothelins on...

journal_title：Neuroscience

authors： Koyama Y,Yoshioka Y,Hashimoto H,Matsuda T,Baba A

更新日期：2000-01-01 00:00:00

abstract：:Hippocampal neurogenesis and associated cognitive behaviors are regulated by a number of factors including stress, inflammation, and exercise. However, the interplay between these factors remains relatively unexplored, especially across the lifespan. In the current study, the effect of social isolation stress during t...

journal_title：Neuroscience

authors： Hueston CM,Cryan JF,Nolan YM

更新日期：2017-12-04 00:00:00

abstract：:A recent series of studies in rats has demonstrated positively reinforcing and memory enhancing effects following lesions of the nucleus tuberomammillaris, which is the only known source of neuronal histamine. The aim of the present experiments was to assess whether inhibition of histaminergic neurotransmission in the...

journal_title：Neuroscience

authors： Zimmermann P,Privou C,Huston JP

更新日期：1999-01-01 00:00:00

abstract：:A neuroprotected state can be acquired by preconditioning brain with a stimulus that is subthreshold for damage (tolerance). Acquisition of tolerance involves coordinate, bi-directional changes to gene expression levels and the re-programmed phenotype is determined by the preconditioning stimulus. While best studied i...

journal_title：Neuroscience

authors： Hatazaki S,Bellver-Estelles C,Jimenez-Mateos EM,Meller R,Bonner C,Murphy N,Matsushima S,Taki W,Prehn JH,Simon RP,Henshall DC

更新日期：2007-12-05 00:00:00

abstract：:Free radicals have been implicated in a number of pathological conditions. To evaluate the neurophysiological consequences of free radical exposure, slices of hippocampus isolated from guinea-pigs were exposed to hydrogen peroxide which reacts with tissue iron to generate hydroxyl free radicals. Long-term potentiation...

journal_title：Neuroscience

authors： Pellmar TC,Hollinden GE,Sarvey JM

更新日期：1991-01-01 00:00:00

abstract：:Hypocretin/orexin (Hcrt/Orx) and melanin concentrating hormone (MCH) are peptides contained in overlapping cell groups of the lateral hypothalamus and commonly involved in regulating sleep-wake states and energy balance, though likely in different ways. To see if these neurons are similarly or differentially modulated...

journal_title：Neuroscience

authors： Bayer L,Eggermann E,Serafin M,Grivel J,Machard D,Muhlethaler M,Jones BE

更新日期：2005-01-01 00:00:00

abstract：:This study aimed to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on learning and memory in a rat model of vascular dementia (VaD) and to analyze the associated mechanisms. Bilateral carotid artery occlusion (2-VO) was used to establish a rat model of VaD. High-frequency (5Hz) rTMS was pe...

journal_title：Neuroscience

authors： Zhang N,Xing M,Wang Y,Tao H,Cheng Y

更新日期：2015-12-17 00:00:00

abstract：:Nerve growth factor (NGF) synthesized in peripheral organs plays a critical role in the development and maintenance of the nervous system and also participates in processing nociceptive stimuli. Previous studies suggest that reproductive hormones may regulate the expression of NGF. Ovariectomies were performed on fema...

journal_title：Neuroscience

authors： Bjorling DE,Beckman M,Clayton MK,Wang ZY

更新日期：2002-01-01 00:00:00

abstract：:Imaging genetics has emerged as a powerful and sensitive approach to the study of functional genetic variations and brain responses in psychiatric and neurologic disorders. Ethics issues in contemporary neuroscience as they apply separately to genetics and neuroimaging have been a growing focus for research but, to da...

journal_title：Neuroscience

authors： Tairyan K,Illes J

更新日期：2009-11-24 00:00:00

abstract：:The present experiments examined the role of excitatory amino acid receptors in the orofacial stereotypy induced by direct amphetamine microinjection into the ventrolateral striatum. In these experiments, the influence of prior intra-ventrolateral striatum treatment with various excitatory amino acid antagonists on th...

journal_title：Neuroscience

authors： Kelley AE,Delfs JM

更新日期：1994-05-01 00:00:00

abstract：:Several experimental models of peripheral neuropathy show that a significant upregulation of spinal dynorphin A and its precursor peptide, prodynorphin, is a common consequence of nerve injury. A genetically modified mouse strain lacking prodynorphin does not exhibit sustained neuropathic pain after nerve injury, supp...

journal_title：Neuroscience

authors： Gardell LR,Ibrahim M,Wang R,Wang Z,Ossipov MH,Malan TP Jr,Porreca F,Lai J

更新日期：2004-01-01 00:00:00

abstract：:Neurofibrillary tangles in Alzheimer's disease are composed of hyperphosphorylated forms of the microtubule-associated protein tau. Based on biochemical criteria, several enzymes have emerged as potential tau protein kinases, including the extracellularly regulated kinases 1, 2 and 3. In situ hybridization was used to...

journal_title：Neuroscience

authors： Hollister RD,Page KJ,Hyman BT

更新日期：1997-08-01 00:00:00

abstract：:Treatment of P19 embryonal carcinoma cells with retinoic acid induces their differentiation into a population of cells consisting of neurons and other cell types normally derived from neuroectoderm. We used immunohistological and histochemical techniques to identify some of the neurotransmitters in the P19-derived neu...

journal_title：Neuroscience

authors： Staines WA,Morassutti DJ,Reuhl KR,Ally AI,McBurney MW

更新日期：1994-02-01 00:00:00

abstract：:Dopamine modulates synaptic transmission in various brain regions. The disorder of dopamine system may be related to neurodevelopmental dysfunction. However, the action of dopamine on synaptic transmission during development is largely unknown. We studied the effect of dopamine on GABAergic and glutamatergic transmiss...

journal_title：Neuroscience

authors： Noriyama Y,Ogawa Y,Yoshino H,Yamashita M,Kishimoto T

更新日期：2006-01-01 00:00:00

abstract：:Perineuronal nets (PNNs) are a form of aggregate Extracellular Matrix (ECM) in the brain. Recent evidence suggests that the postnatal deposition of PNNs may play an active role in regulating neuroplasticity and, potentially, neurological disorders. Observations of high levels of PNN expression around somas, proximal d...

journal_title：Neuroscience

authors： Chu P,Abraham R,Budhu K,Khan U,De Marco Garcia N,Brumberg JC

更新日期：2018-09-15 00:00:00

abstract：:Morphological features of nerve fibers and synapses containing GABA and [Met]enkephalin were studied at the light and electron microscopic levels in the superior cervical ganglia of rats by pre- and postembedding immunohistochemistry. Both GABA and [Met]enkephalin immunoreactivities were found in varicose nerve fibers...

journal_title：Neuroscience

authors： Párducz A,Dobó E,Joó F,Wolff JR

更新日期：1992-08-01 00:00:00