Long-term potentiation and memory processes in the psychological works of Sigmund Freud and in the formation of neuropsychiatric symptoms.

abstract：:Inflammatory damage following ICH is often attributed to microglia/macrophage activation. In many diseases, IL-4 has been proven to switch microglia/macrophages from the pro-inflammatory to the anti-inflammatory subtype. However, the role and underlying mechanism of IL-4 in ICH, especially in neuroprotection, remain u...

journal_title：Neuroscience

authors： He Y,Gao Y,Zhang Q,Zhou G,Cao F,Yao S

更新日期：2020-06-15 00:00:00

abstract：:Lampreys are jawless vertebrates, the most basal group of extant vertebrates. This phylogenetic position makes them invaluable models in comparative studies of the vertebrate central nervous system. Lampreys have been used as vertebrate models to study the neuronal circuits underlying locomotion control and axonal reg...

journal_title：Neuroscience

authors： Valle-Maroto SM,Fernández-López B,Villar-Cerviño V,Barreiro-Iglesias A,Anadón R,Rodicio MC

更新日期：2011-10-27 00:00:00

abstract：:Conduction time is typically ignored in computational models of neural network function. Here we consider the effects of conduction delays on the synchrony of neuronal activity and neural oscillators, and evaluate the consequences of allowing conduction velocity (CV) to be regulated adaptively. We propose that CV vari...

journal_title：Neuroscience

authors： Pajevic S,Basser PJ,Fields RD

更新日期：2014-09-12 00:00:00

abstract：:Iron may catalyse the production of reactive oxygen species during post-ischemic reoxygenation and subsequently lead to brain damage. Ferritin, an iron sequestering and storage protein, can also be a source of iron after ischemic insult. However, its role in ischemia-reperfusion has not been carefully investigated. In...

journal_title：Neuroscience

authors： Chi SI,Wang CK,Chen JJ,Chau LY,Lin TN

更新日期：2000-01-01 00:00:00

abstract：:The nucleus tractus solitarius is a key brain centre involved in the regulation of numerous autonomic functions. The present study has employed in vitro autoradiography and in vivo microdialysis to investigate the presence and function of nicotinic acetylcholine receptors located in the medial nucleus tractus solitari...

journal_title：Neuroscience

authors： Ashworth-Preece M,Jarrott B,Lawrence AJ

更新日期：1998-04-01 00:00:00

abstract：:A variety of neurological diseases are characterized by disturbances of the blood-brain barrier (BBB) and its transporters. We recently introduced fibroblast growth factor treated cortical organotypic slice cultures of mice as a model for in vitro studies of the blood-brain barrier and have now further characterized t...

journal_title：Neuroscience

authors： Camenzind RS,Chip S,Gutmann H,Kapfhammer JP,Nitsch C,Bendfeldt K

更新日期：2010-09-29 00:00:00

abstract：:Excitability and axon/dendrite specification are the most distinctive features in the establishment of neuronal polarization. Conditioned medium from rat sciatic nerve (CM) induced a neuronal-like morphology in PC12 cells. Here we show that CM neuritogenic activity is limited to the induction of dendrites in PC12 cell...

journal_title：Neuroscience

authors： Longart M,García L,Castillo C,Martínez JC,Medina R,Forsyth P,Malavé C

更新日期：2009-03-17 00:00:00

abstract：:Adverse environments during early life may lead to different neurophysiological and behavioral consequences, including depression and learning and memory deficits that persist into adulthood. Previously, we demonstrated that exposure to an enriched environment during adolescence mitigates the cognitive impairment obse...

journal_title：Neuroscience

authors： Cordier JM,Aguggia JP,Danelon V,Mir FR,Rivarola MA,Mascó D

更新日期：2021-01-15 00:00:00

abstract：:Inter-limb reflexes play an important role in coordinating behaviors involving different limbs. Previous studies have demonstrated that human elbow muscles express an inter-limb stretch reflex at long-latency (50-100 ms), a timing consistent with a trans-cortical linkage. Here we probe for inter-limb stretch reflexes ...

journal_title：Neuroscience

authors： Muraoka T,Kurtzer I

更新日期：2020-04-01 00:00:00

abstract：:The effects of Ptychodiscus brevis toxin (PbTx) on the Ia-alpha motoneuron synaptic transmission in neonatal rat spinal cord in vitro was examined. The stimulation of a dorsal root evoked monosynaptic (MSR) and polysynaptic reflex (PSR) potentials in the segmental ventral root in Mg2+-free medium. Superfusion with PbT...

journal_title：Neuroscience

authors： Singh JN,Deshpande SB

更新日期：2002-01-01 00:00:00

abstract：:Migraine attacks are typically described as unilateral, throbbing pain that is usually accompanied by nausea, vomiting, and exaggerated sensitivities to light, noise and smell. The headache phase of a migraine attack is mediated by activation of the trigeminovascular pathway; a nociceptive pathway that originates in t...

journal_title：Neuroscience

authors： Kagan R,Kainz V,Burstein R,Noseda R

更新日期：2013-09-17 00:00:00

abstract：:A previous study in our laboratory, involving early stage, amyloid pathology in 8-month-old transgenic mice, demonstrated a selective loss of cholinergic terminals in the cerebral and hippocampal cortices of doubly transgenic (APP(K670N,M671L)+PSl(M146L)) mice, an up-regulation in the single mutant APP(K670N,M671L) mi...

journal_title：Neuroscience

authors： Hu L,Wong TP,Côté SL,Bell KF,Cuello AC

更新日期：2003-01-01 00:00:00

abstract：:In genetically-modified Lmx1b(f/f/p) mice, selective deletion of LMX1B in Pet-1 expressing cells leads to failure of embryonic development of serotonin (5-HT) neurons. As adults, these mice have a decreased hypercapnic ventilatory response and abnormal thermoregulation. This mouse model has been valuable in defining t...

journal_title：Neuroscience

authors： Cerpa V,Gonzalez A,Richerson GB

更新日期：2014-10-24 00:00:00

abstract：:Anatomical and electrophysiological evidence has contributed to the hypothesis that microzones in the mammalian flocculus are organized to reflect control of eye movements in the planes of semicircular canals. Adult male Long-Evans rats received iontophoretic injections of FluoroGold and/or tetramethylrhodamine dextra...

journal_title：Neuroscience

authors： Balaban CD,Schuerger RJ,Porter JD

更新日期：2000-01-01 00:00:00

abstract：:The present study examined the antihyperalgesic effect of a specific inhibitor of Glycogen Synthase Kinase 3 (GSK3), AR-A014418, on the partial ligation of the sciatic nerve (PSNL), a neuropathic pain model in mice and investigated some mechanisms of action. AR-A014418 (0.01-1 mg/kg) administered by intraperitoneal ro...

journal_title：Neuroscience

authors： Mazzardo-Martins L,Martins DF,Stramosk J,Cidral-Filho FJ,Santos AR

更新日期：2012-12-13 00:00:00

abstract：:Many epidemiological studies support the notion that people who drink alcohol also smoke cigarettes and vice versa thereby suggesting a possible functional interaction between these two most widely used psychoactive substances. We have earlier demonstrated that direct intracerebellar (ICB) microinfusion of nicotine do...

journal_title：Neuroscience

authors： Taslim N,Al-Rejaie S,Saeed Dar M

更新日期：2008-11-11 00:00:00

abstract：:In the present study plastic neural responses to N-methyl-D-aspartate-induced excitotoxic lesions and the neuroprotective effects of the L-type voltage-dependent Ca(2+) channel antagonist nimodipine were investigated in the rat magnocellular nucleus basalis. Assessment of spontaneous behaviour in the elevated plus maz...

journal_title：Neuroscience

authors： Harkany T,Dijkstra IM,Oosterink BJ,Horvath KM,Abrahám I,Keijser J,Van der Zee EA,Luiten PG

更新日期：2000-01-01 00:00:00

abstract：:The hypocretin/orexin system regulates, among other things, sleep and energy homeostasis. The system is likely regulated by both homeostatic and circadian mechanisms. Little is known about local differences in the regulation of hypocretin activity. The aim of this study was to establish an optimized peptide quantifica...

journal_title：Neuroscience

authors： Justinussen JL,Holm A,Kornum BR

更新日期：2015-12-03 00:00:00

abstract：:Nitric oxide (NO) has been long assumed to play a key role in mammalian olfaction. This was based largely on circumstantial evidence, i.e. prominent staining for nitric oxide synthase (NOS) and cyclic guanosine 3',5'-cyclic monophosphate (cGMP) or soluble guanylyl cyclase, an effector enzyme activated by NO, in local ...

journal_title：Neuroscience

authors： Lowe G,Buerk DG,Ma J,Gelperin A

更新日期：2008-05-15 00:00:00

abstract：:Motor, sensory, and autonomic abnormalities are reported for toll-like receptor 9 (TLR9) knock-out (KO) mice. However, a physiological role of TLR9 in the nervous system is largely unknown. Since altered synaptic transmission can contribute to sensory and motor abnormalities, we evaluated neuromuscular junction (NMJ) ...

journal_title：Neuroscience

authors： Patel V,Patel AM,McArdle JJ

更新日期：2016-06-02 00:00:00

abstract：:A recent study has described synchronous burst discharges of dentate hilar neurons and area CA3 pyramidal cells in the presence of the convulsants 4-aminopyridine and picrotoxin in guinea-pig hippocampal slices [Müller W. and Misgeld U. (1991) J. Neurophysiol. 65, 141-147]. To examine the synchronous activity of denta...

journal_title：Neuroscience

authors： Scharfman HE

更新日期：1994-03-01 00:00:00

abstract：:The hippocampus maintains the remarkable ability to generate new neurons throughout the lifespan. Progenitor cells in the subgranular zone give rise mainly to granule cells that migrate to the granule cell layer and become mature, functionally integrated neurons. Numerous factors are capable of regulating the prolifer...

journal_title：Neuroscience

authors： Spanswick SC,Epp JR,Sutherland RJ

更新日期：2011-09-08 00:00:00

abstract：:The transport of excitatory amino acids (EAA) in CNS is performed by a family of high affinity, sodium dependent carriers. One of these transporters, excitatory amino acid carrier 1 (EAAC1), is known to be regulated by several mechanisms that modify carrier abundance on the plasma membrane. Much less is known on EAAC1...

journal_title：Neuroscience

authors： Bianchi MG,Gazzola GC,Tognazzi L,Bussolati O

更新日期：2008-02-19 00:00:00

abstract：:Biases in facial expression recognition can be reduced successfully using feedback-based training tasks. Here we investigate with event-related potentials (ERPs) at which stages of stimulus processing emotion-related modulations are influenced by training. Categorization of subtle facial expressions (morphed from neut...

journal_title：Neuroscience

authors： Pollux PM

更新日期：2016-05-13 00:00:00

abstract：:Neuron death due to deprivation of target-derived neurotrophic factors depends on protein synthesis regulated by transcription factor activity. We investigated the content and phosphorylation of activating transcription factor 2 (ATF-2) in axon-damaged retinal ganglion cells of neonatal rats. In the retina of neonatal...

journal_title：Neuroscience

authors： Ribas VT,Arruda-Carvalho M,Linden R,Chiarini LB

更新日期：2011-04-28 00:00:00

abstract：:Intracellular stimulation of single propriospinal axons evoked excitatory postsynaptic potentials (EPSPs) in lumbar motoneurons. Mean EPSP amplitudes differed by two orders of magnitude when measured in different connections. After analyzing the distribution of mean amplitudes of 47 single-fiber EPSPs, two populations...

journal_title：Neuroscience

authors： Dityatev A,Birinyi A,Puskár Z,Antal M,Clamann HP

更新日期：2001-01-01 00:00:00

abstract：:Transient global ischemia results in delayed selective neuronal death of hippocampal CA1 pyramidal cells. Glucocorticoids increase and adrenalectomy decreases the rate of neuronal death; however, they also produce changes in brain temperature, serum glucose and adrenocorticotropic hormone levels. In order to understan...

journal_title：Neuroscience

authors： Antonawich FJ,Miller G,Rigsby DC,Davis JN

更新日期：1999-01-01 00:00:00

abstract：:Exercise reduces the risk of developing a number of neurological disorders and increases the efficiency of cellular energy production. However, overly strenuous exercise produces oxidative stress. Proper oxygenation is crucial for the health of all tissues, and tight regulation of cellular oxygen is critical to balanc...

journal_title：Neuroscience

authors： Smeyne M,Sladen P,Jiao Y,Dragatsis I,Smeyne RJ

更新日期：2015-06-04 00:00:00

abstract：:Acute stress is known to evoke a discrete pattern of c-fos expression in the brain. The work reported here shows that this pattern is modified in regionally specific ways following repeated stress, and that this can be correlated with changes in telemetered heart rate, core temperature and corticosterone output that o...

journal_title：Neuroscience

authors： Chen X,Herbert J

更新日期：1995-02-01 00:00:00

abstract：:The responses in T3-4, T10-11 and L2-3 white rami to stimulation of different zones of the bulbar ventrolateral surface were maximal when the region of about 4 mm laterally to the midline was stimulated. A weak surface stimulation of all these zones elicited only a long latency response consisting of three waves. A sh...

journal_title：Neuroscience

authors： Lebedev VP,Krasyukov AV,Nikitin SA

更新日期：1986-01-01 00:00:00