Dendritic arborization and axon trajectory of neurons in the hypothalamic arcuate nucleus of the rat--updated.

abstract：:Working memory has often been modeled and conceptualized as a kind of binary (bistable) memory switch, where stimuli turn on plateau-like persistent activity in subsets of cells, in line with many in vivo electrophysiological reports. A potentially related form of bistability, termed up- and down-states, has been stud...

journal_title：Neuroscience

authors： Durstewitz D,Seamans JK

更新日期：2006-04-28 00:00:00

abstract：:Children exposed to extreme early-life neglect such as in institutional rearing are at heightened risk for developing depression and anxiety disorders, and internalizing problems more broadly. These outcomes are believed to be due to alterations in the development of neural circuitry that supports emotion regulation. ...

journal_title：Neuroscience

authors： Bick J,Fox N,Zeanah C,Nelson CA

更新日期：2017-02-07 00:00:00

abstract：:The effect of transitory blockage of substantia nigra pars compacta glutamatergic inputs by intracranial injections of kynurenic acid were evaluated in two monkey treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The MPTP protocol was designed to mimic the gradual evolution of human Parkinson's disease...

journal_title：Neuroscience

authors： Bezard E,Boraud T,Bioulac B,Gross CE

更新日期：1997-11-01 00:00:00

abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of retinal degenerative diseases in which the final pathological feature is photoreceptor cell apoptosis. Currently, the pathogenesis of RP remains poorly understood and therapeutics are ineffective. 17β-Oestradiol (βE2) is universally acknowledged as a neuroprotectiv...

journal_title：Neuroscience

authors： Xiong YC,Chen T,Yang XB,Deng CL,Ning QL,Quan R,Yu XR

更新日期：2021-01-01 00:00:00

abstract：:Electrical stimulation of the distal stump of cut peripheral nerves is a commonly accepted way to evoke neurogenic inflammation. Nevertheless, the modulatory effect of biogenic amines and vasoactive peptides released from efferent fibres can be excluded only if the dorsal roots are stimulated. The present study was fo...

journal_title：Neuroscience

authors： Pintér E,Szolcsányi J

更新日期：1995-09-01 00:00:00

abstract：:Extracellular levels of GABA, derived from cell suspension transplants of embryonic day 14-15 rat striatal primordia implanted into the previously excitotoxically lesioned striatum, were measured using intracerebral microdialysis in halothane-anaesthetized rats. GABA overflow was monitored using loop type dialysis pro...

journal_title：Neuroscience

authors： Campbell K,Kalén P,Wictorin K,Lundberg C,Mandel RJ,Björklund A

更新日期：1993-03-01 00:00:00

abstract：:The tachykinin NK3 receptor (NK3R) is a G-protein coupled receptor that is activated, internalized, and trafficked to the nuclei of magnocellular neurons in the paraventricular nucleus of the hypothalamus (PVN) in response to acute hyperosmolarity. The lack of information on the nuclear import pathway raises concerns ...

journal_title：Neuroscience

authors： Jensen DD,Sundstrom K,Flynn FW

更新日期：2010-11-10 00:00:00

abstract：:Endopeptidase-24.11, which is identical with the common acute lymphoblastic leukemia antigen (CALLA), is a cell surface zinc metalloprotease that has the ability to hydrolyse a variety of physiologically active peptides. Interest in this enzyme is based on the view that it may play a role in the regulation of peptide ...

journal_title：Neuroscience

authors： Kioussi C,Crine P,Matsas R

更新日期：1992-09-01 00:00:00

abstract：:Net-like structures, visualized with the Golgi technique and several histochemical and immunocytochemical methods, have been described to ensheath somata, parts of dendrites and axon initial segments of various types of neurons. The origin and function of these perineuronal nets have been controversially discussed. Re...

journal_title：Neuroscience

authors： Seeger G,Brauer K,Härtig W,Brückner G

更新日期：1994-01-01 00:00:00

abstract：:The cerebellum harbors a specialized area on the roof of the fourth ventricle that is composed of glial cells and neurons that interface with the cerebrospinal fluid. This region includes the so-called ventromedial cord (VMC), which is composed of cells that are glial fibrillary acidic protein (GFAP)-positive and nest...

journal_title：Neuroscience

authors： Becerra-González M,Varman Durairaj R,Ostos Valverde A,Gualda EJ,Loza-Alvarez P,Portillo Martínez W,Gómez-González GB,Buffo A,Martínez-Torres A

更新日期：2020-07-15 00:00:00

abstract：:Three closely-linked clusters of protocadherin (Pcdh) genes (alpha, beta, and gamma) encoding more than 50 distinct mRNAs have been identified in humans and mice, and proposed to play important roles in neuronal connectivity in the CNS. The human and mouse Pcdh alpha and gamma clusters each span a region of about 300 ...

journal_title：Neuroscience

authors： Zou C,Huang W,Ying G,Wu Q

更新日期：2007-01-19 00:00:00

abstract：:Glucocorticoids serve as key stress response hormones that facilitate stress coping. However, sustained glucocorticoid exposure is associated with adverse consequences on the brain, in particular within the hippocampus. Chronic glucocorticoid exposure evokes neuronal cell damage and dendritic atrophy, reduces hippocam...

journal_title：Neuroscience

authors： Suri D,Vaidya VA

更新日期：2013-06-03 00:00:00

abstract：:The purpose of the present study was to investigate, by use of in vivo microdialysis technique, the regulatory role of galanin on acetylcholine (ACh) release in the CA1, CA3, and dentate gyrus (DG) subregions of rat dorsal and ventral hippocampus. In the ventral hippocampus, local infusions of galanin (1.5 nmol) into ...

journal_title：Neuroscience

authors： Yoshitake T,Yoshitake S,Savage S,Elvander-Tottie E,Ogren SO,Kehr J

更新日期：2011-12-01 00:00:00

abstract：:The after-effects of locomotor stimulation are a transient facilitation of locomotor initiation (the priming effect), and a transient increase in hippocampal rhythmic slow activity in the 3-6 Hz band of the theta range. The similar time course of the two effects suggests that hippocampal 3-6 Hz activity may be linked ...

journal_title：Neuroscience

authors： Sinnamon HM

更新日期：2000-01-01 00:00:00

abstract：:Numerous epidemiological studies have shown an association between pesticide exposure and the increased risk of developing Parkinson's disease. Previously we have reported that Dichlorvos exposure can induce oxidative stress, resulting in over-expression of pro-apoptotic genes and finally caspase-dependent nigrostriat...

journal_title：Neuroscience

authors： Wani WY,Sunkaria A,Sharma DR,Kandimalla RJ,Kaushal A,Gerace E,Chiarugi A,Gill KD

更新日期：2014-01-31 00:00:00

abstract：:The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...

journal_title：Neuroscience

authors： Engel AK,Tetzlaff W,Kreutzberg GW

更新日期：1988-02-01 00:00:00

abstract：:We have observed that in rat caudate-putamen nuclei, neurons immunolabeled for choline acetyltransferase were sometimes in direct apposition to unlabeled perikarya and dendrites [Pickel V. M. and Chan J. (1990) J. Neurosci. Res. 25, 263-280]. Similar juxtapositions between plasmalemmas of nerve cells each receiving in...

journal_title：Neuroscience

authors： Pickel VM,Chan J

更新日期：1991-01-01 00:00:00

abstract：:Ivane Beritashvili ("Beritoff" in Russian, and often in Western languages) was a major figure in 20th-century neuroscience. Mastering the string galvanometer, he founded the electrophysiology of spinal cord reflexes, showing that inhibition is a distinctly different process from excitation, contrary to the concepts of...

journal_title：Neuroscience

authors： Tsagareli MG,Doty RW

更新日期：2009-10-20 00:00:00

abstract：:Nerve growth factor (NGF) can augment transmitter release in sensory neurons by acutely sensitizing sensory neurons and by increasing the expression of calcitonin gene-related peptide (CGRP) over time. The current study examined the intracellular signaling pathways that mediate these two temporally distinct effects of...

journal_title：Neuroscience

authors： Park KA,Fehrenbacher JC,Thompson EL,Duarte DB,Hingtgen CM,Vasko MR

更新日期：2010-12-15 00:00:00

abstract：:We investigated functional organization of the vagus nerve (N. X)- and glossopharyngeal nerve (N. IX)-related nuclei in the embryonic rat brainstem and compared their development and spatial distribution patterns, using multiple-site optical recording with a fast voltage-sensitive dye, NK2761. Intact brainstem prepara...

journal_title：Neuroscience

authors： Momose-Sato Y,Nakamori T,Sato K

更新日期：2011-09-29 00:00:00

abstract：:Studies in humans have documented that acute acid infusion into the esophagus leads to decrease in threshold for sensations to mechanical distension of the esophagus. It is not known whether acid infusion leads to sensitization of brainstem neurons receiving synaptic input from vagal afferent fibers innervating the es...

journal_title：Neuroscience

authors： Medda BK,Sengupta JN,Lang IM,Shaker R

更新日期：2005-01-01 00:00:00

abstract：:This study examined the age-related subsequent memory effect (SME) in perceptual and semantic encoding using event-related potentials (ERPs). Seventeen younger adults and 17 older adults studied a series of Chinese characters either perceptually (by inspecting orthographic components) or semantically (by determining w...

journal_title：Neuroscience

authors： Kuo MC,Liu KP,Ting KH,Chan CC

更新日期：2014-03-07 00:00:00

abstract：:The present studies aimed to determine whether estradiol (E(2)) modulates the stimulation of cocaine- and amphetamine-regulated transcript (CART) peptide in the mesolimbic and nigrostriatal dopaminergic systems. I.c.v. administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihy...

journal_title：Neuroscience

authors： Shieh KR,Yang SC

更新日期：2008-07-17 00:00:00

abstract：:Pairing vagus nerve stimulation (VNS) with movements or sounds can direct robust plasticity in motor or auditory cortex, respectively. The degree of map plasticity is influenced by the intensity and pulse width of VNS, number of VNS-event pairings, and the interval between each pairing. It is likely that these paramet...

journal_title：Neuroscience

authors： Loerwald KW,Buell EP,Borland MS,Rennaker RL 2nd,Hays SA,Kilgard MP

更新日期：2018-09-15 00:00:00

abstract：:Stereotaxic injections of a dopamine D1 receptor agonist (SKF 38393) into different regions of the supersensitive striatum of rats with a unilateral 6-hydroxydopamine-induced lesion duplicated the systemic effects of the drug in a topographical manner. Although there was considerable overlap, it was possible to recogn...

journal_title：Neuroscience

authors： Fletcher GH,Starr MS

更新日期：1987-02-01 00:00:00

abstract：:Sigma receptor (sigmaR), known as a unique nonopiate, nonphencyclidine brain receptor, can bind diverse classes of psychotropic drugs, neurosteroids and other synthetic compounds, such as (+)pentazocine, etc. Two types of sigmaRs have been identified: sigmaR1 and sigmaR2. In this work, we examined the expression of si...

journal_title：Neuroscience

authors： Liu LL,Wang L,Zhong YM,Yang XL

更新日期：2010-06-02 00:00:00

abstract：:Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived. Recent evidence supports the hypothesis that tinnitus is related to neuronal hyperactivity in auditory brain regions, and consequently drugs that increase GABAergic neurotransmission in the CNS, such as the GABA(B) receptor a...

journal_title：Neuroscience

authors： Zheng Y,McPherson K,Smith PF

更新日期：2014-01-31 00:00:00

abstract：:Dementia, especially Alzheimer's disease, is a rapidly increasing medical condition that presents with enormous challenge for treatment. It is characterized by impairment in memory and cognitive function often accompanied by changes in synaptic transmission and plasticity in relevant brain regions such as the hippocam...

journal_title：Neuroscience

authors： Nashawi H,Bartl T,Bartl P,Novotny L,Oriowo MA,Kombian SB

更新日期：2012-09-18 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) produce widespread and complex effects on neocortex excitability. We studied how heteromeric nAChRs regulate inhibitory post-synaptic currents (IPSCs), in fast-spiking (FS) layer V neurons of the mouse frontal area 2 (Fr2). In the presence of blockers of ionotropic glutamate ...

journal_title：Neuroscience

authors： Aracri P,Meneghini S,Coatti A,Amadeo A,Becchetti A

更新日期：2017-01-06 00:00:00

abstract：:A previous study investigating potential adult hippocampal neurogenesis in microchiropteran bats failed to reveal a strong presence of this neural trait. As microchiropterans have a high field metabolic rate and a small body mass, it is possible that capture/handling stress may lead to a decrease in the detectable pre...

journal_title：Neuroscience

authors： Chawana R,Alagaili A,Patzke N,Spocter MA,Mohammed OB,Kaswera C,Gilissen E,Bennett NC,Ihunwo AO,Manger PR

更新日期：2014-09-26 00:00:00