Analysis of synaptic events in the mouse accessory olfactory bulb with current source-density techniques.

abstract：:Substance P is known to elicit diverse actions via activating multiple subtypes of tachykinin receptors, and these actions appear to be involved not only in synaptic transmission but also in synaptic plasticity during development of the mammalian central nervous system. The availability of sensitive quantitation of in...

journal_title：Neuroscience

authors： Taoka M,Song SY,Kubota M,Minegishi A,Yamakuni T,Konishi S

更新日期：1996-10-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder, with no effective method for its treatment so far. The pathogenesis of AD has been reported, but the endogenous metabolic profile and disease-related biomarkers are still not clear. To better understand AD, an AD model induced by injecting β-amyloid...

journal_title：Neuroscience

authors： Liu Y,Wei M,Yue K,Hu M,Li S,Men L,Pi Z,Liu Z,Liu Z

更新日期：2018-12-01 00:00:00

abstract：:An increased frequency of apolipoprotein E E4 allele has been reported in patients with late onset Alzheimer's disease. Apolipoprotein E participates in the transport of cholesterol and other lipids and interferes with the growth and regeneration of both peripheral and central nervous system tissues during development...

journal_title：Neuroscience

authors： Lehtovirta M,Laakso MP,Soininen H,Helisalmi S,Mannermaa A,Helkala EL,Partanen K,Ryynänen M,Vainio P,Hartikainen P

更新日期：1995-07-01 00:00:00

abstract：:Oxytocin regulates partner preference formation and alloparental behavior in the socially monogamous prairie vole (Microtus ochrogaster) by activating oxytocin receptors in the nucleus accumbens of females. Mating facilitates partner preference formation, and oxytocin-immunoreactive fibers in the nucleus accumbens hav...

journal_title：Neuroscience

authors： Ross HE,Cole CD,Smith Y,Neumann ID,Landgraf R,Murphy AZ,Young LJ

更新日期：2009-09-15 00:00:00

abstract：:The present study was designed to investigate involvement of angiotensin II (Ang II) type 2 receptors (AT2 receptors) in restoration of perivascular nerve innervation injured by topical phenol treatment. Male Wistar rats underwent in vivo topical application of 10% phenol around the superior mesenteric artery. After p...

journal_title：Neuroscience

authors： Hobara N,Goda M,Yoshida N,Takatori S,Kitamura Y,Mio M,Kawasaki H

更新日期：2007-12-12 00:00:00

abstract：:The present paper looks for kinematic similarities between whole-body and arm movements executed in the sagittal plane. Eight subjects performed sit-to-stand (STS) and back-to-sit (BTS) movements at their preferred speed in the sagittal plane. Kinematics analysis focused on shoulder motion revealed that STS was compos...

journal_title：Neuroscience

authors： Papaxanthis C,Dubost V,Pozzo T

更新日期：2003-01-01 00:00:00

abstract：:Prestin (SLC26a5) is an integral membrane motor protein in outer hair cells (OHC) that underlies cochlear amplification. As a voltage-dependent protein, it relies on intrinsic sensor charge to respond to transmembrane voltage (receptor potentials), thereby effecting conformational changes. The protein's electromechani...

journal_title：Neuroscience

authors： Zhai F,Song L,Bai JP,Dai C,Navaratnam D,Santos-Sacchi J

更新日期：2020-04-01 00:00:00

abstract：:l-glutamate, an umami taste substance, is a key molecule coupled to a food intake signaling pathway. Furthermore, recent studies have unveiled new roles for dietary glutamate on gut-brain axis communication via activation of gut glutamate receptors and subsequent vagus nerve. In the present study, we mapped activation...

journal_title：Neuroscience

authors： Otsubo H,Kondoh T,Shibata M,Torii K,Ueta Y

更新日期：2011-11-24 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune disease in which more than 70% of patients experience visual disturbance as the earliest symptoms. Lysolecithin (LPC)-induced focal demyelination model has been developed to evaluate the effects of different therapies on myelin repair improvement. In this study, the effects of ...

journal_title：Neuroscience

authors： Daneshdoust D,Khalili-Fomeshi M,Ghasemi-Kasman M,Ghorbanian D,Hashemian M,Gholami M,Moghadamnia A,Shojaei A

更新日期：2017-03-06 00:00:00

abstract：:Origins and pathways of cerebrovascular substance P- and calcitonin gene-related peptide-positive nerves in rat were studied by immunohistochemistry combined with denervation experiments and retrograde axonal tracer technique. The two peptides have been found to coexist in one and the same neuron. After sectioning of ...

journal_title：Neuroscience

authors： Suzuki N,Hardebo JE,Owman C

更新日期：1989-01-01 00:00:00

abstract：:Protein F1/GAP-43 is a protein kinase C substrate associated with axonal growth and synaptic plasticity. We used in situ hybridization in rat brain to determine the cellular distribution of its gene expression. Throughout the septotemporal axis of the adult hippocampus, pyramidal cells express F1/GAP-43 mRNA, but gran...

journal_title：Neuroscience

authors： Meberg PJ,Routtenberg A

更新日期：1991-01-01 00:00:00

abstract：:In contrast to other rhythmic tasks such as running, the preferred movement rate in cycling does not minimize energy consumption. It is possible that neurophysiological mechanisms contribute to the choice of cadence, however this phenomenon is not well understood. Eleven participants cycled at a fixed workload of 125 ...

journal_title：Neuroscience

authors： Sidhu SK,Lauber B

更新日期：2020-08-10 00:00:00

abstract：:In some brain regions, previous studies reported the frequent coexistence between neuronal nitric oxide synthase (nNOS) and somatostatin (SOM). In the hippocampus, nNOS and SOM were mainly expressed in GABAergic nonprincipal neurons. Here we estimated the immunocytochemical colocalization of nNOS and SOM in the mouse ...

journal_title：Neuroscience

authors： Jinno S,Kosaka T

更新日期：2004-01-01 00:00:00

abstract：:In the present autoradiographic study, we took advantage of 5-hydroxytryptamine(7) (5-HT(7)) receptor knockout mice to analyze the brain distribution of 5-HT(7) receptor binding sites using [(3)H]5-carboxamidotryptamine (5-CT; a 5-HT(1A/1B/1D/5/7) receptor ligand) and [(3)H]8-hydroxy-2-(di-n-propylamino)tetralin (8-OH...

journal_title：Neuroscience

authors： Bonaventure P,Nepomuceno D,Hein L,Sutcliffe JG,Lovenberg T,Hedlund PB

更新日期：2004-01-01 00:00:00

abstract：:Long-term changes in synaptic transmission between neurons in the brain are considered the cellular basis of learning and memory. Over the last few decades, many studies have revealed that the precise order and timing of activity between pre- and post-synaptic cells ("spike-timing-dependent plasticity; STDP") is cruci...

journal_title：Neuroscience

authors： Fuenzalida M,Chiu CQ,Chávez AE

更新日期：2020-08-20 00:00:00

abstract：:This study shows that the neurons of the entopeduncular nucleus are derived from a longitudinal slab of isochronically generated neurons on day 11 and 15 h of gestation. Many neurons of this longitudinal slab which we have named the basal forebrain cell column, originate from an ependymal matrix closely associated wit...

journal_title：Neuroscience

authors： Marchand R,Lajoie L,Blanchet C

更新日期：1986-03-01 00:00:00

abstract：:Within the D2-class of dopamine receptors, the D2 and D3 subtypes share the highest degree of similarity in their primary structure. However, the extent to which these two receptor subtypes have similar or different functional properties is unclear. The present study used gene targeting to generate mice deficient for ...

journal_title：Neuroscience

authors： Jung MY,Skryabin BV,Arai M,Abbondanzo S,Fu D,Brosius J,Robakis NK,Polites HG,Pintar JE,Schmauss C

更新日期：1999-01-01 00:00:00

abstract：:We explored the contribution of inhibitory peanut-binding extracellular matrix glycoproteins to the regeneration of characteristic outgrowth patterns by different types of identified neurons. Adult leech neurons were isolated one by one and plated in culture on a substrate that consisted of the capsules that encase th...

journal_title：Neuroscience

authors： Flores-Abreu N,Vargas J,De-Miguel FF

更新日期：2006-01-01 00:00:00

abstract：:Previous findings, mainly in in vitro systems, have shown that the density of vesicles and the synaptic efficacy at excitatory synapses are reduced in the absence of synapsins, despite the fact that transgenic mice lacking synapsins develop an epileptic phenotype. Here we study glutamate receptors by quantitative immu...

journal_title：Neuroscience

authors： Gylterud Owe S,Bogen IL,Walaas SI,Storm-Mathisen J,Bergersen LH

更新日期：2005-01-01 00:00:00

abstract：:Despite an abundance of studies on mechanisms of behavioral sensitization, considerable uncertainty exists as to whether alterations in dopamine neurotransmission underlie the exacerbated behavioral effects of cocaine observed during the early stages of abstinence. One of the factors contributing to the uncertainty an...

journal_title：Neuroscience

authors： Chefer VI,Shippenberg TS

更新日期：2002-01-01 00:00:00

abstract：:The purpose of the present study was to identify processes of plasticity in the receptive field of neurosecretory neurons of the supraoptic nucleus during hibernation in the hedgehog, in order to correlate them with the increased neurosecretory activity observed in this nucleus during this annual period. Using the Rap...

journal_title：Neuroscience

authors： Sanchez-Toscano F,Caminero AA,Machin C,Abella G

更新日期：1989-01-01 00:00:00

abstract：:Acute and chronic exposure to psychostimulants results in altered function of G-protein-coupled receptors in the forebrain. It is believed that neuroadaptations in G-protein signaling contribute to behavioral sensitivity to psychostimulants that persists over a prolonged drug-free period. Proteins termed activators of...

journal_title：Neuroscience

authors： Schwendt M,McGinty JF

更新日期：2010-06-16 00:00:00

abstract：:Rat cerebrocortical minislices were incubated with physiological saline in the absence or presence of 5 mM ammonium acetate ("ammonia") and/or inhibitors of osmosensitive amino acid transport: 50 microM niflumic acid and 100 microM N-ethyl-maleimide for 60 min, with medium changes after 20 min and 40 min. The efflux o...

journal_title：Neuroscience

authors： Zielińska M,Hilgier W,Law RO,Goryński P,Albrecht J

更新日期：1999-01-01 00:00:00

abstract：:Activity-regulated, cytoskeletal-associated protein (Arc) is an immediate early gene induced in excitatory circuits following behavioral episodes. Arc mRNA is targeted to activated regions of the dendrite after long-term potentiation (LTP) of the dentate gyrus, a process dependent on NMDA receptor activation. We used ...

journal_title：Neuroscience

authors： Moga DE,Calhoun ME,Chowdhury A,Worley P,Morrison JH,Shapiro ML

更新日期：2004-01-01 00:00:00

abstract：:Extracellular nucleotides exert their actions via two subfamilies of purinoceptors: P2X and P2Y. Eight mammalian P2Y receptor subtypes (P2Y(1,2,4,6,11,12,13,14)) have been identified. In this work, the localization of P2Y(6) was studied in rat retina using double immunofluorescence labeling and confocal scanning micro...

journal_title：Neuroscience

authors： Zhang PP,Yang XL,Zhong YM

更新日期：2012-09-18 00:00:00

abstract：:Superior olivary complex (SOC) neurons receive excitatory and inhibitory inputs from both ears. We determined the nature of such inputs to the main SOC nuclei with an optical imaging system. To do so, brainstem slices of postnatal (P) rats (P3-13) were treated with the fast voltage-sensitive dye RH795, and ipsilateral...

journal_title：Neuroscience

authors： Srinivasan G,Friauf E,Löhrke S

更新日期：2004-01-01 00:00:00

abstract：:Despite extensive investigations into the mechanisms of aerobic respiration in mitochondria, the spontaneous metabolic activity of individual cells within a whole animal has not been observed in real time. Consequently, little is known about whether and how the level of mitochondrial energy metabolism is regulated in ...

journal_title：Neuroscience

authors： Kazama H,Ichikawa A,Kohsaka H,Morimoto-Tanifuji T,Nose A

更新日期：2008-03-03 00:00:00

abstract：:Acoustic trauma is the major cause of hearing loss in industrialised nations. We show in guinea-pigs that sound exposure (6 kHz, 120 dB sound pressure level for 30 min) leads to sensory cell death and subsequent permanent hearing loss. Ultrastructural analysis reveals that degeneration of the noise-damaged hair cells ...

journal_title：Neuroscience

authors： Wang J,Dib M,Lenoir M,Vago P,Eybalin M,Hameg A,Pujol R,Puel JL

更新日期：2002-01-01 00:00:00

abstract：:Regret and relief are associated with counterfactual thinking and are sensitive to various social contexts. In the present fMRI study, we investigated the neural basis for regret and relief and how social context (following vs. not following advice) modulates them by employing a sequential risk-taking task. Participan...

journal_title：Neuroscience

authors： Liu Z,Li L,Zheng L,Hu Z,Roberts ID,Guo X,Yang G

更新日期：2016-07-07 00:00:00

abstract：:The bed nucleus of stria terminalis is a basal forebrain region involved in regulation of hormonal and behavioral responses to stress. In this report we demonstrate that bed nucleus of stria terminalis has a high and localized expression of tissue plasminogen activator, a serine protease with neuromodulatory propertie...

journal_title：Neuroscience

authors： Matys T,Pawlak R,Strickland S

更新日期：2005-01-01 00:00:00