Neuronal plasticity in the hedgehog supraoptic nucleus during hibernation.

abstract：:Miniature endplate potentials were recorded from the isolated pectoralis cutaneous muscle of the frog during very stable recording conditions and low noise levels. Two to 5 x 10(3) miniature endplate potentials were filmed at eight unstressed junctions that met rigorous experimental criteria for analysis. Seven juncti...

journal_title：Neuroscience

authors： Kriebel ME,Motelica-Heino I

更新日期：1987-11-01 00:00:00

abstract：:Intense electrical activity throughout the brain which results from generalized epileptic or kindled seizures is thought to cause persistent and widespread neuronal plastic changes. We have previously reported that stage 5 kindled seizures cause an increase in vasopressin messenger RNA content and nitric oxide synthas...

journal_title：Neuroscience

authors： Al-Ghoul WM,Meeker RB,Greenwood RS

更新日期：1997-04-01 00:00:00

abstract：:p53 and parkin are involved in mitochondrial quality control. The present study aimed to characterize the functional significance of parkin/p53 in the development of mitochondrial dysfunction and the pathophysiology of neuropathic pain in type I diabetes. Type I diabetes was induced in mice (N = 170) using streptozoto...

journal_title：Neuroscience

authors： Yamashita A,Matsuoka Y,Matsuda M,Kawai K,Sawa T,Amaya F

更新日期：2019-09-15 00:00:00

abstract：:Recent findings indicate that neurosteroids could act as important keys during the brain development. Fluctuations in neonatal allopregnanolone (AlloP) could result in altered pharmacological properties of the GABA(A) receptor system in adulthood. Recent studies demonstrated that neurosteroids play a critical role in ...

journal_title：Neuroscience

authors： Martín-García E,Darbra S,Pallarés M

更新日期：2008-07-17 00:00:00

abstract：:During early embryonic development, the olfactory placode is the source of different cell types migrating toward the telencephalic vesicle. Among these cell types are the ensheathing cells, the luteinizing hormone-releasing hormone-producing cells and the olfactory marker protein-immunoreactive cells. We have identifi...

journal_title：Neuroscience

authors： De Carlos JA,López-Mascaraque L,Valverde F

更新日期：1995-10-01 00:00:00

abstract：:Peripheral nerve injury in a limb usually causes functional reorganization of the contralateral motor cortex. However, a dynamic process of the novel transhemispheric functional reorganization in the motor cortex was found in adult rats after transferring the seventh cervical nerve root from the contralateral healthy ...

journal_title：Neuroscience

authors： Lou L,Shou T,Li Z,Li W,Gu Y

更新日期：2006-01-01 00:00:00

abstract：:Incubation of the rat sensory neuron-derived cell line ND7 in serum-free medium results in the arrest of mitosis and the appearance of numerous neuronal processes. During this differentiation event, secretory granule components such as chromogranins, neuropeptide Y and the C-flanking peptide of pro-neuropeptide Y move...

journal_title：Neuroscience

authors： Wheatley SC,Suburo AM,Horn DA,Vucicevic V,Terenghi G,Polak JM,Latchman DS

更新日期：1992-12-01 00:00:00

abstract：:Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fibroblast growth factor-inducible 14 (Fn14) are expressed in neurons. Here we demonstrate that TWEAK induces a dose-dependent increase in neuronal death and that this effect is independent of tumor necrosis factor alpha (TNF-α) and mediated...

journal_title：Neuroscience

authors： Haile WB,Echeverry R,Wu F,Guzman J,An J,Wu J,Yepes M

更新日期：2010-12-29 00:00:00

abstract：:The possible roles of G-protein coupled metabotropic glutamate receptors in central nervous function are currently the focus of intensive investigation. The complexity of effects produced by agonists at these receptors probably reflects the activity of a range of sub-types. The metabotropic glutamate receptors first d...

journal_title：Neuroscience

authors： Birse EF,Eaton SA,Jane DE,Jones PL,Porter RH,Pook PC,Sunter DC,Udvarhelyi PM,Wharton B,Roberts PJ

更新日期：1993-02-01 00:00:00

abstract：:In the present study we have investigated the possible role of gap junctions in the induction and manifestation of 4-aminopyridine-induced acute seizure activity both at the primary focus and at the mirror focus in anaesthetized rats by combining electrophysiological, pharmacological and molecular biological technique...

journal_title：Neuroscience

authors： Szente M,Gajda Z,Said Ali K,Hermesz E

更新日期：2002-01-01 00:00:00

abstract：:How seizures arise and recur in epilepsy is unknown. Recent genetic, pharmacological and electrophysiological data indicate a significant but undisclosed role for voltage-dependent calcium channels. Since the contribution such channels make to nerve function reflects the targeting of discrete subtypes to distinct cell...

journal_title：Neuroscience

authors： Bernstein GM,Mendonça A,Wadia J,Burnham WM,Jones OT

更新日期：1999-01-01 00:00:00

abstract：:The first Kavli Prize in Neuroscience recognizes a confluence of career achievements that together provide a fundamental understanding of how brain and spinal cord circuits are assembled during development and function in the adult. The members of the Kavli Neuroscience Prize Committee have decided to reward three sci...

journal_title：Neuroscience

authors： Glover JC

更新日期：2009-11-10 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1), vanilloid 2 (TRPV2) and melastatin 8 (TRPM8) are thermosensitive cation channels expressed on primary sensory neurons. In contrast to TRPV1, which is present on nociceptive primary afferents and keratinocytes in human skin, less is known about the distribution of TRPV2...

journal_title：Neuroscience

authors： Axelsson HE,Minde JK,Sonesson A,Toolanen G,Högestätt ED,Zygmunt PM

更新日期：2009-09-15 00:00:00

abstract：:Hypocretin/orexin (Hcrt/Orx) and melanin concentrating hormone (MCH) are peptides contained in overlapping cell groups of the lateral hypothalamus and commonly involved in regulating sleep-wake states and energy balance, though likely in different ways. To see if these neurons are similarly or differentially modulated...

journal_title：Neuroscience

authors： Bayer L,Eggermann E,Serafin M,Grivel J,Machard D,Muhlethaler M,Jones BE

更新日期：2005-01-01 00:00:00

abstract：:Accumulation of mutant ubiquitin-B (UBB(+1)) in neurons is considered the hallmark of proteasomal dysfunction in neurodegenerative disorders, however no such evidence in ischemic brain has been reported. We investigated the contribution of UBB(+1) in delayed neuronal death after transient global ischemia. Transient gl...

journal_title：Neuroscience

authors： Yamashiro K,Liu R,Maeda M,Hattori N,Urabe T

更新日期：2007-06-15 00:00:00

abstract：:Using arsenazo III as an intracellular indicator to monitor the calcium transients elicited by voltage-clamp depolarizing pulse, the effect of prolonged in vitro lithium treatment on excitation--contraction coupling in frog twitch muscle fibres was investigated. Incubation in 10 mM Li+ Ringer's solution for 2 days cau...

journal_title：Neuroscience

authors： Zhu PH,Fu DX

更新日期：1990-01-01 00:00:00

abstract：:The study of architectonic differentiation in the cortex is advanced by the articulation of objective definitions based on clear features of the cortical architecture. We adopted areal density profiles as a means of sampling the cortex. On the profiles, we isolated and quantified the density of individual cortical lay...

journal_title：Neuroscience

authors： Mackey S,Petrides M

更新日期：2009-03-31 00:00:00

abstract：:Brain structural connectivity is known to be altered in cases of intrauterine growth restriction and premature birth, although the specific effect of maternal nutritional restriction, a common burden in human populations, has not been assessed yet. Here we analyze the effects of maternal undernutrition during pregnanc...

journal_title：Neuroscience

authors： Barbeito-Andrés J,Gleiser PM,Bernal V,Hallgrímsson B,Gonzalez PN

更新日期：2018-06-01 00:00:00

abstract：:The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal. Instead of their normal location in the intermediolateral column, the majority of SPN in the reeler cluster around the central canal. To determine whether ectopically located SPN in the reeler form approp...

journal_title：Neuroscience

authors： Yip YP,Rinaman L,Capriotti C,Yip JW

更新日期：2003-01-01 00:00:00

abstract：:The role of nitric oxide (NO) in post-ischemic cerebral infarction has been extensively examined, but few studies have investigated its role on the neurological deficit. In the present study, we investigated the effect of spermine on the temporal evolution of infarct volume, NO production and neurological deficit usin...

journal_title：Neuroscience

authors： Shirhan MD,Moochhala SM,Ng PY,Lu J,Ng KC,Teo AL,Yap E,Ng I,Hwang P,Lim T,Sitoh YY,Rumpel H,Jose R,Ling E

更新日期：2004-01-01 00:00:00

abstract：:Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the human disease multiple sclerosis (MS), a demyelinating and neurodegenerative pathology of the central nervous system. Both diseases share physiopathological and clinical characteristics, mainly associated with a neuroinflammatory pro...

journal_title：Neuroscience

authors： Chanaday NL,Roth GA

更新日期：2016-02-09 00:00:00

abstract：:In unanesthetized cats it has been found that pyramidal volleys elicited upon medullary pyramidal tract stimulation were capable of modifying the discharge of 41% of intracerebellar nuclear cells, via pontocerebellar systems impinging predominantly on the lateral cerebellar cortex. The incidence of responsive cells wa...

journal_title：Neuroscience

authors： Giuffrida R,Licata F,Li Volsi G,Perciavalle V,Urbano A

更新日期：1983-06-01 00:00:00

abstract：:Parkinson's disease patients who suffer from freezing of gait (PD-FOG) may have sensory and/or perceptual deficits, although they are difficult to disentangle. This study evaluated whether visuospatial perception or self-motion perception were more impaired in PD-FOG, and whether distance estimation errors might be re...

journal_title：Neuroscience

authors： Ehgoetz Martens KA,Ellard CG,Almeida QJ

更新日期：2014-08-22 00:00:00

abstract：:Rats were trained in a specially designed apparatus to detect brief, unpredictable visual stimuli presented to either side of the head. In one condition, rats reported the detection of the visual stimulus by removing their heads from a central location and responding in one of two adjacent side-holes where the visual ...

journal_title：Neuroscience

authors： Carli M,Jones GH,Robbins TW

更新日期：1989-01-01 00:00:00

abstract：:The effects of treatment with the antidepressant drug imipramine on neuropeptide Y immunoreactivity were studied immunocytochemically in the rat brain cortex and hypothalamus. It was found that the level of neuropeptide Y immunoreactivity in the cortex was significantly lowered three and 24 h after the last dose of ch...

journal_title：Neuroscience

authors： Smiałowska M,Legutko B

更新日期：1991-01-01 00:00:00

abstract：:Incubation of PC12 cells with S-100 protein induces a rapid (0.5-1.0 min) rise of intracellular Ca2+ which lasts for the whole period of incubation. This effect is abolished in a Ca(2+)-free medium or in the presence of 1.0 microM Ni2+, an inhibitor of calcium channels. The rise in intracellular Ca2+ is followed by a ...

journal_title：Neuroscience

authors： Mariggió MA,Fulle S,Calissano P,Nicoletti I,Fanó G

更新日期：1994-05-01 00:00:00

abstract：:The effect of the intrathecal administration of the catecholaminergic neurotoxin 6-hydroxydopamine, or of hemisection of the spinal cord at the Cl level, on the density of alpha 2-adrenoceptors and on the norepinephrine, dopamine, and serotonin content in the cat lumbar spinal enlargement was determined 2, 7 or 21 day...

journal_title：Neuroscience

authors： Howe JR,Yaksh TL,Tyce GM

更新日期：1987-05-01 00:00:00

abstract：:The distribution of axons according to diameter has been examined in the optic nerve of old world monkeys. Axon diameters were measured from electron micrographs, and histograms were constructed at regular intervals across a section through the optic nerve to reveal the local axon diameter distribution. The total axon...

journal_title：Neuroscience

authors： Reese BE,Ho KY

更新日期：1988-10-01 00:00:00

abstract：:Previous studies show that most short thoracic propriospinal (TPS; T5-T7) and long descending propriospinal tract (LDPT; C4-C6) neurons are lost following low-thoracic spinal cord contusion injury (cSCI), as assessed by retrograde labeling with fluorogold (FG). Gene microarray and terminal deoxynucleotidyl transferase...

journal_title：Neuroscience

authors： Conta Steencken AC,Smirnov I,Stelzner DJ

更新日期：2011-10-27 00:00:00

abstract：:Enkephalins are peptides which have pharmacological properties similar to those of morphine. Guinea pigs were immunized with a leucine-enkephalin/thyroglobulin conjugate. Immunofluorescence histochemistry with antiserum revealed a widely distributed system of axons and their terminals in the nervous system of the rat....

journal_title：Neuroscience

authors： Elde R,Hökfelt T,Johansson O,Terenius L

更新日期：1976-08-01 00:00:00