Abstract：
:The effects of treatment with the antidepressant drug imipramine on neuropeptide Y immunoreactivity were studied immunocytochemically in the rat brain cortex and hypothalamus. It was found that the level of neuropeptide Y immunoreactivity in the cortex was significantly lowered three and 24 h after the last dose of chronic (14 days) imipramine administration as well as 3 h after acute administration. A tendency to decrease neuropeptide Y immunoreactivity was also found in the hypothalamus. The results obtained suggest an important role of the cortical neuropeptide Y in the action of the drug.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Smiałowska M,Legutko Bdoi
10.1016/0306-4522(91)90366-vsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
767-71issue
2-3eissn
0306-4522issn
1873-7544pii
0306-4522(91)90366-Vjournal_volume
41pub_type
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