Identification of sensory nerve cells in a peripheral organ (the intestine) of a mammal.

Abstract:

:It is commonly believed that the cell bodies of mammalian sensory neurons are contained within spinal and cranial sensory ganglia associated with the central nervous system or within the central nervous system itself. However, strong circumstantial evidence implies that some sensory neurons are contained entirely within the gastrointestinal tract. We have investigated this possibility by using intracellular methods to record the responses of myenteric neurons in the guinea-pig small intestine to physiological stimuli applied to the neighbouring mucosa. The results show that the myenteric plexus contains a population of chemosensitive sensory neurons and that these neurons correspond to neurons with AH electrophysiological properties and Dogiel type II morphology. This is the first direct evidence that some sensory neurons are contained entirely within the peripheral nervous system.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Kunze WA,Bornstein JC,Furness JB

doi

10.1016/0306-4522(95)00067-s

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

1-4

issue

1

eissn

0306-4522

issn

1873-7544

pii

030645229500067S

journal_volume

66

pub_type

杂志文章