Description of the sub-miniature endplate potential distribution, determination of subunit size and number of subunits in the adult frog neuromuscular bell-miniature endplate potential.

abstract：:Using microdialysis from medial prefrontal cortex of gerbils during aversive auditory conditioning in the shuttle-box we have previously shown a transient increase of dopamine efflux correlated with the establishment of avoidance behavior. We hypothesized that the acquisition of a new behavioral strategy is generally ...

journal_title：Neuroscience

authors： Stark H,Rothe T,Wagner T,Scheich H

更新日期：2004-01-01 00:00:00

abstract：:There are declines in the protein expression of the NR2B (mouse epsilon2) and NR1 (mouse zeta1) subunits of the N-methyl-D-aspartate (NMDA) receptor in the cerebral cortex and hippocampus during aging in C57BL/6 mice. This study was designed to determine if there is a greater effect of aging on subunit expression and ...

journal_title：Neuroscience

authors： Zhao X,Rosenke R,Kronemann D,Brim B,Das SR,Dunah AW,Magnusson KR

更新日期：2009-09-15 00:00:00

abstract：:Serotonin and gamma-aminobutyric acid (GABA) neurons in the nucleus raphe dorsalis were identified by immunocytochemistry using antibodies to 5-hydroxytryptamine or GABA. The pattern of the 5-hydroxytryptamine and GABA immunostaining presented similar features: 5-hydroxytryptamine or GABA immunoreactive somata were fu...

journal_title：Neuroscience

authors： Harandi M,Aguera M,Gamrani H,Didier M,Maitre M,Calas A,Belin MF

更新日期：1987-04-01 00:00:00

abstract：:The main action of organophosphorous insecticides is generally believed to be the inhibition of acetylcholinesterase (AChE). However, these compounds also inhibit many other enzymes, any of which may play a role in their toxicity. We tested the neurotoxic mechanism of two organophosphorous insecticides, chlorpyrifos a...

journal_title：Neuroscience

authors： Rush T,Liu XQ,Hjelmhaug J,Lobner D

更新日期：2010-03-31 00:00:00

abstract：:The levels of 5-hydroxytryptamine and tachykinin neuropeptides substance P, neurokinin A, neurokinin B and neuropeptide K were measured in the spinal cord of rats treated by intraventricular injection of the selective serotonergic neurotoxin 5,7-dihydroxytryptamine. The spinal cord levels of 5-hydroxytryptamine as mea...

journal_title：Neuroscience

authors： Franck J,Brodin E,Fried K,Rosén A,Yamamoto Y,Fried G

更新日期：1991-01-01 00:00:00

abstract：:[3H]Glycine is actively taken up into bovine isolated adrenal medulla chromaffin cells with the subsequent catecholamine release. [3H]Glycine uptake has two interaction sites based on relative Km measurements. These sites are inherently distinct since the effects of strychnine and temperature on glycine binding are si...

journal_title：Neuroscience

authors： Yadid G,Youdim MB,Zinder O

更新日期：1993-08-01 00:00:00

abstract：:The relative content of calcitonin gene-related peptide in lumbar motoneuron cell bodies (semiquantitative immunohistochemistry) and sciatic nerve was examined in rats who had previously undergone a 16-week period of endurance training on a motor-driven treadmill. Soleus motoneurons were identified in the spinal cord ...

journal_title：Neuroscience

authors： Gharakhanlou R,Chadan S,Gardiner P

更新日期：1999-01-01 00:00:00

abstract：:Synaptic plasticity involves remodeling of extracellular matrix. This is mediated, in part, by enzymes of the matrix metalloproteinase (MMP) family, in particular by gelatinase MMP-9. Accordingly, there is a need of developing methods to visualize gelatinolytic activity at the level of individual synapses, especially ...

journal_title：Neuroscience

authors： Gawlak M,Górkiewicz T,Gorlewicz A,Konopacki FA,Kaczmarek L,Wilczynski GM

更新日期：2009-01-12 00:00:00

abstract：:The difference in visual object recognition by males and females suggests a sex-specific function in the medial prefrontal cortex (mPFC). In the present study, we performed an in vivo microdialysis study in three groups of rats (males, diestrous females, and proestrous females) to examine the potential sex difference ...

journal_title：Neuroscience

authors： Takase K,Kimura F,Yagami T,Mitsushima D

更新日期：2009-03-03 00:00:00

abstract：:Angiogenesis after intracerebral hemorrhage (ICH) injury can effectively alleviate brain damage and improve neurological function. Hypoxia-inducible factor 2α (HIF-2α) is an important angiogenic regulator and exhibits protective effects in several neurological diseases; however, its role in ICH has not yet been report...

journal_title：Neuroscience

authors： Chen H,Xiao H,Gan H,Zhang L,Wang L,Li S,Wang D,Li T,Zhai X,Zhao J

更新日期：2020-11-10 00:00:00

abstract：:The motor output of hypoglossal motoneurons to tongue muscles takes place in concert with the respiratory rhythm and is determined by the balance between excitatory glutamatergic transmission and inhibitory transmission mediated by glycine or GABA. The relative contribution by these transmitters is a phasic phenomenon...

journal_title：Neuroscience

authors： Pagnotta SE,Lape R,Quitadamo C,Nistri A

更新日期：2005-01-01 00:00:00

abstract：:Human acidic fibroblast growth factor (haFGF), a neurotrophin-like growth factor in the brain, plays important roles in the development, differentiation and regeneration of brain neurons, which makes it potential to treat Alzheimer's disease (AD). In this study, haFGF(14-154) and TAT-haFGF(14-154) (haFGF(14-154) fused...

journal_title：Neuroscience

authors： Lou G,Zhang Q,Xiao F,Xiang Q,Su Z,Zhang L,Yang P,Yang Y,Zheng Q,Huang Y

更新日期：2012-10-25 00:00:00

abstract：:Drugs that selectively inhibit the serotonin transporter (SERT) are widely prescribed for treatment of depression and a range of anxiety disorders. We studied the time course of changes in tryptophan hydroxylase (TPH) in four raphe nuclei after initiation of two different SERT inhibitors, citalopram and fluoxetine. In...

journal_title：Neuroscience

authors： MacGillivray L,Lagrou LM,Reynolds KB,Rosebush PI,Mazurek MF

更新日期：2010-12-01 00:00:00

abstract：:The relationship of lumbar dorsal root afferents to lateral motor column motoneurons was studied using anterograde injury filling of dorsal roots and retrograde injury filling of ventral roots with horseradish peroxidase. At the light microscopic level, horseradish peroxidase labelled dorsal root axons were observed t...

journal_title：Neuroscience

authors： Liuzzi FJ,Beattie MS,Bresnahan JC

更新日期：1984-04-01 00:00:00

abstract：:Dopamine in the prefrontal cortex plays a critical role in normal cognition throughout the lifespan and has been implicated in the pathophysiology of neuropsychiatric disorders such as schizophrenia and attention deficit disorder. Little is known, however, about the postnatal development of the dopaminergic system in ...

journal_title：Neuroscience

authors： Weickert CS,Webster MJ,Gondipalli P,Rothmond D,Fatula RJ,Herman MM,Kleinman JE,Akil M

更新日期：2007-02-09 00:00:00

abstract：:The neurotoxic organochlorine pesticides gamma-hexachlorocyclohexane, alpha-endosulfan and dieldrin induce in mammals a hyperexcitability syndrome accompanied by convulsions. They reduce the GABA-induced Cl(-) flux. The strychnine-sensitive glycine receptor also regulates Cl(-)-flux inhibitory responses. We studied th...

journal_title：Neuroscience

authors： Vale C,Fonfría E,Bujons J,Messeguer A,Rodríguez-Farré E,Suñol C

更新日期：2003-01-01 00:00:00

abstract：:Bitter taste serves as an important signal for potentially poisonous compounds in foods to avoid their ingestion. Thousands of compounds are estimated to taste bitter and presumed to activate taste receptor cells expressing bitter taste receptors (Tas2rs) and coupled transduction components including gustducin, phosph...

journal_title：Neuroscience

authors： Yoshida R,Takai S,Sanematsu K,Margolskee RF,Shigemura N,Ninomiya Y

更新日期：2018-01-15 00:00:00

abstract：:Our study examined how different housing conditions modulated the acquisition of a spatial reference memory task and also, a reversal task in the 4-radial arm water maze (4-RAWM). The animals were randomly assigned to standard or enriched cages, and, as a type of complementary stimulation along with the environmental ...

journal_title：Neuroscience

authors： Sampedro-Piquero P,Zancada-Menendez C,Begega A

更新日期：2015-10-29 00:00:00

abstract：:The piriform cortex is thought to be involved in temporal lobe seizure propagation, such as that occurring during kindling of the amygdala or hippocampus. A number of observations suggested that the circuits of the piriform cortex might act as a critical pathway for limbic seizure discharges to assess motor systems, b...

journal_title：Neuroscience

authors： Schwabe K,Ebert U,Löscher W

更新日期：2000-01-01 00:00:00

abstract：:Nociception is the neuronal process of encoding noxious stimuli and could be modulated at peripheral, spinal, brainstem, and cortical levels. At cortical levels, several areas including the anterior cingulate cortex (ACC), prefrontal cortex (PFC), ventrolateral orbital cortex (VLO), insular cortex (IC), motor cortex (...

journal_title：Neuroscience

authors： Gamal-Eltrabily M,Martínez-Lorenzana G,González-Hernández A,Condés-Lara M

更新日期：2021-01-17 00:00:00

abstract：:The mesolimbic dopaminergic system, originating from the ventral tegmental area (VTA) is implicated in the rewarding properties of ethanol. VTA dopaminergic neurons are under the tonic control of GABAergic innervations. Application of GABAergic agents changes ethanol consumption. However, it is unclear how acute ethan...

journal_title：Neuroscience

authors： Xiao C,Ye JH

更新日期：2008-04-22 00:00:00

abstract：OBJECTIVE:Women are more prone to major depressive disorders (MDDs) and the incidence of MDD in women is almost twice that of men. Insular cortex abnormalities are a common finding in neuroanatomical studies of patients with MDD. However, it remains largely unclear whether female MDD patients at different clinical stag...

journal_title：Neuroscience

authors： Liu CH,Jing B,Ma X,Xu PF,Zhang Y,Li F,Wang YP,Tang LR,Wang YJ,Li HY,Wang CY

更新日期：2014-03-14 00:00:00

abstract：:Basic fibroblast growth factor is a potent trophic factor with a wide spectrum of activity at various stages of neuronal development. In our studies on the effects of select lesions on the expression of growth factors, we observed that neurons of layer VIb of the rat cerebral cortex developed immunoreactivity for basi...

journal_title：Neuroscience

authors： Gómez-Pinilla F,Cotman CW

更新日期：1992-08-01 00:00:00

abstract：:In adult rats the mystacial vibrissae were clipped on one side of the snout, and the influence of this sensory deprivation on crossed and uncrossed striatal afferents from the substantia nigra, ventral tegmental area, and retrorubral area was examined with the horseradish peroxidase tract tracing technique. Unilateral...

journal_title：Neuroscience

authors： Steiner H,Weiler HT,Morgan S,Huston JP

更新日期：1992-01-01 00:00:00

abstract：:After transection of the sciatic nerve there is a dramatic increase in both galanin/galanin message-associated peptide-like immunoreactivities and preprogalanin messenger RNA levels in rat and mouse lumbar 4 and 5 dorsal root ganglion neurons. There is strong evidence that after nerve injury leukemia inhibitor factor ...

journal_title：Neuroscience

authors： Kerekes N,Landry M,Hökfelt T

更新日期：1999-01-01 00:00:00

abstract：:Previous research has demonstrated that diabetes induces learning and memory deficits. However, the mechanism of memory impairment induced by diabetes is poorly understood. Dietary fatty acids, especially polyunsaturated fatty acids, have been shown to enhance learning and memory and prevent memory deficits in various...

journal_title：Neuroscience

authors： Jia D,Heng LJ,Yang RH,Gao GD

更新日期：2014-01-31 00:00:00

abstract：:Cognitive deficits and psychotic symptoms are highly prevalent in patients with temporal lobe epilepsy (TLE). Imaging studies in humans have suggested that these comorbidities are associated with atrophy in temporal lobe structures and other limbic regions. It remains to be clarified whether TLE comorbidities are due ...

journal_title：Neuroscience

authors： Wolf DC,Bueno-Júnior LS,Lopes-Aguiar C,Do Val Da Silva RA,Kandratavicius L,Leite JP

更新日期：2016-01-15 00:00:00

abstract：:In the adult CNS, tissue-specific germinal niches, such as the subventricular zone of the lateral ventricles and the subgranular zone of the dentate gyrus of the hippocampus, contain multipotent neural precursor cells (NPCs) with the capacity to self-renew and differentiate into functional brain cells (i.e. neurons, a...

journal_title：Neuroscience

authors： Cristofanilli M,Cymring B,Lu A,Rosenthal H,Sadiq SA

更新日期：2013-10-10 00:00:00

abstract：:The presence of the acetylcholinesterase neurons and substance P-like and enkephalin-like fibers in the various nuclear columns of the ventral horns of the spinal cords was studied in the developing human by acetylcholinesterase histochemistry and substance P and enkephalin immunohistochemistry. Acetylcholinesterase-p...

journal_title：Neuroscience

authors： Luo CB,Yew DT,Zheng DR,Liu YQ

更新日期：1992-06-01 00:00:00

abstract：:Electron probe X-ray microanalysis was used to measure water content and concentrations of elements (i.e. Na, K, Cl and Ca) in selected morphological compartments of rat optic nerve myelinated axons. Transaxolemmal movements of Na+ and Ca2+ were modified experimentally and corresponding effects on axon element and wat...

journal_title：Neuroscience

authors： Stys PK,Lopachin RM

更新日期：1998-01-01 00:00:00