Spermine reduces infarction and neurological deficit following a rat model of middle cerebral artery occlusion: a magnetic resonance imaging study.

abstract：:Metabolic activity was mapped in the cerebellar cortex and its major inputs and projection targets in monkeys performing visually guided reaching with the left forelimb. Normal monkeys and monkeys deprived of visual input to the right cerebral hemisphere by right optic tract section, combined in some cases with forebr...

journal_title：Neuroscience

authors： Savaki HE,Kennedy C,Sokoloff L,Mishkin M

更新日期：1996-11-01 00:00:00

abstract：:Acute stress is known to evoke a discrete pattern of c-fos expression in the brain. The work reported here shows that this pattern is modified in regionally specific ways following repeated stress, and that this can be correlated with changes in telemetered heart rate, core temperature and corticosterone output that o...

journal_title：Neuroscience

authors： Chen X,Herbert J

更新日期：1995-02-01 00:00:00

abstract：:Alzheimer's disease (AD), the most common form of dementia in the elderly, is characterized by the presence of extracellular plaques composed of amyloid β (Aβ) peptides and intracellular tau aggregates. The plaques are surrounded by microglia, the brain's resident immune cells, which likely participate in the clearanc...

journal_title：Neuroscience

authors： Gyoneva S,Swanger SA,Zhang J,Weinshenker D,Traynelis SF

更新日期：2016-08-25 00:00:00

abstract：:We have measured on-line the exocytotic secretion of ATP from adrenal medullary chromaffin cells induced by Ba2+ using a luciferin/luciferase assay. We have found that Ba2+-induced ATP release requires the entry of Ba2+ through either voltage- or receptor-gated Ca2+ channels. This conclusion is based on the observatio...

journal_title：Neuroscience

authors： Forsberg EJ,Pollard HB

更新日期：1988-11-01 00:00:00

abstract：:Laminar organization is a fundamental cytoarchitecture in mammalian CNS and a striking feature of the neocortex. ER81, a transcription factor, has recently been utilized as a marker of cells in the layer 5 of the neocortex. We further pursued the distribution of ER81 to investigate the identity of the ER81-expressing ...

journal_title：Neuroscience

authors： Yoneshima H,Yamasaki S,Voelker CC,Molnár Z,Christophe E,Audinat E,Takemoto M,Nishiwaki M,Tsuji S,Fujita I,Yamamoto N

更新日期：2006-01-01 00:00:00

abstract：:Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that regulates immune and cell-survival signaling pathways. NF-κB has been reported to be present in neurons wherein it reportedly responds to immune and toxic stimuli, glutamate, and synaptic activity. However, because the brain contains many cell ty...

journal_title：Neuroscience

authors： Listwak SJ,Rathore P,Herkenham M

更新日期：2013-10-10 00:00:00

abstract：:There is increasing evidence that alterations in the focus of attention result in changes in neural responding at the most peripheral levels of the auditory system. To date, however, those studies have not ruled out differences in task demands or overall arousal in explaining differences in responding across intermoda...

journal_title：Neuroscience

authors： Srinivasan S,Keil A,Stratis K,Woodruff Carr KL,Smith DW

更新日期：2012-10-25 00:00:00

abstract：:Extensive research over the past decades has characterized multiple forms of synaptic plasticity, identifying them as key processes that allow the brain to operate in a dynamic manner. Within the wide variety of synaptic plasticity modulators, kainate receptors are receiving increasing attention, given their diversity...

journal_title：Neuroscience

authors： Valbuena S,Lerma J

更新日期：2019-12-19 00:00:00

abstract：:Olvanil ((N-vanillyl)-9-oleamide), a non-pungent transient receptor potential vanilloid type 1 agonist, desensitizes nociceptors and alleviates pain. But its molecular targets and signaling mechanisms are little known. Calcium influx through voltage-activated Ca(2+) channels plays an important role in neurotransmitter...

journal_title：Neuroscience

authors： Wu ZZ,Chen SR,Pan HL

更新日期：2006-08-11 00:00:00

abstract：:A study has been made at the ultrastructural level of the effects of denervation and axotomy on the synapse population of the rat superior cervical ganglion. Superior cervical ganglia were subjected unilaterally to acute (survival, 48 h) or chronic preganglionic denervation (survival, 41-189 days) by cutting the cervi...

journal_title：Neuroscience

authors： Ramsay DA,Matthews MR

更新日期：1985-12-01 00:00:00

abstract：:The neurotensin-containing projections from the retrosplenial cortex to the anterior ventral thalamus were demonstrated by electrolytic lesion studies and fluorescent retrograde tracing combined with immunocytochemistry. Three-to-five-day-old rats were used, because the immunoreactivity of neurotensin fibers in anteri...

journal_title：Neuroscience

authors： Fukami K,Kiyama H,Shiotani Y,Tohyama M

更新日期：1988-09-01 00:00:00

abstract：:Exposure to loud, prolonged sounds (acoustic trauma, AT) leads to the death of both inner and outer hair cells (IHCs and OHCs), death of neurons of the spiral ganglion and degeneration of the auditory nerve. The auditory nerve (8cn) projects to the three subdivisions of the cochlear nuclei (CN), the dorsal cochlear nu...

journal_title：Neuroscience

authors： Baizer JS,Wong KM,Manohar S,Hayes SH,Ding D,Dingman R,Salvi RJ

更新日期：2015-09-10 00:00:00

abstract：:Brain activities in response to acupuncture have been investigated in multiple studies; however, the neuromechanisms of low- and high-frequency transcutaneous electric acupoint stimulation (TEAS) analgesia are unclear. This work aimed to investigate how brain activity and the analgesic effect changed across 30-min low...

journal_title：Neuroscience

authors： Jiang Y,Liu J,Liu J,Han J,Wang X,Cui C

更新日期：2014-05-30 00:00:00

abstract：:Our recent data suggest that noradrenaline (NA) regulates expression of Per1 mRNA in rat C6 cells, as a model of brain astrocytes, by two distinct NA-mediating pathways. Although C6 cells possess potential astrocyte-type characteristics, we hypothesize that astrocytes located in a distinct tissue or organ play specifi...

journal_title：Neuroscience

authors： Sugimoto T,Morioka N,Sato K,Hisaoka K,Nakata Y

更新日期：2011-06-30 00:00:00

abstract：:A previously developed model of exercise-induced muscle contracture using iodoacetate to inhibit glyceraldehyde-3-phosphate dehydrogenase in rat hindlimb muscles produced selective type II myofiber damage. Utilizing a modification of the same model system, rats were given intra-aortic ortho-iodosobenzoic acid (700 nmo...

journal_title：Neuroscience

authors： Locklear I,Feeback DL,Brumback RA

更新日期：1990-01-01 00:00:00

abstract：:The postsynaptic density is a highly dynamic structure, which is reorganized in an activity-dependent manner. An animal model for temporal lobe epilepsy, i.e. kainate-induced limbic seizures in rats, was used to study changes in postsynaptic density composition after extensive synaptic activity. Six hours after kainat...

journal_title：Neuroscience

authors： Wyneken U,Smalla KH,Marengo JJ,Soto D,de la Cerda A,Tischmeyer W,Grimm R,Boeckers TM,Wolf G,Orrego F,Gundelfinger ED

更新日期：2001-01-01 00:00:00

abstract：:Nitric oxide is thought to play an important role in multiple forms of use-dependent synaptic plasticity, including that which follows noxious peripheral stimulation. This suggests that development of nociception-induced neuroplasticity should be impaired in transgenic animals lacking the neuronal form of nitric oxide...

journal_title：Neuroscience

authors： Crosby G,Marota JJ,Huang PL

更新日期：1995-12-01 00:00:00

abstract：:Neurodegeneration in Alzheimer's disease is characterized by a selective loss of particular cell populations. Several recent lines of evidence suggest that beta-amyloid protein directly contributes to the disease's progression and is likely responsible for the observed pattern of neuronal death. We have previously dem...

journal_title：Neuroscience

authors： Pike CJ,Cotman CW

更新日期：1993-09-01 00:00:00

abstract：:Neonatal inhibition of brain estrogen formation in male rats by administration of the aromatase inhibitor, 1,4,6-androstatriene-3,17-dione (ATD), permanently changes aspects of their mating behavior and partner preference in adulthood. The medial preoptic area receives chemosensory inputs via a sexually dimorphic vome...

journal_title：Neuroscience

authors： Bakker J,Baum MJ,Slob AK

更新日期：1996-09-01 00:00:00

abstract：:Changes in the amplitude of the calcium inward current caused by intracellular administration of tolbutamide (an inhibitor of the cyclic AMP-dependent protein kinase activity) or catalytic subunits of cAMP-dependent protein kinases from rabbit myocardium were studied on internally perfused nerve cells of the snail, He...

journal_title：Neuroscience

authors： Doroshenko PA,Kostyuk PG,Martynyuk AE,Kursky MD,Vorobetz ZD

更新日期：1984-01-01 00:00:00

abstract：:The present paper looks for kinematic similarities between whole-body and arm movements executed in the sagittal plane. Eight subjects performed sit-to-stand (STS) and back-to-sit (BTS) movements at their preferred speed in the sagittal plane. Kinematics analysis focused on shoulder motion revealed that STS was compos...

journal_title：Neuroscience

authors： Papaxanthis C,Dubost V,Pozzo T

更新日期：2003-01-01 00:00:00

abstract：:The hypothesis that electrotonic spread among oxytocinergic neurons contributes to synchronized bursting in the lactating rat leads to the prediction that coupling among oxytocinergic neurons would be stronger and more abundant in lactating than in non-lactating animals. We tested this prediction using, as an index of...

journal_title：Neuroscience

authors： Hatton GI,Yang QZ,Cobbett P

更新日期：1987-06-01 00:00:00

abstract：:To examine the effect of glucose on the cerebral metabolism of glutamine, rat brain slices were incubated with 5mM [3-(13)C]glutamine without and with 5mM unlabeled glucose. Tissue plus medium extracts were analyzed by using enzymatic and (13)C NMR techniques and fluxes through the enzymatic steps involved were calcul...

journal_title：Neuroscience

authors： El Hage M,Baverel G,Conjard-Duplany A,Martin G

更新日期：2013-09-17 00:00:00

abstract：:Antisera produced in rabbits against pure fractions of cholinergic vesicles from Narcine brasiliensis were used to study cholinergic organelles in rat motor neurons. The indirect immunofluorescence method was used on perfusion-fixed material. The rats were surgically sympathectomized to remove sympathetic adrenergic a...

journal_title：Neuroscience

authors： Dahlström A,Larsson PA,Carlson SS,Bööj S

更新日期：1985-02-01 00:00:00

abstract：:We have previously described a population of 5-hydroxytryptamine neurons which repetitively fires bursts of usually two (but occasionally three or four) action potentials, with a short (<20 ms) interspike interval within a regular low-frequency firing pattern. Here we used a paradigm of electrical stimulation comprisi...

journal_title：Neuroscience

authors： Gartside SE,Hajós-Korcsok E,Bagdy E,Hársing LG Jr,Sharp T,Hajós M

更新日期：2000-01-01 00:00:00

abstract：:The area postrema has been implicated as a major station for the processing of visceral sensory information, involved primarily in eliciting rapid homeostatic responses to fluid and nutrient imbalances. Yet the precise relationship of efferent projections from the area postrema to medullary motor and relay nuclei invo...

journal_title：Neuroscience

authors： Cunningham ET Jr,Miselis RR,Sawchenko PE

更新日期：1994-02-01 00:00:00

abstract：:l-glutamate, an umami taste substance, is a key molecule coupled to a food intake signaling pathway. Furthermore, recent studies have unveiled new roles for dietary glutamate on gut-brain axis communication via activation of gut glutamate receptors and subsequent vagus nerve. In the present study, we mapped activation...

journal_title：Neuroscience

authors： Otsubo H,Kondoh T,Shibata M,Torii K,Ueta Y

更新日期：2011-11-24 00:00:00

abstract：:Production of tissue inhibitors of matrix metalloproteinases (TIMPs), a family of secreted proteins with inhibitory actions on matrix metalloproteinases (MMPs), is up-regulated following nerve injuries and is suggested to have protective effects against MMP-mediated tissue damages. To clarify the extracellular signals...

journal_title：Neuroscience

authors： Koyama Y,Baba A,Matsuda T

更新日期：2007-07-13 00:00:00

abstract：:GABA immunoreactivity was studied in the optic tectum of the frog, Rana esculenta, by postembedding immunohistochemical methods at the light and electron microscopic levels. Nearly one-third of the total population of tectal cells appeared to be GABA-immunoreactive. The proportion of stained neurons was highest in lay...

journal_title：Neuroscience

authors： Antal M

更新日期：1991-01-01 00:00:00

abstract：:The rapidly inactivating A-type K+ current (IA) is prominent in hippocampal neurons; and the speed of its inactivation may regulate electrical excitability. The auxiliary K+ channel subunit Kvbeta 1.1 confers fast inactivation to Shaker-related channels and is postulated to affect IA. Whole-cell patch clamp recordings...

journal_title：Neuroscience

authors： Falk T,Kilani RK,Strazdas LA,Borders RS,Steidl JV,Yool AJ,Sherman SJ

更新日期：2003-01-01 00:00:00