Ba2+-induced ATP release from adrenal medullary chromaffin cells is mediated by Ba2+ entry through both voltage- and receptor-gated Ca2+ channels.

abstract：:Three structurally distinct groups of antagonists were used to test the hypothesis that integrin adhesion receptors play an essential role in consolidating (stabilizing) long term potentiation of the Schaffer collaterals in rat hippocampus. Comparisons were made of percent potentiation at antagonist-treated versus con...

journal_title：Neuroscience

authors： Chun D,Gall CM,Bi X,Lynch G

更新日期：2001-01-01 00:00:00

abstract：:Longevity genes attenuate the aging process, but their expression in the brain during aging remains unknown. Loss of the majority of heteromeric brain nicotinic acetylcholine receptors (nAChRs) results in premature brain aging, and altered regulation of longevity genes could be involved. Using in situ hybridization, t...

journal_title：Neuroscience

authors： Huang PS,Son JH,Abbott LC,Winzer-Serhan UH

更新日期：2011-11-24 00:00:00

abstract：:This mini-review starts with a summary of the crucial contributions Ricardo Miledi made to our understanding of how the action potential triggers fast, synchronous transmitter release. It then transitions to the discovery of synaptotagmin and its role as the exocytotic Ca2+ sensor at nerve terminals. The final section...

journal_title：Neuroscience

authors： Gundersen CB

更新日期：2020-07-15 00:00:00

abstract：:The role of serotonin1A and serotonin4 receptors in the modulation of synaptic inhibition in the dentate gyrus of guinea-pig hippocampal slices was studied. The effects of serotonin (5-hydroxytryptamine) on hilar neurons and on inhibitory postsynaptic potentials in granule cells were compared using intracellular recor...

journal_title：Neuroscience

authors： Bijak M,Misgeld U

更新日期：1997-06-01 00:00:00

abstract：:The cerebral peptidergic caudodorsal cells of the freshwater snail Lymnaea stagnalis control egg laying and egg-laying behaviour by releasing peptides into (1) the haemolymph, from neurohaemal axon terminals in the periphery of the cerebral commissure and (2) the intercellular space of the central nervous system, from...

journal_title：Neuroscience

authors： Schmidt ED,Roubos EW

更新日期：1988-07-01 00:00:00

abstract：:The distributions of the alpha 1-adrenoceptor and its subtypes (alpha 1A and alpha 1B) in human and rat hippocampus are analysed by quantitative receptor autoradiography. alpha 1-Adrenoceptors are labelled by [3H]prazosin. The alpha 1A subtype is visualized by [3H]prazosin after irreversible blockade of alpha 1B adren...

journal_title：Neuroscience

authors： Zilles K,Gross G,Schleicher A,Schildgen S,Bauer A,Bahro M,Schwendemann G,Zech K,Kolassa N

更新日期：1991-01-01 00:00:00

abstract：:The circadian pacemaker of the suprachiasmatic nuclei is a complex multioscillator system, which controls circadian and seasonal rhythmicity. A number of clock genes have been identified that play a key role in the generation of circadian rhythms. These clock genes are expressed in a circadian manner as has been shown...

journal_title：Neuroscience

authors： Schaap J,Albus H,Eilers PH,Détári L,Meijer JH

更新日期：2001-01-01 00:00:00

abstract：:Acetylcholine release in the frontal cortex of awake rats after acute or chronic lesions of the nucleus basalis magnocellularis and grafting of cholinergic-rich basal forebrain tissue was studied by in vivo microdialysis. Three to four weeks and five months after a unilateral quisqualic acid lesion of the nucleus basa...

journal_title：Neuroscience

authors： Rosenblad C,Nilsson OG

更新日期：1993-07-01 00:00:00

abstract：:Growth-associated protein-43, an established marker of neuronal plasticity during development and in injury, was used to characterize innervation in the normal human pancreas and changes in chronic alcohol-induced pancreatitis by using light microscopic immunocytochemistry and computer-assisted image analysis. Immunos...

journal_title：Neuroscience

authors： Fink T,Di Sebastiano P,Büchler M,Beger HG,Weihe E

更新日期：1994-11-01 00:00:00

abstract：:The dopamine D2 receptor (DRD2) and dopamine transporter (DAT) play a regulatory role in dopaminergic neurotransmission and thus play an important role in drug addiction. The prefrontal cortex (PFC), a critical part of the mesencephalic dopaminergic system, is thought to be involved in the development and maintenance ...

journal_title：Neuroscience

authors： Sun Z,Ma Y,Xie L,Huang J,Duan S,Guo R,Xie Y,Lv J,Lin Z,Ma S

更新日期：2019-09-01 00:00:00

abstract：:The basal forebrain (BF) comprises morphologically and functionally heterogeneous cell populations, including cholinergic and non-cholinergic corticopetal neurons that are implicated in sleep-wake modulation, learning, memory and attention. Several studies suggest that glutamate may be among inputs affecting cholinerg...

journal_title：Neuroscience

authors： Hur EE,Edwards RH,Rommer E,Zaborszky L

更新日期：2009-12-29 00:00:00

abstract：:The cholinergic agonist nicotine facilitates detection of invalidly cued trials in location-cueing paradigms and reduces the associated neural activity in human inferior parietal cortex. By using functional magnetic resonance imaging we test the hypothesis that the nicotinic modulation of attentional reorienting may r...

journal_title：Neuroscience

authors： Thiel CM,Fink GR

更新日期：2008-03-18 00:00:00

abstract：:The sphenopalatine ganglion (SPG) is a gathering of the cell bodies of parasympathetic fibers that dominate the nasal gland, lacrimal gland and cerebral blood vessels. The SPG controls nasal secretions, tears, and the dilation of cerebral blood vessels. However, it is unclear how serotonin regulates SPG functions. In ...

journal_title：Neuroscience

authors： Ishida Y,Sugiura Y,Magome T,Kamakura T,Takimoto Y,Hanada Y,Kitayama K,Nakamura Y,Shimada S,Ohta N,Naono-Nakayama R,Kamijo K

更新日期：2019-07-15 00:00:00

abstract：:The aim of the present study was to examine the modification of postural symmetry during quiet standing using a sensorimotor adaptation paradigm. A group of neurologically typical adult participants performed a visually guided mediolateral (left-right) weight shifting task requiring precise adjustments in body orienta...

journal_title：Neuroscience

authors： Shiller DM,Veilleux LN,Marois M,Ballaz L,Lemay M

更新日期：2017-07-25 00:00:00

abstract：:Limb somatosensory signals modify the discharge of vestibular neurons and elicit postural reflexes, which stabilize the body position. The aim of this study was to investigate the contribution of the γ-amino-butyric-acid (GABA) to the responsiveness of vestibular neurons to somatosensory inputs. The activity of 128 ve...

journal_title：Neuroscience

authors： Grasso C,Li Volsi G,Cataldo E,Manzoni D,Barresi M

更新日期：2016-10-29 00:00:00

abstract：:A reappraisal of the relationship between length summation and receptive field length assessed by the minimum response field method, was made in complex cells recorded from the lightly anaesthetized feline striate cortex. This relationship has previously been proposed by Gilbert [(1977) J. Physiol., Lond. 268, 391-421...

journal_title：Neuroscience

authors： Hammond P,Ahmed B

更新日期：1985-07-01 00:00:00

abstract：:A new double-label autoradiographic glucose analog method for the sequential measurement of altered regional cerebral metabolic rates for glucose in the same animal is presented. This method is based on the sequential injection of two boluses of glucose tracer labeled with two different isotopes (short-lived 18F and l...

journal_title：Neuroscience

authors： Redies C,Diksic M,Evans AC,Gjedde A,Yamamoto YL

更新日期：1987-08-01 00:00:00

abstract：:Colivelin is a neuroprotective humanin family peptide with potent long-term capacity against Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease. We seek to investigate whether this effect of Colivelin also govern ischemic brain injury, and potential mechanism underlying th...

journal_title：Neuroscience

authors： Zhao H,Feng Y,Wei C,Li Y,Ma H,Wang X,Cui Z,Jin WN,Shi FD

更新日期：2019-09-15 00:00:00

abstract：:Alternative motor responses can be prepared in parallel. Here, we used electroencephalography (EEG) to test whether the parallel preparation of alternative response options is modulated by their relative value. Participants performed a choice response task with three potential actions: isometric contraction of the lef...

journal_title：Neuroscience

authors： Reuter EM,Marinovic W,Beikoff J,Carroll TJ

更新日期：2018-03-15 00:00:00

abstract：:Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process...

journal_title：Neuroscience

authors： Wang JT,Song LZ,Li LL,Zhang W,Chai XJ,An L,Chen SL,Frotscher M,Zhao ST

更新日期：2015-04-30 00:00:00

abstract：:Studies show that maternal consumption of a high-fat diet (HFD) can impair the formation of hypothalamic neuronal circuits in mouse offspring. This damage can be mediated by Notch1/Hes5 signaling activation, leading to repression of proneural factors such as Mash1 and Ngn2/3, which are essential for neuronal different...

journal_title：Neuroscience

authors： Lemes SF,de Souza ACP,Payolla TB,Versutti MD,de Fátima da Silva Ramalho A,Mendes-da-Silva C,Souza CM,Milanski M,Torsoni AS,Torsoni MA

更新日期：2018-02-10 00:00:00

abstract：:Conduction time is typically ignored in computational models of neural network function. Here we consider the effects of conduction delays on the synchrony of neuronal activity and neural oscillators, and evaluate the consequences of allowing conduction velocity (CV) to be regulated adaptively. We propose that CV vari...

journal_title：Neuroscience

authors： Pajevic S,Basser PJ,Fields RD

更新日期：2014-09-12 00:00:00

abstract：:The effects of acute application of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNFalpha) on levels of intracellular Ca(2+) ([Ca(2+)]i) and on whole-cell outward and inward K(+) currents were studied in cultured human microglia. TNFalpha elicited a linear increase in [Ca(2+)]i to a plateau level in micr...

journal_title：Neuroscience

authors： McLarnon JG,Franciosi S,Wang X,Bae JH,Choi HB,Kim SU

更新日期：2001-01-01 00:00:00

abstract：:Although the major mode of transmission for serotonin in the brain is volume transmission, previous anatomical studies have demonstrated that serotonergic axons do form synaptic contacts. The olfactory glomeruli of the olfactory bulb of mammals receive a strong serotonergic innervation from the dorsal and medial raphe...

journal_title：Neuroscience

authors： Gracia-Llanes FJ,Blasco-Ibáñez JM,Nácher J,Varea E,Liberia T,Martínez P,Martínez-Guijarro FJ,Crespo C

更新日期：2010-08-25 00:00:00

abstract：:During rapid cell growth the availability of phospholipid precursors like cytidine triphosphate and diacylglycerol can become limiting in the formation of key membrane constituents like phosphatidylcholine. Uridine, a normal plasma constituent, can be converted to cytidine triphosphate in PC12 [corrected] cells and in...

journal_title：Neuroscience

authors： Pooler AM,Guez DH,Benedictus R,Wurtman RJ

更新日期：2005-01-01 00:00:00

abstract：:The physiological role of 5-hydroxytryptamine6 receptors in the central nervous system has not yet been elucidated. The high affinity of various psychotropic drugs for 5-hydroxytryptamine6 receptors has led to the suggestion that this receptor type may be a novel target in neuropsychiatry. We have found that continuou...

journal_title：Neuroscience

authors： Otano A,Frechilla D,Cobreros A,Cruz-Orive LM,Insausti A,Insausti R,Hamon M,Del Rio J

更新日期：1999-01-01 00:00:00

abstract：:Activation of muscarinic receptors leads to proliferation of astroglial cells and this effect is inhibited by ethanol. Among the intracellular pathways involved in the mitogenic action of muscarinic agonists, activation of the atypical protein kinase C zeta (PKC zeta) appears to be of most importance, and is also affe...

journal_title：Neuroscience

authors： Guizzetti M,Bordi F,Dieguez-Acuña FJ,Vitalone A,Madia F,Woods JS,Costa LG

更新日期：2003-01-01 00:00:00

abstract：:Diversity in social structures, from solitary to eusocial, is a prominent feature of subterranean African mole-rat species. Damaraland mole-rats are eusocial, they live in colonies that are characterized by a reproductive division of labor and a subdivision into castes based on physiology and behavior. Damaraland mole...

journal_title：Neuroscience

authors： Oosthuizen MK,Amrein I

更新日期：2016-06-02 00:00:00

abstract：:Wobbler mice are experimental models for amyotrophic lateral sclerosis. As such they show motoneuron degeneration, motor deficits, and astrogliosis and microgliosis of the spinal cord. Additionally, Wobbler mice show increased plasma, spinal cord and brain corticosterone levels and focal adrenocortical hyperplasia, su...

journal_title：Neuroscience

authors： Meyer M,Lara A,Hunt H,Belanoff J,de Kloet ER,Gonzalez Deniselle MC,De Nicola AF

更新日期：2018-08-01 00:00:00

abstract：:The aim of this study was to examine the development of the basalocortical pathway by using choline acetyltransferase and nerve growth factor receptor immunocytochemistry, acetylcholinesterase histochemistry and retrograde axonal transport. The observations were made in the ferret because in this species brain develop...

journal_title：Neuroscience

authors： Henderson Z

更新日期：1991-01-01 00:00:00